"Idrinol": imiyalelo yokusetyenziswa. Iingxelo, amaxabiso, inkcazo yokulungiselela

Ziziphi iimpawu zesilwanyana "i-Idrinol"? Izikhokelo zokusetyenziswa kunye neempawu ze-pharmacological zesi sixhobo ziya kuboniswa kweli nqaku. Kwakhona siya kukuxelela malunga nefom ekhutshwe ngayo iyeza, zingaphi iindleko, yintoni imiphumo emibi evela emva kokusetyenziswa kwayo, nokuba kukho ukuchasene, njl njl.

Ukubunjwa kwemveliso, ifomu yayo, inkcazo kunye nokupakishwa

Ziyiphi indlela abavelisa ngayo i-Idrinol? Umyalelo wokusetyenziswa usisichazela ukuba le nkunkuma ifumaneka ukuthengiswa ngendlela yesisombululo esenzelwe i-parabulbar kunye nokulawulwa kwe-intravenous.

Amachiza akwiyo mbuzo ngumbane ongenakubala obala. Isithako saso esisebenzayo si-meldonia dihydrate. Amanzi acwecwe asetyenziswa njengomncedisi.

Isisombululo sonyango sithengiswa kuma-ampoules (1 ml), ezifakwe kwiipakethi zeseli yeplastiki (iziqwenga ezi-5 ngamnye), kwaye zibe ziipakethi zekhadibhodi.

Iziyobisi zeFamaa

Yintoni into efana ne-Idrinol? Umyalelo wokusetyenziswa uthi i-substance esebenzayo (meldonium) isalathisi esakhiweyo se-gamma-butyrobetaine, oko kukuthi, into ekhoyo kuyo yonke iseli yomzimba womntu.

I-Meldonium inako ukukhusela i-gamma-butyrobetaine i-hydroxy genase, ukunciphisa ukuhlanganiswa kwe-carnitine, izithuthi zothutho zamacidi (ikhefu elide) ngokusebenzisa i-membranes, kunye nokuthintela ukuqokelela kwama-acids anoxidized acids, okuyi-derivatives ye-acylcoenzyme A kunye ne-acylcarnicin.

Umgaqo wokusebenza

Iyeza le-Idranol lichaphazela njani umzimba womntu? Imiyalelo yokusetyenziswa iqulethe ulwazi oluneenkcenkcesho ezinjenge-ischemia, isilwanyana esibuzwayo sinako ukulinganisela iinkqubo zonikezelo lwe-oksijini, ukusetyenziswa kwayo kwiseli, kunye nokukhusela ukuphazamiseka kwezothutho lwe-ATP. Ngaloo nto, isichengululo senza i-glycolysis, eqhubeka ngaphandle kokusetyenziswa kwe-O ₂ . Emva kokunciphisa i-carnitine, i-gamma-butyrobetaine iqala ukuhlanganiswa, enefuthe le-vasodilating.

Umgaqo wesigqirha unquma imiphumo yezolimo: ukuhla kweempawu zenyama kunye nengqondo, ukunyuka okuphawulekayo kokusebenza kakuhle, ukusetyenziswa kwe-immunity and tissues immunity.

Kufuneka kwakhona kuqatshelwe ukuba le nyilisi inomphumo we-cardioprotective. Ngomonakalo we-myocardial umonakalo (i-acute), uyakwazi ukunciphisa ukubunjwa kweendawo ze-necrosis, kunye nokunciphisa ixesha lokuvuselela. Ngexesha lokuhluleka kwentliziyo, isichengisiso sandisa ukunyamezela ukunyameka komzimba, kuphucula ukuthengiswa kwemvumelwano ye-myocardial kunye nokunciphisa ukuphindwa kwamatye. Ngenxa yokuphazamiseka okungapheliyo kunye nentsholongwane ye-cerebral circulation of nature ischemic, isicatshulwa sikwazi ukuphucula ukujikeleza kwegazi (kubandakanywa kwindawo ye-ischemia). Kufuneka kwakhona kuqaphele ukuba i-ejenti echaphazelekayo iyasebenza kakhulu kwimeko ye-pathologies ye-vascular ye- fundus. Ukongezelela, eli liyeza ngokukhawuleza liphelisa ukungaqhelekanga kumsebenzi we-system ye-nervous kwizigulane ezinexilongwane elingapheliyo (ngokukodwa ngexesha lokuzilahla).

Pharmacokinetics yonyango

Ubungakanani bokuba u-Idrinol uthatha ixesha elide? Imiyalelo yokusetyenziswa, ukuphononongwa kwabasemasimini kuyazisa izigulane ukuba ukuxinwa okuphezulu kwesi sichiza egazini kufumaneka ngokukhawuleza emva kokulawula. Emzimbeni womntu, ulungelelaniswa kunye nokwakhiwa kwezimbini ezinkulu ze-metabolites. Zifumene ngeendlela zeentso. Ubomi besiqingatha-sonyango malunga neeyure ezingama-4-6.

Iinkcazo

Amachiza, kwi-odrriti ekhutshiwe, ayikwazi ukuthengwa kwi-pharmacy ngaphandle koxwebhu olufanelekileyo, kuphela ngokwabo. Imithi "Idrinol" ibhekisela ngqo kwizixhobo ezinjalo zonyango. Yintoni na? Ngokomyalelo oqhotyoshelweyo, eli chiza kufuneka lisetyenziswe kwezi zilandelayo:

• Njengengxenye yonyango olubanzi lweengxaki zokusasazeka kwe-cerebral disorders (ukungakwazi ukuphazamiseka kwesifo se-cerebrascular and stroke ischemic);
• Ngokunciphisa amandla okusebenza, kunye nokugqithisa ngokomzimba (kuquka abo bachaphazelekayo kwimidlalo);
• Kwiinkqubo eziyinkimbinkimbi zeHD (i-myocardial infarction kunye ne-angina pectoris), kunye ne-cardiomyopathy ye-dyshormonal ne-cardiac failure chronic;
• Ukuze unyango lwe-hemophthalmia kunye nokubola kwegazi kwi-retina yamehlo emvelaphi eyahlukeneyo, i-thrombosis ye-vein ye-retina, kunye namasebe awo, ukuvela kwe-retinopathy yemvelaphi eyahlukeneyo (i-hypertensive okanye isifo sikashukela);
• Ukunyangwa kwe-withdrawal syndrome, eyenzeka ekudakwa kotywala okungapheliyo (kunye nonyango oluthile).

Ukungqinelana

Ngaphantsi kweemeko ezingasetyenziselwa unyango "Idrinol"? Iingcali zithi le nkunkuma ayilunyanzelwanga kwizigulane ezine-hypersensitivity kwizinto ezisebenzayo zonyango, ngokunyuka kwengcinezelo engenakunyango (kunye neengxaki ezixhamlekileyo kunye neengxaki eziphumayo), kwaye nangeminyaka eyi-18 (ekubeni ukhuseleko kunye nokusebenza kwezidakamizwa azisungulwa ).

Kufuneka kwakhona kuqatshelwe ukuba izigulane ezinokukhubazeka kunye nomsebenzi we-hepatic kufuneka zisebenzise imithi enombuzo ngokuqapha okukhulu.

Isisombululo seziyobisi kunye neendlela zokulawula kwayo

Ndingayisebenzisa nini i-Idrinol, ixabiso eliboniswe ngezantsi? Ngenxa yesiphumo esinokuthabatha sonyango siyacetyiswa ukungena ekuseni.

Njengengxenye yonyango oluyinkimbinkimbi yemithi ye-cardiovascular pathologies imiselwe nge-0.5-1 g (oko kukuthi, 5-10 ml yesisombululo) okanye i-parabulbarno kwi-100 mg / ml. Le milingo ingasetyenziselwa ngokukhawuleza okanye idibene ezimbini.

Inkqubo yokonyango nale nkunkuma ingama-10-14 iintsuku. Iikhosi eziphindaphindiweyo zichazwe kuphela ngugqirha (ngokuqhelekileyo amaxesha amathathu ngonyaka).

Xa ukusasazwa kwengqondo kungasebenzi (kwisigaba esichukumisayo), isilwanyana senziwa ngeparabulbarno kwi-100 mg / ml okanye nge-intravenously kwi-500 mg (okt 5ml yesisombululo). Izigulane zenziwa emva kwentsuku ezili-10.

Ngendlela yokunciphisa ukusebenza, kunye nokugqithisa ngokomzimba, isilwanyana senziwa nge-intravenously kwi-500 mg (okt, 5 ml yesisombululo) okanye i-parabulbarno kwi-100 mg / ml kanye ngosuku. Inkqubo yeyeza unyango lweeveki ezimbini.

Ngokwe-withdrawal syndrome, ebonakalisa utywala obungapheliyo, isicatshulwa sichazwe nge-500 mg (ie 5 ml yesisombululo) okanye i-parabulbarno kwi-100 mg / ml kabini ngosuku. Ubungakanani bonyango lunemihla eyi-10-14.

Kwi-ophthalmopathology, isilwanyana sisetyenziswe nge-parabulbarno ngama-50 mg okanye nge-intravenously kwi-0.5 ml iintsuku ezili-10, kubandakanywa neyonyango.

Imiphumo emibi

Isigulane siphathwa njani nge-Idrinol? Ama-injection ayifuni ukuba enze iziphumo ezimbi. Nangona kunjalo, kwiimeko ezinqabileyo, ezinye izigulane zisakhalaza ngokudakalisa intlalo. Impendulo eqhelekileyo yile:

• Inkqubo yesisindo (ephakathi): i- psychomotor agitation.
• Iinqwelo kunye nentliziyo: yehla okanye, ngokukodwa, ukwanda kwengcinezelo yegazi, i-tachycardia.
• Iphepha lokugaya: izifo ezibangelwa yi-dyspeptic.
• Ubomi: i- rash, i-skin shaking, i-hyperemia yesikhumba, i- angioedema angioedema, i- eosinophilia.
• Abanye: ubuthathaka jikelele.

Amachiza "Idrinol": ezifanayo kunye neendleko

Esi sidakamizwa sinamanani amaninzi. Phakathi kwezona zilandelayo zilandelayo: I-Angiocarcidyl, i-Mildronate, iVazomag, i-Mildroxin, iKardionate, i-Midolat, i-Medatern, i-Melfor kunye ne-Meldonium.

Ingakanani imithi yama-Idrinol? Ixabiso leli chiza aliphezulu kakhulu. Ngokomyinge, kuya kufuneka uhlawule malunga nama-ruble aseRussia ngama-5 ampoules yeyeza.

Uphononongo

Ziziphi iigulane zithetha ngamachiza afana ne-Idrinol? Iingxelo zithi le nkunkuma ifana kakuhle nomsebenzi. Oogqirha bathi: ukuba uyisebenzisayo ngokwemiqondiso, isebenza ngokuphumelelayo neziphazamiso zentsholongwane yengqondo, ischemic disease, kunye ne-abstinence syndrome, eyenzeka ngoxilongo olungapheliyo. Ukongezelela, eli liyeza lithuthukisa amandla okusebenza kwaye luphelisa ukwanda komzimba.

Kufuneka kwakhona kuqatshelwe ukuba ezininzi izigulane zivuyiswa ngexabiso eliphantsi leziyobisi.

Imiqathango, iimeko zokugcina nokushiya

Iidakamizwa zamachiza, eqinisweni, imithi "i-Idrinol" ibhekisele kuyo, ayikwazi ukusetyenziswa ekuviseni komntu. Zifanele zimiselwe kuphela ngugqirha.

Esi sidakamizwa sisohlwini B. Isiza kufuneka sigcinwe kwiqondo lokushisa elingekho ngaphezulu kwama-26 ° C endaweni engenafikeleleki kubantwana. Iyeza akufanele lichithwe. Ubomi bemfuyo yomkhiqizo weyeza unyango iminyaka emithathu.