Medicine "Tamoxifen" umyalelo kwi isicelo sinxulumene kwiqela kweziyobisi antineoplastic ukuqalela nonsteroidal kunye antiestrogenic. Ukusebenzisa le arhente lukwakhuthaza nokukhululwa hormone yebhinqa, kunciphisa ukudumba nangempumelelo Kumiswe uphuhliso neoplasms. Ukususela ekuqaleni iibhloko ichiza ukwamkelwa inyathelo estrogen iiveki ezimbalwa, ngaphandle edala iziphumo ebezingalindelekanga ezingathandekiyo ezinxulumene imithana kwithishyu. Xa izigulane eyindoda abaphethwe ukuchama disorder, ukusetyenziswa "Tamoxifen 'ukuze bandiqumbise ukwanda plasma testosterone lamanani. Ukuba sihlolisisa pharmacokinetics yomenzeli anti-ithumba, uqala ukuba esebenzayo emva kwemizuzu nje engamashumi amathathu emva kulawulo, lwathi anelona nani liphezulu iiyure ezintlanu ukuya kwezisixhenxe.
iziyobisi Ezikhoyo "Tamoxifen" azipilisi etyheli, equlethe njengecandelo ephambili milligrams ezilishumi, amabini, amathathu okanye amashumi amane tamoxifen citrate. Ezinye izithako zezi: kwincindi, isodiyam starch, nemagnesium stearate, lactose kunye povidone. Iqokobhe iqulethe yayo ukwakheka polyethylene ethers, titanium dioxide kunye hypromellose. Ukongezelela, imali encinane ekhoyo lactose kweli chiza.
Faka iipilisi "Tamoxifen" umyalelo manual icebisa ukuba izigulane ezinochaso umhlaza endometrial, wendlala okanye amaqanda, kunye kwamadlala thoracic mammary. Kwakhona, eli yeza ziyasebenza yamathumba kwi izintso okanye wolusu. Sarcoma uyafana ukuba uqale ukuthatha ichiza "tamoxifen". Imiyalelo yokusebenzisa nowuthsi kunye neziphumo HIV ukusetyenziswa kwayo kwi unyango kwingxelo etiologies ezahlukeneyo uzlovidnyh.
Thatha le arhente antitumor akuvumelekanga ngokungqongqo kwimeko sokucalulana ngamnye citrate tamoxifen okanye naziphi na ezinye amacandelo ichiza. Leukopenia, thrombophlebitis, ukukhulelwa, ixesha zisanyisa, cataract kunye neentlobo kakhulu wesifo sentliziyo nazo Izimo ukuya kweli chiza, "Tamoxifen" - imiyalelo ukusetyenziswa pay ingqalelo kuyo. Ukongezelela, musa ukuba izigulane insufficiency hepatic okanye sezintso. Nangononophelo olukhulu kuqesha ipilisi "Tamoxifen" kunye thrombocytosis, thrombocytopenia, izifo yobuchopho, okanye hypercalcemia.
Eli chiza kwezinye amaqela izigulane kunokubangela ukungacoleki kokutya, isicaphucaphu, ukugabha, cholestasis, sinciphise ukutya, urhudo, kunye nathi afunxwe esibindini. Ukudideka, thrombocytopenia, intloko ebuhlungu, leukopenia, ukozela, umkhuhlane kunye nesiyezi inokuba nako kwenzeka ngenxa ukuthatha iipilisi, "Tamoxifen". Iziphumo ebezingalindelekanga ziquka, kunye nengozi yokuba zesibeleko ukopha, evuthayo kunye ukurhawuzelela amalungu obuni, nangezilonda esinganyangekiyo, urticaria, dermatitis kunye bronchospasm. Ngaphandle kunokuba ukuncipha iqatshelwe amandla, ngobhobhozo lobufazi, irhashalala kunye bomvu.