"Z-factor": ncomo, imiyalelo ukusetyenziswa, imiphumela emibi

Medicine "Z-factor" yemiyalezo uchaza njenge zintsholongwane bacteriostatic ngoweqela of macrolides, azalides. Eli chiza spectrum ezibanzi amanyathelo elwa. Indlela yomsebenzi ezinxulumene kwezithandani leeprothini kudibaniso kwizisele ngeentsholongwane, ngokwenjenjalo sehlise ukukhula nokukotshwa iintsholongwane. Zintsholongwane "Z-factor", ukubuyekeza ezigulane kunye neengcali ezithi HIV rhoqo, olusebenzayo ngokuchasene eziphilayo kwisebe extracellular ezimbi-Igram kunye Igram-HIV kwaye amanye anaerobic. amagciwane Okwa ekuqaleni zimelane ukuya medicament okanye ukufumana le ukuxhathisa ngexesha ukusebenzisa iziyobisi.

iipropati pharmacokinetic

component Active beziyobisi "Z-factor" yemiyalezo ebizwa azithromycin. It ako kakuhle emzimbeni abelwa ngokukhawuleza. Emva nedosi enye ye-milligrams 500 kuthetha bioavailability yi-37 ekhulwini, emva kweeyure ezimbini okanye ezintathu plasma idaliwe ukufumaneka liphezulu - 0.4 ngokweemiligremu ilitha nganye. Medicine "Z-factor" ingena inwebu yeseli kwaye ukuya kwindawo ziiphagocytes usuleleko, apho phambi arhente akhululwe. Le medicament idlula ngokulula gistogematicalkie imiqobo. In ancedisana iiseli uyondelelwano lwee- izihlandlo ezilishumi ukuya amahlanu ngaphezulu kunoko iqatshelwe plasma, ngexesha elifanayo umthombo usuleleko yi-avareji 24-34 ekhulwini ngalinye ngaphezulu kwizihlunu esempilweni. Kanye esibindini, ichiza demethylated, ngaleyo ndlela alahlekelwe umsebenzi. Emva kokufumana azithromycin kwi ngamayeza nokunyanga boxinzelelo bazondelele kule emzimbeni iintsuku ezintlanu-esixhenxe, okubangelwa emathunjini ubukhulu becala mba (50 epesenti) kunye nezintso (6 pesenti).

Ubungqina obubonakalayo buxela ukuba

A medicament ngokufanelekileyo izifo ezosulelayo kunye ukudumba okubangelwa amagciwane basengozini ichiza. Ngoko ke, lo medicament isetyenziswa "Z-" ngaphakathi sinus, sinusitis, tonsils, amajelo otitis, pharyngitis kunye nezinye izinto ezimbi Kwiphecana eliphezulu bokuphefumla phecana eliphezulu zemiphunga. Ukumisela amayeza kunye nezifo phecana ukungaphefumli: nephika, inyumoniya, kuquka ezo zibangelwa kwamagciwane Nedlac. ukusetyenziswa kweziyobisi "Z-factor" imiyalelo zokusetyenziswa olucetyiswayo zizifo ezithambileyo izihlunu, isikhumba: dermatoses, erysipelas, impetigo; usulelo lwe womchamo: cervicitis, urethritis.

release Form

Ichiza iveliswa ngokohlobo amacwecwe kunye njengezingxobo. Amacwecwe lenticular "-factor Z", lume, Bathiwe wambu iqokobhe ukukhanya epinki. Valium zahlanganiswa iipakethe ezintathu. Njengezingxobo zimhlophe, nzima, gelatin; imixholo - umxube ngumgubo kunye granules. Zahlanganiswa 6 okanye 10 kumadyunguza wekhadi.

isakhiwo

Xa tablet enye yinto esbnzyo - azithromycin (kwifomu dihydrate i) - ekhoyo xa kukho imali milligrams 500 philisi nganye yaye - 250 milligrams. Njengoko nokuxhasa udweliso ekwakhiweni kwezi tablets kusetyenziswa povidone, nemagnesium stearate, dihydrate calcium phosphate, isodiyam lauryl sulfate, crospovidone, talc, titanium dioxide, ebomvu acid idayi, hydroxypropylmethylcellulose, polysorbate. izinto Secondary eliquka njengezingxobo izinto umbona starch, isodiyam lauryl sulfate, imethyl parahydroxybenzoate, iswekile ubisi, acetic acid, laktopress, aerosil, nemagnesium stearate, povidone, titanium dioxide, gelatin, kunye propyl parahydroxybenzoate.

Iimpawu isicelo, idosi

Iyeza kufuneka athathwe ngomlomo kanye ngemini, iyure enye phambi kokuba izidlo okanye iiyure ezimbini emva. Lwezifo ze phecana yokuphefumla, amalungu aphezulu nokuphefumla, kwizihlunu ezithambileyo kunye nesikhumba amisele idosi yemihla ngemihla ye-500 mg, uthomalaliso waqhubeka kangangeentsuku ezintathu. Ikhosi konyango lwe migrans erythema oku kulandelayo: ngosuku lokuqala ukuthatha 1000 mg, ukususela yesibini ukuya ngomhla wesihlanu - mg 500 yonke imihla. In ayinzima cervicitis urethritis kuba mono- okanye uthathe 1000 mg beziyobisi. Izigulana ngokulinganisela ukusebenza kwezintso, kukho uhlengahlengiso idosi kufuneka.

imiphumela emibi. reviews

Of kukuvela reactions egwenxa emva ezithatha ichiza, "Z-factor" kukho iimpendulo ezahlukeneyo. Kaninzi, izigulane ezikhala norhudo, ubucaphucaphu, ukugabha, iintlungu esiswini, ukungacoleki kokutya, ukozela. Ezinye izigulane ingxelo iziphumo ebezingalindelekanga ezifana nesiyezi, amahlaba, intloko. In ezinqabileyo iimeko ukungahlaliseki, uvalo, ukuduma, iingxaki ukuva, umbono othile ivumba kunye nemvakalo. Imiyalelo yokusebenzisa phakathi kunokwenzeka iziphumo ebezingalindelekanga idwelisiwe yaye ezifana paresthesia, asthenia, ukudla, okwenziwa sisilonda pseudomembranous, necrosis hepatic, arrhythmia, ianemia, nephritis, neutropenia, හසුරුව isiphathi, arthralgia, photosensitivity, angioedema, hepatitis, ityhefu epidermal necrolysis, erythema multiforme . izigulane ngamnye ukubonisa "Z-factor" livela, uchuku namaxhala emva ngokusebenzisa ichiza. Ukuphononongwa, phakathi kwezinye izinto, iqulathe ulwazi malunga iziyobisi kungabangela utshintsho ngolwimi umbala, ukuqhina, irhashalala kunye ukurhawuzelela.

Izimo

Musa ukusebenzisa abantu medicament kunye hypersensitivity ukuya macrolides kunye kakuhle kakhulu umsebenzi zezintso / esibindini. Drug "Z-factor" kubantwana ukuya kwiminyaka elishumi akukho elimisiweyo. Kwakhona, musa ukuthatha amachiza kubafazi ngexesha zisanyisa, kunye dihydroergotamine kunye ergotamine, izigulane yelactose izivuka, a ukunyamezelana ngezemvelo galactose malabsorption glyukozogalaktoznoy. Amanyathelo emiselweyo amayeza abantu abaneengxaki mnene kakuhle kwezintso / hepatic, arrhythmia okanye sifuze kuso. Xa ukhulelwe, ichiza isetyenziswa kuphela xa inzuzo kulindeleke ukuba unina mkhulu umngcipheko ukuba uphuhliso olungekazalwa.

libanda

Utyatyazo, isicaphucaphu, ukugabha lisenokuba kwimeko lokufumana ngeedosi ngokugqithiseleyo yokulungiselela "Z-isici." Izimvo abantu engqinela inkangeleko yale uphawu njengelahleko ezindlebeni okwethutyana. Xa libanda, elawulwa unyango nomqondiso.

Unxibelelwano namanye amachiza

Asidi ukunciphisa nge-30 ekhulwini uyondelelwano lwee- azithromycin kwi-plasma, ngoko medicament "Z-factor" kufuneka athathwe iyure enye ubuncinane phambi okanye iiyure ezimbini emva kokuba ukusetyenziswa kwala machiza kunye nokutya. Yoxinaniso plasma didanosine, methylprednisolone, carbamazepine, rifabutin, xa esetyenziswa kunye, azithromycin ayiphazamiseki. Nangona kunjalo, asimele na ngaphandle ifuthe layo phezu uyondelelwano lwee- cimetidine, indinavir, triazolam, i-fluconazole, midazolam, efavirenz, trimethoprim. Ukuba ufuna ukusebenzisa i amayeza, "Z-factor" ngaxeshanye cyclosporine okanye digoxin, kuyimfuneko ukuba iliso igazi iplasma elidlulileyo, kwaye xa esetyenziswa kunye warfarin Kucetyiswa ukuba esweni ngenyameko ixesha prothrombin. Ulawulo ngaxeshanye terfenadine kunye azithromycin kunokubangela arrhythmia, ngokunjalo kwisithuba yokwandisa QT.

oyi

Ukuba isigulane balibala ukusela amayeza, kufuneka uthathe ithamo ephosiweyo ngokukhawuleza kangangoko kunokwenzeka, kwaye elandelayo - kudluliswe ngemini (iiyure ezingama-24). Xa unyango kunye azithromycin, kwakunye ekusetyenzisweni naluphi na unyango isibulala-zintsholongwane, kukho umngcipheko superinfection ukulawula, kuquka ezinzwaneni. Kuba unyango tonsils kunye pharyngitis okubangelwa iStreptococcus neArcanobacterium, kunye nokuthintela samathambo ngokuqhelekileyo emiselweyo penicillin. Kufuneka kuqatshelwe ukuba azithromycin iyasebenza kusulelo streptococcal, kodwa akukho ezifanelekileyo nokuthintela samathambo.

"Z-factor" iziyobisi. analogs

Ngoko nangoko ndiya bathi kuthetha "Z-factor" ayikho siyobisi yokuqala. Ingaba ichiza yangaphakathi generic "Sumamed", eyenziwe ziingcali yenkampani eyenza imithi "Pliva" Croatian ngo-1980. Ukuza kuthi ga ngoku, efumanekileyo nucleoside ezininzi "Sumamed": ukongeza ichiza "Z-factor", ziquka loo mithi "Azitroks", "Hemomitsin", "Azitsid", "Sumatrolid soljutab", "Zitrolid", " azivok "," safocid "," Azitral "," Sumamoks "," Sumametsin "kunye nabanye. Ngoko ke kukho umahluko kukuba ukwamkela: generic "Z-factor" okanye "Sumamed", nto leyo siyobisi yokuqala? Impendulo engagungqiyo lo mbuzo akukho. Ngokutsho iimpawu amayeza kula machiza ziyafana, umahluko kuphela kumenzi kunye nexabiso. Noko ke, izigulane ezininzi bafumanisa ukuba analog ngokwenkcazo kubi ngaphezu yokuqala, kuba xa umenzi wayo nje kuqhutywa izifundo kunye yolingo lwezonyango. Xa unikel 'ingqalelo ngexabiso, kungcono ukuthenga njengendlela "Z-factor": ixabiso njengezingxobo ezintandathu umlinganiselo 171-187 engange, ngoxa njengezingxobo ezintandathu "Sumamed" kufuneka uhlawule 448-530 engange.

Imibono ezigulane malunga ichiza "Z-factor"

Izimvo zabantu malunga amayeza buhle. Inkoliso abo ukhe wasebenzisa iziyobisi, phakathi zalo eziluncedo qaphela ukusebenza eliphezulu ngexabiso eliphantsi kakhulu. Izigulane zibonisa ukuba ichiza ingakumbi kunceda nge angina. Uziva ngosuku olulandelayo emva kokufumana kweemali ngcono kakhulu, kuba umqala obuhlungu, ukukhohlela, lihlwili kwamalunga. Kwakhona amayeza ngempumelelo nokuphelisa sinusitis: ngosuku lwesibini lonyango ephelisa ngeempumlo ukuxinana, ayeke yintloko. Okwangoku, zonke ncomo mihle. Abanye abantu bayathetha uphuhliso ukuphazamiseka enamandla zokwetyisa izigulane abafumana lithetha "Z-isici." izigulane ngabanye ingxelo ukuba emva kokuthatha iipilisi / iipilisi sungule ku va embi: kwakukho iimpawu ezifana uvalo, ukuphelelwa umoya, iyangongoza intliziyo, ixhala, uloyiko. Kwiimeko ezinjalo, ichiza kufuneka lwayekiswa yaye bafune uncedo lobungcali.

ulwazi olongezelelweyo

Medicine "Z-ngumba" of Pharmacy kagqirha zonyango. Ukukwazi ukuqhuba nokulungiselela iindlela kunye nezithuthi lungenasiphumo. lokugcinwa ukususela nokukhululwa kwiminyaka emibini, amayeza kufuneka igcinwe kude yabantwana ekhuselweyo elangeni kwiqondo elingadluliyo 25 degrees Celsius.