Postinfarction cardiosclerosis. Indlela yokunyanga?

I-postinfarction ye-cardiosclerosis yinkqubo ye-pathological, esekelwe kwimonakalo ye-cardiomyocytes kunye nokutshintshwa kwayo ngamathambo asebenzayo kwisiphumo se- myocardial infarction.

Kwiimeko ezininzi, le ntsholongwane ikhula emva kwe-infyoction ye-myocardial yangaphambili. Ukugqithiswa kokusebenza ngokuqhelekileyo kwemisipha yentliziyo, ukuhanjiswa kwegazi ngokungavumelekanga, kwaye ngoko i-oksijini, entliziyweni yenza ukuba kuphuhliswe i-myocardial infarction. Indlala yokuhlala i-oxygen ye-cardiomyocytes isoloko ibangelwa inkqubo ye-atherosclerotic yeenqwelo ze-coronary.

I-myocardial infarction yi-necrosis (necrosis) yeziza zendawo ezahlukileyo zendawo yentliziyo. Ingqibelelo yayo ibuyiselwa ngokukhula kwiindawo eziwonakalisiweyo zenyama. Nangona kunjalo, ezi zicubu azikwazi ukwenza isivumelwano, nto leyo ekhokelela ekuphulaphulweni komsebenzi wenhliziyo: kukho ukuncitshiswa kweqhekeza le-ejection, ukuphulwa komzimba we-heart and rhyth, kunye nezandi zentliziyo zibe zizithulu.

I-postinfarction ye-cardiosclerosis ibonakaliswe ngumonakalo ogqithiseleyo kwisisu senhliziyo - enye indawo okanye ngaphezulu indawo eneemida ezicacileyo ithatyathwa yimizimba enxulumene nayo.

Kwizonyango, le ntsholongwane ibonakaliswe ngamagumbi adibeneyo (awandisiweyo) entliziyweni, i-hypertrophy (i-thickening) yentliziyo yesisu. Ukuba kukho i-cardiosclerosis, iimpawu zakhe zibonakaliswe ngolu hlobo lulandelayo: ukungakwazi ukwenza umzimba, kunye nokhathala okwedlula, i-tachycardia, i-dyspnea, intlungu entliziyweni, i-edema (ngokokuqala ngqa i-edema ibonakala kwimigangatho ephantsi). Uphawu oluqhelekileyo lubuye lube nexinzelelo, oluphezulu kakhulu kunokoqhelekileyo. I-postinfarction cardiosclerosis ngamanye amaxesha ifunyanwe ngenxa yokubonakala kwe-heart failure failure. Inkxalabo yexesha eliqhelekileyo yesi sifo kukungagqibekanga kweempahla, okunciphisa ukuhanjiswa kwe-oksijini kwizitho, kwakunye neentliziyo zomzimba ngokwazo.

Unyango lwe-cardiosclerosis kufuneka uqale ngokukhawuleza, ngokukhawuleza. Kwinqanaba langoku, iindlela ezahlukeneyo zisetyenzisiweyo. Ukukhuthaza umsebenzi wentliziyo, isingeniso sokunciphisa kwayo, umphumo kwisifo se-cardiomyocytes, unyango lwamayeza lwenziwa. Amachiza ukwandisa isivumelwano sokubambisana kweengxenye ze-myocardium.

Ukunciphisa ubunzima bomzimba obuninzi kunceda ukunciphisa umthwalo entliziyweni. Ukuba ubunzima obuninzi bubangelwa yi-edematous fluid, ngoko ke kuyimfuneko ukuthatha i-diuretics, eya kukunciphisa ukuvuvukala, kwaye, ngokufanelekileyo, isisindo somzimba.

I-postinfarction i-cardiosclerosis kakhulu ayidingi ukungenelela ngonyango: kuphela ngokuphulwa okukhulu kwintliziyo yomculo okanye umonakalo kwiinqanawa ze-coronary. Ezi zigulane ziya kufakwa kwi-stent ukulungiselela ukukhulisa i-lumen yeempahla. I-Aortocoronary shunting inokwenzeka.

I-carbodidium kunye neempahla ziyakwazi ukuhlaziywa ngokutsha kunye ne-operation.

Ngokuchanekileyo kwaye ekugqibeleni ukulahla i-postinfarction cardiosclerosis kuya kunceda ukutshaya amaseli. Amaseli esitembu akhuthaza ukuhlaziywa kwezicubu kunye nentliziyo, neempahla kunye nezinye izitho kunye nezicubu. Ukutshintshwa kwezi zisele kuqhutyelwa kwisigulana sonyango kwizibhedlele zekliniki. Ngokuhamba kwegazi, bafikelela kwi-myocardium, apho badibana khona kwiindawo eziphilileyo. Emva koko ama-cell stem axhasa i-fibroblasts eyenza izikrakra, aze ahluke kwi-cardiomyoblasts. Ngaloo ndlela, ukuvuselelwa kwe-myocardial kwenzeka kwiinyanga ezili-9-12. Iimpawu ezintle zonyango lwe-postinfarction cardiosclerosis ziphawulwe zizigulane kunye nezifundo eziqinisekisiweyo zonyango.