Prolactinoma posa: oonobangela, iimpawu, isifo kwaye afumane unyango. Ingqondo yebhinqa unoxanduva ntoni?

Xa umntu ebona libinzana lezamayeza inzima, iqalisa ibattery zibe kumacandelo yayo ukuze ukuqonda isifo zabo. Ngoko ke, umbuzo wakhe wokuqala kuwe ngu: "Yintoni uyahlangabezana yebhinqa?". Emva kokuba ukufuna olunzulu ulwazi ufumana ukuba le ndlala yonyango, elawula ukusebenza kwazo zonke ezinye amadlala emzimbeni. uphando kuya kukhokelela isigulane uluhlu eziveliswa emzimbeni zabo kunye namaziko target. Yaye kuphela emva kokuba isigqibo ekugqibeleni ukufumana oko kuthetha ibinzana elithi "prolactinoma yebhinqa." Le ithumba evelisa hormone kakhulu, umzimba ingaphatha kubo. prolactin abangaphezu kwemfuneko kunye ebangela iimpawu yezonyango iimpawu. Kodwa izinto zokuqala kuqala.

Yintoni na le ndlala yebhinqa?

Ingqondo yebhinqa unoxanduva ntoni? Posa - yinto yinxalenye ephakathi, kubekwe phezu carcinomas uluhlu ithambo, ebizwa ngokuba "undim Turkish." Le ndlala likhipha iihomoni elawula ukukhula kwabantu, isantya ukutya nokukotshwa lenzala. Posa - umbhexeshi le nkqubo yonyango. Ukuthetha ngxenye, kunye ziyayilawula umzimba, ngokubonelela imisebenzi yayo ebalulekileyo.

Xa ingqondo yebhinqa singamalungu ezintathu okanye izabelo:

1. lobe sobuKristu uvelisa iihomoni utshixelo. ngoko ke zibizwa ngokuba ezichaphazela amalungu athile kwaye iikhemikhali lumiselwe kwizihlunu zazo. Ezi ziquka:
   - ndlala nabanye hormone (ezinxulumene esinobubovu lengqula);
   - hormone adrenocorticotropic (lukwakhuthaza adrenal);
   - follicle-ekuvuseleleni hormone (ulawulo umsebenzi ngokwesondo, kunyanzelisa ekukhuleni oocytes);
   - luteinizing ihomoni (ivuselele ovulation);
   - hormone Growth okhulisayo;
   - hormone luteotrophic okanye prolactin (ilawula imbonakalo umthubi nobisi abafazi abakhulelweyo, linoxanduva ithuku koomama). Prolactinoma yebhinqa iyakhula nomhlehlo akudala, oko "onakalisa" umsebenzi hormone luteotrophic.
2. Le ngomva kwesibindi vasopressin secreted (noxanduva lokugcina eliqhelekileyo igazi engamanzi inyama noxinzelelo), kunye yioxytocin, apho kuyimfuneko kakhulu ngexesha lokukhulelwa nabongi umntwana. Esisebenza phezu umsipha egudileyo, kunciphisa nto.
3. I-avareji umyinge hormone kuhlelwe ezivuselela iiseli ulusu - melanocytes.

Imisebenzi njengoko kulula unokuthekelela, yebhinqa ezahlukeneyo. Ilawula division iseli kunye neprothini synthesizing ukwakha inyama entsha. Ukongeza, uMthetho nokuvuthwa kwamaqanda amadlozi, kwakunye impendulo komzimba hormone ngesondo. Uphazamisane amajoni omzimba ngokuvuselela okanye ziyibuyisela umsebenzi ndlala. Ilawula amanqanaba wegazi imithambo yegazi, isixa-mass ezityebileyo nomgangatho ubuthongo. Ingqondo yebhinqa ayifumaneki iiyure ezingama-24 ngosuku, iintsuku ezisi-7 ngeveki, bonke ubomi bethu.

Prolactin - ntoni na?

ukuqonda kangako nokwakheka amalungu yenkqubo yonyango, uyakwazi ukuqhubeka kohlalutyo yayo eneenkcukacha ngakumbi. Kakade ke, ngokukhawuleza, ngaphandle uqeqesho olulodwa akuyi kuba lula, kodwa ubuncinane uzame. Xa uxilongo, ukongeza kwi elithi "yebhinqa", kwaba sekunjalo prolactin. Yintoni na?

Prolactin - yenye hormone secreted ngokuthi iiseli acidophilic le yebhinqa sobuKristu. Kunye nesakhiwo sayo imichiza libhekisela kwizakhiwo protein. Izazinzulu bodwa ekhaya yonke kwezinto ukuba ezineempawu ezifanayo eziphilayo. Ezi ziquka:

- prolactin;
- proliferin (ulawulo division of iiseli zomzimba nokuqina);
- hormone;
- lactogen placental (secreted ngexesha lokukhulelwa).

Okwangoku eyaziwa iipropati prolactin ngqo okanye ezingathanga ngqo umsebenzi ngesondo kunye nokuzala. Ekujoliswe zomzimba, njengoko igama lichaza, eyona namadlala mammary. Hormone eshukumisa imveliso umthubi kunye nokuguqulwa wayo ubisi. Xa eshumini ngexesha lokukhulelwa inoxanduva ukukhula kunye nophuhliso kwamadlala mammary, inani lobules kunye imibhobho. Interesting nyaniso: I receptors ngokuba prolactin zifumaneka phantse onke amalungu kunye nezihlunu umzimba womntu, kodwa yintoni umphumo kubo akwaziwa.

prolactinoma yebhinqa kuvela ngenxa yemfuza kwi kwiiseli ze yebhinqa sobuKristu. Oku kuphakamisa imveliso ngokugqithisileyo prolactin akhuthaze iimpawu zayo, ochaphazela impilo-ntle kunye ukubonakala isigulane. Ngethamsanqa, isifo kwaye afumane unyango lwesi sifo sele uyabazi yaye avavanywe ngempumelelo, ngoko ke uxilongo - hayi isivakalisi.

prolaktinoma

yebhinqa prolactinoma ibhekisa isifo rhoqo nabungozi le yebhinqa sobuKristu (manani, 30 pesenti zonke yamathumba une). Common e namakhosikazi aselekhulile yokuzala. Umlinganiselo phakathi eyomeleleyo kunye besini enobulungisa - 1 ukuya ku-6.

Imilinganiso yalo, njengokuba umthetho, musa ukudlula milimitha ezimbini okanye ezintathu, kodwa amadoda ukuhlangabezana kunye nemfundo ezinkulu - ngaphezu isentimitha ubukhulu. Ezi yamathumba abo hormonally esebenzayo, njengoko ukuvelisa prolactin. Ngokuqhelekileyo oku kuhlanganiswa kuzo zombini namantombazane. Prolactin zinganefuthe abasemagunyeni ngokwayo okanye lidibene ne luteinizing kunye hormone follicle-inkanuko. Ingakumbi isenzo sabo luboniswa ngexesha lokukhulelwa kunye zisanyisa. Kodwa ngaphaya koko, ukulawula sexesheni kunye ovulation.

Ukusela hormone unalo nomkhwezeli. Wesifazane ie nenzalo awukwazi kumitha, uzale umntwana. Amadoda kufuneka titers eziphezulu prolactin abanengxaki amandla kunye uphawu ukwakhiwa ayinyani yaye ukukhula ibele njongo.

izizathu

Oososayensi yabona ngenxa ukuba kutheni umntu anazo a neoplasm, kodwa wabona ezinye iimpawu eziqhelekileyo, eqhelekileyo zonke izigulane unesifo onjalo.

Umbuzo wokuqala, Kakade ke, kukho ukuphazamiseka iziphene yemfuza kwinkqubo yonyango. Ngokuqhelekileyo, le neoplasia ezininzi (oko kukuthi, nethumba uye phantse zonke amadlala of secretion lwangaphakathi). Kukho imveliso elingaphaya prolactin, hayi nje kuphela, kodwa ke iihomoni yendlala kunye kwamadlala parathyroid, injeke, adrenal, posa kunye ubukho izilonda esiswini.

Yinto eyaziwayo ukuba izalamane ithuba ukufumana le ngezifo ingaphezulu kwe-avareji ngenxa labemi. yemfuza Modern akunikayo phezulu kwaye ufuna izakhi ukutshintsha iimpawu iiseli yebhinqa akudala, kodwa impumelelo ukuza kuthi ga kulo akakho.

ngezigaba

Yebhinqa adenoma (prolactinoma) ingahluka ngenxa indawo ngaphakathi sella. Yamathumba cell ukuba amaqela amabini:

1. Intrasellyarnye prolactinomas ukuba ingadluli sentimitha enye ubukhulu kwaye musa ukuya ngaphaya kwemida ithambo yebhinqa fossa.
2. Ekstrasellyarnye prolactinoma ezinkulu kanye banabileyo ngaphaya sella.

Ubungakanani nethumba kuxhomekeke ebukhulwini iimpawu. Oku kusebenza kuphela kwi intshukumo ethile hormone. Ukudumba ngokomthamo licudisa ezinye izakhiwo ingqondo, ibangela symptomatology luvo jikelele kunye focal. Oku ubumfama, ukuphulukana ivumba, ukulahlekelwa kwezinye luvo cranial (trigeminal, ubuso, oculomotor). Iimpawu oqhelekileyo intloko ebuhlungu, imo udandathekile, ixhala, ucaphuka kunye lability ngokweemvakalelo.

Prolactinoma yebhinqa: iimpawu kwabasetyhini

Kangangethuba elide, mfazi uqaphele utshintsho ezothusayo emzimbeni wakho, ingakumbi xa oko kufuneka, kwaye isifo ababenengxaki sexesheni. Xa izigulane waphawula ukuncitshiswa kwenani leentsuku esexesheni, yokunqaba netuwa okanye engekho wabo. Ladies abanqwenela ukuba umntwana akakwazi ukwenza njalo, ekubeni ovulation lungenzeki.

Ziziphi ezinye iimpawu kwenzeka amabhinqa? prolactinoma yebhinqa eshukumisa imveliso umthubi kunye nobisi, kwanabo besini ngobulungisa bangekakulungeli ukuba oomama. amathontsi alulwelo ukuze angakhululwa ucinezelo ngomatshini le ingono okanye isiqu yedwa (ngokuqhelekileyo ngenxa isixa esikhulu ubisi). Abasetyhini kunye ukubonakala ezi mpawu kwindawo yokuqala ucinga umhlaza webele okanye ezinye utshintsho zalapha, kodwa uviwo ngenyameko Ungafumana i ingcambu le ngxaki.

Iimpawu yebhinqa prolactinoma amabhinqa - ayikho kuphela ukhetho umthubi kunye nobisi, oku kwakhona ukwanda ubu ithambo ukuya ku kwamathambo. Ngaphezu koko, kusekho kwezinye iihomoni, ezifana estrogen ibangela ukugcinwa fluid emzimbeni, yaye ngokukhawuleza umzimba. Imbonakalo kutshintsha kakhulu - polymorphic amaqhakuva irhashalala, ukwanda hairiness kwi iindevu kwaye ezincotsheni ezindlebeni. Konke oku kufuneka athinte up embonweni kagqirha ngayo ithumba yebhinqa.

Iimpawu ezingabantu

yebhinqa prolactinoma emadodeni ibonisa ukuhla kumanqanaba testosterone kunye kakuhle iseli lwegciwane Ukwakheka. Loo nto nalo inzalo. Ke aspermia ezilahlekileyo akuvuki, kunciphise drive ngesondo, amandla kunciphisa.

Ukongeza, abameli kwisiqingatha eyomeleleyo wabona ukwanda kunye notshintsho imilo zamabele - gynecomastia. Ngokuqhelekileyo, oko kuqhelekile midlalo, ligxile iseti kwemisipha mass, yaye umntu akafumani steroid, kufuneka ibe ngumqondiso yingozi. Ngamanye amaxesha ngenxa incum ukwanda angase avuze ubisi.

Ukongeza, amadoda ekugqibeleni yoma kwamadlala ngesondo, abalinganiswa ngokwesondo zasesekondari angekhoyo, livela ubu ngokugqithiseleyo amathambo buthathaka kwezihlunu.

ekuxilongweni

Yebhinqa Ithumba (prolactinoma) Amaxesha amaninzi kumiselwa emva kokuba kugqitywe uviwo neuroimaging (iinkcukacha ngemagnethi livakale umfanekiso). Yaye nje ujonge shot obanzi, kwaye ifuthe yokukhangela yebhinqa ngezifo usebenzisa i arhente nshita - gadolinium, utshixelo neuroendocrine kwithishyu. MRI uyakwazi ukubona ubungakanani kunye nendawo nangezilonda.

Xa neentwana ithumba, ukuba sentimitha mnye, kuyimfuneko ukusebenzisa Itomography ngekhompyutha, ngenxa yokuba ulwazi ngakumbi. CT amathambo ibonakala ngokucacileyo kunye notshintsho kwazo ngexesha lokukhula adenoma.

Kodwa ukongezelela iindlela nezixhobo ezidingekayo ukuqinisekisa ngenqindi phantsi uxilongo kunye ukulungiselela utyando, kukho kwilebhu iindlela diagnostic. Olokuqala ukumisela umgangatho prolactin egazini. Uhlalutyo kufuneka wenziwe izihlandlo ezithathu, ngeentsuku ezahlukeneyo sexesheni kulawula imiphumela emibi lobuxoki-lobuxoki-HIV okanye zibangelwa luxinzelelo okanye eguquguqukayo nokomzimba. Isiphumo ebonisa nanograms ngaphezulu kwama-200 milliliter nganye, phantse nekhulu ekhulwini ibonisa ubukho ithumba.

Ukuba ngaba amanqanaba prolactin zazisuka nanograms-40 ukuya ku-100, kusenokwenzeka ukuba la manani zibangelwa ukuncipha umsebenzi lengqula, esifubeni kwentlungu, okanye kwekhono sezintso. Kakade ke, ezi zixilonga nazo abala-.

Uvavanyo thyrotropin kakhulu eziveza. Emva ulawulo emthanjeni xa kangangesiqingatha seyure kuye kwakho ukwanda prolactin. hormone xi ubuncinane kabini lokwaNdlalela. Xa izigulane prolaktinome ubungakanani prolactin egazini ayitshintshi okanye linyuke kancinane. Ukuba ukunyuka kwamanani okungaqhelekanga kwinqanaba hormone ayikho ngenxa ithumba, kunye nezinye izinto, zasabela thyroliberine uya kusondela eqhelekileyo.

Musa ukulibala ukuba kubhungisana neengcali ezinxulumene kunye imibuzo ngenyameko isigulane. Ukuze ngezifo umrhanelwa, ngamanye amaxesha kwanele ukubuza imibuzo efanelekileyo.

unyango

Unyango yebhinqa prolactinomas ngokuqhelekileyo amayeza. Amayeza ejolise ekunciphiseni amanqanaba hormone kunye neziphumo ezibi yayo sokulinganisa. Ukukhethwa amayeza kunye endocrinologist yazo idosi kwirejimeni lwenziwa kuphela phantsi kolawulo elabhoratri kwesifo. Xa isixhobo kagqirha kukho amayeza afana "Bromkriptin", "L-dopa", "Cyproheptadine", "Cabergoline" kunye nabanye. izigulane ezininzi kunceda abizwa ngokuthi "bromocriptine". Nomphumela obonakalayo ngaphakathi kwiiveki ezimbalwa. Kodwa yena a lot of ziziphumo ebezingalindelekanga, ngoko ukhetho engcono 'Cabergoline'. Ngaphezu koko, kulula ukuyisebenzisa (kwiiseshoni nje ezimbini ngeveki).

Uthomalaliso yancitshiswa ubungakanani ithumba, lo secretion of prolactin abuyele umbono eqhelekileyo, ayeke evuzayo ngumthubi. Xa namakhosikazi aselekhulile yokuzala lubuya esexesheni, umsebenzi enzala ibuyiselwe. Amadoda siyeke ukuba ludlolo, babuyele yobuntu.

Ukuba, emva kokuba ikhondo elide unyango ngendeb 'endala, imeko ayikatshintshi ukuba ngcono, okanye kukho ombi, lo neurosurgeon kunye endocrinologist ucinga ungenelelo yotyando. Izigulana Izimo ukuba kotyando, kukho enye - radiotherapy. Kodwa ethile: ukuphuhlisa yebhinqa insufficiency, yaye kufuneka therapy replacement ubomi.

Diet for prolaktinome yebhinqa ejoliswe ekunciphiseni umzimba, owayebonakele kwisiqalo ukuphanza hormone. Endocrinologist okanye nutritionist nga kunceda ukuphuhlisa isicwangciso isidlo eza nayo yonke olukhulu eziyimfuneko Micro elements, ngokunjalo abe umxholo omkhulu calcium phosphorus ezifunekayo yokuthintela kwamathambo. ukutya okufanelekileyo, unako unamathele nasemva sifo siya koyiswa.

Unyango amayeza intsomi yebhinqa prolactinoma akukho kakhulu ziingcali njengoko infusions kunye decoctions ningayingenisi yifuna, kodwa kwangaxeshanye zinqanda umsebenzi ndlala kunye adrenal. Oku kuchaphazela kakubi imeko yesigulane impilo, kwakunye iingqikelelo malunga kwakhona. Ukuba kangaka ufuna kusithuthumbisa ngokwam iiresiphi kamakhulu wakhe, musa ukulibala ukuba udibane nogqirha.

Ipredikshini kunye nokuthintela

Ngaba ndiya kuphila ukusuka prolactinoma posa? Ifuthe imveliso ngokugqithisileyo hormone mzimba kangangokuba, nokuba nethumba iphelile, abantu baya kuqhubeka ixesha elide ukufumana kwakhona imisebenzi elahlekileyo. Ukongeza, oogqirha abacingi iingqikelelo malunga nezinga ekuphulukenwe nalo nempumelelo unyango.

Iphinde ibuya malunga nesiqingatha izigulana kunye nasemva manani utyando are fana ephantsi - pesenti mathathu kuphela unyango.

Yeyona isivakalisi kwesifo "prolactinoma yebhinqa?" Izimali unike nzima. Unyango ingathatha iminyaka kwaye anike naziphi na iziphumo. Rhoqo, oogqirha bacetyiswa ukuba ukuthatha ikhefu phakathi izifundo amayeza ukuze bawubuyise nezintso nomhlehlo wesibindi. Kodwa ke ngaxeshanye, ukususwa ichiza kungabangela yobubi kunye ithumba nokukhula.

Izigulane ukuseka sesevisi zonyango kuhlolwa-up. ukuba ngamnye ngonyaka kufuneka wenze ikhompyutha okanye livakale magnetic ufaniso yobuchopho, dibana zamehlo, ugqirha kunye endocrinologist, kwaye ukuba bavavanyelwe inqanaba prolactin. Loo uviwo ngokucokisekileyo, uthelekiso ukusebenza ngaphaya kwexesha, kwaye hlengiso kwangethuba unyango kwenza kube lula ukwenza ezinye uqikelelo malunga kwakhona izigulane.