Yintoni 5-alpha reductase? Imixube - Enzyme inhibitor

Zonke iinkqubo emzimbeni kwenzeka kunye nxaxheba kwezinto bioactive, ingakumbi enzymes. Libhekisela kwiqela iziyobisi proteinaceous 5-alpha reductase. Ngelishwa, kwezinye iimeko, ukungasebenzi kwenzeka kwinkqubo Yindibanisela izinto esebenzayo leyo ekhokelela ukungasebenzi yonke eziphilayo. Ngoko imele i-enzayim ye esebenzayo kwaye apho iimeko, oogqirha basebenzisa inhibitors we-5-Alpha-reductase? Zintoni iziphumo unyango kunokwenzeka? Ingaba kukho naziphi na Izimo? Iimpendulo zale mibuzo umdla kubafundi abaninzi.

5-alpha reductase: ntoni na?

Okokuqala, makhe Masiqonde imisebenzi esisiseko ye kweziyobisi. 5-alpha reductase - compound proteinaceous, i-enzayimi leyo inxaxheba kule nkqubo steroidogenesis. Le into eshukumisa ukuguqulwa testosterone (oyindoda hormone sex) zibe dihydrotestosterone, nto leyo lubonakala ngokuba nefuthe kakhulu. Ngaphaya koko, i-enzayim ikhuthaza ukuyilwa allopregnanolone kunye nezinye neurosteroids.

5-alpha reductase iveliswa ubukhulu becala amalungu uhlelo zokuzala, ezintweni ezithile prostatic kunye vesicles ZakwaLizwi Zehlabathi. A imali encinane enzyme nalo ekuveliseni iiseli eluswini, zoboya, kunye namalungu e-nervous system.

Kutheni inhibitor?

Inhibitor we-5-alpha-reductase - iziyobisi ukuvimba ukuveliswa enzyme kunye echaphazela isixa zamadlala obudoda emzimbeni. Namhlanje, loo machiza asetyenziswa ngokubanzi. Umzekelo, badla ezimiselwe ukufundwa izigulana induna. Iziyobisi kweli qela uncedo ukuthintela alopecia (nenkqayi).

Kukho iindawo ezininzi yokusebenzisa iziyobisi ukuba zinqanda imveliso enzyme ezifana-5-alpha reductase. Blocker of DHT (dihydrotestosterone) zisetyenziselwa ukunyanga hypertrophy prostatic. imithi efanele inceda ukwehlisa umthamo prostate in ukudumba.

Ukusebenza unyango iye yaqinisekiswa izifundo esayensi kwenziwa elebhu kunye negama ehlabathini lonke.

Inhibitor 5 Alpha redukazy: amachiza zokwenziwa

Ukuza kuthi ga ngoku, ekwenziweni iziyobisi kweli qela kukho izinto ezimbini eziphambili ezisebenzayo:

1. Dutasteride i inhibitor uyakhetha kwaye ihlala ingumdlali isetyenziselwa ukunyanga hyperplasia nabungozi ye endlaleni. Ichiza kakhulu zabantu kubizwa ngokuba "Avodart".

2. Finasteride - into eyenziweyo ebangela ukwehla kwinqanaba enqanda igazi nje kuphela, kodwa kwakhona ngqo kwi ijwabu wendlala. Le nguqu ithatha malunga nama-24 iiyure. Maxa wambi asetyenziselwa kwi ekunyangeni umhlaza yesinye, nangona i-100% ngempumelelo yayo ayenziwanga eqinisekisiwe. Ukukhethwa iziyobisi, njengenxalenye apho kukho finasteride, ngakumbi: "Alfinal", "Urofin", "Finasta" "Proscar", "Zerlon", "Penester" kunye nabanye.

amayeza esintu

iziyobisi Synthetic, Kakade ke, uyakwazi ukunika nemiphumo ucaca ngakumbi. Kodwa iziyobisi kaninzi ezisetyenziswayo isityalo-based - bachaphazela umzimba lithambile yaye phantse engeyongozi. ngeendlela ezinjalo, ngokuzenzekelayo, alisetyenziswa kuphela izifo endlaleni. Zinceda ekulweni ilahleko iinwele (alopecia kuquka abafazi) kunye induna.

Kuba unyango kweenkqubo hyperplastic prostate palmetto iziqhamo zisetyenziswa kakhulu ukuba zizityebi okunamafutha acid kunye phytosterols. Isoflavones - Elinye iqela iikhompawundi leyo ilifa iipropati antiandrogenic. Phela, liye iimpawu ezifanayo kunye umba. izityalo Ingca ezisetyenziswa ukomeleza iinwele.

Ingaba kukho naziphi na iziphumo ebezingalindelekanga zinokwenzeka?

Kufuneka kuthathwe ngononophelo blocker Amachiza we-5-Alpha-reductase, ingakumbi xa kuziwa kwiindlela zokwenziwa. Isibakala sokuba la machiza senze ngqo kwi balance hormone yesigulana.

ulawulo Chronic, izigulane ezininzi uqaphele utshintsho ebomini ngokwesondo. Ngokukodwa, kubekho kophulwa umthetho amandla nokwehla drive ngesondo. umfowunelwa ngokwesini badla kukhatshwe iingxaki: ulwakhiwo nesktoykoy, iintlobano zesini emfutshane, njalo njalo iziphumo ezingalindelekanga kufuneka ibandakanye ukuncipha nomthamo ejaculate ... Ngenxa ekuhleni kwenani neurosteroids kwizigulane asakhasayo ukudakumba, nangona oku side kunqabile kakhulu.

Therapy ngokuyimfuneko kwenziwe phantsi kweliso gqirha. Xa kuziwa amalungiselelo esintu, umzimba ngokukhawuleza luye kusetyenziswa kuyo, ngoko ke isiphumo iyeza kancane kancane kuze ubuncinane. Kwelinye icala, amayeza eengcambu zikhuselekile noko impilo.

Izimo ukusetyenziswa inhibitor

Akukho kuzo zonke iimeko, ungenza uthathe amayeza gqiba umsebenzi enzyme ebizwa "5-Alpha reductase." La machiza Akukho eboniswe izigulane phambi ukuphazamiseka zosulele ukudumba kuquka prostatitis.

Phambi ekwenzeni ukuba inkqubo yonyango kuyimfuneko ukuba baphumelele isifo ngokupheleleyo eziphilayo. Ukusola Oncology waqhuba i biopsy lwe endlaleni. Ubukho yobubi na contraindication ukuba ukusetyenziswa kweziyobisi gwenxa. Kwakhona iyeza le nto yenziwa izigulane kwixesha postoperative kwaye kukho ukusilela kwezintso.