"Spironolactone": analogue, uqeqesho, ukusetyenziswa, inkcazo kweziyobisi

"Spironolactone" - na potassium kunye magniysberegayuschy umchamo. Ichiza yindlela enamandla umchamo, nto leyo ethintela iziniki-omzimba neetyuwa ebalulekileyo. Kwakhona lihlisa asidi ngumchamo. Kuyimfuneko ukunikela ingqalelo, uzama ukubuyisela unyango of "spironolactone". Analogs beziyobisi azisoloko ilifa propati.

Isakhiwo kunye Nokuhlanganiselwa

Eli chiza ifumaneka azipilisi. Icandelo esebenzayo i spironolactone. Xa ipilisi enye iqulethe 25 okanye 100 mg ukwimo. Kwakhona, le nto ndiyibhalayo amacandelo abancedisayo: neetapile starch, monohydrate, lactose, povidone, calcium stearate. Macwecwe ajikelezayo zibekelelwe ibhokisi yekhadibhodi lamaqhosha-20.

imiphumela kwemithi

Drug "spironolactone" yinto yokuqala aldosterone. Lo hormone adrenocortical. Aldosterone yokudibanisa ne protein receptors kwiiseli nephron distal kunciphisa kukhuthaza sodium kunye namanzi kwandisa potassium leaching. "Spironolactone" zikhuphisane kwale hormone kunye nezenzo nje eyahlukileyo. Amalungiselelo ikhuthaza kukhuthaza amanzi kesodiyam evela emzimbeni, kugcinwe ion potassium. balance Electrolyte ke bangaphazamiseki.

Okwangoku ngokugqibeleleyo wafunda pharmacodynamics beziyobisi. Phezu ukwamkelwa iphecana zesisu ngayo ako ngokukhawuleza ngokuzibophelela kwi iiproteni plasma. Bioavailability iipilisi nama-99%. Enye wadubula lo Kadir ibalekisa kukufakwa into esebenzayo esebenzayo iziyobisi.

Isiphumo therapeutic, ngokutsho myalelo kwenzeka zingaphelanga iintsuku ezi-5. Kufuna olwenzeka yayo kancinane emzimbeni ukuya yoxinaniso ethile ukuze isebenze ichiza. Kungenjalo, kulo mkhuba yamayeza ibizwa ngokuba nemiphumo lonyuselo. into esebenzayo ungena ngokukhawuleza kwi ubisi lwebele, kwaye zivela emzimbeni kunye endleni kunye nomchamo. Zeziphi izifo oogqirha ukumisela "spironolactone"?

Ubungqina obubonakalayo buxela

Imiyalelo ukuba "spironolactone" ingxelo ukuba ichiza ilungiselelwe ukunyanga izifo kunye ezimbi zilandelayo:

• syndrome Edematous owenzeke imvelaphi ukungaphumeleli kwentliziyo.
• Hyperaldosteronism.
• BP Kubalulekile.
• hyperaldosteronism Secondary okubangelwa kwesibindi.

Ukuze unyango lwe sifo kufuneka kuqale emva kokubonisana nogqirha.

Izimo

Kwezinye iimeko, ayikhuthazwa ezithatha ichiza "spironolactone"? Iimpawu zibonisa ukuba ukusetyenziswa uchazwe apha ngasentla akukho ngunobangela self-unyango. Eli chiza iziphumo ebezingalindelekanga ezininzi kwaye Izimo.

Imiyalelo eya Administration Drug wathi ukusetyenziswa kwayo ngeenjongo zonyango akukhuthazwa kubantu abane Addison bakaThixo izifo, hypercalcemia, isifo seswekile. Ngononophelo kakhulu kufuneka zisetyenziswe ichiza kubafazi kunye yezitenxo sexesheni, ukukhula ibele.

Imiyalelo yokusebenzisa

Le medicament ilungele lolawulo ngomlomo. Iidosi emiselwe igqirha qho ngamnye, ezisekelwe ubukhulu kwephulwa balance yamanzi-electrolyte kunye namanqanaba hormone malunga nesigulane eso.

Xa nokudumba yabangela bangonwabi syndrome, unyango uqalwe nge 100-200 mg beziyobisi ngosuku. Idosi kufuneka yahlulwe amathamo amabini okanye amathathu. Ubude unyango malunga neeveki ezintathu. Kwimeko hyperaldosteronism kunye potassium eliphantsi medicament igazi "spironolactone-Darnitsya" sabelwe mg 300 ngosuku.

Xa a syndrome hydropic, wayanyaniswe nohlobo ezingapheliyo of insufficiency kwentliziyo, unyango na iintsuku ezi-5. Amacwecwe ziqhutywa ngendlela umthamo 100-200 mg. Ukongezelela, izigulane zidla emiselweyo thiazide kunye loop womchamo. Xa Dynamics ezintle idosi ukuchacha ebegqwese kutsho ku-25 mg ngosuku.

imiphumela emibi

Ziziphi na iziphumo ebezingalindelekanga 'spironolactone "? Analogs yale chiza obukhulu amahlwempu. "Spironolactone", ngokuchaseneyo, esibonakala ukufakwa olukhawulezayo kunye nesiphumo esihle nezinyangayo. Ngamanye amaxesha bene ziziphumo ebezingalindelekanga, nto leyo kwifomu eyandisiweyo ichazwe ngezantsi.

1. Nethe: inguqu esiti-base eseleyo, hyperuricemia.
2. CNS: anda ukozela, intloko, silale.
3. inkqubo yokujikeleza: megaloblastoz, thrombocytopenia.
4. GI: iintlungu esiswini, izilonda, amahlaba isisu, urhudo.
5. inkqubo yonyango: kwekhono erectile, carcinoma ibele, ivoti brutalization.
6. ziyabagulisa: ukurhawuzelela, irhashalala, ezindlwini.

Ukuba ngaba wehlelwa iimpawu kufuneka udibane nogqirha njengoko kuchaziwe apha ngasentla. Njengoko umthetho, yingcali ugqiba endaweni "spironolactone". Analogs kweli chiza kwakhona uneziphumo ebezingalindelekanga, kodwa ichazwa kangangoko engaphantsi.

oyi

Ngexesha unyango "spironolactone":

• Kuyanconywa ukuba ukuphepha ukutya ukutya zityebi potassium.
• Ngokungqongqo esalelweyo zonke iziselo ezinxilisayo.
• Kufuneka ayiyeke isicelo ngaxeshanye imithi kwi ekwakhiweni apho potassium ekhoyo.

Ukuba unyango sinikeziwe ngakumbi NSAIDs, kuyimfuneko ukuhlola ukusebenza kwizintso nezalathisi electrolytes egazini.

Kwisigaba sokuqala unyango kucetyiswa ukuba ayeke ukuqhuba iimoto kunye nokusebenza kunye neendlela ezinkulu ezifuna izinga eliphezulu reactions lengqondo ingqalelo. Ubude izithintelo ezinjalo ibekwe ngamnye, ngokusekelwe tolerability, "Spironolactone".

Ixabiso ichiza kunye neemeko yogcino

Iindleko ichiza yahluka ukusuka umthamo wayo. Kuba omnye diphu tablets kuya kufuneka ukuba uhlawule ukusuka engange-30 ukuya kuma-50. Kwakhona Indleko iyonke ixhomekeke eludinini, Nokubekwa imixokelelwane ezininzi ekhemesti.

Ngokutsho imiyalelo, ukulungiswa mazilondolozwe kubushushu na izinyuko ngaphezulu kwe-20, kude lendawo wezandla zabantwana. ezikhabhathini na iminyaka emi-3.

analogue iziyobisi

Ziziphi machiza indawo "spironolactone"? Analogs ye medicament kwiimeko ezininzi babe kuqamba efanayo kunye ingqalelo yecandelo engundoqo. Ezi zibandakanya ezi machiza alandelayo: "Veroshpilakton", "aldactone", "Veroshpiron". Le mali yamva amaninzi kusetyenziswa endaweni ingxelo kweli nqaku ichiza.

Phakathi amachiza afana nalawo ezaziwayo-kakuhle ziquka ezi zilandelayo: "Dekriz", "Inspra", "Espirit", "Epletor". Indlela yokusebenza afane "spironolactone". Iimpawu kunye bioavailability ezifanayo. Ezi womchamo zisebenza kakhulu ukuba kuqheleke uxinzelelo lwegazi, ukurhoxiswa ulwelo kwemfuneko emzimbeni. Noko ke, generic phantse ukukhusela ngokuchasene iziniki-potassium nezinki, Noko ke, oogqirha abaninzi bakhetha ukusebenzisa ichiza yokuqala.

Ngamafuphi

Ngoku uyazi phantsi izinto ezimbi nezidubedube kumisela 'spironolactone ". Ixabiso ichiza kunye nokufumaneka kwayo kwande - iinqobo emibini apho izigulane ezininzi ukhetha ngayo le medicament. reviews ezininzi HIV zibonise kakuhle kakhulu "spironolactone".