"Topiramate": imiyalelo ukusetyenziswa, migraine yokwenene, analogs

Ukuphazamiseka kwenkqubo nervous esilimaza ukusebenza yonke eziphilayo. Umzekelo, ukuba nesifo sokuwa enjalo, loo mntu ufumana yokukhubazeka ebomini. Ngokwendalo, nale ngezifo kufuneka silwe rhoqo ukunciphisa izehlo okanye ukuthintela ukubonakaliswa bahlaselwe. Ukulungiselela "topiramate", imiyalelo yokusetyenziswa eziya kusetwa kuphuma apha, nje ukuba unyango le ngezifo. Ukongeza, inokusetyenziswa ukulwa nezinye izifo. Le mveliso ilungiselelwe ukusetyenziswa kwixesha elide.

inkcazo jikelele yokulungiselela kunye nokwakheka

"Topiramate", imiyalelo yokusetyenziswa apho kufanele ukucaciswa ngenyameko isigulane, kuba i-arhente antiepileptic esetyenziswa yoncedo kunye nokuthintelwa ukuxhuzula. Kwiimeko ezininzi ichiza eziveliswa ngokohlobo tablets, ngaphakathi apho kukho ngumgubo emhlophe. Iipilisi e imiqulu blister we-orenji. Kwenye kubo elinokuqukatha 25 okanye 10 mg esisebenza - topiramate. Ngaphezu koko, ngo imveliso ingena dihydrate calcium hydrogen phosphate, nemagnesium stearate, starch, enzima wemagniziyam hydroxycarbonate. Iyeza ukuvimba isenzo pulses eziziisekondari kunye nokuthintela ukuxhuzula.

Emva kokuba isigulane ukuba uthathe iziyobisi, oko ako ngokukhawuleza kakhulu esiswini kunye amathumbu. Kunye neeproteni igazi yinto ephambili esebenzayo ubotshelelwe% 13-17 kuphela. Eli nani liphezulu topiramate egazini waphawula emva kwemizuzu 120. Kukhuthaza kweziyobisi kunye metabolites yayo ziveliswa ikakhulu kwi yokuchama. Half-ubomi ziiyure ezingama-21. Nangona eli thuba angandiswa kwimeko iingxaki wesibindi, nezintso.

Ubungqina obubonakalayo buxela

Ukuba uthe wamiselwa ichiza "Topiramate" yemiyalezo ithi ezi okukhomba:

• Ukuxhuzula Bamqumbisa syndrome Lennox-Gastaut (njenge-arhente nokuxhasa).
• Le wokuqinisa-clonic ukuxhuzula buso okanye ngokubanzi (monotherapy).
• Sokuwa kubantwana abaminyaka 3 abadala (onesethi yokuqala).
• Kuthintelo migraine abadala.
• Zomzimba.
• uxinzelelo Post-traumatic.
• Alcohol Syndrome.
• ifomu njengemanic-depressive.
• kwengqondo.

Iyeza uyakwazi ukubuyisela isimo. Njengoko ubona, "topiramate", imiyalelo zokusetyenziswa apho kusoloko iphakheji le mveliso, enoluhlu encinane izicelo. Noko ke, kule meko ke kuyimfuneko ukuba silumke negumbi lakhe, njengoko le iyeza kucingwa namandla.

Izimo kunye neentsilelo nokusetyenziswa

Nangona ukusebenza esi sixhobo, ayikhuthazwa kwezinye iimeko. Phakathi Izimo bungabonakala ngolu hlobo lulandelayo:

• yobudala yabantwana (iminyaka ukuya ku-2). Ichiza sinamandla kakhulu emzimbeni lomntwana.
• Ukunganyamezelani kuthetha okanye ezinye iindawo kuyo.
• Ngethuba lokukhulelwa zisanyisa. Eyona nto iphambili esebenzayo unako ukungena kuyo yonke imiqobo ngobisi lwebele.
• Utyekelo ukwenza amatye zezintso.
• iinkqubo ezimandundu ukudumba emzimbeni, ezimbi kakhulu ezondeleyo.

Nokwabela "topiramate" migraine kweziyobisi, ugqirha kufuneka ibe ingqalelo ngokukodwa kwabo izigulane abanengxaki umsebenzi wezintso kwaye zesibindi. Launch isithuthi emzimbeni kule meko kuyehla, ngoko iingxaki engalindelekanga zingavela.

Yintoni iziphumo ebezingalindelekanga kungenzeka?

Ukuba uthe wamiselwa iziyobisi "topiramate", umyalelo inika yimbonakalo reactions ezibi:

• Isiyezi, intloko ebuhlungu, iingxaki umbono, nentetho engekho mgaqweni, ukwanda uvalo. Kusenokuba abonakale lengqondo abazizidalwa, ukudinwa, ukungakwazi ukunikela ingqalelo.
• Somnolence, lability ngokweemvakalelo, uxinezeleko.
• Kwiimeko ezinqabe kakhulu, ilahleko memory zexesha elifutshane, ukudideka osezingqondweni, ukuphazamiseka ukungcamla kuyabuya.
• Isicaphucaphu kunye nokugabha.
• isibindi.
• hepatitis Non-esosulelayo.
• umzimba.
• iintlungu esiswini.
• Ukugodola.
• Ngamanye amaxesha oku kunganyusa iqondo lobushushu.
• Ukungabikho esexesheni, epistaxis, ukwehlisa leukocytes igazi.
• Kwiimeko ezinqabe kakhulu, nemibono esinokubakho.
• Ukuncipha acuity ezibonwayo, kwaye yaphula umsebenzi lwemoto ubudala (zihamba ngokuzenzekelayo). Kodwa kusenokubakho kubekho ukudumba conjunctiva.
• Ukudumba iintsini.
• Kome emlonyeni.
• Ukwehla yobuntu emadodeni kunye nabafazi. I zangaphambili nokuba ukuhlasela induku.
• Gastritis kunye isilonda esiswini.
• Lurhudo okanye nokuqunjelwa.
• Ungqinisiso.
• iintlungu kwezihlunu, buthathaka.
• Ingxolo okanye unkenteza ezindlebeni, kwaye maxa wambi kuzwa.
• Ukophulwa yokubhala nokufunda ebantwaneni.
• ndindisholo of yesiqephu.
• Zokunciphisa ukukhula kubantwana, buthathaka ngamandla ithambo.
• ziyabagulisa ziyabonakala kwi eluswini: sokudlathuka kweenwele, irhashalala, izilonda.

Njengoko ubona, ichiza "Topiramate" migraine kufuneka ukuba uthathe ngenyameko. Ngakumbi nzima ngayo abantwana. Ngoko ke, kufuneka bathobele ngokungqongqo idosi. Kulo mzekelo, koogqirha kunye nabazali kufuneka kusoloko esweni imeko wosana.

Iimpawu idosi isicelo

Zikhetheleni eboniswe ichiza inokuba ngugqirha kuphela. Self-ukuqala ulwamkelo yayo akunakwenzeka, njengoko kukho ithuba imandundu. Ukongeza, ichiza buthengiswa ngokumiselwa.

Ukuba sele emiselweyo njengendlela "Topiramate" umyalelo ibonelela ukutya wayo ngomlomo, kungakhathaliseki uhlobo ukukhululwa. Ukusela iyeza kungabelwana kunye nokutya, ingakumbi ekubeni aluchaphazeli inyathelo iipilisi. Kunqweneleka ukuba ukuvelisa ichiza ngexesha elifanayo. Kufuneka ayetyisi okanye ngothanda iipilisi, ekubeni babe incasa ekrakra. Ngaphezu koko, iziyobisi besila nga kulimaza ukusebenza kwayo.

Sebenzisa izinto kufuneka kwenziwe ngolu hlobo lulandelayo:

• Ukuba 'topiramate "macwecwe abayingxenye yohlobo unyango ehlangeneyo anticonvulsant, izinga yonke imihla kweziyobisi ingaba 200-400 mg. Le rate idla yahlulwe amathamo-2. Kubalulekile kakhulu ukuba uqale unyango kunye amathamo ephantsi (25-50 mg), leyo ithathwa iintsuku 7 yonke imihla. Ngaphezu koko, iidosi yaba yintsimi mg-25 okanye 50 kangangeveki okanye ezimbini de inani elilelona, egunyazisa nemiphumo emihle. Thatha amayeza kulo mzekelo, kabini ngemini. ukuze esiphezulu yedosi ukuba izigulane yabadala imihla, 1600 mg.
• Ukuba ugqirha wakho emiselweyo umntwana kweminyaka engama-2 "topiramate", ukusetyenziswa kweli chiza eveliswe yi le nkqubo ilandelayo: qala ukusela iipilisi kufuneka umthamo we-25 mg kabini ngemini. Iyonke imali yokulungiselela ngosuku yi 5-9 mg / ubunzima bomzimba kg. Kungcono kakhulu ukusebenzisa iyeza ngokuhlwa, ngaphambi lokulala, ukucutha umngcipheko yeziphumo ebezingalindelekanga. Ikhondo ephambili unyango ziintsuku ezisi-7. Ukuba kuyimfuneko, esithathwa iiveki enye okanye ezimbini ezanda 1-3 mg / kg. Yokwamkelwa wohlulwe amaxesha 2.
• Ukuba ichiza esetyenziswa monotherapy, ugqirha kufuneka ubonise ingqalelo nomonde. Umele ukulawula nezihlandlo ezibonisa uhlaselwe emva wokususa eminye imithi anticonvulsant. Kufuneka uqale ukuthatha imali ubuncinane 25 mg ngosuku kanye ngemini. Ngaphezu koko, ithamo ukuze kwandiswe, kodwa kwenzeka ngokuthe ngcembe kwiiveki 1-2.
• Ukuba isigulana ungenako ukubathwala unyango olunjalo, ngegalelo lako kungancitshiswa, okanye uwatwabulule lekhefu ukunyusa izinga ukwamkeleka.

Ukuba izinga nokuhlutha siyongezwa, kuyimfuneko ukuba enze ukupheliswa ichiza ngcembe. umthamo ngeveki ye ichiza kuncitshiswa 100 mg.

libanda

Ukuba wabelwe njengendlela "Topiramate" imiyalelo zokusetyenziswa (wena analogs kuxoxwa kamva) apho ukuze uphephe iziphumo ezibangelwa amathamo ngokugqithiseleyo ichiza. Nangona kunjalo, kukho amaxesha xa isigulane ngenxa yesizathu esithile uthatha iipilisi ngaphezu kuyimfuneko. Woba uya kuza libanda.

Lubonakala yi ukuxhuzula landa, ukubonakala nobuthongo, angaboni kahle, ulungelelaniso kunye nokucinga. iziphumo ebezingalindelekanga kunokwenzeka ye libanda, unako mkhulu. Ngokwendalo, kule meko kuyimfuneko ukuba athathe amanyathelo akhawulezileyo siphephe ukufumana isixa esikhulu into kungena kwegazi.

Okokuqala, kufuneka ubize inqwelo yezigulana. Ngaphezu koko, lenquba yenzelwa lavage esiswini. Kwakhona, isigulane kufuneka uthathe iziyobisi izifunxi "Enterosgel" carbon yasebenza. Ukuba indawo unzima kakhulu, isigulane ngokukhawuleza esibhedlele. Kuba ekususeni ichiza ukusuka igazi nkqubo ihaemodialysis kuyasebenza.

Iimpawu yokuxhulumana kunye namanye amachiza

Ukuba ufuna ukuthatha "Topiramate" yemiyalezo (izithethantonye kunokuba neziphumo ezifanayo emzimbeni) uthi ukuba akukho ehambelana nayo yonke imithi. Umzekelo, oku kuyakudityaniswa valproic acid 'pentobarbital "," Carbamazepine ". La machiza zilungiselelwe unyango ukuphazamiseka luvo. ukwamkelwa Joint of ingqalelo aluchaphazeli ingqalelo yabo plasma yegazi. Noko ke, ithamo "topiramate" kungenziwa lincitshiswe. Kuyo nayiphi na imeko, ukuqeshwa kwala machiza ukuba unyango edityanisiwe, esithathwa zonke iindlela mfuneko yokuba amanqaku makalungiswe ngokufanelekileyo.

Ukuba ugqirha wakho egqibile ukumisela iyeza thaca ngokudibene ne "pioglitazone", kubalulekile ukuqwalasela ubume seswekile yesigulana. Ngokuhlanganisa "Topiramate" ne "metformin" kuthi kuphazamisane yokucolwa ekudleni kakhulu emzimbeni. Co-ulawulo wathi iziyobisi with "acetazolamide" kunye analogue yayo kwandisa umngcipheko amatye zezintso.

Kwakhona cinga yokuba ukuze balihlambulule umzimba ichiza kunye metabolites yayo kuthatha iintsuku eziliqela. Xa abantu abane umsebenzi kakuhle kwezintso, eli xesha angandiswa kabini. Kuyimfuneko ukwazi, njengoko kuyimfuneko ukunyenyisa idosi. Izinga le kagqirha amayeza ibala kwimeko nganye.

oyi

Ukuba kufuneka usebenzise i 'Topiramate "iipilisi (imiyalelo ukusetyenziswa yi uxwebhu oluphambili olawula ichiza) kufuneka Ndiyisele ngokungqinelana nemiyalelo gqirha khona. Nangona kunjalo, kukho ezinye imiyalelo ezikhethekileyo ukuba akayi kuhoywa:

• Kwimeko zokurhoxa ayikwazi ukukwenza oko bulula. Into yokuba kukho kungenzeka ukuba kwefrikwensi nobushushu uxhuzula kwanda. Ngoko ke, ukunciphisa imimiselo ye ichiza kufuneka kwenziwe kancinci.
• Enye iziphumo ebezingalindelekanga ichiza ukuze ukudla, nto leyo ekhokelela ukuba womelele zokuncipha umzimba ngenxa umzimba. Ukuze uphephe oku, nceda ubonane nutritionist. Yokudla kufuneka zilungiswe ukuze umzimba ifumana zonke iivithamini eziyimfuneko kunye neeminerali ukuze nokusebenza ngendlela efanelekileyo.
• Ngexesha unyango kufuneka agqitywe iziyobisi psychoactive kunye notywala.
• Medicine "topiramate" (umyalelo, ingxelo, kwaye khona kontanga lulwazi olubaluleke kakhulu kumguli) kunempembelelo enkulu izinga reaction, ngoko ukuqhuba imoto okanye basebenza ngoomatshini ezintsonkothileyo ngexesha unyango kufuneka kube.
• Tablets akufuneki kunikwe abantwana abangaphantsi kweminyaka 2 hletnego.
• Kufuneka silumke gqitha kwabo izigulane kuye kukho kidney ukungathobeli ukusebenza kunye zesibindi.
• Ukuba ungalibali ukuthatha ipilisi ngqongqo ixesha, zama ukuba basele nabo xa ukhumbule. Nakuba kunjalo, ukuba ngaba une kwafika ixesha lokuba wokwamkelwa elandelayo, kuba nenkqubo yokuzilinganisa namazwe aphuhlileyo kufuneka athathe idosi kabini. Kulungile ukuqhubeka ukuba usele amayeza kwisicwangciso echongiweyo.
• ulwazi oluthembekileyo malunga intshukumo mutagenic beziyobisi emzimbeni womntu. Nangona kunjalo, xa befunda iziyobisi kumabuzi Bamqumbisa imbonakalo yamathumba lwesinye. Noko ke, oku kuye kwenzeka ngaphezu umlinganiselo ukuba, yaye kwiimeko ezinqabileyo.

amanyathelo okhuseleko

Ukuba uthathe iziyobisi "Topiramate" yemiyalezo (reviews of iyeza uya kufunda kamva) sicebisa ezinye amanyathelo ukuba umele kudibana ukuze uphephe isenzeko basabele ezibi:

• Ukuba isigulana phezu dialysis, ukulungiselela ukuba amanyathelo esisebenzayo kufuneka kwakhona abeke isiqingatha idosi yemihla ngemihla phambi kokuba inkqubo zokwenza nyulu igazi emva kwayo.
• Ngexesha ukurhoxiswa ichiza kufuneka kwandiswe ukuthathwa fluid. Oku kuya kuthintela isimemezelo ngamatye zezintso.
• Ukuba kukho ubunzima ilahleko kakhulu, kusenokwenzeka ukuba ukunyenyisa idayethi wongeze ngokutya okunesondlo ezikhuthaza ukufunxeka kwezondlo.
• Undesirably kunye "topiramate" kwamkela izinto bandiqumbisayo central system ukudakumba luvo.

Njengoko ubona, eli chiza kunobuzaza kakhulu, ngoko akumele self-medicate, kuba uyakwazi ukwenza izinto zibe mbi nangakumbi.

Features Ukugcinwa, analogs kunye nohlolo

Ukuba zimelwe ngokusebenzisa ezifanelekileyo, ungacela malunga analogs iziyobisi ezifana "topiramate". "Topamax" imiyalelo zokusetyenziswa leyo efana kakhulu nenkcazelo edlulileyo, ngomnye wabo. It has umqobelo efanayo esebenzayo. Kukho nezinye amayeza analogue "Topsaver", "Toreal", "Maksitopir". Ngokuzenzekelayo uvulwe, la machiza akakwazi. Mhlawumbi abayi uya kuyinika nemiphumo emihle, kuba ukwakhiwa kwawo zinokwahluka. Ngaphambi kokuba uqale ukuthatha amayeza ezinikiweyo kufuneka udibane nogqirha. Ingakumbi ngaphandle kagqirha yabo umntu akunakwenzeka uya kubhala.

Gcina iyeza kufuneka ibe kwindawo emnyama apho ukungena ray incinane yokukhanya, ukufuma. Musa ukubeka izinto kude kwimithombo ubushushu. isiqinisekiso sokusebenza yiminyaka-2. Emva kweli xesha, ichiza kufuneka itshatyalaliswe. Kwaye oku kufuneka kwenziwe ukuze kuyo nako ukufikelela abantwana.

Njengoko ngokuba ujongo, zahluke. Izigulane qaphela ukusebenza eliphezulu ichiza kolawulo ukuxhuzula. Ulungile kakhulu uqaqanjelwa. Nangona kunjalo, i-arhente unalo ixabiso eliphezulu. Umzekelo, ixabiso package omnye unokuba engange-600 nangaphezulu. Ukuba ilungile ukusebenzisa ichiza, oko kunceda ukufezekisa kuxolelwe ixesha elide. Nangona kukho ezinye izimvo. Ngokomzekelo, kwezinye iimeko, abantwana baye kakuhle inkumbulo kunye ingqalelo, ulibaziseko yophuhliso, namayeza umntu swi nga pfuna. Kukho kwakhona ukugxagxiseka karhulumente kwizintso.

Kufuneka kuqatshelwe ukuba kwezinye iingingqi lizwe amelwe isiyobisi iyafumaneka kwi ummiselo-free, kuxhomekeka ukungahlawuli ezithile. Kodwa ngaphambi kokuba uthenga isixhobo, kufuneka udibane nogqirha oya ukunika imvume. Khumbula, ukuzihlola izaliswe iingxaki ezinzulu. Siye lwajonga ifuthe kuqulunqo ezifana "topiramate", imiyalelo, ncomo uqaqanjelwa kunye nangaphezulu. Bonisana nogqirha weengxaki zomzimba futhi ube nempilo!