Lithetha "simvastatin" umyalelo kwi isicelo ichaza neziyobisi hypolipidemic bobabo kwiqela, kunye statins ke inhibitors lohlobo HMG-reductase awula. Le medicament i prodrug, ekubeni isakhiwo sayo ekhoyo kwi ivaliwe, ekuthiwa-ring lactone leyo, emva kokungena umzimba womuntu hydrolyzed. Ichiza "Simvastatin" (Imiyalelo kwi isicelo kwalo lujolisa) inceda ukwehlisa amanqanaba igazi triglycerides kunye lipoprotein kunye cholesterol iyonke. Ngelo xesha ukuphuhlisa isiphumo enyangayo luqala emva malunga ezilishumi okanye iintsuku ezilishumi elinesine ukususela ekuqaleni ukusetyenziswa, kwaye kangangoko kolu yesine ukuya kwiveki yesithandathu.
Iyeza senziwa becala ngokohlobo amacwecwe ngeenxa biconvex. Ukubunjwa pellet nganye njengoko yinto ephambili esebenzayo iye milligrams amabini simvastatin. Olongezelelweyo macandelo lactose, polyvinylpyrrolidone, calcium stearate, citric acid, hypromellose, microcrystalline kwincindi, hydroxyanisole butylated, ascorbic acid, umbona starch, titanium dioxide, talc kunye Macrogol 4000.
Ukumisela lipid-yandisa iziyobisi "Simvastatin" yemiyalezo ucebisa, umzekelo, ukunyanga abantu abane hypercholesterolemia lokuqala. Noko ke, ukusebenzisa isixhobo kule meko kuyimfuneko kuphela xa ukudla. "Simvastatin" ichiza kwakhona efanele entle kakhulu kuba unyango lwe hypercholesterolemia zidityanisiwe. Ziveza kwaye zibandakanya izifo ezifana hypertriglyceridemia.
Thatha ezi tablets akuvumelekanga ngokungqongqo kubantu bathwaxwa iintlobo kakhulu ukuphazamiseka wesibindi insufficiency enkulu sezintso. Ukuba hypersensitive ukuya simvastatin okanye nayiphi na amacandelo abangabancedani iingcali ezifana yaleza ukuba ayeke ukuthatha "Simvastatin" lipid-lisibekele iziyobisi. Imiyalelo yokusebenzisa kufuneka unikeze ichiza kwizigulana abaye bengekafiki kwiminyaka elishumi elinesibhozo ubudala, abasetyhini abakhulelweyo kunye noomama abaselula nokuncancisa. Ngononophelo olukhulu kufuneka asebenzise ezi izigulane iipilisi abanesifo sesibindi, hypotension okanye ukuxhuzula. Xa utywala ezingapheliyo kunye nesifo kakhulu sezintso uthathe amayeza "Simvastatin" kufuneka ibe kuphela phantsi kweliso zonyango. Ukongeza, uluhlu Izimo isalamane ziquka wande nokwehla kwezihlunu skeletal.
Njengokuba kude njengoko iziphumo ebezingalindelekanga kunokwenzeka ukuba abe nomsindo ukusebenzisa iziyobisi "Simvastatin", into yokuqala apha kuyimfuneko kubabela elo umngcipheko pancreatitis, peripheral neuropathy, hypotension, myopathy, volchanochnopodobnogo syndrome, rhabdomyolysis kunye thrombocytopenia. Ukongeza, ukuxhuzula Inokwenzeka, isiyezi, flatulence, ukungabi namdla, angioedema, irhashalala, ukuhlisa, urticaria, eosinophilia, photosensitivity, vasculitis, ifiva, paresthesia kwezihlunu, alopecia, kunye nezinye.