Glatiramer acetate: izinto inkcazelo

multiple - a umonakalo omkhulu kwindlela luvo kusoloko ukuphathwa. Isifo abantu bangenwe abaselula phakathi yobudala: abasemngciphekweni libandakanya amadoda nabafazi ukusuka kwiminyaka eli-15 ukuya kuma-40. Enye indlela asetyenziswa uphathwa acetate glatiramer. On kuya kuxutyushwa kweli nqaku.

sclerosis Multiple: iindlela, oonobangela, iimpawu

A isici esasenza sifo kwezinye izifo kukuba kuchaphazela iinxalenye eziliqela e-nervous system, wagaleleka kuyo isigulane ebonisa iimpawu ezahlukeneyo luvo. Nokucima multiple ikhona ukuba: alternating amaxesha exacerbation kunye noxolelo.

Umfutho Uphuhliso kwesi sifo ukutshabalala inwebu-luvo esengqondweni kunye umnqonqo, nto leyo sclerosis (amaziko) ukuyilwa umonakalo. ubungakanani zawo ukusuka milimitha ezimbalwa ukuya ngokweesentimitha eziliqela. Xa exacerbations badla imfundo umonakalo ingakumbi enkulu.

Ukuza kuthi ga ngoku, unobangela esi sifo ayiqondwa ngokupheleleyo. Noko ke, kukholelwa ukuba multiple kubangelwa yi indibanisela iimeko zangaphandle nangaphakathi. To ezo ziquka:

• Susceptibility izifo (wentsholongwane egazini kunye bacteria).
• Ukuboniswa kwezinto kwimitha kunye izinto eziyityhefu.
• Ukungondleki.
• yokuhlala Geoecological.
• ukulimala rhoqo.
• iimeko rhoqo uxinezeleko.
• yofuzo.

symptomatology

Uxilongo senziwe luvo ukuba iimpawu zenzeke:

• Lafa izandla, imilenze kunye nomzimba. Isigulana kunzima ukubamba ezandleni zabo izinto, nokuba nkqu ngecephe okanye ngepeni.
• Incoordination.
• Nystagmus - okukhawulezayo, iintshukumo iliso kungalawuleki.
• Kuncipha (okanye epheleleyo Ukunyamalala) ingqondo.
• Utshintsho ezithandwa ukungcamla, ukwehla kobunzima bomzimba.
• Ndindisholo, ubuthathaka imilenze.
• Isiyezi kunye nezinye ukwaphulwa vegetososudistye.
• Paresis le luvo yobuso kunye trigeminal.
• Namandla ngabantu, ukuphazamiseka exesheni kwabasetyhini.
• Nciphisa kwi acuity olubonakalayo.
• intetho Slow.
• Dysmotility.
• izifo zengqondo (ukudakumba, imincili, njalo njalo.).
• sokuwa.

imilo

Kukho iintlobo ezintathu multiple:

• Cerebrospinal - i ixhaphakileyo. Luphawulwa ukwenzakala nisaqala isifo mba ezimhlophe kuzo zombini umnqonqo nobuchopho.

• Cerebral - ekubulaleni lomba emhlophe zobuchopho. Oku kuquka iintlobo ezininzi - cerebellar, isiqu, uthinte amehlo.

• Spine - sisilonda esidumbileyoesingaphakathi spinal.

Glatiramer acetate in multiple

medicament Izincomo kunxulumene kwiqela immunomodulators. Imele ityuwa uskusnokisluyu kwasekwa acid yendalo L-tyrosine, L-glutamic acid, L-alanine, L-lysine. Olu tshintsho iziyobisi ngexesha sifo, kuba isiphumo immunomodulatory yasekuhlaleni. Ukusetyenziswa glatiramer acetate nangokuchanekileyo ngexesha noxolelo, kuba kulo mzekelo kuthetha kunciphisa nezihlandlo exacerbations kwaye abangaphangeliyo uphuhliso ukuphazamiseka luvo.

Ubungqina obubonakalayo buxela

Iimpawu zokusetyenziswa ichiza ayikho kakhulu. Ezi ziquka:

• Nokucima multiple. Kulo mzekelo, acetate glatiramer isetyenziselwa ukunciphisa exacerbations kunye deceleration yeengxaki sifo isici.
• Ngokwezonyango zodwa Syndrome, kokuqhubela phambili corticosteroids efakwa ngaxeshanye nokudumba ngokukhawuleza ezifunekayo. Ngelo xesha linye amayeza emiselweyo kusetyenziswa isantya nokutshintshwa sifo kwindawo multiple ezichongiweyo ngokucacileyo.

Izimo

Njengoko kunjalo kunye amayeza ezininzi, ukusetyenziswa glatiramer akuvumelekanga:

1. Ukuba isigulane hypersensitive ukuba ichiza (kuquka mannitol).
2. Ngethuba lokukhulelwa zisanyisa.
3. Ukuya kutsho kwiminyaka eli-18 ubudala (ukusebenza kunye nokhuseleko azikhange kufundwe).

Ukongeza kwezi Izimo, kukho imida. Umzekelo, ukuba isigulana umntu ukuthambekela iintlobo ezahlukeneyo komzimba, kwakunye ezimbi inkqubo yokujikeleza kunye nokuphazamiseka olusebenzayo izintso ukusetyenziswa kweziyobisi kunokwenzeka, kodwa kuphela kwiimeko kakhulu kwaye phantsi kweliso zonyango.

imiphumela emibi

reactions Ezingalunganga ukuba ukusetyenziswa kweziyobisi ngokusekelwe into efana glatiramer acetate, ezininzi ezahlukeneyo. Ngoko ke, ukuba yahlulwe ngamaqela:

1. System Immune: hypersensitivity, ukothuka anaphylactic, angioedema.
2. inkqubo Hematopoietic: kukuvela izifo ezifana leucopenia, leucocytosis, lymphadenopathy, utshintsho kubume lymphocyte, thrombocytopenia kunye splengomegaliya.
3. inkqubo yonyango: hyperthyroidism.
4. Luvo: intloko kunokwenzeka, ukudakumba, ukuxhalaba, uvalo, imincili, unditsho, umsebenzi motor kakuhle, badengeka, njalo njalo.
5. Ukusuka a yokucola ukutya: oku inokubonakalisa njengoko ukwanda ubunzima emzimbeni, nokuba unesifo. Ukongeza, kusenokubakho hyperlipidemia, hypernatremia, sifo.
6. Ukuva ilahleko, intloko.
7. Amalungu yombono: diplopia, umonakalo kwenwebu yamehlo, cataract, yoma optic, isiphene entsimini wombono, ukungaboni.
8. nemithambo yegazi: tachycardia, tachycardia paroxysmal, imithambo varicose, noxinzelelo lwegazi.
9. inkqubo yokucola: isicaphucaphu, ukugabha, ukudumba, belching, ukopha efakwa njalo njalo.
10. isixokelelwano sokuphefumla: ukukhohlela, nokuthimliswa yamaxesha onyaka, ukuphelelwa umoya, hyperventilation. Laryngospasm.
11. Isibindi kunye biliary ngeendlela: cholelithiasis.
12. inkqubo wokuchama: pollakiuria, hematuria, ukugcinwa womchamo.
13. inyama ongama isikhumba ukurhawuzelela, qhagamshelana dermatitis, urticaria, erythema nodosum njalo njalo.
14. Musculoskeletal System: arthralgia, iqolo nentamo, samathambo, bursitis, osteoarthritis, njalo njalo.
15. Sangasese glands mammary: sexesheni, nande umhlaza webele, erectile kwekhono.
16. Ukugodola, ukudinwa, ukopha ngeempumlo, ifiva, ukudumba, amaYiputa abephathe iingono njalo njalo. Iimpawu.

Ukudibana ne Drug

Umbuzo esebenzisa yentsebenziswano ngokusekelwe glatiramer acetate kunye nezinye iziyobisi khange kufundwe de kube sekupheleni. Ukusebenzelana ukusetyenziswa ngaxeshanye kunye namachiza asetyenziselwa ukunyanga sclerosis, noko kutyhilwa (zisekelwe ekusetyenzisweni ahlangeneyo ama-arhente ngentla iintsuku 28). okuba High of ziyabagulisa yasekuhlaleni.

libanda

Ukuza kuthi ga ngoku, iinkcukacha iziganeko ezibi kunye libanda, beziyobisi ayikho. Ukuba yonke inkathazo efanayo kwenzeka, isigulane kufuneka abe phantsi kweliso elibukhali likagqirha abasenyongweni. Ukuba imeko jikelele yomguli, kwakunye nokunika unyango kwangumqondiso nezixhasayo.

Glatiramer acetate: imiyalelo yokusebenzisa

20 mg ye kwesikhumba ezilawulwa iziyobisi kanye yonke imihla. Uyacetyiswa ukuba kwishedyuli: inaliti Kucetyiswa ukuba ngexesha elifanayo. Ukuba nangasiphi na isizathu ukuqeshwa liphosiwe, ngoko ichiza sizakungena ngokukhawuleza nje ukuba ukhumbule. A sizifombe akumele ukuhlatywa.

iziyobisi alawulwa ngurhulumente avunyelwe ezimpundwini, iinyonga, nezandla kunye nesisu (isithuba paraumbilical kumgama we-5 cm). Imimandla isikhumba anozizi kwaye olumbhatshileyo kunye neendawo ngamatywina iinaliti musa ukubeka. Thatha isigqibo sokunqanda unyango kufuneka ube ngugqirha.

ukusebenza

Ingaba glatiramer elungileyo acetate? Ukuphonononga eziqulathe ulwazi malunga neziphumo sisebenzayo nisaqala ekulweni multiple. Abantu abaninzi wehlelwa ziziphumo ebezingalindelekanga ngoko nangoko emva isitofu beziyobisi. Noko ke, ixesha elifutshane kunye zona ngokwazo. Ukuba ngaba wehlelwa iimpawu kakhulu, ngoko nangoko udibane nogqirha, kwaye kwezinye iimeko - mema inqwelo yezigulana.

Kwiimeko ezinqabe kakhulu, ulawulo ezingapheliyo beziyobisi inokuba wesikhumba necrosis kunye lipoatrophy kuyo inaliti. Ukuthintela iziphumo ezinjalo kufuneka ulandele kuphela ukulandelelana amalungu omzimba ukuba ngenaliti.

Igama Trade, umenzi

Glatiramer acetate unalo igama elahlukileyo lorhwebo. Kodwa kamva kulo. Kangangexesha elide, ngaphambi kokupheliswa kwesivumelwano kunye inkampani, lomthengisi Teva, iimveliso wona athengiswa Ltd. "Biotech". Glatiramer acetate ngoku ukhona ngapha ezininzi Teva inkampani Russian "Teva".

Ngokuqesha ichiza ngenxa sclerosis, ugqirha rhoqo iya kubonisa igama recipe kuyinto: "Copaxone Teva." Noko ke, le kuphela kwendlela, iyeza engundoqo esebenzayo i acetate glatiramer. Analogs kugcwele, ezi ziquka:

• "Copaxone 40".
• "Glatirat".
• "Aksoglatiran FS".
• "Timekson".

Yintoni umahluko lithetha "Copaxone Teva" yaye "Copaxone 40" Enyanisweni, omnye kunye efanayo ndlela? Le into esebenzayo kuwo ngokulinganayo - acetate glatiramer. Izithethantonye oyidlayo ezahlukeneyo kungoko ixabiso lentengiso.

Yiba ingqalelo impilo yabo, ngexesha ukuya kugqirha kwaye uthathe unonophelo omthandayo!