Giant cell thumba: unyango nabanye abantu abane

Giant cell Ithumba - isifo efanayo oncological, apho amaninzi ezehlela abantu abaneminyaka eyi-15 ukuya kuma-40 ubudala. Isifo iphawulwa ikhondo nabungozi, kwaye ngoku nethumba senziwa ijwabu ithambo.

Kwelinye icala, phantsi kwempembelelo kwezinye izinto yeenguqu kunokwenzeka ingozi, nto leyo naxa ingumbandela ozaliswe ziziphumo eyingozi. Ngoko ke yintoni eyenza isifo kwaye oko yayingako imiqondiso kufuneka sinikele ingqalelo kuyo?

Yintoni osteoblastoklastoma? iimpawu zezakhiwo

Giant cell Ithumba isakhiwo kakhulu ezithile, nto leyo senziwa ithambo. Yinto eyaziwayo ukuba osteoblastoklastoma luqulathe iintlobo ezimbini iiseli: mononuclear encinci (iiseli ngeenxa okanye elimbhoxo kunye engundoqo eqaqambileyo kunye encinci chromatin) kunye multinucleated ezinkulu (20-30 ziqulathe nuclei kwaye ziyafana osteoclasts eqhelekileyo, ukuba ngokufanayo asasazwa Ebubanzini kunye neoplasms zisekhusini ukusuka komunye).

Kulo mxholo kunokubonwa ukuba ngaphakathi inwebu ithumba ezitofotofo na umbala omdaka kunye nentwana elincinane legazi (ukopha) kunye necrosis.

ngezigaba yamathumba

Xa yesilungu, neoplasms ezinjalo zihlelwe kuxhomekeke kubume, imilo kunye nezinye iimpawu. Ukuba sithethe malunga iimpawu lwesakhiwo, iseli ithumba isigebenga ingaba:

• nylon (yakhiwa iiseli ezincinane, ezahlulwe izahlulelo ithambo ayiphelelanga);
• esinganyangekiyo (Ithumba umngxuma ithambo, oko izaliswe elulwelo, ngoko ufana cyst);
• lytic (lolu hlobo lokukhula ithumba silwe sikhatshwa intshabalalo ngokukhawuleza wethambo; ithambo ipatheni ethile ayikwazi ukucaciswa).

Ngelo xesha loxilongo, uhlawule ingqalelo neoplasms indawo. Ithumba inokuba abe ngundoqo (eziveliswa ithambo ziyatyeba) okanye peripheral (ezichaphazela isakhiwo komhlaba kunye periosteum ithambo).

Malunga nama-50% amatyala nethumba ise ancedisana wethambo ngeenxa entlanganweni kwedolo. nethumba afunyanwa rhoqo kwi radius distal. Noko osteoblastoklastoma inokuchaphazela phantse naziphi amathambo, kubandakanywa amalungu omqolo, sacrum, lesiquluba, yifemur kunye ihumerus, emhlathini asezantsi. Ngamanye amaxesha inkqubo zophendlo lwezifo wayengabalibali imisipha kunye inyama ithambile.

Eyona eziphambili ezibangela izifo

Ngelishwa, ukuza kuthi ga ngoku, izizathu ukuvela ukukhula Ithumba ayaziwa. Kukholelwa ukuba kukho into ilifa, ingakumbi xa isiseko okanye uphuhliso izixhobo amathambo komntwana ukususela ekuqaleni wahamba ngendlela eyiyo.

Ezinye iingcali zithi amathuba kuphuhliso giant ukunyuka iseli ithumba ukuba isigulane waba sisifo yokukrala ezichaphazela ithambo kunye periosteum. Imiba yomngcipheko nazo zibandakanya Ukophuka rhoqo kunye nezinye ukwenzakala izixhobo inkxaso.

Ziziphi iimpawu kufuneka sinikele ingqalelo kuyo?

Xa sikwinqanaba lokuqala lophuhliso giant cell ithumba azifane uzenza ngayo. buhlungu ngile kunganxulunyaniswa ngemiqondiso yokulumkisa kwangethuba ezivela amaxesha ngamaxesha. Iimpawu ezibalaseleyo kakhulu zesi kwenzeka ngenxa yokwanda kakhulu a neoplasm.

Bone inyama iqala ukubola. Kukho Ukophuka ezikhululekileyo kwindawo yamathumba zalapha. Njengoko ukukhula nethumba phantsi kwesikhumba elivelayo mbile, ngamanye amaxesha kunye lichaza ezibukhali. On the integument kwi sisilonda esidumbileyoesingaphakathi ingqalelo iimpahla Mesh.

Ukuba Ithumba ifumaneka kufutshane joint, kusenokubakho buso okanye epheleleyo ilahleko ukuhamba kwayo. Bomzimba kwakhona ucaca ngakumbi - ukuqaleka endibulala nomonde ngexesha imithambo ukuphumla.

inkqubo okubulalayo iimpawu zayo

Giant cell Ithumba of ithambo luthathwa ukukhuseleka kakhulu. Noko ke, kukho usoloko unomngcipheko yotshintsho elinobuhlungu yamathumba. Ukuza kuthi ga ngoku, oonobangela ngqo engabangela inkqubo ayaziwa. Ezinye izazinzulu zikholelwa ukuba ityala yonke into - utshintsho hormone kunye nokwenzakala rhoqo. Kukho noogqirha bathi ngokutsha sisiphumo radiotherapy odlulileyo.

Xa kunjalo kubalulekile ukuqonda ukuba umhlaza kuyingozi. Hi ndlela leyi, inkqubo sikhatshwa eziliqela iimpawu ongcono ukuhlawula ingqalelo. Kubekho ukukhula ngokukhawuleza yemfundo. Amaxesha amaninzi inkqubo yezifo lingaphezu ithambo - kwiimeko ezinjalo ukhandwa giant iseli ithumba yethishyu ethambileyo okanye imicu.

Ngexesha uvavanyo, ungafumana phambi utshintsho kwisakhiwo nangezilonda - iba ibhulorho lytic, ithambo phakathi kwiiseli iphela, isithunzela iqhuma esinganyangekiyo fifi. Ukwandisa ububanzi we sisilonda - ukugula ephelekwa intshabalalo olunzulu esiqwini ithambo.

inkqubo yoxilongo lwezilwanya

Ubukho abo okanye ezinye iimpawu abachukumise phezu ugqirha ingcinga yokuba nomhlaza. Kakade ke, giant iseli ithumba kufuna diagnosis ngenyameko. Emva anamnesis isigulane emiselweyo:

• Uhlalutyo ezinto igazi, ongayi kuphela khangela umzimba uphela, kodwa kananjalo ukubona ngabamakishi ebonisa ukutshatyalaliswa ijwabu ithambo.
• Kunyanzelekile x-reyi. Emifanekisweni ugqirha uyakwazi ukubona ithumba, ukuvavanya ubungakanani bayo, ukuhlola imeko amathambo. Izixhobo moshilongo loo iyafumaneka phantse zonke esibhedlele, kwaye iindleko zonyango ezikhoyo.
• Eyona ndlela kakhulu ulwazi na iinkcukacha ngemagnethi livakale umfanekiso (iziphumo ezichanekileyo ngokulinganayo zingafumaneka kusetyenziswa Itomography ngekhompyutha). Ugqirha unethuba ukufumanisa ubukhulu kunye nolwakhiwo ithumba, ukuhlola imeko inwebu ithambo, ukuze ubone metastases ezikhoyo. Ngelishwa, akukho uphando luyabiza.
• Xa efumanise biopsy ithumba kuyacetyiswa. Ngexesha inkqubo, ugqirha owenza ijwabu isampuli evela neoplasms - zikhohlela zimbini ke zithunyelwa elebhu. Uhlalutyo biopsy kunceda ukuba utshekishe ukuba ngaba iiseli ithumba.

Ngokusekelwe kwezi data ugqirha uyakwazi ukubona ukuba ithumba eyingozi, uze ukhethe unyango kakhulu olusebenzayo.

Giant cell Ithumba: unyango

Ngoko nangoko ke paha ukuba unyango ixhomekeke kubungakanani nangezilonda, ubukho inkqubo onobungozi, indawo metastases, njalo-njalo. D.

Ukususwa giant cell Ithumba kuyimfuneko. Ngexesha kotyando, resection olwenziwa nangezilonda nje kuphela, kodwa kwisiza amathambo ochaphazelekayo. Ukususa inxalenye izixhobo inkxaso endaweni sokwenziwa. Xa nezilonda okanye usulelo ithumba ugqirha usenokugqiba ekubeni okwalandelwa mlenze yonke. Ukuba metastases (umz, umphunga okanye isibindi) zabonwa emzimbeni yesigulane, ngoko ukususwa inxenye yazo ikhutshwa kwizihlunu abachaphazelekayo.

Lidla kwisekethe watshintshela radiotherapy. unyango olunjalo kuyimfuneko Kwimeko yokuba thumba ayisuseki (umz, oko amiliswe ngaphakathi yifemur, vertebra okanye sacrum). Zokukhanya oluqhutywa kukho inkqubo onobungozi, kwanokuba ngexesha kotyando wakwazi ukuphelisa zonke izinto ezakhiwe zophendlo lwezifo. Kwezinye iimeko, izigulane ngabom akwavuma resection ithambo.

Ukhetho unyango kuyimfuneko ukuba uthembe ugqirha. Kuba unyango lwe osteoblastoklastomy isicelo ekude gamma-unyango, radiotherapy orthovoltage, elekhtrons okanye radiation electron.

Giant cell Ithumba: i-ALS izigulane kunye nezigulo kunokwenzeka

Kwiimeko ezininzi, ukuba nesimo sengqondo esihle kwizigulane. Kakade ke, kufuneka asuse ithumba, badla kunye inxalenye ithambo achaphazelekayo. Kodwa likakade abhalwe kungeyonto ayenza rhoqo.

Kodwa ebulalayo giant iseli Ithumba kunengozi, ngenxa yokuba esi sifo ihamba ukuyilwa metastases, ezinokuthi zilungiswe ngayo phantse naliphi na iziko likarhulumente. Ugqirha akusoloko kusenzeka ukwenza resection zonke yamathumba.