Drug "allopurinol": reviews oogqirha, izalathisi, imiphumela emibi

Ukuza kuthi ga ngoku, iziyobisi "allopurinol" yi esisiseko (zaseprayimari pathogenetically nisekelwe) ichiza elo isetyenziswa kunyango lwezifo ezifana sifo. Umntu ngamnye phambi kokuba ukuzama into entsha, ezama ukufumana ulwazi kakhulu luncedo ngayo. Ngoko esikunika ukujongana ngokweenkcukacha ngakumbi xa ezifanayo kumele zisebenze "Allopurinol". Izimvo ezigulane kunye oogqirha baya kuqhutywa kwinqaku lethu yaye niya kwazi ukuba uloyike ngexesha uthatha eli chiza.

iimpawu amayeza we ichiza

"Allopurinol" libhekisela kumalungiselelo iqela protivopodagricakih. Eyona nto ephambili esebenzayo - allopurinol kunye metabolite oksipurinola yayo esebenzayo. Ezi ziphumo pharmacodynamic ngenxa ephula kuyondelelaniswe of uric acid kunye nefuthe lophuhliso urostaticheskogo. ekugqibeleni oku kukhokelela ekunciphiseni eyavela, kulandele dutywa urate.

Ngenxa ukunyibilika ezilungileyo "allopurinol" liye bioavailability eliphezulu. Ichiza ako kakuhle ukusuka mithambo ye emathunjini amancinci. Xa isisu ukuya kwegazi angawi. phambi plasma yegazi kuye kwaphawulwa kangangesiqingatha seyure emva nolawulo, kunye xi ubuninzi kwaphawuleka emva kweeyure 1.5. Ngako oko, le ndzo ubuninzi a metabolite of allopurinol - oksipurinola waphawula iiyure ezintathu emva kokuba kulawulo ngomlomo.

Eli chiza obude isiqingatha ubomi kwaye ukusukela ukuba unako cumulation. Izigulane ekuqaleni unyango, kukho xi elingakumbi kweziyobisi nelizinzisa emva kweveki enye ukuya ezimbini unyango. Ngenxa ekupheliseni "Allopurinol" elide (reviews of oogqirha ukuliqinisekisa) akukhuthazwa ukuba zisetyenziswe ngabantu abane kwezintso. Xa izigulane walondoloza sezintso umsebenzi excretory cumulation akukho ulandelwe.

"Allopurinol": zikhombisa ukuba ukusetyenziswa

Uhlaziya amagqirha echaza le ibango kweziyobisi ukuba kakhulu kwaye nokugwetyelwa kwiimeko hyperuricemia (amanqanaba aphezulu uric acid nganye kwiyunithi umthamo wegazi) e:

• gouty arthritis (sifo);
• Izifo urate enzala (nephropathy, urolithiasis);
• izifo oncological igazi;
• mgaqweni iziphene kwinkqubo enzyme.

Kwezinye iimeko, sebenzisa eli ichiza yonyango yabantwana urate nephropathy, owayebonakele kwisiqalo unyango leukemia yezifo iziphene ezinxulumene ukutya kakuhle ka uric acid, secondary hyperuricemia ezahlukeneyo imvelaphi.

Iimpawu beziyobisi

"Allopurinol" iipilisi (reviews yalumkisa ukuthotyelwa ngokungqongqo kunye neengcebiso amayeza) zithathwa emva kwesidlo, ukuba Akunguye nakanye kuthetha akunakwenzeka ukuba ukuhlafuna, kodwa kunokuba neminikelo yazo yonke, basela ubuncinane iglasi yamanzi ashushu.

Abantu abenza lo amayeza, kufuneka usoloko esweni izidlo zabo, yaye kwimeko impazamo ekutyeni mfuneko yokuba amanqaku makalungiswe umthamo wayo; kodwa kuphela phantsi kweliso ingcali khona.

Ithamo eziyimfuneko ukuze aphathe 'allopurinol "ichiza kumiselwa kuxhomekeke kwisiqulatho uric acid umsinga igazi. Ngokuqhelekileyo, oko isusela ukusuka mg 100 ukuya 300 omnye ukulungiselela ixesha "allopurinol" nganye. Izimvo ezigulane kunye amagqirha malunga nale Umthamo HIV, njengoko kuthathwa ichiza kanye kuphela ngemini.

therapy Igawuthi siqale ngokuqeshwa 100 mg beziyobisi kanye ngemini. Kwimeko yokunqongophala ukusebenza kunye namahlwempu yandisa uric acid idosi ebegqwese ukwanda (100 mg qho emva kweeveki ezimbini okanye ezintathu), nto leyo ekhokelela elebhu olusebenzayo kwezonyango phantsi kolawulo yamanqanaba acid uric. Kwiimeko ezinjalo, idosi avareji kunye nedosi yesondlo elandelayo isusela ukusuka 200 ukuya 400 mg, kodwa kwezinye iimeko, ithamo ungaba kuze 800 mg. Kulo mzekelo, yahlulelwe kwii izihlandlo ezininzi ngosuku.

Xa kutyunjwa ichiza ukuba izigulane insufficiency sezintso kufuneka kugxininisa yokususwa creatinine.

Izimo for "Allopurinol" isiqu

Ichiza contraindicated kwizigulane kunye ukusilela kakhulu kwezintso, kwakunye abakhulelweyo kunye phindeke. Kwakhona akucetyiswa ukuba ichiza kwizigulana yokuba uxabane okanye hypersensitivity amacandelo omnye okanye ngaphezulu yokulungiselela. Akuvunyelwe ukusebenzisa beziyobisi izigulane kunye namaqondo asemdeni of uric acid plasma igazi, ngenxa ukuncitshiswa yayo kunye nempumelelo kunokufikelelwa ngokulungisa yokudla.

"Allopurinol": ziziphumo ebezingalindelekanga

Izimvo lezigulane wasebenzisa iziyobisi okokuqala, zibonisa ukuba kudla exacerbation kakhulu kunokwenzeka nokwanda iimpawu sifo kunye ukuvela ekuthiwa-uhlaselo. Kodwa lo mba elifutshane, yaye akukho mfuneko ukuba woyike ngokwaneleyo ukuze ayeke unyango. Kodwa kwimeko naziphi irhashalala, ubuhlungu okanye ayikho imiqondiso yokuqala kufuneka kwangoko wazise ugqirha wakho. Kule ndlela 'Allopurinol "kufuneka wayeka ngoko nangoko, kwaye njengoko yokuduka iimpawu Technician ungaphinda-ukwabela ichiza, kodwa idosi ongaphantsi (ukusuka 50 mg). Ukwamkelwa kufuneka luqhutywe phantsi kweliso n'wina igqirha ukuya kwaye gumbi.

Phakathi abasabela ezibi e-nervous system kunye nemisebenzi eziphezulu yengqondo kunokubangela uxinezeleko. Ngomhla yinxalenye yophuhliso ngokuxina kwenkqubo umongo hematopoietic ithambo lunqabe yabonakala lubandakanywe nezenzo thrombocytopenia, igazi aplastic.

Xa efumene ichiza lisenokuba neengxaki pathways neswekile, amanqanaba aphezulu fatty kwi plasma yegazi.

Cardio nemithambo inkqubo inokuphuhlisa lwegazi, bradycardia.

Nezihlandlo reactions ezichaseneyo ichiza yaligqiba kukho ukusilela kwezintso kwi umguli.

ifomu Ukukhululwa balawule

"Allopurinol" ezikhoyo azipilisi (30 okanye 50 iiPC. On iphakheji) kwi umthamo 100 okanye 300 mg esisebenza tablet nganye. Inxaxheba kurhwebo lwasemakhaya kukho "Allopurinol Sandoz 300". Izimvo zintle, njengoko ichiza kwi idosi yabelwe kanye kuphela ngosuku, phantse negates ithuba ukuphoswa ukwamkela ichiza.

Ityiwe libanda, iziyobisi

Yityhefu akuvamanga waphawula, kodwa ke kukho iimeko nedosi enye ye-20 iigrem ichiza. Kulo mzekelo, uthi ugagane nezi mpawu zilandelayo: nesiyezi, ukugabha, isicaphucaphu, urhudo. Xa insufficiency sezintso, kunye nolawulo oluqhubekayo amathamo eziphakamileyo iziyobisi waphawula iimpawu kakhulu kunxilwe ngohlobo ifiva, hepatitis, ukusilela oyingozi kwezintso.

Unyango lwetyhefu acute kunye libanda, lingaze, ezijolise nokukhawulezisa nokuphelisa beziyobisi emzimbeni. Akukho ikhubalo ethile. Kuba kukhuthaza ngokukhawuleza beziyobisi emzimbeni iindlela dialysis ezi ubuthi olusebenzayo.

reviews

Ngenxa yokuba ixesha ukuqokelelana kweziyobisi egazini (at a xi ezaneleyo ukunika inyathelo therapeutic) ngumlinganiselo iveki enye, izigulane abaphethwe sifo, kufuneka isetyenziswe phantse ubomi "allopurinol". Izimvo kumagqirha ezi ucacile: ichiza lubonise kakuhle. Kodwa ayikho i "ummangaliso ipilisi 'enokuba basele bakulibale malunga nokugula. Igawuthi - oko kunokuba yindlela yobomi kunokuba sisifo esingapheliyo. Kodwa ke i "Allopurinol" kunceda ukuba ubenemboniselo yangaphezulu lactic acid kunye nokuthintela ukuqhubela phambili kwesifo kwaye yayo engaphezulu inkqubela.

Ngokwemiqathango lula, i indawo "Allopurinol" impendulo kweziyobisi kumagqirha Yinkqubo eneziphumo ezihle, ngenxa yokuba kwiimeko ezininzi isigulane kufuneka athathwe amayeza kanye yonke imihla. Oku kunciphisa amathuba okuba olungekho nangokwamkela medicament kwaye, ngenxa yoko, kwandisa ukusebenza kakuhle unyango.

isiphelo

Ngenxa yoko, iyeza esingundoqo sifo - "Allopurinol". iingcali Izimvo kunye nezigulane, oku kuthetha ukungenisa, eyakhayo, yaye oku kungqina ukusebenza kwalo medicament kunye nonyango lwe Igawuthi nezidubedube acid ukutya uric. Ngenxa ukusetyenziswa kweziyobisi, kukho inani elikhulu lezigulane bafumane ithemba ukunciphisa iingxaki seswekile.