Phosphatase awana: iqhelekile kwabasetyhini, amadoda kunye nabantwana. phosphatase awana egazini: nanjengokwesimo kwaye ukuphambuka

phosphatase awana i-enzayimi ngqo, lalo kwiqela hydrolases. Le enzyme ibonakala onke amalungu omzimba womntu.

Ingakumbi kuthunyelwa transcriptase ebonakalayo osteoblasts, isisu isifo iqokobhe, kwi nobubovu mammary, ngumkhaya, bile duct ezindongeni.

Types of phosphatase obrak

Phosphatase wohlulwe iintlobo:
- placental;
- sezintso;
- isibindi;
- E .;
- bone.

phosphatase awana, kwakunye nazo zonke enzayim ezifanayo kuyo, kufuneka ukuba bapase ezahlukahlukeneyo abasabela kwemichiza phakathi komzimba womntu. Kufuneka imali ubuncinane phosphatase alkali ze enze ezi khemikhali. Ukuba umzimba nakuphi na ukunyhashwa, oko kungathetha ukuba phosphatase obrak landa. Izizathu bendyebo le enzyme inokuba nomahluko kakhulu.

njani awana phosphatase

Le enzyme uwugcinayo defosfolirovaniya reaction. Le yokusabela iqulathe kwi cleavage lwe phosphate ezintweni eziphilayo egcinwe kwinqanaba eziphilayo. phosphatase awana egazini uba rhoqo yoxinaniso ethile. I-enzyme enako ukugqithisa phosphorus ngokusebenzisa iseli ndizayo. Ukongeza, phosphatase - umlinganiselo kwemimiselo icalcium-phosphorus ukutya. Umsebenzi omkhulu enzyme siboniswa pH medium uluhlu 8,6-10,1. Ngenxa yoko igama - awana.

phosphatase awana egazini

Uluhlu ezibonisa amanqanaba eliqhelekileyo igazi phosphatase obrak kakuhle ngokubanzi. Ukufunda ziyahluka ukusuka 44 IU / L ukuya 147 IU / L. Ngaba nangoko aphakuzele ukuba ialakalin phosphatase landa. Kusenokwenzeka ukuba akanangozi ngokupheleleyo. Umzekelo, umlinganiselo phakathi abasetyhini abakhulelweyo ngokuqhelekileyo zabaxwa kancinci. Kwakhona babebiza imali kunye abafikisayo, wawavulayo ibakala ukufikisa. Konke oku kungenxa ekukhuleni ngumkhaya kunye ithambo, yaye ayibonisi ezahlukahlukeneyo ezingaqhelekanga emzimbeni womntu. Kwakhona afune phosphatase ixhomekeke yobudala kunye nesini ngamnye.
Okwangoku akukho ndlela standardised, ngoko ke ukwahluka yemida kwiSithethe ixhomekeke wezenzi ukuba asetyenziswa yilebhu uphando.

phosphatase awana. yinto yamihla le

Enye indlela yokuqingqa ezingaqhelekanga emzimbeni yi phosphatase obrak. Ummiselo amabhinqa, amadoda kunye nabantwana is a bit eyahlukileyo, kufanele kuphawulwe. Inqanaba le enzyme emzimbeni kwabasetyhini ungaphantsana ngaphezu umlinganiselo abantu. Ngoxa abantwana olubonisa inqanaba le enzyme mkhulu kakhulu kubantu abadala.

Izinga eqhelekileyo phosphatase obrak kwi -gazi lwe umntwana:

- kwiintsana: 245-255 IU / L;
- kubantwana abaminyaka 1 ukuya kwiminyaka 9: 345-355 U / L;
- kubantwana abaminyaka-10 ukuya kwi-15: 275-285 U / L;
- intsha, iminyaka engama-16 ukuya ku-19: 145-155 U / L.

Ummiselo amadoda:

kweminyaka eyi 21 ukuya 30 -: 100-110 U / L;
- abaphakathi kweminyaka eli-30 ukuya 45: 110-120 U / L;
- abaphakathi kweminyaka eli-46 ukuya kuma-54: 120-130 U / L;
- abaphakathi kweminyaka eli-55 ukuya ku-70: 135-145 U / L;
- abangaphezu kweminyaka yobudala engama-71: 180-190 U / L.

Xa abadala, ngokuxhomekeka phantsi, kancinane eyahlukileyo obrak phosphatase.

Ummiselo ngayo amabhinqa:

kweminyaka eyi 21 ukuya 30 -: 80-90 U / L;
- abaphakathi kweminyaka eli-30 ukuya 45: 90-100 U / L;
- abaphakathi kweminyaka eli-46 ukuya kuma-54: 105-115 U / L;
- abaphakathi kweminyaka eli-55 ukuya ku-70: 125-135 U / L;
- ubudala '71: 155 -165ed / l;

Oku kunokwenziwa isigqibo sokuba abantu ngokumalunga namanani yabasetyhini, kancinane ephakamileyo obrak phosphatase. Ummiselo ngayo amabhinqa ngaphantsi kwe izinga amadoda ngayo malunga 20 U / L.

Izizathu kwenyuka of phosphatase obrak

Kukho intetho ethi, apho kuxhomekeke le phosphatase obrak. UNorma siyandiswa, kwaye oku kube yingozi kwimpilo. Kodwa kwenzeka and vice versa, xa nongeniselo index na isilumkiso lokuqala nezichanekileyo ukuba umzimba isigulana zikhona komgomo ezibalulekileyo.

Kwi ukwanda ingxelo enzyme zingachaphazela:

Ngomhla inxalenye iphecana biliary wesibindi:

- ithumba we bile duct wenziwamkhulu;
- senyongo, nto leyo ingenza kuvaleke ye bile duct;
- umhlaza wesibindi;
- loloyiko we bile duct, wamqumbisa ngeenkqubo zotyando;
- yamatye bile duct;
- umhlaza esiswini okanye pancreas;
- ukuqina;
- mononucleosis Infectious;
- nayiphi na hepatitis imvelaphi. Kule sifo malunga-3-Songa ukwanda phosphatase obrak.

Izizathu phezu inxalenye ithambo achaphazelekayo:

- isifo Paget kaThixo. Esi sifo sizibonakalisa kukukhula engaqhelekanga ithambo, kwakunye ukuphazamiseka kwiindawo ezithile amathambo. Kule sifo, kukho amanqanaba aphezulu kakhulu enzyme ethathelwa ingqalelo;
- ithumba amathambo;
- osteosarcoma, nto leyo ithumba kwi ithambo;
- osteomalacia nomsindo calcium ngxaki (osteomalacia).

Ezinye izizathu:

- iposi engabalulekanga;
- hyperparathyroidism, esi sifo hormone, xa ebona agqithisile hormone parathyroid, parathyroid kwakhiwa. Ngenxa koko ukuhluzeka kuloko icalcium ukusuka amathambo;
- perforation isisu (nge-umonakalo);
- okwenziwa sisilonda sikabhobhosi.

Izizathu amaqondo aphantsi phosphatase obrak

Oku akusoloko kuthathwa unxaxho into eziphakamileyo obrak phosphatase. Ummiselo kwabasetyhini kunye namadoda basenokubanika diverge phantsi.

A amanqanaba ukuwa phosphatase kungachaphazela:

- ukutofelwa igazi ngeedosi amakhulu;
- anaemia obunzima;
- hypothyroidism (function lengqula eliphantsi);
- gipofostataziya (yesifo azalwa ezinqabileyo leyo ebangela ukuba ukuthamba emathanjeni);
- izixa elingonelanga nezinki emzimbeni;
- ukusilela ngumkhaya (kwabasetyhini abakhulelweyo).

Yintoni kuchaphazela isiphumo

Ukwandisa:

- Ngexesha lokukhulelwa, ngumkhaya iqulethe phosphatase obrak. Ummiselo for abafazi kweli xesha akujongwa ukuba kakhulu;
- emva Ukophuka uthi i Linyuke kakhulu phosphatase obrak;
- ekubeni abantwana abafikisayo bekusoloko ukukhula ngokukhawuleza amathambo, umyinge wokuphelelwa enzyme landisa inqanaba ingxoxo;
- ukunyusa umgangatho phosphatase egazini kunokuba, yaye ezinye iziyobisi, ezifana "paracetamol", "aspirin", "Allopurinol", antibiotics ezahlukeneyo, kunye neentlobo ngeentlobo kwamanye amachiza;
- enzyme data defosfolirovaniya iindima inokubonakalisa, emva okupholisa, esithatyathwe uvavanyo lwegazi.

Ngomhla ukwehlisa izinga le enzyme zingachaphazela zokucwangcisa ngomlomo.

Uhlalutyo for phosphatase obrak

Ngelo xesha ukuthatha uhlalutyo phosphatase obrak egazini ukuya serum umnikelo masidibanise wezenzi ezithile ukuba basabela njani phosphatase. Emva koko, usebenzisa ubuchule ngqo, uyazikhomba imveliso ifunyenwe ulinganiswa. Xa lolwabo nganye, nokuba emathunjini, isibindi okanye ngumkhaya, siqulethe uhlobo oluthile phosphatase obrak. Ngexesha uhlalutyo xi elilinganisiweyo enzyme ethile.

Ukuze kunikezela phezu uhlalutyo igazi lakhe ukuze enzyme, isigulana siya kufuneka imizuzu embalwa. Kwezinye iimeko, abantu amathumbu emva kokutya kakhulu wavelisa obrak phosphatase. Kulo mzekelo, iziphumo lokuvandlakanya igqwethekile. Ngoko ke, lo sigulane asikwazi ukuthatha ukutya okanye usele amanzi phambi kokuba unikezelo yokuhlaziya.

Ngenxa iindlela kwilebhu mihla, iziphumo zovavanyo ziya kuba zilungele emva kweeyure ezimbalwa.

Ngokusekelwe yonke idatha, sinokugqiba ukuba phosphatase ubuncinane obrak egazini - eqhelekileyo. Ukwandisa izinga le enzyme isenokuthi isilumkiso naluphi na utyeshelo okanye ukunyhashwa, kwaye ngokupheleleyo nalinye ityala inkxalabo. Nakowuphi na umzekelo, oku isalathisi lokugqibela utshintsho emzimbeni womntu.