"Coronal": ezibonisa ukusetyenziswa, ncomo. analogue iziyobisi

Development kwezifo sentliziyo iyacotha kwaye wenzeka xa usaqala. Malunga iingxaki ngentliziyo umntu kwiimeko ezininzi wazi xa ngezifo eye yayiqhubeka, kangangokuba kwakufuneka esibhedlele ngokungxamisekileyo. izifo Heart kuyingozi kuba kwenzeka phantse ngaphandle iimpawu. Bona omnye wemiba ephambili yokufa emhlabeni. Nokuba isigulane asinde ukuhlaselwa sisifo sentliziyo, ukuba sibuyele kwindlela eqhelekileyo yobomi oko akunakwenzeka, kwaye ke ngoko kufuneka baziqhelanise isimbo esitsha, kunomda nangakumbi. Iyaluthintela uphuhliso yeengxaki ezinkulu nesifo sentliziyo unako, ngexesha ukuba unesifo. Ngoko ke, kufuneka baye bahlolwe azizithintelo ukugcina impilo kwentliziyo yakho.

isifo sentliziyo

Kukho imiqondiso emininzi asenokubonisa ukuba uphuhliso iingxaki zentliziyo. Ukubona kwezi mpawu kufuneka ngoko nangoko uye eklinikhi, apho ukuhlolwa ngokucokisekileyo kuya kunceda ukufumanisa isifo kunye nokuthintela iingxaki kunokwenzeka.

Ezi mpawu zixhaphakileyo manqanaba okuqala nesifo sentliziyo zibandakanya ukudinwa, yaye ubuthathaka jikelele. Basenokuba ezinxulumene ntshikilelo okanye ntshikilelo phezulu, kodwa kwakhona kube ngumqondiso ukusilela kwentliziyo. Njengomgaqo, ukudinwa akayi kumka nasemva kokuba abanye, kwaye wongeza omnye kunye ingqiqo ka ntshikilelo, ukungabi namdla, impilo enkenenkene ngokubanzi. Olunye uphawu ukuba akwazi ukubonakalisa uphuhliso lwemiphunga okanye intliziyo ukuhluleka ukuphelelwa umoya, yaye oko kunokuthi kwenzeke naxa umntu sikwimo yoxolo epheleleyo.

uloyiko obukhulu, uxinezeleko okanye umsebenzi elide emzimbeni wonke umntu esempilweni kunokubangela iyangongoza intliziyo, yaye oku njengento eqhelekileyo. Ukuba tachycardia sivame ukhathazekile yaye ngaphandle nasiphi na isizathu, sonke sithethe phambi yokuphazamiseka karhulumente kwenkqubo sentliziyo. Ezinye iimpawu zesifo sentliziyo zibandakanya ilahleko yemali eseleyo okanye isiyezi ngesiquphe, niphele, ubuhlungu kunye neentlungu esifubeni. Ezi mpawu yoko umntu ukutyelela ugqirha. Ize iwise uviwo yenkqubo sentliziyo.

Drug "Coronal"

Ukuba isigulane kuye kwafunyaniswa kwinqanaba yesifo sentliziyo, engaquki kufuna utyando, yena emiselweyo amayeza. Iziyobisi nxamnye nesifo sentliziyo inceda izigulane ukumelana iimpawu zesifo kwaye ukuqhubekela phambili kwayo. Umntu kufuneka ilungiswe indlela yokuba ukuba ufuna ukwenza ubomi bakhe, kwakufuneka ukutshintsha umfanekiso walo, ingakumbi, ukunika imikhuba emibi, ukuba badle, ukudibanisa umthwalo oluphakathi kunye nabanye.

Namhlanje ezishelfini abantu ezikhemisti eninzi ngemithamo ezijoliswe ekulweni neengxaki zentliziyo. Enye amachiza ezininzi eziqhelekileyo ezo amiselweyo "Coronal" tablet. Iimpawu zibonisa ukuba ukusetyenziswa kweziyobisi isenokuba kulandelayo: kobuchopho isifo sentliziyo, arrhythmia, lwegazi, ventricular okanye supraventricular arrhythmias kunye nabanye. Phambi kokuba uqale ikhondo unyango, kufuneka udibane nogqirha wakho. Medicine "Coronal" lineziphumo ngokwaneleyo kakhulu emzimbeni kuqala, kukho uluhlu Izimo kunye kunokubangela iziphumo ebezingalindelekanga. Iyafumaneka emacwecweni bhanya-camera. Ugqirha unakho ukumisela ichiza "Coronal" kunye analogue yayo.

Pharmacology

Le medicament "Coronal" liye antianginal, umfutho kunye nesenzo antiarrhythmic. Le ikhetha beta-blocker kunciphisa ukuyilwa elibujikele AMP ukusuka ATP kwaye iyakwazi kuthintele beta-adrenergic receptors zentliziyo. Kwakhona, ichiza "Coronal" kunciphisa contractility engabalulekanga kunye nezinga intliziyo, conductivity yayo excitability.

Isiphumo iqinile beziyobisi kubonakala kwinto yokuba inegalelo yokuncipha kwenani kwimveliso intliziyo. "Coronal" - iipilisi ukubuyisela uvakalelo okuqhelekileyo baroreceptors, zinqanda umsebenzi kwinkqubo reninangiotenzivnoy, kuchaphazela inkqubo luvo. Xa izigulane abaphethwe lwegazi, umfutho yabonwa emva kweentsuku 2-5 emva kokuqalisa isicelo. Emva kweenyanga 1-2 iphawulwe ukusebenza iqinile izinzile nezinyangayo.

Ukulungiselela "Coronal", ezibonisa apho abe imisebenzi ebanzi ngokwaneleyo ngandlela antianginal. Iipilisi ukukhuthaza zobude diastole ukuphucula perfusion kwemisipha intliziyo, ukunciphisa imfuno ioksijini ngokunciphisa izinga intliziyo. Isiphumo antiarrhythmic beziyobisi kukuba layo ukuphelisa izinto arrhythmogenic. Phantsi impembelelo yayo ukucola Uhanjiso atrioventricular sehlise izinga excitation le sinus kunye pacemakers ethunjini.

Ukusebenzisa izixhobo eliphakathi-idosi ichanekile ngaphantsi ngokukhawuleza kwi imithambo peripheral, izihlunu agudileyo bronchi, injeke, izihlunu skeletal, ukutya ekudleni. Ichiza Akukho kulibazisa ion sodium emzimbeni, ukufunxeka wayo umalunga 80-90%.

Ubungqina obubonakalayo buxela

Phambi kokuba uthathe "Coronal", kufuneka udibane nogqirha ngubani na oya kuninika imiyalelo ecacileyo malunga idosi rhoqo kulawulo. Awukwazi ukuqala ezithatha ichiza ngokwabo, kukho umngcipheko nobungozi kwimpilo yabo etyhidiweyo, kunye neziphumo vuhlayiseki.

Xa ichiza ezibonisa "Coronal 'ukuba isetyenziswe ikakhulu enganqamlwanga lwegazi kunye nesifo sentliziyo. Le idosi yemihla ngemihla - 5 mg. Amayeza eziphambili esisebenza "Coronal" - bisoprolol. izinga eliphezulu ngemihla ukuya ku-20 mg, ngoxa izigulana sesibindi kakuhle umsebenzi yesiqhelo - 10 milligrams. Ulapha kuzo zonke iimeko ayilungiswanga ngamnye, kuthathelwa ingqalelo zonyango ukusebenza kunye nentliziyo rate. Ukunciphisa ithamo ichiza "Coronal" kufuneka ngcembe, akunakwenzeka ukuba uyeke ukufumana ke ngequbuliso. Oku kuyinyani ngakumbi kwezigulane sifuba angina (isifo).

Izimo

Kukho uluhlu Kwiimeko apho kubhetele ukuba bashiye ukusetyenziswa kweziyobisi "Coronal". Ubungqina obubonakalayo buxela ukuba Sebenzisa yesifo sentliziyo isenokungabi nto kuphela, ukuze uqale ikhondo unyango. Ugqirha kufuneka ngenyameko ndikunyibilikise sihlolisise sesigulane ukhuseleko yokugqibela.

Ichiza contraindicated kwizigulane kunye ukusilela decompensated ngentliziyo, ukusilela intliziyo etsolo, ukothuka cardiogenic, cardiomegaly, angina Prinzmetal, SSA syndrome, ibloko atrioventricular-II III ngenkulungwane., Kwafa Sinoatrial. Musa ukuthatha njengendlela "Coronal" kwizigulane ekufuneka uvakalelo ngamnye ukuya ichiza. Ayikhuthazwa ukuba amisele ukuba abasetyhini ngexesha zisanyisa, kwakunye idityaniswe nokusetyenziswa Mao inhibitor.

Kwiimeko kakhulu, kodwa lo mzekelo ukulungiselela ngenyameko kakhulu asetyenziswa ekunyangeni izigulane myasthenia gravis, claudication ngakanye, syndrome ka Raynaud, ukusilela hepatic, ukusilela intliziyo esinganyangekiyo, pheochromocytoma, lactic metabolic, isifuba inyumoniya, emphysema, isifo seswekile. Izimo kusetyenziso kunokuba ukudakumba, ukhwekhwe, hyperthyroidism, yobuntwana kunye nokuguga, ukukhulelwa. Kuvunwe indlela iziyobisi "Coronal" (impendulo kumagqirha kule idibane) ngethuba lokukhulelwa kunokuba njalo kuphela xa isibonelelo ukuya umama izihlandlo eziliqela ngaphezu ingozi yokuba umntwana.

libanda

Isigulana kufuneka balandele ngqo neemfuno oyingcali, ngenxa yokuba i libanda kunokubangela iimpawu ezinobungozi. Iimpawu ezongezelelweyo ezixhaphakileyo ukuba zibangelwa yi-libanda, lithetha "Coronal" - bronchospasm, ukusilela intliziyo, hypotension, bradycardia. Ukunxila ibangela ukusebenza cardiodepressivny kakhulu oxhaphakileyo phezu ukuncipha contractility nokuncipha rate intliziyo. Isigulane basenokuba ukuphazamiseka yokuphefumla okubangelwa bronchospasm.

Ukuba isigulana indlela ezingeyondalo iyeza, kufuneka athathe amanyathelo yokungenelela kuzo. Into yokuqala ukuyenza - oko enze lavage esiswini kulandele yolawulo ehnterosorbentov (wamalahle iyasebenza). Kwakhona kusela laxatives (sodium sulfate). Ngaba ukuphelisa iimpawu kunxilwe usebenzisa atropine (0.5 -2.0 mg) yegazi. Kwakhona kwezi meko ukusebenzisa glucagon 1-5 mg. Xa ivela bronchospasm kufuneka usebenzise bronchodilator iziyobisi (zetoti "salbutamol" okanye "Fenoterol").

imiphumela emibi

Ukulungiselela "Coronal" kunokubangela iziphumo ezingalindelekanga, owenza yonke eziphilayo. Engozini:

• nemithambo yegazi;
• luvo;
• isixokelelwano sokuphefumla;
• iphecana zesisu;
• inkqubo enzala;
• izixhobo ezibonwayo;
• eluswini, izihlunu, amalungu.

Ngomhla inxalenye yegazi iingxaki ezinjalo kungenziwa wambi, njengoko paresthesia, ukuphazamiseka Uhanjiso, bradycardia, hypertension intolerance, lisibekele uxinzelelo lwegazi. Kwizigulane kunye nesenzeko Raynaud okanye claudication uveza mandundu iimpawu.

Ichiza ziziphumo ebezingalindelekanga "Coronal" kwaye kungabangela luvo, oko kukuthi, utshintsho engqondweni, amaphupha acacileyo, yokulala, isiyezi, intloko ebuhlungu, ukudinwa. kunqabile kakhulu, kodwa kwi izixhobo ezibonakalayo nefuthe lithetha "Coronal". Izimvo ezi meko, i-ethe, kodwa ngenxa yokuba sesichengeni ichiza ukuze sibe sibi umbono, kunciphise ukukrazula, kude kuphuhliso conjunctivitis.

Iimpawu ezifana bronchospasm, dyspnea, nokuthimliswa, kunye ngeempumlo ingxinano ungase uphazamise abo nezigulane ezehlelwa asthma inyumoniya. Kwiimeko ezinqabe kakhulu ngayo kwenzeka iziphumo hepatotoxic of bisoprolol, nto leyo kumiselwa isicaphucaphu, urhudo, ukuqhina kunye neentlungu esiswini.

Phakathi kwezinye imiphumela emibi ebangelwe sisenzo ichiza "Coronal" uhlolo isigulane uqaphele oku kulandelayo: ukwanda ukubila, ukurhawuzelela kunye anozizi eluswini, arthropathy, amahlaba kunye izihlunu iintlungu. Ayifane khathaza dysuria kunye erectile nokuphazamiseka ebangelwe sisenzo iziyobisi "Coronal". Analogs kwakhona iziyobisi kunokubangela iziphumo ebezingalindelekanga kwi emzimbeni. Ngoko ke, kwimeko nganye, qiniseka ukuba udibane nogqirha wakho uze ulandele imiyalelo yakhe.

oyi

Ukongeza Izimo kunye neziphumo ebezingalindelekanga, kukho inani leemeko apho ukusetyenziswa kweziyobisi ukuba alumke kakhulu kwaye uhlala phantsi kweliso gqirha. Oku wayeyixhalabele kunye neemeko ezifana ukusilela congestive sentliziyo, isifo seswekile, ukudakumba, myasthenia gravis, ukhwekhwe, hyperthyroidism, ukuphazamiseka eqhelekileyo yokusebenza esibindini okanye intso, lactic metabolic, nendlala, Prinzmetal angina.

singathathwa nezifo ezinganyangekiyo zemiphunga obstructive lithetha "Coronal" analogue kunye nezinye beta-blocker, kodwa kuphela xa zidityaniswe kunye bronchodilators kwaye ngokwemithamo ezincinci. iindlela Feohromotsitome kufuneka zithathwe ngaxeshanye kuvalwe iindlela ii-alpha-adrenergic. Idosi kufuneka ilawulwe emva kokuba iimviwo kwesibindi kunye nezintso.

Lwegazi kweziyobisi kunokunyangwa kuphela phantsi kweliso unyango rhoqo. Ukwehla ukusabela adrenergic kontrregulyatsii kwaye anaphylactic mandundu ikhondo ukusabela izigulane zithathe beta-blocker. izigulane asebekhulile nabo kuthi uvakalelo oluphezulu naxa usebenzisa amathamo eqhelekileyo ichiza, ngokunjalo kufuneka esweni rhoqo.

Ukuba ufuna utyando imbalo, ukusetyenziswa kweziyobisi rhoxisa iiyure 48 phambi kotyando, kwangaxeshanye musa zenjenjalo ngokukhawuleza, kodwa ngokuthe ngcembe. Ukuba isigulana na ichiza ezibonisa "Coronal" ukusetyenziswa, kufuneka ukuba silumke kakhulu kwimisebenzi efuna izinga eliphezulu reactions ngokwasemzimbeni nangokwasengqondweni (esebenza ubude, basebenza ngoomatshini, umsebenzi kunye ngoomatshini esiyingozi, beqhuba, njalo njalo).

imithi

Ukuthatha "Coronal" (tablets) ngaxeshanye kunye namanye amachiza kufuneka ithobele ukhuseleko. Ingakumbi kumayelana indibanisela nge Mao inhibitors ziye zaphawulwa emva kokupheliswa uxinzelelo lwegazi. Ukudibanisa blocker beta enezicatshulwa allergen zeemvavanyo imvaba zamavumba esetyenziselwa immunotherapy, kukho ingozi yokuba ingqondo reactions namachiza okanye nezidlo.

Ekusetyenzisweni antiarrhythmics kweeklasi I III ( "Dizopiramid", "Sotalol", "Quinidine" "Amiodarone", "Lidocaine") Kwakhona kufuneka silumke. Xa ulawulo ngaxeshanye iziyobisi umfutho kunye tablets "Coronal" akwazi potentiate imiphumo lokuqala. Ukuba ukusetyenziswa kweli chiza nodibaniso 'Guafatsinom "," Digitalis "," Clonidine "," reserpine ", oko kungacothisa ngokubamba inkqubo conductive intliziyo pulses zombane.

ukulungiselela therapeutic ukusebenza "Coronal" kunokulungiswa kukungakhuseleki arhente sympathomimetic (iziyobisi antitussive, ukuthetha kwam ngeempumlo okanye wamehlo). Activators enqanda hepatic bawaphikise ukuncitshiswa eziphilayo isiqingatha-ubomi beta-adrenoceptor agonist. Ulawulo ngaxeshanye iziyobisi antiarrhythmic, kunye calcium channel blocker amaqela "Nifedipine" yaye "Verapamil" kunokubangela bradycardia, ukusilela intliziyo okanye nokuphazamiseka Uhanjiso.

unyango ngaxeshanye iziyobisi "Coronal" yaye "Clonidine" kunokubangela uphuhliso lobunzima unesifo. Ukuba yokwamkela yokufundwa iziyobisi 'Coronal' abe kwizigulane kunye seswekile, kucetyiswa ngamandla ukuba esweni rhoqo amanqanaba iswekile yegazi. Oku kungenxa yokuba blocker beta nga potentiate ifuthe amachiza alwa isifo seswekile kunye insulin, iteyiphu yephepha iimpawu hypoglycemia.

Izimvo emithi

"Coronal" oogqirha Drug ukumisela kwizigulane kunye nesifo sentliziyo. Kodwa ukuba kunjalo lonke eli yeza ukusebenza? Ukuhlalutya nokubuyekezwa ngayo, ungenza kwisigqibo jikelele ukuba ifuthe ichiza emzimbeni yomguli kuxhomekeke kwimeko nganye ngamnye. Abo nethamsanqa ngokwaneleyo ukuba nazo iziphumo ebezingalindelekanga ezihle kakhulu malunga ukulungiselelwa "Coronal". Izimvo ezigulane abaye bavakalelwa iimpembelelo ichiza, ayikho kamnandi kangaka. Noko ke, iingxaki uya kuziphepha. Phambi kokuba uthathe "Coronal" (amacwecwe), umyalelo kufuneka ngenyameko ngokutsha funda-izihlandlo eziliqela, kuba ukungakhathali kwakhona kwenzakalisa impilo yakho.

Into yokuqala ukuba izigulane zithi ukunciphisa izinga lentliziyo, nokwehla kancinane uxinzelelo lwegazi, ukuphucula imeko jikelele yesigulana. Emva kweenyanga eziliqela isicelo, oogqirha Siyaleza ukunciphisa umthamo, kuba ukubetha kwentliziyo kunye negazi xi lifikelele nanjengokwesimo kwaye akukho mfuneko ukuthoba ezingakumbi. Izigulane kwakhona uqaphele ukuba xa ulandela yonke imiyalelo logqirha, imiphumo ebuhlungu kufuneka ukuboyika ichiza. Kodwa abo ngokuzimeleyo isigqibo ukutshintsha idosi yemihla ngemihla okanye wasilela ukulumkisa oogqirha malunga ukusetyenziswa nezinye iziyobisi, kufuneka iingxaki, nto leyo kwezinye iimeko esibhedlela. Yiloo nto ke kufuneka ungalibali ukuba kukho na pack ngamnye iipilisi "Coronal" umyalelo manual.

analogs

Drug "Coronal" enoluhlu olubanzi analogue - amayeza, aba bakhoyo apha kweziyobisi enye esebenzayo. Ahluke intengo, ilizwe wokwenziwa, indlela yokusebenza, Izimo, ubukho okanye ukungabikho yeziphumo ebezingalindelekanga.

Njengayo nayiphi na amayeza, ububanzi bayo kwaye lithetha "Coronal". analogue zayo ezifanayo ukuba into esebenzayo kuzo - bisoprolol. Avamise kakhulu iziyobisi eziveliswa ekhaya. inzuzo yazo ithathwa ngexabiso eliphantsi (xa kuthelekiswa amazwe) kunye ukusebenza eliphezulu. Ingakumbi, loo iziyobisi ukuze kuchazwe: "Aritel", "Aritel Kor", "Biprol" "Bisoprolol" "Bisoprolol-Praana", "Niperten". Ukuba ziyafumaneka kuzo zonke ekhemesti, kwaye ixabiso yabo isusela ukusuka 30 ukuya engange ezilikhulu pack nganye.

analogue Ithunyelwe "Coronal" ichiza kwakhona kwenziwa asolwa enkulu "Bidop" (saseHungary), "Biola" (Slovenia) "Bisogamma" (Germany), "Bisokard" (sasePoland), "Bisomor" (India), "Bisoprolol- Lugano "(Ukraine)," bisoprolol-Teva "(uSirayeli) kunye nabanye. Ezithandwa kakhulu phakathi amachiza ngaphandle bekhetha amayeza isiJamani "Concor". ixabiso layo ngu-4 phinda iindleko ichiza "Coronal" kwaye imalunga 180 engange. Ngokubanzi, iziyobisi ukungeniswa ekhemesti ezinikezelwa ngamaxabiso esukela engange 300 ukuya 600 pack nganye.