Hormone testosterone kwaye umsebenzi wayo emzimbeni womntu

Xa abantu, kukho indlela ezimbini ezisisiseko ngolawulo amalungu kunye neenkqubo: i Wayesoyika humoral. Eyokuqala kwezi ikhutshwa phandle, enkosi innervation amaninzi amalungu, namadlala, imithambo yegazi lwangaphakathi kunye nezihlunu kunye nemisipha.

Indlela yesibini kungenxa amanyathelo ihomoni elikude apho ziveliswa kwamadlala yonyango, ize ke idluliselwe kwi kwemithambo yegazi kwi zomzimba okanye target omzimba. Ngoko ke, lo testosterone hormone, lo androgen inqununu, iveliswa ngezixa ezincinane yi neuron adrenal, naphezu kukuvela ukufikisa yamakhwenkwe uqalisa ngenkuthalo ziveliswa amatyhalarha, ngoko ke excretory imibhobho le ndlala akhululwayo egazini kunye Okunye nefuthe kwinkqubo musculoskeletal, kwaye kwakhona yokucolwa esibindini. Ngokutsho kumgaqo ingxelo testosterone nako ukulawula ukuveliswa kwezinye hormone (as in ababhinqileyo kunye nomzimba oyindoda).

umsebenzi testosterone

amanqanaba testosterone ngabantu, Kakade ke, ngaphezulu kakhulu kumgangatho kwabasetyhini, ngokuba emzimbeni iinkunzi lenza imisebenzi ngakumbi: xa ufikisa emakhwenkweni phantsi kwempembelelo wakhe, ukuyilwa ebizwa ngokuba iimpawu eziziisekondari ngokwesondo, oko kukuthi, ulwandiso "ngokuqhekezwa 'izwi ibhanti igxalaba xa kuthelekiswa isinqe, ukwandisa izihlunu ubunzima kunye ukugangatheka bone ekukhuleni gametes kwi gonads.

Ngabantu abadala, naye kunegalelo kulondolozo iintshukumo zesondo, oko kukuthi, inkanuko yesini, amandla kunye yakha ukuziphatha ngokwesondo psychophysiological. Le testosterone hormone lukhutshwe kwabasetyhini: kwi neuron adrenal, amaqanda kunye ukuguquka estrogen. Yena onesiphumo inhibitory kwi nokwanda kwe zoboya ovarian kwaye ilawula ukuveliswa estradiol kunye estrone nge esqwini hypothalamic-yebhinqa-adrenal. Xa hypersecretion kwabafazi bakhe okanye ulawulo eyenziweyo iziyobisi eziqulathe hormone (steroids ezininzi steroid), masculinization kwabasetyhini esivelayo, esizibonakalisa nzulu ilizwi, ukwanda iinwele umzimba, uphuhliso kwezihlunu kunye nokuziphatha ndlongo.

Ulawulo secretion of testosterone

Kukho iindlela ezininzi ezichaphazela izinga testosterone. UNorma namadoda akhe 11-33 nmol / ilitha, kunye nabafazi - kuphela 0,24-2,7. Kulo mzekelo, i testosterone hormone kwi zinegazi amaqhezu amabini: free wayibhinqa ukuba ukuthutha iiproteni ezinjengealbumin kunye globulin ethile ekwaziyo ziyabophelela hormone ngesondo (SHBG). Nangona kunjalo, umsebenzi begazi ubonisa mahala (2% yabo bebonke) kuphela testosterone bekhonkxiwe albumin. Emva kweminyaka 30-35 kumadoda le testosterone hormone njengoko bioavailability wayo, kwakunye iqhezu lilonke, bakholisa ukunciphisa ngesilinganiso ka-2-3% / ngonyaka, kwaye ebudaleni inqanaba testosterone esebenzayo mazincitshiswe amaxa-5 (uthelekisa kulutsha) kwaye lilonke - amaxesha 2.5. Ngokutsho kwezinye iingxelo, oku nje ukuhla kancinane secretion yayo, kodwa yandisa njengesibophelelo kwi SHBG, iqhezu ngaloo bioavailable ingasebenzi.