Yintoni disulfiramopodobnye yokusabela? Yintoni na ke yingozi?

Phantsi kweemeko eziqhelekileyo, xa zingene umzimba ubola ngokukhawuleza kwi metabolites utywala (iimveliso pathways ubuthi). Noko ke, ngenxa yokuba yokwamkela inani iziyobisi kuvela nezitenxo kwinkqubo ukubola. Izinga chemical. indlela iya kuxhomekeka umthamo ichiza kunye nemali utywala. Amayeza, ukuphazamiseka ingqondo, kufuneka kwaziwe ikakhulu antibiotics. Ukuselwa kotywala ngenxa yonyango kukho iziphumo ezimandla. Ezi ziquka disulfiramopodobnye basabela. Ngophuhliso ezi ziphumo kwizigulane abonakale, kunye nezinye iimpawu, Ukwehluleka iimveliso utywala-based.

Imixube eshukumisa esisabela disulfiramopodobnye

Lithetha "Trykhopol" liye antibacterial kunye nomsebenzi antiprotozoal. Xa kudityaniswe i medicament utywala ebangela imeko yesigulane kakhulu kule apho kombisa disulfiramopodobnye basabela. Le propati uvumele ukusetyenziswa medicament yonyango ka otywala ezingapheliyo. Lidla wabelwe ichiza ezifana "Amoxicillin". Olu nyango kungabangela iingxaki ukuphefumla, notywala kunganqanda umsebenzi weli ziko ebuchotsheni sokuphefumla. Kulo mba, ukuhlanganiswa mali 'Amoxicillin "notywala kwandisa amathuba ukufa abantu beyotyiwe. Kukho imithi zabelwe ngokukhethekileyo ukuze disulfiramopodobnye basabela. Ezi iziyobisi ezifana "Esperal", "Antabuse" kunye nabanye. Xa yokwamkela sabo ukutshatyalaliswa enzayim ethile. Igama livela indlela ichiza "Disulfiram". Eli yeza kwakhona, kunye nezinye iindlela ezifanayo, isetyenziselwa ukunyanga butywala ngohlobo ezigulo ezondeleyo. Imeko ukuvela xa ulwamkelo ebizwa disulfiram-utywala, ukuba nempembelelo kwicala ibangelwa amanye amayeza - disulfiramopodobnyh.

Ngenxa yeziphumo ebezingalindelekanga

Uphuhliso karhulumente ukuba sokuzuza emzimbeni imveliso kwawa ethanol - acetaldehyde. Le compound iye letyhefu eliphezulu. Phantsi kweemeko eziqhelekileyo, iyeza le bangabi phantsi intshukumo ezithile enzayim (okanye enye aldehyde). Amanye amachiza kunganqanda umsebenzi ezi zinto. Ngenxa yoko, kukho zemali acetaldehyde emzimbeni, nto leyo sikhatshwa eziliqela iimpawu isici. Xa amayeza efanayo ukuvimba isenzo lomnye uthotho enqanda. Oku, evusa ukuhla kumanqanaba noradrenaline kwinkqubo luvo kunye nokuhluthwa ubuhlobo baso dopamine. Ngenxa yoko, disulfiramopodobnye reactions ziyanyuswa nangakumbi. Iingcali uqaphele ukuba le meko iye hlobo ngokwaneleyo oluqhubekayo. Ngoko ke, oogqirha musa singacebisi yokusela utywala emva kokugqiba unyango kangangexesha elithile. Kufuneka wathi iziphumo ebezingalindelekanga lokusetyenziswa utywala ngexesha unyango kwenzeka kakhulu ngokukhawuleza, nokuphuhlisa kuphetshwa kakhulu utywala.

Iimpawu disulfiramopodobnyh ukusabela

Ngophuhliso yeziphumo ebezingalindelekanga ogulayo imvakalelo imfudumalo kunye anozizi umzimba ongentla indawo yobuso. Ukongeza, kuncitshiswa uxinzelelo, ukuphefumla nzima, kunyuke izinga intliziyo. Izigulane kufuneka imvakalelo yengxinano esifubeni, ukoyika. State ihamba iingcinga kuza ukufa, isicaphucaphu, ubuqhophololo. nengozi yokuba ukuphazamiseka kwenkqubo luvo. Ngenxa yokwanda izixa utywala kwandisa amandla kunye nobukhali disulfiramopodobnyh ngayo. Kwezinye iimeko, elo nxeba ukuwa - ukuhla elibukhali kwi xi kulahleka sezingqondweni.

Unyango kwezigulane butywala ezingapheliyo

Imbali ukusetyenziswa "Disulfiram" iziyobisi ukuze kupheliswe ukuxhomekeka etywaleni yaqala ubonwa enye umdla. Kwenye iifektri ngenxa imveliso iirubber iye yehla kakhulu ukusetyenziswa kwabasebenzi utywala. Ngexesha isifundo, kwaye kwafunyaniswa ukuba isizathu yinto disulfiram kwento nje isicelo ngexesha nokuveliswa amanqaku zerabha. Le kwafunyaniswa kwakhokelela ekubeni umchiza yaqala ukuba isetyenziselwe iinjongo zonyango. Kungekudala emva koko, iingcali waphawula ukuba disulfiramopodobnye indlela evusa inani amayeza. Amanye amachiza aye ityumbe ngokukhethekileyo otywala ezingapheliyo. Ngokomzekelo, oogqirha uyakukumisela lona lithetha "Trykhopol". Le ichiza yinxalenye yonyango oluntsokothileyo abanye oogqirha ukumisela namhlanje. Kucetyiswa iikhosi ethululwayo 250 mg ka-2 p. / Day. Uthomalaliso yenziwa kabini ngonyaka. Kwezinye iimeko, iyeza ebekiweyo ixesha elide - ukuya kutsho kwiinyanga eziliqela.

Elumnkisa xa uthatha iziyobisi ezithile

Abantu abo ungasivumeli ukuba ukuxhomekeka etywaleni, oogqirha sincoma kakhulu ngokuthatha nawaphi na amayeza kudityaniswe utywala. Kubaluleke ngokukodwa ukuba bagcine isilumkiso xa ezifumana unyango isibulala-zintsholongwane. Kufuneka kukhunjulwe ukuba ukusetyenziswa idibene kweziyobisi kunye ethanol, ukongeza kuphuhliso reactions disulfiramopodobnyh, kwandisa ingozi yokwenzakala kwesibindi sinxilisayo, sasiphikisana oluntsonkothileyo imisebenzi yalo ebaluleke kakhulu (ukuhluza kunye ubuthi). Ukongeza, oko konyusa ubunzulu side effects bandiqumbisayo mithi, iziyobisi ezichaphazela luvo kunye namanye amalungiselelo. metabolites ezingenabungozi, ezithi zenziwe indibanisela iziyobisi kunye notywala, bayakwazi ukutshintsha isenzo esithathwe yi-mali. Le nto yenza ukuba nemiphumela emibi kakhulu kwezinye iimeko ezikhokelela ekufeni.

Izinyathelo unyango, kuxhomekeke ukusetyenziswa kotywala

Kuba abantu abaxhomekeke etywaleni, iziyobisi ezahlukeneyo ziphuhliswe, inceda ubuncothule rhurha.

Iingcali khumbuza ukuba ukuthatha nawaphi na amayeza kufuneka kuvunyelwane kunye nogqirha wakho. Asingabo bonke otywala ngokuzithandela unyango. izigulane ezinjalo kufuneka anikwe uncedo lokuqala nasengqondweni. Umntu onesifo butywala, kufuneka lwaziswe zonyango ukuba. Xa umcimbi kufuneka ibe ngaphandle ulwazi lwakhe ukunika naziphi na iziyobisi ezibangela Ukwehluleka utywala! Oku "unyango" ayikwazi kuphela ukuba kuphumelele, kodwa ezimbi, yingozi kwezinye iimeko, imiphumo.