"Neostigmine" (kuqhume)

"Neostigmine" (iinaliti) sisiyobisi zokwenziwa, iyeza esebenzayo engundoqo leyo isebenza neostigmine methylsulfate.

Le amalungiselelo ngumsebenzi anticholinesterase ngokukhawuleza, ngoko ke emva ukusetyenziswa kwayo uphucula ukudluliselwa excitation ukusuka luvo ukuya isihlunu samathambo, nezibilini kwakunye iliso ikhulise zonke iziphumo cholinergic, nangenxa zinokukhuliswa motility zesisu, kwandisa nethoni inyumoniya, isinyi, amadlala yonyango kunye secretion.

Ukulungiselela "Neostigmine" kukhutshwa kuphela ngohlobo kwesisombululo ukuba isitofu, kodwa ngohlobo amacwecwe, granules, apho ulungisa lokunqunyanyiswa yomlomo (abantwana).

Ubungqina obubonakalayo buxela

Uthe medicament isetyenziswa phambi myasthenia, ukukhubazeka kunye paresis, ukuphazamiseka umsebenzi motor emva kokonzakala ingqondo, neuritis, kobuchopho emva, ipoliyo kunye tuberculous meningitis.

Kwakhona kusetyenziswa xa imfuno yonyango lwe optic luvo yoma, ukunciphisa uxinzelelo intraocular kuzo ukunyanga iglaucoma agalelwa siyandiswa, kwaye ukuba kuyimfuneko constriction ngayo umfundi. Kwezi zifo, ichiza isetyenziswa ngohlobo wamehlo.

Lithetha "Neostigmine" (iinaliti) isetyenziselwa yoqheliso zabasebenzi, kwaye isiphumo iintlungu. Amaxesha amaninzi ichiza isetyenziswa kunyango, apho ithathwa usebenzisa atony esiswini, lwesinyi namathumbu, oko kuthathwe ngomlomo.

"Neostigmine" izitofu kweziyobisi, kwakunye nezinye iintlobo ichiza, isetyenziswa kuphela ngokumiselwa, kunye nokuvumela iinkqubo zayo ezimeleyo abandakanywa vala.

Ukuba ichiza isicelo ngomlomo, umthamo yayo kuba umntu omdala ukusuka kwenye ekhulwini elinesihlanu grams hundredths kwaye wasiwa ka-3 ngosuku. Ngokuba abantwana abangaphantsi kweminyaka elishumi - omnye sewaka i gram kunyaka ngamnye olandelayo, kodwa akukho grams ngaphezulu kwe 0,01 ngosuku.

Ukulungiselela "Neostigmine" (iinaliti) unako kubhalwa zombini kwesikhumba kwaye intramuscularly xa isixa-1 ml isisombululo 0.05% yenziwa abantwana ngokutsho ml yeshumi kunyaka ngamnye, kodwa hayi ngaphezulu kwe-0.75 milliliter, bonke eyenziwa omnye okanye emibini amaxesha. Ubude lilonke unyango ixhomekeke nobungozi besi sifo kwaye inga ukusuka kwiintsuku ezili-15 ukuya kwezingama-40, kwaye kwezinye iimeko, ngeenyawo.

Xa kukho abasebenzi obuthathaka, ichiza "Neostigmine" (ampoules) kufuneka isetyenziselwe izitofu ongama , kwaye ngaxeshanye waqalisa njengendlela "Atropine". Oku kwenziwa kube kanye kuphela wokwamkelwa kokuqala ngqa okanye inaliti. Kwakhona, ichiza elo lilawulwa ngomlomo isixa 0,003 g onke amaxesha imizuzu engama-40 ukuya ku-6, kunye iinaliti wenza 0.05% isisombululo amaxesha 2 ilixa abaya kuthi ml 1.0.

Ukuze umntu omdala, idosi iphezulu ngemihla-0.05 g, yaye lo msebenzi kufuneka mayingagqithi elinesihlanu hundredths grams. Ngokumalunga lwezitofu, idosi iphezulu ngosuku ngu 0.006 g, idosi enye ye- akukho kumawaka ngaphezulu kwe babini gram.

ziphumo bezingalindelekanga kunokwenzeka

Emva kokuba isicelo uthe kuqulunqo kubonakale bradycardia, urhudo, isicaphucaphu, sinciphise uxinzelelo lwegazi, ukwanda secretion inyumoniya, ubuthathaka kunye negazi.

Ukuba umntu baba ukurhuda neentlungu esiswini, kwakunye umbilo ukugalelwa, libonisa nemiphumo ityhefu lithetha "Neostigmine". iziyobisi "Atropine" kwesikhumba ungabutofela kwiimeko ezinjalo.

Awukwazi ukusebenzisa amayeza phambi sokuxhuzula, ukwanda kwezihlunu, isifuba inyumoniya, angina, yegazi, basenokunganyamezelani kweli chiza.

Drug "Neostigmine": ncomo

Phendula kakuhle kule ukulungiselela abantu abaphethwe myasthenia gravis, njengoko lwenziwa ngoncedo unyango ukulungiswa rhoqo.

Umlinganiselo izigulane kwiziko "Neostigmine" luyathandabuzeka ukuba abanye bazenza izitofu rhoqo, ngoxa abanye baye babhenela besebenzisa kuphela izihlandlo ezinqabileyo, yaye ezinye Asikunyamezeli. Ngenxa effect icala, izigulane ezininzi phawula yimbonakalo nje umlomo owomileyo izinkcwe kakhulu nokuxutha izinto.