'Sulfasalazine' lithetha. Imiyalelo yokusebenzisa

Ichiza "sulfasalazine EH" ikuba- ukudumba, anti-samathambo, immunosuppressive, arhente emathunjini bacteriostatic. Indlela yokusebenza isekelwe phezu kwiipropati zecandelo iziyobisi esebenzayo.

salazosulfapyridine into esebenzayo i zintsholongwane evela kwiqela sulphonamides. Eli candelo abe umsebenzi bacteriostatic nxamnye gonococcus, streptococci, diplococci, E. coli.

Active nto-5-aminosalitsillovaya acid uye iipropati anti-ukudumba, oko kusenza kwezithandani of prostaglandin amagama kunye inhibition of cyclooxygenase.

Lithetha "Sulfasalazine" (umyalelo zokusetyenziswa iqulethe iinkcukacha) iibhloko inguqu lymphocyte kunye abangaphangeliyo monocytes. Ichiza ichaphazela eselula, kunye nezifo humoral.

Le medicament ayiqondakali etsalwe iphecana zesisu.

Ichiza "Sulfasalazine" umyalelo manual ikhuthaza ukuba proctitis sisilonda, okwenziwa sisilonda nonspecific (sikabhobhosi). Kwezi ezimbi, lo medicament esetyenziswa ukunyanga exacerbations kwaye nonyango yolondolozo kuxolelwe.

Lithetha "Sulfasalazine" yemiyalezo makwenziwe sisifo Crohn kaThixo (kwi eliphakathi kunye nowobulali iintlobo exacerbation).

Ichiza kwakhona ezimiselweyo isifo samathambo (zolutsha ngokunjalo).

Medicament "Sulfasalazine" umyalelo manual icebise ukuba emva kokutya. Idosi kufuneka kusekwa ngamnye ngokuhambelana yengxinano iimpawu kunye neziphumo ebezingalindelekanga kunokwenzeka.

Ngokuqhelekileyo, umntu omdala yabela milligrams 500 ukuya 2000 kane ngemini ukuphungula impawo sifo. Kamva, isigulane idluliselwa kunyango yesondlo. Esithathwa kulo mzekelo - 500 milligrams kathathu, kane ngemini. Ubude unyango - kwiinyanga ezimbalwa.

Esithathwa abantwana: emihlanu ukuya kwiminyaka esixhenxe - amaxesha 250-500 milligrams ezintathu ukuya kwezintandathu ngosuku, iminyaka esixhenxe - to amaxesha 0.5 grams ezintathu ukuya kwezintandathu ngosuku.

ithamo Adult therapeutic - 1.5-3 grams. Njengoko yokwenza ubonisa, isiphumo kwenzeka emva kweeveki ezintandathu ukuya ezilishumi. Qhubeka therapy ubuncinane kangangeenyanga ezintandathu.

Ichiza contraindicated kwiimeko kwegazi, porphyria, ochazwa ukuphazamiseka kwesibindi okanye nezintso, hypersensitivity (kuquka salicylates, sulfonamides). Musa ukumisela ichiza "Sulfasalazine" abantwana ukuya kwiminyaka emihlanu. Ngaba contraindicated ngexesha zisanyisa. Ukuba kuyimfuneko, sebenzisa imithi ngexesha lokuncancisa, ekufuneka senze isigqibo malunga lokuyeka zisanyisa.

Ngexa lokukhulelwa, ichiza nga lenziwe ngokwale ngokungqongqo kwakuthethwa idosi ubuncinane kwezonyango phantsi kweliso zonyango. Asazi singacebisi ezithatha ichiza "Sulfasalazine" kwi senyanga yesithathu yokukhulelwa.

Uninzi iziganeko ezibi idosi medicament ixhomekeke kwamkelwa yaye ngenxa yomsebenzi salazosulfapiridina (esisebenza).

Iyeza kungabangela nephropathy peripheral, isiyezi, nephritis Embi, ubuthongo, ukuduma. Ngexesha unyango ukuphazamiseka kungenzeka kwizintso, urhudo, umlambo, ukwenzakala esiqwini lung, leukopenia, ubudlolo kwakunye oligospermia (idlule). reactions Ezingalunganga nazo ziquka ukugabha, pancreatitis, agranulocytosis, Njengokungeniswa anaphylactic, igazi, urticaria. Kwiimeko ezinqabe kakhulu, sigulo ibonakala umsebenzi luvo peripheral, ngayo ulusu.

Phezu ukusetyenziswa kweziyobisi Kucetyiswa ukuba usele iziselo.

Akukho bungqina ingaba ichiza "Sulfasalazine" analogs ukwimo esebenzayo.

Ngaphambi ngokusebenzisa ichiza, iingcali bacebisa ukuba uqhelane kunye nesishwankathelo.