Cromoglicic acid. Inkcazelo, ekhomba, Izimo

Yintoni kromoglitsievoy acid? Oku uya kufunda kwezi zinto zokufunda kubonelelwe ngazo nqaku. Siya kunixelela ukuba malunga apho amayeza ziqulathe iziyobisi bathi kwaye limela.

ifomu ukukhululwa, inkcazelo

Cromoglicic acid yaveliswa inkonxa ngenxa inhalation, ukutshiza ngeempumlo, wamehlo nakumarhanana zokutshiza. Kwakhona esi sixhobo zingathengwa ngohlobo kwesisombululo ecacileyo njengezingxobo kunye ngumgubo, ibiya inhalation.

Umgaqo ekusebenzeni medicament

Cromoglicic acid, ixabiso yayo eboniswe ngezantsi, omeleza imifinya iseli lwemasti, kwakunye zimise zazo. Oku kungenxa kuvalwe iindlela yokungena calcium ukungena kwiiseli.

Kufuneka kuqatshelwe ukuba le arhente abangaphangeliyo ukukhululwa yabalamli nokwaliwa ezifana leukotrienes, histamine, kunye nezinye SG2, ngeeseli ezahlukeneyo, abakulo isifo le mithambo ye bronchi kunye nomthi inyumoniya. Ukongeza, le nto inceda ukucinezela yokufuduka monocytes kunye neutrophils.

izakhiwo

Cromoglicic acid liveza iimpawu zilandelayo:

• ziyasebenza nokuthintela ngokukhawuleza uhlobo nezidlo kubantu abatsha, nabangekafumani kwabonakala utshintsho ezingapheliyo ayibuyiseki umva kwi kwemiphunga. Kufuneka kuqatshelwe ukuba into wathi ayenziwanga kuphuhliswa khipha bronchospasm.
• ukusebenza inwebu-ozinzileyo nemiboniso. Inkqubo ye ziyibuyisela pulmonary impendulo umlamli lunceda ekuthinteleni kuphuhliso ukusabela kwangethuba kwisigaba kade abanesifuba (kuquka ukuphendula omzimba kunye nezinye nokushukunyiswa).
• ukusebenza ezinzileyo yokusetyenziswa iyeza iyazalisekiswa emva kweeveki 2-4. Isiphumo ichiza emva kulawulo olunye apho iiyure ezi-5.
• iziphumo olubonakalayo lwe unyango lwezifo kunje ngamalungu ezibonwayo lwenzeka emva kweentsuku nje ezimbalwa okanye iiveki.

• ukusetyenziswa elide ichiza kunciphisa nezihlandlo ukuhlaselwa sombefu inyumoniya, kwaye ibhexesha kakhulu kwikhondo labo, kunciphisa imfuno ngokuthatha corticosteroids kunye bronchodilators.

kinetics

Cromoglicic acid etsalwe iphecana sokuphefumla xa isixa-mali ka-10%, kwaye emva inhalation of medicament ibe luthuthu isisombululo - 5-15% ne-8% ngokulandelelana.

Sokufunxa evela imifinya yokuphefumla yangaphakathi kunciphisa xa isixa secretion. Le xi liphezulu iziyobisi iyazalisekiswa emva kweyure ¼.

Esi sixhobo ayikho umzimba. Bawo-ubomi imizuzu 45-90. Isiphumo ngayo ngokusebenzisa amathumbu kunye nezintso kusenziwa ngokwemilinganiselo malunga ngokulinganayo, kwakunye nge emiphungeni.

ulawulo Intranasal kumlanjana igazi lifumana malunga ne-7% ye kuqulunqo. Kunye iiproteni plasma sibopha ukuthi 65%. Xa oku sixhobo na umzimba kwaye kwazona kwi enyongweni izintso ekwimo ingaguqukanga ngaphakathi iiyure enesiqingatha. Inxalenye into esebenzayo kufincelwe ngaphandle nokufunxwa kwaye yabelwa yi iphecana zesisu.

ubungqina

Kuncipha kuba amehlo Antiallergic elawulwa kunye conjunctivitis komzimba, keratitis negazi, keratoconjunctivitis, eyomileyo iliso syndrome, uhlobo, ukudinwa iliso isifo ubuhlungu amalungu ezibonwayo ziyabagulisa.

Kufuneka kuqatshelwe kanjalo ukuba esi sixhobo isetyenziselwa nokuthintela sombefu inyumoniya, bronchospasm kunye iphika ezingapheliyo kunye BOS syndrome.

Ichiza yimilo-arhente ngeempumlo ekucetyiswa ukuba hay fever nokuthimliswa komzimba.

Izimo

ichiza kujongwa ungamiselwanga ukuba:

• hypersensitivity;
• ukukhulelwa (ezintathu yokuqala ye inhalation);
• kubantwana (ukuya kwiminyaka emibini - ngokohlobo lomgubo kunye njengezingxobo ukuba isisombululo inhalation, oneminyaka emi-5 - ngokohlobo inkonxa ngenxa inhalation kunye nolawulo intranasal);
• ibele (yolawulo intranasal).

Kromoglitsievoy acid: umyalelo

Inhalation iipilisi ze inhalation kufuneka lwenziwe kusetyenziswa spinhalera amaxesha-4 ngemini ngamathuba iiyure 3-6 (20 mg).

Ngomgama ithamo inhalation zetoti elawulwa ithamo 1 (1 mg) kane ngemini.

Solution for inhalation usebenzisa inhaler ngokusebenzisa (20 mg) kane ngemini. Ngaphambi usebenzisa ibhotile izanyazanyiswa ngononophelo kwaye zigcinwe kwindawo tye.

amathontsi Nose elawulwa abadala ethatheni nganye 3-4 lihla ngeeyure 4-6, nabantwana kwiminyaka emi-6 - qho kwiiyure 6 1-2 amathontsi. Emva kokuba ukubonakala isiphumo zonyango bekhefu phakathi amathamo ichiza nga ngcembe ukwandisa.

spray ngeempumlo isicelo ithamo 1 ngeempumlo Kakade 4-6 nganye kathathu ngemini. Ikhosi ye unyango ziiveki-4. Ukupheliswa kwe ichiza kufuneka wenziwe ngokuthe ngcembe ngeveki enye.

wamehlo (umz: "cromoglycate Isiqalelo setyuwa") usebenzisa 1-2 lihla kwiliso nganye amaxesha amane umzimba ngemini kudluliswe iiyure 4-6. Ukuba kuyimfuneko, eli nani lanyuka ukuya instillation ka 6-8 emanzini.

imiphumela emibi

Isifundo kungabangela:

• isiyezi, isicaphucaphu, nokopha;
• ukuluma kwaye kome emqaleni, intloko ebuhlungu, umlomo owomileyo, ukugcinwa womchamo;
• usi yokuphefumla, ukuxinana ngeempumlo, ukukhohlela, ukutshisa yamehlo, umsebenzi kidney kakuhle, ukwanda secretion of netuwa ngeempumlo;
• irhashalala eluswini, nokudumba conjunctival, iliso owomileyo, mnandi incasa imvakalelo, amazwe imvakalelo umzimba, nerhasi, lacrimation;
• anaphylaxis (kubandakanywa nzima igwinya, isikhumba sakho silume, ochazwa kweenkuku, izigxala, ukudumba komlomo, ubuso iinkophe, bewuhlisele uxinzelelo lwegazi, ukuphelelwa umoya).

Izifanokuthi kunye nexabiso ichiza

Phantsi igama lorhwebo wathengisa kromoglitsievoy acid? Oku "Ditek", "isodiyam cromolyn," "Ifiral", "Intal", "kromogeksal", "Kromogen Easi-Phefumla", "Nalkrom", "Kromogen", "Kromoglin", "Kromosol", "Cromolyn", "Kropoz "" Lekrolin "," Kuzikrom "," Stadaglitsin "," Hi-chrome ".

Ixabiso indlela inokuba ezahlukeneyo, ngokuxhomekeke umenzi, uhlobo ichiza kunye network ekhemesti. Nangona kunjalo, i-avareji yeendleko kromoglitsievoy acid yi 100-250 engange.