Prokinetics: uluhlu kwisizukulwana esitsha kwamachiza

Okwangoku, ebangela utyelelo noogqirha - ezi iingxaki kwisiqwenga zesisu. Phantse ngalinye kubo iphawulwa yaphula umsebenzi motor. Noko ke, ukuze ibonakale njengoba iimpawu ndandingenampilo sinxulumana kwinkqubo yokwetyisa. Kuyo nayiphi na imeko, Asinakuyenza ngaphandle prokinetics iziyobisi qela. Uluhlu iziyobisi kweli qela ayikho sikhokelo ezingqongqo. Ngoko ke, wonke ugqirha ukhetha ngamalungiselelo abo, kuxhomekeka sifo. Emva koko, thatha sihlolisise, yintoni prokinetics, uluhlu lweemveliso-isizukulwana esitsha, kakhulu ngokufuthi esetyenziselwa unyango.

Prokinetics: iimpawu ngokubanzi

Iziyobisi Ndiyijike umsebenzi lwemoto le iphecana wamathumbu nokukhawulezisa sendleleni lokutya kunye nenkqubo bakukhuphela, eyakho nje kweli qela.

Njengoko kukhankanyiwe ngasentla, ayisekho uluhlu olunye la mayeza kwiincwadi Gastroenterology. Wonke ugqirha apha iquka uluhlu iziyobisi. Ezi ziquka iziyobisi, kunye namanye amaqela, ezifana antiemetics, antidiarrheals, yaye ezinye iintsholongwane macrolide, peptides hormone. Ukuze uqale ufumanise ukuba yintoni na inyathelo amayeza eli qela iziyobisi.

isenzo prokinetic

Okokuqala bonke baya kukhuthaza motility ye phecana wokudla, kwakunye ilifa ukusebenza antiemetic. Ezo amalungiselelo ukukhawulezisa indlela yokulahla isisu kunye namathumbu, ukuphucula kwezihlunu wokugaya, zinqanda pyloric kunye reflux nowomqala. Prokinetics iphathwa njenge monotherapy okanye zidityaniswe namanye amachiza. Zingakotshwa zohlulwa ngokwendidi eziliqela ngokwimiselo amanyathelo.

iintlobo prokinetic

Umgaqo ukusebenza kwinxalenye ezahlukeneyo iphecana zesisu yahlukile iziyobisi ezifana prokinetics. Uluhlu amachiza kufuneka lungohlulwa lube zezi ntlobo zilandelayo:

1. blocker of receptor dopamine:

• 1st ukukhetha kunye isizukulwana we2.
• Nonselective.

2. abamelene of receptors-5-HT3.

3. agonists of receptors-5-HT3.

Kwaye ngoku iinkcukacha ezingakumbi malunga kula maqela.

blocker Dopamine receptor

Iziyobisi kweli qela zahlulwe zibe uyakhetha and non-uyakhetha. effect wabo ukuba zisenza imoto umsebenzi esiswini ilifa iipropati antiemetic. Yintoni prokinetic? uluhlu iziyobisi na ngolu hlobo lulandelayo:

• "Metoclopramide".
• "Bromopride".
• "Domperidone".
• "Dimetpramid".

Le esisebenza eziphambili - metoclopramide, walisebenzisa ixesha elide. Eli nyathelo ngolu hlobo lulandelayo:

• Ukwanda umsebenzi we sphincter esezantsi esophageal.
• Ekukhawuleziseni yokulahla esiswini.
• Ukwanda kwesantya intshukumo ukutya ngokusebenzisa emathunjini amancinci emathunjini.

Noko ke, iziyobisi ezingekho-uyakhetha engabangela ukuba nemiphumela emibi kakhulu.

Kukho isizukulwana ezaziwayo-kakuhle yokuqala prokinetics. Uluhlu amachiza:

• "Reglan".

• "Raglan".
• "Perinorm".
• "Tseruglan".

Enye kubakho iingxaki kukwazi ukwenza imiqondiso kunye neempawu zesifo Parkinson xa abadala kunye nabantwana dyskinetic syndrome, ukuphazamiseka exesheni kwabasetyhini.

Ziziyobisi-generation yesibini uyakhetha iziyobisi kunye domperidone kweziyobisi esebenzayo. La machiza musa baxabane kakhulu ezibi, kodwa kungenzeka ngaphezulu:

• Ubuthongo.
• Ubuthathaka.
• Ixhala.
• Intloko ebuhlungu.

Kungenxa yesi sizathu ukuba amachiza kunye domperidone into esebenzayo - prokinetics kakhulu. Uluhlu amachiza:

1. "Motilium".
2. "Domidon".
3. "Motinorm".
4. "Motoriks".
5. "Gastropom".

Isizukulwana esitsha prokinetics

Ngu kwisizukulwana ukukhetha lesibini arhente prokinetic ziquka iziyobisi itopride hydrochloride esebenzayo. imali ezinjalo wazuza ingqalelo Bulelani isiphumo ezibalaseleyo zonyango kunye nokungabikho ziziphumo ebezingalindelekanga, nkqu kunye nokusetyenziswa ixesha elide. Amaninzi, oogqirha amisele:

• "Itomed".
• "Ganatom".
• "Itopride."

Oku kunokucaciswa iimpawu ezintle hydrochloride itopride:

1. Ukuphuculwa motor kunye ngobungxamo umsebenzi esiswini.
2. umsebenzi Ukwandisa lwesinye inyongo.
3. Yandisa né kunye nethoni kwizihlunu ezincinane enkulu emathunjini.
4. Ukukhuthaza nokuphelisa of reflux duodenal.

prokinetics zesisu

Ezi ziquka prokinetics - agonists ze receptors-5-HT3. Le into esebenzayo - tegaserod. Oku kunempembelelo entle motor nokufuduswa umsebenzi ikholoni kunye emathunjini amancinci. Oku kunegalelo kuqheleke esitulweni, kunciphisa iimpawu namathumbu nochuku.

Oku akuthethi ukuba ukwanda koxinzelelo alunasiphumo kwi nemithambo yegazi. Nangona kunjalo, kukho inani elaneleyo yeziphumo ebezingalindelekanga. Ngamaxesha amaninzi kwandisa amathuba okuba nestroke, sifuba angina, uhlaselo anginal. Okwangoku, iziyobisi kunye into esebenzayo isuswe imveliso kwilizwe lethu yaye kwamanye amazwe kwizifundo zokuqhubela phambili. Oku kuquka prokinetics zilandelayo (uluhlu iziyobisi):

• "Tegaserod."
• "Zelmak".
• "Fractal".

Abamelene 5-NTZ receptor

Prokinetics eli qela efanelekileyo ukulungiselela unyango kunye nothintelo isicaphucaphu nokugabha. Xa yokwamkela yabo kunciphisa ixesha yokuhlala kokutya esiswini, ukwanda isantya sendleleni ukutya ngokusebenzisa amathumbu, normalizes nethoni yelo ikholoni.

release acetylcholine khona, nokuphucuka umsebenzi lwemoto le phecana zesisu. Okwangoku kwemfuno enkulu phakathi izigulane kunye amagqirha namhlanje prokinetics. Uluhlu amachiza isizukulwana esitsha:

• "Tropisetron."
• "Osetron".
• "Ondansetron".
• "Silansetron".

Kufuneka kuqatshelwe ukuba bachasene ka-5-NTZ receptors abanayo nempembelelo enyangayo, ukuba ukuphalaza okubangelwa apomorphine.

Ezi Amachiza ukunyamezeleka kakuhle, nangona kukho uneziphumo ebezingalindelekanga:

• Intloko ebuhlungu.
• Nokuqunjelwa.
• Nayo ukugungxula.
• komzimba.

UNYE umdibanise kula machiza - abanayo i okulalisa, musa basebenzisane namanye amayeza musa ukuba utshintsho yonyango ukuba musa kungqubana umsebenzi motor.

Zeziphi izifo abeke

Njengoko kuchaziwe ngentla, prokinetics esetyenziswa monotherapy okanye ngokusebenzisana antibiotics. Oogqirha uyazi ukuba kukho izifo apho ukuqeshwa amaxesha prokinetic eziliqela kwandisa ukusebenza konyango. Kweli qela zezi:

1. Izifo ometyiso umsebenzi motor kakuhle.
2. Gastroezofagelnuyu isifo reflux.
3. Esuswini (isilonda duodenal).
4. gastroparesis Idiopathic.
5. Ukubuyisa.
6. Nokuqunjelwa.
7. Ocaphuka msinya wamathumbu Syndrome.
8. gastroparesis seswekile.
9. Flatulence.
10. Isicaphucaphu okubangelwa unyango ngamachiza kunye radiation, usuleleko, ukuphazamiseka esebenza, ukungondleki.
11. Ukuqunjelwa.
12. zeDyskinesia Biliary.

Ngubani na ukuthatha

Kuba amalungiselelo prokinetics kukho contra-zikhombisa:

• Hypersensitivity ukuya into esebenzayo.
• Esiswini okanye ukopha emathunjini.
• Perforation esiswini okanye emathunjini.
• Ileus.
• sisibindi, iingxaki zezintso.

Akunconywa ukwamkelwa, ukuba lo msebenzi ufuna ukujolisa ngakumbi ingqondo, kwakunye nabo angenise imoto. Ngokukhathalela amisele prokinetics abadala.

oomama abakhulelweyo nabongi

A amagama ambalwa ndifuna ukuthi malunga iziyobisi ngexesha lokukhulelwa. Uphononongo lubonise ukuba prokinetics anento ukungena kwi ubisi lwebele, ngoko ke ixesha unyango ngala amayeza kufuneka abaqhubeki nokuncancisa.

Xa ezintathu zokuqala zokukhulelwa kwabasetyhini kudla ukugabha isicaphucaphu. Kulo mzekelo, unganika le mithi prokinetics. Uluhlu lweemveliso abasetyhini abakhulelweyo Oku kuya kubandakanya kuphela ezo nto isongela ubomi umfazi omithiyo olungekazalwa.

Ingenelo ngayo ngaphezulu yonke imingcipheko kunokwenzeka. Prokinetics metoklopromid ne arhente esebenzayo zingasetyenziswa kweli qela kuphela kagqirha. Xa trimesters kamva zokukhulelwa prokinetiki Azityunjwa.

Okwangoku, eli qela iziyobisi ngexesha lokukhulelwa akukho kuboniswe ngenxa yenani elikhulu yeziphumo ebezingalindelekanga.

Prokinetics abantwana

Prokinetics isicelo isithako metoclopramide ebonakalayo abantwana kufuneka sobenno isilumkiso, njengoko kukho umngcipheko wokuba isenzeko dyskinetic syndrome. Oku emiselweyo kuxhomekeke ubunzima yomntwana.

Ukuba wezingane amisele prokinetics, "Motilium" lidla ziqukwe kuluhlu. Yena ukunyamezeleka kakuhle kwaye kakhulu ingxelo entle. Kodwa linokukwenziwa kwezinye prokinetics. Uluhlu lwamachiza abantwana anokuqulatha igama zilandelayo kodwa:

• "Domperidone".
• "Metoklopromid".

Kubalulekile ukuphawula ukuba abantwana abangaphantsi kweminyaka emi-5 elungiswa "Motilium" ekucetyiswa ukuba zisetyenziswe ngohlobo ukunqunyanyiswa. Ichiza emiselweyo kuxhomekeke ubunzima umntwana, izinga ml 2.5 10 kg bodyweight nganye. Ukuba kuyimfuneko, ithamo unako wande, kodwa kuphela abantwana abadala ngaphezu konyaka omnye. Kwakhona, ichiza yakhululwa uhlobo iilozenji.

abantwana Prokinetics emiselwe ukuba umntwana wakho:

• Ukubuyisa.
• Isicaphucaphu.
• Esophagitis.
• ukugaywa Slow.
• iimpawu Dyspeptic.
• regurgitation rhoqo.
• Gastro-esophageal reflux.
• Dysmotility ye phecana zesisu.

Kufuneka kuqatshelwe ukuba ziphuhliswe kwezi nyanga yokuqala yobomi omzimba womntwana kunye nemisebenzi yayo yonke hayi kakhulu, kangangokuba zonke iziyobisi kufuneka athathwe phantsi kweliso ngqongqo nokulawulwa kugqirha. Kwimeko prokinetics libanda kunokubangela iziphumo ebezingalindelekanga luvo kwiintsana kunye nabantwana abancinane.

athandwa kakhulu phakathi abazali iintsana isebenzisa ukulungiselela esintu, nto leyo iphucula yokwetyiswa kunciphisa flatulence. Oku lugxile ngokusekelwe iziqhamo fennel "Plantex".

Iyafuna esithi amagama ambalwa malunga prokinetic izityalo.

abancedi zemvelo

Ngoko ihlabathi ukuba unyango nasiphi na isifo ingafumaneka kwezinye izityalo, kufuneka nje ukwazi - koko. Ngoko ke, lo prokinetics esaziwa, leyo ukuvuselela umsebenzi phecana motor zesisu. Nazi ezinye zazo:

• Fennel.
• Chamomile.
• Sambucus nigra.
• Idile.
• Oregano.
• Motherwort.
• Edandelion.
• Melissa.
• Cudweed.
• Ngeplantain.
• olhovidnaya sihlahla.

Uluhlu lwezityalo ukunceda ukuphucula motility ye phecana zesisu, iquka inani elikhulu kwezinye iintlobo izihluma. Kufuneka kwakhona Makusoloko kukhunjulwa ukuba ezinye iziqhamo kunye nemifuno neziphumo ezifanayo:

• Rutabaga.
• Melon.
• Khaphetshu.
• Iminqathe.
• Beetroot.
• Ithanga.
• Cranberries.
• Iidiliya.

Iipropati prokinetic azibonakali kakuhle kakhulu kule imifuno, xa ukuba ubasuse incindi balungiselela entsha.

Kubalulekile ukuphawula ukuba indawo izifo amachiza sisityalo ngamaxesha exacerbation kwaye ngaphandle kokubonisana ugqirha.

imiphumela emibi

Kubaluleke kakhulu ukuba isizukulwana esitsha prokinetics zineziphumo ebezingalindelekanga ezimbalwa kakhulu iziyobisi-sizukulwana sokuqala kunye isithako metoclopramide esebenzayo. Kunjalo, yaye inkoliso namayeza amatsha kukho iziphumo ezingalindelekanga:

• Intloko ebuhlungu.
• Ucaphuka.
• umlomo owomileyo, linxano.
• Spasm of izihlunu agudileyo phecana zesisu.
• Izigxala, irhashalala, ukurhawuzelela.
• Hyperprolactinemia.
• Abasafunda ukuhamba ngazo iimpawu extrapyramidal.

Emva ukupheliswa iziphumo ebezingalindelekanga echiza ngokupheleleyo.

Ukuba ugqirha ubeka prokinetic, uluhlu iziyobisi kungaquka iziyobisi ezininzi amagama ahlukeneyo kodwa into enye esebenzayo. Kulo mzekelo iziphumo ebezingalindelekanga uya kuba njalo.

Iimpawu lokusebenzisa prokinetic

ngenyameko kakhulu kufuneka ufakwe abantu prokinetic kunye ukusilela wesibindi nezintso umsebenzi kakuhle. izigulane anjalo kufuneka abe phantsi kweliso elibukhali likagqirha olungqongqo.

Nokusebenzisa ixesha elide izigulane prokinetic kufuneka uye kugqirha wakho rhoqo. Kunye prokinetics ukusebenzisa ngenyameko kubantwana abaselula, ingakumbi ukuya kunyaka omnye.

Ngokuqaphela kuyimfuneko ukumisela iziyobisi kweli qela izigulane abalupheleyo.

Xa unyango lwe prokinetic kufuneka benze umsebenzi kufuna ingqalelo impendulo ngokukhawuleza.

Ngaphambi kokuba kufuneka kusoloko ubonane nogqirha. Kulo kuxhomekeke impilo yakho. Asinto amayeza kuyimfuneko ukuba indawo zakhona analogu ngaphandle kuqala kokubonisana ugqirha wakho.