Umhlaza pancreatic

Umhlaza pancreatic is a neoplasm amabi, wabumba iiseli uyila pancreas. Uhlobo ziqhelekileyo zomhlaza, nto leyo ebangela ukuba ukuya kwi-95% yazo zonke iimeko yalo Ithumba i adenocarcinoma, leyo iphuhlise ngaphakathi component exocrine pancreas. Adenocarcinoma - ithumba echaphazela izihlunu glandular umzimba. Noko ke, asingabo bonke amatyala lomhlaza pancreatic - nje adenocarcinoma enjalo. Kwezinye iimeko, nethumba ikhulela iiseli ekuthiwa njalo-esigcwele, ngoko lichazwa njenge ithumba neuroendocrine. Lweempawu ezibangela urhano umhlaza zixhomekeke indawo ye ithumba, ubukhulu balo kunye uhlobo amalaphu, umfanekiso walo. Ngokubanzi, iimpawu umhlaza pancreatic ziquka iintlungu esiswini, iintlungu komhlana asezantsi, kwaye ukuba nethumba Oluma ye bile duct, senyongo. Ukongeza, kungakhona ebalulekileyo ukwehla kobunzima, ukurhawuzelela, ukudakumba, etsolo vein thrombophlebitis (uphawu Trousseau kaThixo), uphawu Courvoisier kunye nabanye abaninzi.

Xa nokubeka imihlaza esabulala umhlaza pancreatic ngokuzithemba unesitifiketi obekekileyo unobangela yesine phambili yokufa phakathi kwamadoda nabafazi, nokuba ngumtyholwa 6% yabo bonke abafayo ngumhlaza. Bamalunga nama-ezintathu kwezine zonke zomhlaza pancreatic zikhula entloko okanye emqaleni umhlaza, 15 ukuya ku-20 ekhulwini yamathumba asakhasayo emzimbeni nobubovu ngqo, yaye ezinye-5 ukuya ku-10 ekhulwini umsila wayo izakuvela.

Unyango womhlaza pancreatic kunzima ngokwaneleyo, ngoko njani ukuhlola le ithumba kwi isaqala kakhulu, umsebenzi onzima kakhulu. Ngaphezu koko, Ngokwezibalo, ngaphezu kwesiqingatha zonke izigulane ngexesha uphethwe "umhlaza pancreatic" abathwali kwakukho nangezilonda kuwenza, yaye ngowama-26 ekhulwini sisilonda esidumbileyoesingaphakathi kwaphawuleka kwiindawo nkovu yengingqi. Ukuqhubeka isihlobo yezigulane kunyaka wokuqala emva kokuxilongwa, "umhlaza pancreatic" yi ekhulwini 26 kuphela. Noko ke, efana umlinganiselo seminyaka emihlanu asezantsi nangona nje nje 6%.

Kufuneka kuqatshelwe ukuba zonke yamathumba pancreatic ezi adenocarcinomas 80% wobisi epithelium. 2 kuphela ekhulwini yamathumba zepancreas exocrine ingozi.

iintlobo Ngaphantsi eziqhelekileyo iintlobo zomhlaza histological pancreatic ziquka yamathumba ezifana cell carcinoma omkhulu, glandular, carcinomas cell carcinoma, mikroglandulyarnaya adenocarcinoma, carcinoma mucoid, cystadenocarcinoma, carcinoma papillary esinganyangekiyo, cystadenocarcinoma acinar, atsinoznokletochnaya cystadenocarcinoma. kunqabile kakhulu kuyenzeka ukuba isigulane eziphuhliswe ithumba pancreatic kwizicwili. Uhlobo ziqhelekileyo zomhlaza yeyona lymphoma pancreas.

Ngokuqhelekileyo, le Ukudlulela yokuqala kweziphumo umhlaza pancreatic kwiindawo nkovu yengingqi, isibindi uze ngaphantsi njalo lung. Ukongeza, nethumba zikhula ngqo amalungu, leyo abekwe kwi peritoneum kufuphi nesosredstvenno nobubovu, ngamanye amazwi ukuba isisu, duodenum kunye colon. Ngaphezu koko, umhlaza pancreatic ukuze iyakhula peritoneally nawuphi na umgangatho ibekwe kwisisu. Ngenxa yoko, ukuze aphuhlise ascites (unegalimoya), kwaye ke umqondiso kakhulu, ezimnyama kunye embi kakhulu. Umhlaza pancreatic nga iyakhula nolusu kwaye eziya wabonakaliswa ngokohlobo maqhuqhuva ezibuhlungu. Kuyo yonke le nto loo yamathumba kunqabile ukunika metastases ukuya ithambo.