Wolusu Treatment In kwaSirayeli - Oncology Abroad

Unyango lwe advanced (ibakala III kwaye IV), wolusu esikudingayo iindaba ezilungileyo. Nangona izehlo ukunyuka wolusu nge-3 ukuya kwezi-5% ngonyaka ngamnye, umgangatho kunyango wolusu akukho kakhulu kulibala ukuziphilisa izigulane ezininzi. Ulingo lwezonyango ayisosenzo ithemba ilungileyo lokuphelisa nya wolusu kuwenza: indibanisela olutsha lwamachiza, iindlela ezintsha ukulawula kubo. Eyona uthembisa ukuba kunyango lulandelayo imelanoma aphesheya:

• Allovectin-7 - yinto unyango gene into lesitofu ngqo kwi ithumba yomguli kukuba wolusu III okanye iqonga IV, esebenzisa amajoni omzimba ukuba ahlasele thumba. Allovectin izilingo Ekuqaleni zibonise ukuba yamathumba ngo-4% ukuya ku-9% yezigulane basabela kunyango.
• Genasense inhibitor unique bcl-2, iproteni eyenziwe ziiseli zomhlaza. Ngokunciphisa ubungakanani bcl-2 iiseli umhlaza, Genasense kwandisa ukusebenza unyango wolusu. Uhlolisiso lubonisa ukuba Genasense nodibaniso ichemotherapy yandiswe ngokubonakalayo ukusinda zizonke xa kuthelekiswa ne ichemotherapy.
• MVax wolusu lokugonya ilungisiwe ukususela iiseli yomhlaza yakhe umhlaza yesigulane. Amaphononongo amaninzi aye abonisa ukuba MVax kunokukhokelela ukuze kuxolelwe epheleleyo-13% yezigulane, nto leyo ngaphezu kabini kunoko anikwe ngokusebenzisa IL-2 kuphela. MVax nayo ngempumelelo izigulane abanenqanaba III wolusu emva kotyando kokuba kabini kunyaka-5 ukusinda xa kuthelekiswa utyando yedwa.
• Ipilimumab i izoba olwenza amajoni omzimba ukulwa wolusu ziyibuyisela CTLA-4 molecule. Isigaba II iimvavanyo ezintathu ezidlulileyo onyango lubonise ukuba kakuhle unyango imelanoma kwaSirayeli Ipilimumab - ukwandisa ukuphila ukusuka 47% ukuya 51% abo abanenqanaba III okanye IV wolusu, eseyiphantse amaxesha amabini ngaphezulu kwe-avareji inqanaba.
• OncoVEXGM-CSF ugonyo, okusebenzayo ngokusasaza nethumba yaye ebangela ukufa kweeseli umhlaza, zivuse kwamajoni omzimba kwaye batshabalalise nangezilonda kuwenza. Iziphumo izigulane 50 abanenqanaba unresectable IIIc / IV wolusu wabonisa ukuba-28% yezigulane baphendula, kuquka 12% kuko kuxolelwa ngokupheleleyo.

Abo bathathe inxaxheba kwiimvavanyo zeklinikhi, bafumane unyango yakutshanje, adla ukusilela kwamanye amazwe. unyango wolusu akwaSirayeli kuba bhetele ngakumbi umgangatho ukhathalelo kunye nethemba kuphela ezinesifo phambili. Ngamafutshane, ukuthatha inxaxheba kwizifundo lwezonyango ngayo izigulane yeyona ndlela kuphela nathembisayo unyango, unyango ezintsha wolusu aphesheya.