Ichiza "tizanidine": imiyalelo ukusetyenziswa, nye. "Tizanidine-Teva", "tizanidine-Ratiopharm"

Yintoni lwendlela ebekiweyo iziyobisi "tizanidine?" Imiyalelo yokusebenzisa le medicament okuchazwe apha. Kwakhona, ukusukela izinto zeli nqaku uza kufunda ngayiphi fomu iveliswa, kusithiwa kuthetha ukuba inxalenye yawo, ngaba iziphumo ebezingalindelekanga, kunye Izimo noogxa.

Imilo, inkcazelo, ukubunjwa

Yintoni ukwakhiwa na ichiza "tizanidine?" Imiyalelo Sebenzisa ithi eli candelo esebenzayo yale ichiza tizanidine. Kwakhona isakhiwo medicament ingqalelo iquka njengoko excipients lactose anhydrous, colloidal lesilicon dioxide, microcrystalline neselulosi kunye stearic acid.

Drug "tizanidine," apho myalelo okulungiswe ibhokisi, enziwe ngohlobo amacwecwe amhlophe ngeenxa zonke. Kwelinye icala zephetshana ungumqobo na ichiza, kwaye eyesibini - ukulabhula imigca enqamleze esiqwini T4 T2.

features kwemithi

Yintoni indlela yokusebenza "tizanidine 'iziyobisi? Imiyalelo yokusebenzisa ibonisa ukuba kukho relaxant kwezihlunu. Emva kokufumana iipilisi ngaphakathi into esebenzayo isiyobisi kunciphisa skeletal ufe kwezihlunu, bemthoba nokumelana kwabo motion eyimpumelelo deceleration yokusabela spasmodic kunye nophuculo rate ngokwesigqibo esicalanye.

Ngelithini kulula makuqatshelwe ukuba ichiza ingqalelo ikhuthaza ukusebenza kwezihlunu-kolwandle. Oku kwenzeka ngenxa yokuba ingcinezelo polisinapticheskie ingqondo lialio. Le effect kungenxa nokukhululwa acid ukusuka iiclamps (presynaptic) of interneurons lialio.

pharmacokinetic iparameters

Zeziphi pharmacokinetic parameters uye iziyobisi "tizanidine" (tablets)? Imiyalelo ukusetyenziswa kulo mba unika inkcazelo ebanzi.

Emva ulawulo yomlomo medicament ako ngokupheleleyo. bioavailability yayo epheleleyo yi-40% (ngenxa yokupasa olubanzi lokuqala kwesibindi).

I engekho mthethweni esebenzayo ezisasazwa kuzo zonke iinkqubo kunye namalaphu. kunxulumano lwayo iiproteni nama-30%.

Kwisiqingatha ubomi beziyobisi ziiyure 2.5. Malunga ne-95% ye ithamo umzimba. Wabonisa medicament ngokusebenzisa izintso (malunga nama-60%) kunye iphecana zesisu (malunga nama-20%).

Ubungqina obubonakalayo buxela

Kwezinye iimeko, amisele iziyobisi 'tizanidine? " Ukusetyenziswa kwale imithi sisebenzayo zikwimeko yiSpasticity zihlunu skeletal, olwenzeka izifo xa luvo ezifana:

• ngesibetho;
• isifo umnqonqo sisiba mandundu;
• myelopathy ezingapheliyo;
• multiple.

Kwakhona amayeza "tizanidine" eboniswe kwi buhlu- zezihlunu, ezikhula ngenxa ngokoyiswa lomqolo.

Izimo

Eyona engundoqo kwaye mhlawumbi contraindication kuphela kweli chiza yandiswa uvakalelo isigulana tizanidine. Kwakhona, oko Akuvunyelwe ukuba kubanjiswene ngeendlela ezifana "ciprofloxacin" yaye "Fluvoxamine".

Drug "tizanidine": imiyalelo yokusebenzisa

Ngokutsho imiyalelo, okokuqala idosi "tizanidine" medicament ngu 2 mg.

Ukususela isiphumo ichiza ufikelela kwincopho kwiiyure 1-2 kwaye exutywe emva kweeyure 3-6, unyango kufuneka wenziwe emva kwesithuba iiyure 6-8. Ngenxa yoko, emini kufuneka abe ngaphezulu amacwecwe-3.

Le umthamo medicament ebegqwese ukwanda ku-4 mg (ithamo ngalinye). Kodwa, ukwenza oko kuphela kwimeko ukuba, emva kweentsuku 4 unyango isiphumo uye wabonisa.

akufuneki ibe ngaphezulu kwama-36 mg idosi iyonke yemihla ngemihla ichiza. Ngokumalunga kwiiyunithi umthamo, ulwamkelo ngaphezu kwama-16 mg leengcali khange kufundwe.

• In insufficiency kwezintso. Nale uphethwe iipilisi ngokuqaphela okukhulu.
• Ukungaqheleki xa umsebenzi esibindini. isilumkiso "tizanidine" Drug kuyacetyiswa ukuba abantu babe naluphi na uhlobo sisibindi. Kwezi izigulane, idosi ngamnye kufuneka incitshiswe. Kuyimfuneko ukuba khangela rhoqo inqanaba aminotransferase. Ukubeka esweni yokuqala eyenziwa inyanga enye emva konyango.

amacala libanda

Iimpawu Clinical ezithe zenzeka ngokuchasene nentsukaphi libanda, ukuze abe Pharmacology eyahlukileyo ngokupheleleyo. Kwiimeko ezininzi, izigulane kufuneka silale, ukudideka, ukozela okanye ukuba khokhoma. Ukongeza, ichiza ngeedosi aphezulu kunokubangela kwekhono kwemisipha kwentliziyo, kuquka kukuvela bradycardia kunye hypotension.

imiphumela emibi

Ingaba kukho naziphi na iziphumo ebezingalindelekanga kubaguli abafumana "tizanidine 'iziyobisi? Imiyalelo yokusebenzisa (ntonye zesixhobo ziboniswe apha) ifundeka ukuba medicament sifundo kungabangela umlomo owomileyo, ukozela, hypotension, bradycardia, ukunciphisa uxinzelelo lwegazi, isiyezi, amahlaba kwezihlunu, ukudinwa, ubuthathaka, ukudinwa, ingqondo, hepatotoxicity, ukuphazamiseka kwesibindi.

Kakhulu enqabile baphathwe nalo eli chiza kukhuthaza imbonakalo Stevens-Johnson syndrome, dermatitis exfoliative, Njengokungeniswa anaphylactic, tachycardia ventricular, hepatitis, ukudakumba, ukuxhuzula, amalungu abe buhlungu, irhashalala, paraesthesia kunye lafa.

imithi

Ngaphambi kokuba usebenzise "tizanidine" ichiza kufuneka ufunde le miyalelo ngocoselelo. Lukhangela mpawu zilandelayo neminye imithi:

• Nodibaniso 'ciprofloxacin "yaye" Fluvoxamine "kunganciphisa kakhulu uxinzelelo lwegazi, kwaye kananjalo ukuphuhlisa ubuthongo. Ukongeza, amalungiselelo ezintsonkothileyo iphula imisebenzi lengqondo abantu.
• iyeza unyango ngaxeshanye kunye inhibitors CYP1A2 (umz: "zileuton" "Fluoroquinolones", "Amiodarone", "Mexiletine", "propafenone" "Verapamil," "Cimetidine" "Famotidine" "acyclovir" yaye "ticlopidine") ngokungqongqo contraindicated.
• Akunconywa iipilisi edityanisiweyo "tizanidine" kunye zokucwangcisa ngomlomo. Ukuba imeko yangoku isigulane kufuna ulawulo ngaxeshanye la mayeza, idosi lokuqala kufuneka ibe ncinci. Ulwamkelo ngeedosi eziphezulu beziyobisi kungakhokelela ekubeni iziphumo ebezingalindelekanga ezifana hypotension, bradycardia kunye hypersomnia.
• Dibanisa eli chiza yotywala ayikhuthazwa. Oku kungenxa yokuba utywala kwandisa xi ukwimo isiyobisi esebenzayo egazini, kwaye oku kungakhokelela ekubeni iziphumo ezingafunekiyo.

iimeko ezikhabhathini, ukugcinwa kunye nokuthengiswa

Tablets "tizanidine" kwabiwa Pharmacy kagqirha kagqirha. Kufuneka ibe kwiqondo lobushushu igumbi kwindawo emnyama. Kuyimfuneko ukukhusela ichiza ebantwaneni abancinane.

Ubude bethuba ubomi mali leyo iminyaka emi-3. Emva kweli xesha ke akuvumelekanga ukuba.

Price, ntonye kunye analogue beziyobisi

Amachiza ezahlukeneyo ezifana "tizanidine," "tizanidine Ratiopharm" yaye "Teva tizanidine?" Imiyalelo yokusebenzisa ezi ndlela iqulathe izikhokelo ezifanayo, iziphumo ebezingalindelekanga, Izimo, iindlela zolawulo kunye iidosi. Umahluko kuphela phakathi amayeza kuyichaza abenzi zabo. Ngoko ke, zonke ezi iimali ingqalelo eyodwa.

Njengoko kuba ekhethekileyo "tizanidine" iziyobisi, ngoko ke zibandakanya iziyobisi ezifana "Sirdalud", "Tizalud" yaye "Sirdalud MP."

Ingaba yimalini "tizanidine," "tizanidine Teva" yaye "tizanidine Ratiopharm"? IMimiselo ehlonyelwe la machiza, akaphenduli lo mbuzo. Ukuze ukwazi ixabiso yezi ndlela uya kuba nako ukulwa kuphela. Ngokuqhelekileyo, akukho eliphezulu kakhulu kwaye imalunga 120-170 engange Russian (kuxhomekeka kwinani iipilisi uqiniseke kunye yakowayo).

Kufuneka ngoko nangoko kuqatshelwe ukuba medicament "tizanidine" luneendleko ayibizi kakhulu (umzekelo, analogs ezifana "Sirdalud", "Tizalud" yaye "Sirdalud MR" zibiza kancinci, malunga 240-270 engange). Yiloo nto izigulane ezininzi iqala inike babo siyobisi sokuqala.

Reviews imithi

Ngoku uyazi ukuba kutheni amisele iziyobisi ezifana "tizanidine," "tizanidine Ratiopharm" yaye "Teva tizanidine." Umsebenzisi Ukwamkelwa kwezi arhente sele uchazwe apha ngasentla.

Izigulane ezisanda ukhe wayisebenzisa le amayeza, bawuthwale ngeendlela ezahlukeneyo. Uninzi reviews kwenza kube lula ukucinga ukuba ichiza "tizanidine" alusoloko ukuhlangabezana nokulindelweyo zezigulane.

Abantu abaninzi bathi ukuba eli chiza kwenye namatyala amathathu zinokubanga iziphumo ebezingalindelekanga ezifana amahlaba kakhulu kunye nobuhlungu bomzimba. reactions ezifanayo zenzeka ngokukhawuleza emva kokuba isicelo le medicament.

Emva ngokusebenzisa amacwecwe yesibini, ezinye izigulane ndiba buthathaka, unesiyezi, kwaye siyanibongoza ukuba agabhe. Xa iimpawu ezinjalo, iingcali bacebisa ukuba uyeke ukufumana imali, okanye namandla nande.

Kwezinye iimeko, emva kokusebenzisa "tizanidine" abantu abanengxaki kwengcinezelo kunye nesisu, kunye iyangongoza intliziyo.

Kufuneka kuqatshelwe ukuba ingxelo entle evela ichiza phantsi kovavanyo ayikho kangako. Phakathi kwazo ukufumaneka kunye neendleko eziphantsi na ichiza.

Ngenxa yoku kufuneka kugqitywe ukuba ukuthatha amayeza "tizanidine" kunye ntonye zalo, kuphela ukuba kuboniswe kwaye kuphela kagqirha.

Njengoko inani elikhulu reactions ezibi, iingcali ayikhuthazwa ukusebenzisa iziyobisi ngexesha lokukhulelwa ngexesha ibele-ibele, kungenjalo kusenokuba yingozi kwimpilo wosana okanye usana olungekazalwa.