Kokubonisa yethishyu kwabantu

kwizicwili omzimba lomntu umahluko kusuka izihlunu osandul - mesenchyme. Xa inkqubo yale nkqubo yenguqu wenza izitho nezihlunu, apho kukho isakhiwo ezahlukeneyo kunye nenjongo. Xa inkqubo nokuqina ziquka umsipha egudileyo, nokuqina exineneyo evakalala kunye intlala izihlunu, iincindi zomzimba, olujikeleza.

inyama ezikhululekileyo nokuqina yakha capsule amalungu kunye nezihlunu. Iziseko eziphambili iiseli zomzimba nokuqina, amorphous nezakhiwo ezinezikhondo. Ubume bale iiseli kunye nemisebenzi yabo yahlukile kakhulu. Ipesenti ezona fibroblasts, leyo uthathe inxaxheba ekubunjweni kwiproteni, siphu- collagen, mucopolysaccharides. Kukho ezinye iintlobo ze fibroblasts ababandakanyekayo ekubunjweni Amalungu nezihlunu. It osteoblasts, chondroblasts, kunye nabanye. Le kwizicwili iqulethe macrophage, abathatha inxaxheba impendulo yokukrala kunye nokulungiswa izihlunu, reactions amajoni omzimba ekulweni izifo ezosulelayo amagciwane. iiseli Mast kukho zomzimba nokuqina kwasekwa kukuninzi ngexesha nangokurhala, cell mediators (histamine, njalo njalo).

Eyona nto - isiseko olumanyanisa iiseli zayo imicu. It iqulathe proteoglycans, polysaccharides kunye neeproteni. amatyathanga Proteoglycan eziqulathe hyaluronic acid, lweeHedfowuni, chondroitin sulfate. Hyaluronan igqiba amalaphu ndizayo permeability. izakhiwo ezinezikhondo luqulathe elastic imicu collagen.

imisebenzi
kwizicwili kuthatha umsebenzi ukuxhasa, ekubeni sisiseko amathambo, ulusu, kwaye amalungu stroma. Eli laphu liye amandla aphezulu kunye luthambe ngaxeshanye, ngenxa isakhiwo yayo ezinezikhondo.
umsebenzi Trophic kwithishyu kungenxa yokungena layo egazini, iimpahla nkovu komzimba. Proteoglycans inxaxheba kutshintshiselwano amanzi kunye neenkqubo pathways emzimbeni.

Zikhusela inyama nokuqina inikezelwa eluswini, inwebu kunye nezibilini njengezingxobo. umsebenzi Reparative kukuba ukuphelisa amandla umonakalo zomzimba nokuqina trauma, ukusabela arhabaxa.

isifo kwizicwili
Isiseko kwesifo kwizicwili luphuhliso yenkqubo zophendlo lwezifo kwi esikule ngokwayo okanye izithako zawo. Ekubeni yinxalenye amalungu amaninzi nezihlunu, izifo bayo bangonakala ngokwamaqela. Kuhlangene kwi etiological kunye pathogenetic siseko ukufana ukwenza izinto zonyango.

Iqela lokuqala rheumatism. Iqela lesibini liquka isifo ehlasela (lupus, scleroderma, Sjogren engqondweni, systemic isifo kwizicwili). Iqela lesithathu - a vasculitis zenkqubo. iqela Okwesine - isifo samathambo, samathambo namantshontsho. Ilandelwa ngu: spondylitis ankylosing, samathambo esosulelayo kunye osteoarthritis.

Izinto ezibangela izifo zomzimba nokuqina
Xa isifo nganye imiba yayo etiological. Kodwa izinto eziqhelekileyo lubandakanywe nezenzo kwizicwili zezi: a usulelo throat, Mycobacterium tuberculosis, i-arhente causative of gonorrhoea kunye negcushuwa, iintsholongwane yomkhuhlane, yimasisi. Asikabi yofuzo xa iziganeko zezifo lwenkqubo. Eyona nto ephambili kukuvela ezingaqhelekanga kukho iimpazamo nezifo. umonakalo lolwabo okubangelwa yokulahlwa kwe izakhiwo omzimba kwakheka ngenxa yezimvo amajoni omzimba ukuba sesichengeni eli arhente etiologic.

kubonakaliswa clinical
Kuba isifo esithile nganye luphawulwa obubonakala lwezonyango, kodwa kukho iimpawu ezifana ngazo. Le yikhosi elinenkqubela ixesha elide sifo, ixesha febrile, isifo edibeneyo, ukwehla kobunzima, umzimba ezifana ukusabela, utshintsho ngegazi amaqhezu protein, ngokoyiswa ulusu, iziphumo ezidibanisayo ukusuka ukusetyenziswa kweziyobisi hormone.