"Valz": imiyalelo ukusetyenziswa, kunye nohlaziyo ukufunda. Analog "Valza" cheap

umfutho wegazi - sisifo izigidi zabantu ngexesha lethu. Iminyaka emininzi, sisungule amakhulu iziyobisi ekwaziyo ngokukhawuleza kwaye kwithuba elide ukusombulula ingxaki yokwanda wegazi, ingakumbi yingozi apho kukho ingxaki unesifo ikhawuleza kakhulu kungakhokelela ukopha stroke kunye nokufa komntu kunokwenzeka. Ngelishwa, zonke izinto ezinokuthi unokusinyanga, ukuba iqondo elikhulu okanye elingaphantsi kwaye kunganobungozi. Oku kuyinyaniso ngokukodwa iziyobisi, xa iziyobisi ingakumbi "Valz" echaphazela yonke emzimbeni wonke. Ngoko ke, ngamanye amaxesha kuyimfuneko ukuba pick up analog "Valza" ukuba akukho ezifanelekileyo ezithile parameters.

Inkcazelo yokulungiselela

Le medicament alahlwa ngohlobo mbhoxo iipilisi biconvex umboniso isale imingcipheko kunye kwicala-V ibhalwe ngaphezulu omnye. Umbala kuxhomekeke kwisiqulatho isithako esebenzayo. Yellow ibonisa ubukho 40 okanye 160 mg valsartan kunye pink ingqamana 80 mg esisebenza.

Awona macandelo abancedisayo ziquka monohydrate lactose, microcrystalline kwincindi, isodiyam croscarmellose, nemagnesium stearate, povidone K29-32, talc kunye colloidal lesilicon dioxide.

elapha

Ukulungiselela "Valz" libhekisela vasodilators peripheral, ngamanye amazwi, kwandiswe imithambo yegazi, kukhokelela ekuncipheni uxinzelelo lwegazi. Le effect kungenxa esisebenza - valsartan ukuba blocker oluthile angiotensin II AT1 receptor ngaphandle ziyibuyisela ACE ngaphandle kokuchaphazela isixa cholesterol iyonke, izikhombisi kwinqanaba iswekile, uric acid kunye triglycerides.

Isiphumo ephambili ivela emva iiyure ezi-2 emva kokuba ukusetyenziswa kweziyobisi, efikelela kangangoko ngamaxesha 4-6. Isiphumo therapeutic uyakwazi kuthatha iiyure ezingaphezu kwama-24. iipilisi rhoqo kukhokelela yindikhathaza kakhulu ukwehlisa uxinzelelo lwegazi emva kweeveki 2-4. Ukuba ufuna ukumisa kabukhali mali ukutsala anayenza.

indlela isenzo

Emva ulawulo ngomlomo kuza kukufakwa nkqi ukwimo esebenzayo kwi imvelaphi namaqondo awohlukeneyo sokufunxa. figure bioavailability Absolute yi-avareji ye-23%. Emva ulawulo ngomlomo, sibopha kwiiproteni plasma phantse 97%. Njengoko imbangi yokuba angiotensin II, iyeza esebenzayo ebangela ukwandiswa emithanjeni egazini, nto leyo ekhokelela ukuhla uxinzelelo egazini. Ichiza kusingathwa yi inkqubo transcriptase ethile iiyure 9 uze imveliso kwi-70% kwi-wamathumbu, no-30% ngokusebenzisa ifomu kwenkqubo maloizmenennoy womchamo.

Ulawulo idosi enye yemihla ngemihla kukhokelela olwenzeka kancinane kakhulu into esebenzayo emzimbeni.

Ubungqina obubonakalayo buxela

Ukulungiselela "Valz H", nto leyo analogue yayisalawulwa ezimbi efanayo, esebenzisa:

• koxinzelelo lwegazi oluphezulu;

• Ukungaphumeleli intliziyo ezingapheliyo njengecandelo zonyango ezintsonkothileyo;

• emva iqhosha etsolo engabalulekanga (ibhalwa kwixesha ukusuka kwiintsuku ezili-12 iiyure ku-10), nzima lubandakanywe nezenzo ukusilela ventricular ngasekhohlo, ventricular ekhohlo iSystolic kwekhono kwinqanaba imvelaphi lozinzo hemodynamic.

Izimo

Analogs "Valz" kweziyobisi, njengoko akayi wesakhiwo sedata besisetyenzisiwe:

• e hypersensitivity ukuya esisebenza okanye izinto abangabancedani;
• enokuphazamisa kwesibindi (ingakumbi kuphuhliso cholestasis okanye kwesibindi biliary);
• kunye ezinxaxhileyo kwi iintlobo ezahlukeneyo ukusebenza sezintso;
• kumanqanaba ahlukeneyo lokukhulelwa ngexesha lokuncancisa;
• kubantwana abancinane ngaphezu kweminyaka eli-18;
• xa ngenxa galactosemia galactose malabsorption nokunganyamezelani lactose.

uxinzelelo lwegazi Low, ukungabikho umxholo kumzimba sodium kunye potassium, mabili sezintso kwimithambo stenosis, stenosis aortic kunye mitral, cardiomyopathy kunye hyperaldosteronism lokuqala zifuna ukusetyenziswa ngononophelo ukulungiselela "Valz". nucleoside Russian nayo iinkalo isicelo ezifuna iingcebiso zeengcali ngenjongo unyango ekhuselekileyo.

effect side

Njengayo nayiphi na inkqubo, iziyobisi "Valz" kunokubangela eziliqela iziphumo ezingalunganga ukusuka amalungu ahlukeneyo:

• ukungaqheleki iimpahla intliziyo igazi ukubonisa hypotension intolerance, kunqabile vasculitis iphuhlisa ngokwaneleyo, maxa wambi kukho ukopha;
• kunokuba Akuvamile kukhokelela ezingaqhelekanga kwinkqubo yokuphefumla, ebangela reflex ukhohlokhohlo;
• maxa wambi kusenokubakho urhudo, kunye neentlungu esiswini;
• nefuthe elibi luvo lunokwenzeka vertigo postural, syncope, sokulibala, neuralgia okanye ngamanye amaxesha yintloko;
• neutropenia kunye thrombocytopenia ngamanye amaxesha;
• ziyabagulisa;
• ubuhlungu okanye kwemisipha inkantsi umva, kwakunye samathambo kunye myalgia;
• kaninzi ichiza ithande ukuba buthathaka zokuzikhusela zomzimba, iyenza basengozini amagciwane (sinusitis, pharyngitis, conjunctivitis);
• kunqabile ukuba kuvela imvakalelo chronic fatigue, asthenia, nokudumba.

Okubonakalisa le miphumela ingafuna thethwano kunye nogqirha wakho ukuze ukhethe amachiza-analogu "Valz."

Idosi isicelo yesekethe

Uthathela iipilisi kunye umthamo ezaneleyo ulwelo, kungakhathaliseki ukuba ukutya. Oyidlayo kuxhomekeke isizathu ukusetyenziswa, ekubeni ichiza "Valz H" analogs "Valsakor" "Valsartan," "Valz" kunye nabanye zinokusetyenziswa kuphela lwemithambo lwegazi.

tablets yaphathwa ne nedosi ye-mg 80 (ixesha kunye nexesha yonke imihla) ukunciphisa uxinzelelo lwegazi. Isiphumo therapeutic ngexesha elifanayo ngcembe kunyusa ngexesha Kwiiveki ezimbini zokuqala, lwathi ukutyhileka liphezulu emva ikhosi inyanga. Ukuba le ithamo alusebenzi, oko kwandiswa ukuya mg 160 ngosuku, ngokuba unyango olusebenzayo ngakumbi ukuncedisana womchamo. Analogue "Valza" - ukulungiselela "Valz N" - ayifuni ulungelelwaniso enjalo, njengoko sele kumafa yayo, ukongeza valsartan esisebenza kunye umchamo hydrochlorothiazide.

Ngophuhliso sisifo sentliziyo esinganyangekiyo (CHF) unyango uqalwe nge umthamo we-40 mg ngokuyinika amaxesha ayo 2 ngosuku. Ukuba ziphumo zinqwenelekayo ithe waphawula, isigulane idluliselwa "Valz 80" - analogu "Valz 40" iziyobisi kwakhona kabini mihla yokwamkelwa kwabafundi (ithamo ubuninzi - 320 mg ngamanyathelo ezimbini). It zinokudityaniswa kunye nezinye ii-arhente ekujongwe ukoyisa ukusilela intliziyo ezigulo ezondeleyo.

Ngokuchasene imvelaphi iposi engabalulekanga kwinqanaba ezinzileyo yokumpompoza kwegazi unyango valsartan ingaqalwa kwiiyure ezili-12 emva kokubanjwa okanye imeko ahlekise. Yabela Le tablet isiqingatha "Valz 40" kusasa nangokuhlwa, ukwanda ngcembe (iiveki eziliqela) phambi kokuba ithamo 160 mg kabini ngemini, acandacanda umthamo 40 no-80 mg, ngokulandelelana. Okuhlenga ngelixa kwi imeko yomguli, inqanaba nokunganyamezelwa amayeza abo. Emini umthamo mg 80 ukuvelisa kwiveki yesibini ka unyango, ekuphumezeni ithamo of mg 160 ukwimo esebenzayo ekupheleni kwenyanga yesithathu unyango.

Izigulana ezingaqhelekanga kwi kidney, kodwa KK lingaphezulu kwe-10 ml / min, ulungiso idosi kwenziwa. Izigulane ukuba ukukhanya kunye nowobulali umsebenzi wesibindi ukungaqheleki (ngaphandle cholestasis, obonisa ukulungiselela "Valz" analogs Russian ngolwasemzini, akukho kuboniswe), idosi avumelekile yemihla ngemihla ichiza isetyenziswa ukuya ku-80 mg esisebenza.

Iimpawu ze isicelo

Ekubeni ondoqo Izimo kunye neziphumo ebezingalindelekanga ngokwaneleyo, kufuneka isetyenziswe zizazi, behamba ngayo yonke iingcebiso ugqirha ngokubambelela ngqo idosi emiselweyo, ingakumbi xa kukho izinxaxhi emsebenzini namanye amalungu kunye neenkqubo zomzimba.

Ukuba ogulayo sodium imibala ngokukhawuleza, kudityaniswe ekuthotyweni BCC (elinokuba ngenxa yokwamkela inani elikhulu womchamo), unyango kunye "Valz H" (analogu "Valza") kunokukhokelela uxinzelelo lwegazi drop ngelo kanye ekuqaleni konyango eza kakubi kwimpilo yesigulane. Ukuze uphephe oku isiphumo phambi ingxaki enjalo, ukuba kuyimfuneko phambi kokuba ukusetyenziswa kwezi mali ukuze abuyisele amanqanaba electrolyte kunye nomlinganiselo yabo emzimbeni.

Xa renovascular xi ephakamileyo type imilinganiselo mfuneko rhoqo inqanaba urea kunye creatinine.

Co-ulawulo neziyobisi potassium okanye ityuwa yalo kwakunye arhente lilungu womchamo potassium-ungayekwa, ufuna rhoqo esweni umxholo potassium kwi plasma.

Ukusetyenziswa ichiza "Valz 160" analogs leyo kule sifo nto wabelwa ukuba unyango kwezigulane ukusilela intliziyo, kunokubangela ukuhla uxinzelelo yegazi Kudinga kokusebenza kwalo.

Kuba izigulana elinye okanye amabini sezintso kwimithambo stenosis, kuyimfuneko ukuba kubekho ukujongwa rhoqo urea igazi nitrogen kunye creatinine in serum.

Ngexesha unyango nale amayeza kufuneka ukuba ziqaphele izithuthi zokuqhuba kunye neminye imisebenzi, okuthetha ukunyuka yoxinaniso ingqalelo nesantya yokusabela.

Ukukhulelwa ne zisanyisa

Ukusetyenziswa kumacwecwe 'Valz "ngexesha yokumitha ibele ngokupheleleyo contraindicated. Oku kungenxa yokuba izifundo kwi ifuthe valsartan ekukhuleni kosana olungekazalwa azikhange kuqhutywa. Noko ke, kukho uluvo lokuba ngenxa iimpawu perfusion ezingekazalwa kwezintso, leyo ixhomekeke lokusekwa kwenkqubo renin-angiotensin, uqalisa ukusebenza kuphela ezintathu zokugqibela zokumitha, into engena egazini we umbungu kunye nempembelelo embi kuye, ingakumbi ngexesha ezintathu yesibini neyesithathu. Ngoko ke, ziziphumo ukukhulelwa kubonisa ukuba unyango wokucinywa "Valz" iziyobisi. Analogs, ukubuyekeza unyango ezintle, abuthe kuba abafazi zikumanqanaba ahlukeneyo sokukhulelwa, ukuba ugqirha kuphela. unyango Sanele uya kuvumela, ngaphandle ebangela umonakalo ndingekazalwa, ukunceda isigulane ukoyisa ubunzima.

Uphando kwii-isithako esebenzayo ngobisi lwebele yaye akubanga njalo xa kuthe kwiimeko ezifuna nokuqeshwa iziyobisi ukunciphisa uxinzelelo lwegazi ngethuba xesha lokwaphusa, kuyimfuneko ukuba benze ukhetho phakathi ukurhoxiswa unyango kunye ukumisa nokuncancisa.

libanda

Bobude amathamo yokwakha okanye ukwabelana ngokungafanelekanga yeendidi ezahlukeneyo iziyobisi kungakhokelela libanda, nale nto. Kubonisa isimo ukuncitshiswa ephawulwe of wegazi, ukuya ekulahlekeni sezingqondweni yokuwa.

Unyango liye lancitshiswa lavage esiswini, bafumana imali eyaneleyo ngeengqalutye carbon iyasebenza okanye ulawulo efakwa ka 0.9% solution sodium chloride.

Intsebenziswano kunye namanye amachiza

Ukusetyenziswa ichiza "Valz", apho analogs kufuneka iindlela ezifanayo samanyathelo, zifuna ngenyameko lo gama emisela amanye amaqela amayeza.

Zingangeni iqela potassium zingawucongi womchamo kunye nezongezo potassium, a ityuwa yayo, kuthetha ukuxhasa ukwanda kwinqanaba le isiqalelo mkhondo kwi plasma yegazi (umz: "lweeHedfowuni") ukuze bandiqumbise hyperkalemia.

Co-ulawulo namanye amachiza umfutho okanye womchamo iphucula isiphumo phantsi "Valz" iziyobisi. analogs zaso kukho intsebenziswano efanayo.

Ukuqeshwa non-steroidal amachiza-ukudumba isenokuba buthathaka umfutho.

Co-ulawulo inhibitors ACE kunye neziyobisi lithium kunokubangela ukunyuka ingathityazwa xi le element mkhondo kwi-plasma, kude kuphuhliso inkqubo ityhefu.

Analogs ze ingxenye main

Phawula, ezinye arhente esebenzayo kuyinxalenye "Valz" ukulungiselela imfundo manual. Analogs phezu kweli njengenqobo yokugweba, ukuba iziphumo ezifanayo emzimbeni - amacwecwe "Valsafors" (Germany), "Valaar", "Valsakor" (eSlovenia), "Valsartan" (Switzerland), "Diovan" (Switzerland), "Tareg" (Switzerland ), "Nortivan" (saseHungary), "Valsartan Zentiva" (Czech Republic), "Tantordio" (India). Injongo nefuthe lamachiza yinkqubo renin-angiotensin.

Drug "Valz": Amacwecwe analogu iqela imithi

Le ndlela kunxulumene blocker of angiotensin II receptors ngokwesiseko apho ichiza ungakhetha indlela efana amanyathelo kunye nefuthe kubonakala. Namhlanje sakhulula inani elikhulu noontanga eli chiza, iinkampani ikakhulu amazwe.

Inani elikhulu zamachiza eyenziweyo ngokusekelwe losartan kweziyobisi, maxa wambi xa zidityaniswe kunye hydrochlorothiazide umchamo. Ezi amalungiselelo 'Cozaar', 'Gizaar "," Lorista "," Lozap dibanisa "," Vazotenz "yaye" Prozartan ".

Le medicament "Valz" - analogu "Diovan" pilisi, "Co-Diovan", "Exforge", "Valsakor" ye isithako valsartan esebenzayo.

Le into esebenzayo yi eprosartan yinxalenye preperatov "Teveten" yaye "Teveten Plus".

Icandelo telmisartan uqulathwe ku amayeza "Mikardis" yaye "Mikardis plus."

irbersartan ingxenye yinxalenye yokulungiselela "Aprovel" njengabaluleke ngamazwe.

Praparat "Valz H": nabalingani Russian

Phakathi amachiza zasekhaya yelo qela amayeza nga bodwa arhente iqinile "Angiakand" eliquka njengoko njengempembelelo candesartan esebenzayo. Iveliswe eli chiza xa inkampani eMoscow "Kanonfarma". Uyakwazi kusithenga ngexabiso ukusuka engange-400 ukuya kuma-700, kuxhomekeke kwisiqulatho icandelo esebenzayo kunye nenani amacwecwe pack nganye.

Enye ummeli yemarike zoxubo Russian yindlela "Bloktran", ngokusekelwe losartan kweziyobisi esebenzayo. Iveliswe yinkampani "Pharmstandard" kwi Kursk. Pharmacy zingathengwa ngaphakathi engange 150-200 pack nganye.

Oku kuthetha (i-analogu of "Valza") kunye namanye onke efanayo kuyo, kuba nemiphumo efanayo kunye kahle eliphezulu evumela ukuba ukuncoma ukusetyenziswa kwazo ekunciphiseni uxinzelelo lwegazi. Ngamana libonakale ixabiso "Bloktran" iziyobisi, kodwa aninako ukhetho lwakho ngokupheleleyo kwixabiso, kuyimfuneko ukuba ukuthatha ingqalelo ukusebenza ichiza, ubukho iziganeko ezibi, kunye nezinye izinto ezininzi, ngoko ke ukhetho kufuneka siphathiswe kuphela ukuba iingcali.

Ngoko ke, lo vasodilators qela amayeza wabonisa ayasebenza entle ukuthoba uxinzelelo lwegazi kwisiqalo neqondo eliphantsi ngokwaneleyo yeziphumo ebezingalindelekanga. Izinto eziluncedo ze yokulungiselela "Valz" kunye analogs zaso ubalisa ukungabikho uyeka, ukukwazi ukufumana iipilisi kanye ngosuku (ekukhethwa ukuba ngexesha elinye), ukungabikho inyathelo ngokukhawuleza lonyuselo.