Isiza 'Retinol acetate'. Imiyalelo

Isiza "I-retinol acetate" imfundiso ibhekisela kwiqela le-pharmacotherapeutic lamavithamini. I-remedy inceda ukuzalisa ukungabikho kwe vithamini A.

Iipilisi kunye ne-"Retinol acetate" isisombululo sikhuthaza ukusetyenziswa kweenkqubo ze-redox, ukuthatha inxaxheba kwimimiselo ye-metabolism, ukudala iimeko ezifanelekileyo zokuhlanganiswa kwe-ATP. Isilwanyana sishukumisa inkqubo ye-epithelization, inqanda i-hyperkeratosis (i-cornification excess of epithelium). Ukongezelela, i-agent igxininisa umsebenzi wokukhupha kunye neengqungquthela zokuzilahla.

Xa ulawulwa ngomlomo, le nkunkuma isondele ngokupheleleyo kwi-system digestive. Imveliso ye-Metabolism (i-retinoic acid, retinal, retinol kunye ne-retinyl palmitate) isasazwa ngamalungu kunye nezicubu ezingafaniyo. Uxinaniso oluphezulu lubonakala kwi-retina kunye nesibindi. Isixa esincinci sitholakala kwiingqungquthela ze-adrenal, isifuba (i-lactating), imiphunga, iintengiso zeenqatha, intliziyo, iintso.

Isixhobo "I-retinol acetate" imyalelo isincoma ukuba i-vitamin defence kunye ne-hypovitaminosis A, izifo ezithathelwanayo (i-pneumonia, i-bronchitis, i-tracheitis, i-dysentery, imasese). Isilwanyana siboniswe kwizifo zesikhumba (ezinye iifom ze-eczema, pyoderma, i-psoriasis, ichthyosis, i-hyperkeratosis, isifo sesifo sofuba, amanxeba, amaqabunga, ukutshisa, iinkqubo eziphazamisayo nezivuzayo). Isixhobo "I-Retinol acetate" imyalelo icebisa izifo ze-ophthalmic (conjunctivitis, izilonda ze-eczematous ze-eyelids, keratomalacia, xerophthalmia, hemostalopia, retinitis ye-pigment). Izibonakaliso ziquka izifo zokuphefumula ezinzulu, ukungondleki, izilwanyana, iintsholongwane ezingapheliyo, i-leukemia, izibilini ze-epithelial, i-cirrhosis, ingqondo.

Ukulungiswa kwe-"Retinol acetate" kucetyiswa ukuba kusetyenziswe phantsi kolawulo logqirha. I-remedy kufuneka ithathwe emva kokutya ngokuhlwa ebusuku okanye kusasa.

Nge-avitaminosis yamadridi aphakathi kunye nobumnene, imilinganiselo yokwelapha imiselwe ngolu hlobo lulandelayo: abadala - ngemini ukuya kwi-33 000 IU, ye-pigment retinitis, i-xerophthalmia, i-hemeralopia - 50 000-100 000 IU. Isisiseko sabantwana sisetyenziswe ngokweminyaka ukusuka ku-1000 ukuya ku-5000 IU ngosuku.

Xa i-pathologies yabantu abadala becetyiswa ukuba babe ngama-50 -100 amawaka i-IU, abantwana-ukusuka kwi-5 ukuya kwi-20 lamawaka i-IU ngosuku.

Isilinganiselo somthamo omnye akufanele sidlule kumawaka ama-50 IU (kubantu abadala) kunye namawaka ama-5 IU (kubantwana). Ngosuku aluvumelekanga ukuthatha amawaka angama-100 ama-IU kubantu abadala kunye namawaka angama-20 IU kubantwana.

Xa usebenzisa i-drug "i-retinol acetate" kuma-dosage aphakamileyo, kukho i-tatogenic effect, eqhubekayo emva kokuhoxiswa kwayo. Kule nxu lumano, kunokwenzeka ukucwangcisa ukukhulelwa kuphela ezintandathu ukuya kweenyanga ezilishumi elinesibini emva kokuphela kwenkqubo yokwelapha.

Ngokusetyenziswa kweziyobisi "I-retinol acetate" nemiphumo emibi ingenzeka. Ukulala, ukuphelelwa ngumkhuhlane, ukuhlanza, ukunyaniseka, isisongela, intloko ingenzeka. Kwezinye iimeko, kukho ukuphulwa komthwalo, umlenze wesigxina, ukukhwabanisa isikhumba. Xa uthatha amanani aphakamileyo, i-hypervitaminosis inokwenzeka. Isilwanyana "I-Retinol acetate" ebantwaneni kunokubangela ukwanda kwenycinezelo yomshuwalense ( cerebrospinal pressure) (kwiintsana zinokumakishwa ukutshatyalaliswa kwefontiel kunye ne-hydrocephalus), inqabana elukhumbeni, ukuhlanza, ukukhupha, mhlawumbi ukunyuka kwamaqondo obushushu. Kwiimeko ezinqabileyo, ngomhla wokuqala wonyango, i-rashes-papular rashes ephasayo ingenzeka. Oku kufuna ukukhanselwa kweemali.

Ngenxa yokunciphisa umlinganiselo okanye ukuhoxiswa kwexeshana kwilisi ye-retinol acetate, iziphumo ezibi zihlala ziphela.

Isicatshulwa siyaphikisana nokukhulelwa (kwi-trimester yokuqala yesisu), kunye ne-cholelithiasis, i-hypersensitivity, i-pancreatitis engapheliyo.

Iyeza "Retinol acetate" (ukuphononongwa kwabanye abantu kubonisa oku) kunokusetyenziswa kwiyeza zonyango. Ngaloo ndlela, isilwanyana siyasebenza kwi-hyperkeratosis kwizilwanyana.

Musa ukuthatha isilwanyana "Retinol acetate" ngaphandle kokubonisana nengcali. Ngaphambi kokusetyenziswa, kufuneka ufunde isichaso.