Isifo Horton esithi: oonobangela, iimpawu, isifo kwaye afumane unyango

Enye kakhulu rhoqo kwaye yingozi kwimpilo kwezifo ezinemigca izifo Horton kaThixo. Kunokuba kuyingozi nendlela ukuphathwa, kuya kuxoxwa apha.

Uhlobo sifo

isifo Horton kukaThixo nayo eyaziwa phantsi amagama afana cell giant arteritis zexeshana okanye vasculitis. Esi sifo fanele ukuba udidi samathambo nabalinganiswa arhabaxa unxiba. Njengezinye vasculitis systemic, sukube ichaphazela imithambo yegazi, kunye nezinye imithambo yegazi enkulu. rhoqo lo sifo yenzelwe ngaphakathi esingxotyeni carotid.

Esi sifo ithiywe emva kogqirha Horton kaThixo. Isifo yabhaqwa Melika kwi banesifo zenkulungwane yamashumi amabini. Iinkcukacha-manani zibonisa ukuba arteritis zexeshana ixhaphake kakhulu kumantla Yurophu kunye namazwe yeYurophu. Njengoko umthetho, esi sifo sichaphazela abantu yobudala yomhlala-phantsi, kunye nabafazi ubunzima phantse kabini kangangoko abantu.

ngumba

Kukholelwa ukuba isifo Horton lenzeka ngenxa nethontsi kwinqanaba nezifo zabantu. iimvavanyo ezininzi kwegazi zibonisa ukuba indawo vasculitis sisilonda esidumbileyoesingaphakathi kwemithambo kuzakha izilwa-buhlungu. Ngaphezu koko, uphuhliso esi sifo kuxhomekeka kubukho kumzimba iintsholongwane uqhuzu ezifana herpes, hepatitis, arhente ifiva. Ngaphezu kwazo zonke ezi zinto zingasentla, kukho kwakhona izazinzulu kunye ingcamango yofuzo kunokwenzeka, njengoko ibonisa ubukho kumatyala sofuzo efanayo.

isifo Horton kaThixo, iimpawu zazo zahlukahlukene kakhulu kwindalo, unako ukubonisa iimpawu zabo ukusuka kwiiveki eziliqela iinyanga eziliqela. Ngamanye amaxesha uphuhliso sifo kwandiswa emva igciwane lohlobo okanye ebandayo isifo. Iimpawu zesi sifo lungohlulwa lube jikelele, iimpawu izilonda nemithambo kunye ukuhla embonweni. Njengoko umthetho, ubukho ubuncinane omnye kubo ukufumana ukuba yeyiphi ugqirha kbafownlwa.

iimpawu Common

Kubonakaliswa isifo Horton yeyona ifiva, rhoqo kwaye yababuhlungu yintloko, ngokukhawuleza ukwehla kobunzima, ukudinwa, izifo zokulala, iintlungu amalungu kunye nezihlunu. Yona ke intlungu entloko, oko kunokuthi kwenzeke kwenye inxalenye lukakayi, yaye ezininzi kwaoko yaye, njengoko umthetho, inophawu eliguquguqukayo. Amaninzi, iintlungu kwenzeka ebusuku, yaye ekugqibeleni obukhulu ngakumbi kuphela. Ukongeza kwizigulane migraine ukuze sibe nenkxalabo malunga antsi entlonzeni, iintlungu xa ethetha okanye ukutya, mizwa ekhathazayo kwindawo yobuso. Ubuhlungu imisipha namalungu abekiwe, ngokuqhelekileyo kwindawo emagxeni okanye ethangeni. Uhlobo ubuhlungu na uhlobo efanayo samathambo.

isifo semithambo

Nezitsha, isifo Horton kaThixo baye ukugangatheka. Ludla thatha uhlobo maqhuqhuva, ebuhlungu eshushu ukuya ngaphandle kwebala. Ngaloo kwiinqanawa ezinjalo akukho zimpawu izinga lentliziyo kunye nentshukumo negazi. On entlonzeni kangangoko ubukho zamanzi ukudumba. Ngaphezu koko, kakhulu rhoqo ezikufuphi imithambo ulusu ukutshintsha umbala ukuba yingqombela lwaseBurgundy. Mhlawumbi imbonakalo nokudumba kwi Horton syndrome.

Esi sifo, ophuma kummandla lwangaphakathi kwimithambo carotid, iyingozi kakhulu. Oku kungenxa yokuba ngokuchonga iimpawu lwangaphandle kunzima. Iingxaki kule khosi sifo ngenxa yokuba umonakalo kakhulu iinqanawa ezinkulu hayi ziyazibhaqekela ngexesha, kungakhokelela ekubeni nemiphumela emibi ezimbi, ezifana kobetho legazi.

Fall umbono

Kwenye ingxenye nzima kakhulu kuphuhliso lwesifo Horton kaThixo iliso. Kubonakaliswa isifo semithambo kaninzi kakhulu enxulunyaniswa ukwanda koxinzelelo, iintlungu, uphuphu kunye nezinye ukungaqheleki embonweni. Oku kubangelwa ikakhulu ukuya yokungabikho kwegazi efanelekileyo kwegazi kule ndawo. Xa inokuphetshwa ixesha unyango kuqala lweziqhamo kakhulu, kungenjalo isigulane esongela ukugqiba yoma le-luvo optic nokungaboni elandelayo.

ekuxilongweni

Esi sifo kukhethwa ukubonwa uhlolo olubonakalayo Iziphumo zohlalutyo zonyango nophando. Xa ukuhlola imeko isigulana ukunikela ingqalelo kakhulu kwimpilo-luvo. Kubangel 'umdla ukwazi ukuba esi sifo kuchaphazela kakubi umgangatho mbono, ngoko ke khangela idlala indima ebalulekileyo. Njengoko izifundo laboratory biopsy esithathwe isitya eyonakeleyo, kwakunye isigulane eyabelwe Doppler ultrasound, livakale Imagnethi okanye Itomography ayifum zobuchopho.

Iziphumo zophando

I afunyenwe ngexesha data Uxilongo kugweba ibakala sifo kwaye isigqibo unyango. Ngokuqhelekileyo, iziphumo ezihlangeneyo ulwazi olufunyenwe emva kokuba sicatshulwa zophando zoviwo kunye elabhoratri.

Ngenxa yoko lobukho yokuqokelela igazi kumisa iiseli igazi insufficiency ukuphucula leukocyte kunye erythrocyte neentlenge lunikezelo. Xa ucazululo olupheleleyo Kwangale ngokuqhelekileyo bekubona utshintsho ratio ye amaqhezu nezo kwinqanaba igazi ukuhla albumin kunye.

Xa isifundo oogqirha anikele ingqalelo ekhethekileyo ukusekwa namandla aso kunye nobukho iziphene kwaye umonakalo emazantsi yangaphakathi esweni.

izifundo Biopsy zezixhobo yeselula kunye isitya yonakele wavunyelwa ukuba utshintsho nabungozi Ebubanzini kunye nolwakhiwo umkhumbi Horton syndrome. Esi sifo sidla kwenzeka ngendlela evelayo sisezindongeni maqhuqhuva imithambo granulovidnyh. Loo uphuhliso akakwazi kuchaphazela ukusebenza benqanawa: ekuhambeni kwexesha, le mithambo uba ayemxinwa kwaye kwezi mpawu zingasentla.

Nangona kunjalo, kukho iimeko xa utshintsho ezo kwemithambo okanye vein akukho ulandelwe. Oku kuchazwe into yokuba ukulahleka isikepe ekwisimo ekujoliswe kakhulu kwaye ayisoloko efanele ukusekwa. Oku kubangelwa yinto yokuba sisilonda esidumbileyoesingaphakathi na ukuba umthambo segmental ngokwendalo kwaye ngethuba ukuthatha biopsy ukuze inxalenye alichaphazeleki kwemithambo.

Ukongeza, zonke iimpawu zixhomekeke kuphela iimpawu umzimba isigulane ngasinye ngamnye, ukuquka ubudala, yokuphila kunye nezinye izinto. Umzekelo, i-Association of rheumatologists American inika amanani abonisa ukuba le khosi yesi sifo iphenjelelwa ngamandla kakhulu ezahlukeneyo izinto demographic. Ziquka yobudala yesigulane, ingakumbi ukuba uneminyaka engaphezu kwama-50.

Ingxaki ekuxilongweni

Xa umisela iimpawu zesifo Horton kufuneka kananjalo kwahlule kuyo izifo ezifanayo, ezifana samathambo, rheumatism, neuralgia, ezimbi yenkqubo emithanjeni, vasculitis lwenkqubo. Oku kuyinyani ingakumbi kubantu abadala. Flow zingohluka ukuba amanye amaqela ubudala, ekubeni kudla kakhulu itshintsha emithanjeni yegazi, ezinxulumene kunye nezinye iSifo, bamba inkcazelo Horton syndrome. Isifo edidekile, umzekelo, yegazi. Noko ke, kule meko uqaqanjelwa intloko yakhe umlinganiswa eyahlukileyo kakhulu. Ngaphezu koko, vasculitis iyahluka inqanaba okukhulu ngakumbi neentlenge kunye notshintsho luphuhle e emithanjeni, nto leyo ziboniswa kwi biopsy. Ngamanye amaxesha iimpawu axubeneyo kunokubangela ingxaki kwi isigulana eso, ukuba ugqirha kbafownlwa.

unyango

Ukubatshabalalisa sifo lwenziwa ngokusetyenziswa glucocorticoids. Ngokuqhelekileyo, ekuqaleni konyango, ugqirha iimpawu unyango kwala machiza, leyo ngaphezu kweminyaka emibini. Le khosi inqanyulelwe, ukuba isigulane ivela inkululeko epheleleyo kwizifo kunye likakade. Ukusetyenziswa corticosteroids kunempembelelo entle isifo Horton.

Unyango nge arhente hormone lwenziwa kwi sekethe ahambelanayo ithathela ingqalelo bokuqonda esi sifo. Xa kuphuhliso olucothayo kakhulu isigulana lalathelwe ngokwenza amacwecwe eziqulathe prednisone nganye ukususela milligrams-20 ukuya kuma-80 ngosuku. Kunye nophuhliso ngamandla esi sifo kunilungele ngakumbi ukusebenzisa unyango kukothuka kunye amathamo eliphezulu methylprednisolone. Emva kwenyanga yonyango amaninzi kungacutha idosi. Kulo mzekelo, zonke idosi veki lancipha ukugcina ngokwenqanaba malunga 5-7.5 milligrams ngosuku. Emva kweminyaka emibini unyango isenokuba ukupheliswa unyango engekho likakade. Ezidlulileyo kweenyanga ezintandathu, isigulana sibe phezu idosi nokugcinwa 2-2.5 milligrams beziyobisi hormone yonke imihla.

Nangona kunjalo, le meko kunokwenzeka xa unyango kunye glucocorticoids ayiniki yifuna. Kulo mzekelo, uyacebiswa ukuba ukunyanga ukuqeshwa cytostatics. Ngaphezu koko, ukongeza kuthomalaliso kwamadlala nga akhutshwe amachiza obhobhozayo anticoagulant kunye antihistamines.

abantu abane kwesifo

Kufuneka kuqatshelwe kanjalo ukuba esi sifo kusisisongelo kubomi nomonde, njengoko umthetho, hayi zimelwe. Amanye amatyala ezinqabileyo imisinga ukugula aphilileyo kunokwenza ukuba umbono, kuquka ubumfama, ngokunjalo kuphuhliso kokubetha, isifo sentliziyo kunye necrosis. Nangona kunjalo, esi sifo enyangekayo kwiimeko ezininzi. I-ALS ukulapha ukhethe kakuhle kakhulu intle. Xa engekho ukuphinda kwiminyaka emibini elandelayo, ubomi isigulane esithi, mhlawumbi, baya kuba nendawo kwixesha elizayo yobomi bakhe. iingxaki Rare ngexesha unyango esinxulunyaniswa kuphela nezigulane zabucala singabunyamezeli kunye nonyango corticoid. Musa ukulibala ulawulo engundoqo unyango ngempumelelo - sifo kufuneka ubeke ugqirha! Kwakhona unalo ilungelo elikhethekileyo ukuqesha unyango.

Njengomnye wemiba zale sifo intsholongwane wendalo layo, kubalulekile ukugcina ubomi obusempilweni kwanawokuqhuba lukhuni emzimbeni. Kwakhona, qaphela ukuba ithuba vasculitis asakhasayo zemfuza uzimisele kwaye Musa ukusondela kwingozi engeyomfuneko.

Kwakhona, izigulane zidla nomdla kulo mbuzo: ingaba ukukhubazeka unika sifo Horton kaThixo? Njengomgaqo, nobunzima kakhulu nesi sifo kukhokelela kokukhutshwa kwalo, ngokuba kunzima ukuba esi sifo, esizibonakalisa nentloko iinyembezi, ayikuvumeli umqeshwa ukuba enze imisebenzi yabo ixesha elide, ekukhanyeni okuqaqambileyo ngokunjalo.