Amalungiselelo Digitalis: ezibonisa kunye neziphumo kweli izifo inhliziyo

Digitalis - bohlobo kwezityalo eneentyatyambo, ezisetyenziswa njengeyeza zezigulo zentliziyo.

Malunga kardiotropnyh iimpawu le ntyatyambo Kudala kwaziwa. Kwisiqingatha sokuqala senkulungwane XVIII, oko yaqala ukukhula eRashiya emyezweni avumba limnandi, kwaye ukusukela ngo 1775, xa ekupapashweni imisebenzi yezonyango Uayteringa yaseBritani, digitalis amalungiselelo baye ngamandla indawo ukusebenza unyango izifo zentliziyo.

Ezona mpawu ngezityalo digitalis

Rhode foxglove (Digitalis) - izityalo kweentyatyambo ezi plantaginaceae usapho ongatshiyo kunye inflorescences ezinkulu thimbles ezifanayo iintyatyambo kunye namagqabi ubuncwane ukushwabana. Bloom phakathi ku-ehlotyeni (ekupheleni kukaJuni-Julayi), iziqhamo - iibhokisi yokusonga zamaqanda-ezimise nge iimbewu ezincinane omdaka. naperstyanok lilonke wachaza iintlobo 36 zisetyenziselwa iinjongo zonyango 5 kuphela: lanata digitalis (mthombo uphambili of raw materials), neengubo ezimfusa, ciliated, kunye grandiflora ngekopi.

Ekuqaleni lanata digitalis iziyobisi yaba sisicatshulwa esithathwe amagqabi kunyaka wokuqala nowesibini. Okwangoku, glycosides namayeza afanelekileyo digitalis efunyenwe kwiindawo ezonga izityalo, ukuchetywa phambi lokudubula kweentyatyambo.

Zonke foxglove enobuhlungu, ebonisa ukuba inani elikhulu kwezinto eziphilayo esebenzayo kufuna ukuphathwa ngenyameko.

Amacandelo yemichiza isicelo foxglove

Imithi Digitalis ziquka izithako yayo engundoqo esebenzayo - glycosides kwentliziyo: digitoxin, gitoksin, digoxin, atsetildigoksin kunye nabanye abaninzi, kwakunye asidi eziphilayo, saponins, flavonoids.

Uninzi components esebenzayo abe imvelaphi hydrolytic zasesekondari, ngamanye elifunyenwe cleavage enzymatic neemolekyuli yendalo glycosides.

iziyobisi digitalis esetyenziswa ukunyanga izifo ezininzi kwentliziyo, ikakhulu enxulumene lokunciphisa iimpahla intliziyo negazi:

1. ukusilela Heart nangokujaduka eziphilayo ezahlukeneyo izakhiwo intliziyo (kubandakanywa njengenyathelo lokuthintela).
2. Izifo kwemithambo yenhliziyo ezikhokelela decompensation.
3. fibrillation Atrial.
4. Nangokurhala, ukonakala kwazo imisipha yenhliziyo.
5. Paroxysmal tachycardia e abafazi abakhulelweyo.
6. Ukulungiselela utyando intliziyo.

Xa ukunyhashwa inkqubo kwentliziyo Uhanjiso (block) kunye glycosides bradycardia digitalis hayi ababelwe.

Njani le glycosides digitalis ichiza

Lineminyaka ingca digitalis glycosides ifuthe ngqo kwi imisipha intliziyo. Xa ukusilela intliziyo, isiphumo sesicelo digitalis imi ngolu hlobo lulandelayo:

• ukuncipha izinga intliziyo;
• kwandisa amandla contractile engabalulekanga;
• kululwa isithuba ukunyenyiswa entliziyweni (diastole).

amalungiselelo digitalis ziye zasetyenziswa xa unyango ukusilela yokujikeleza, xa intliziyo akakwazi ukumelana nokukhuthazwa imithambo yegazi, nto leyo nzima nokudumba nokuphazamiseka trophic ngempumelelo. Kulo mzekelo, ziziyobisi glycosidic kulindeleke ukuba:

• ukwandisa imveliso wentliziyo (isixa wegazi ephuma ventricles zokunciphisa nganye);
• yokulahla ngempumelelo ngaphezulu ventricles ngexesha systole;
• nokuncipha umthamo wegazi elijikeleza kwiinqanawa, ngenxa yoko, kunciphisa ukudumba;
• kuqheleke izinga kwentliziyo tachycardia;
• ukukhawulezisa wegazi flow ebhedini nemithambo;
• kwandisa ilizwi semithambo, nto leyo sikhatshwa ukunyuka okungephi uxinzelelo lwegazi.

Digitalis unokuba bandiqumbise kunganqwenelekiyo ukuba iziphumo ebezingalindelekanga ukuphazamiseka phecana zesisu, luvo, utshintsho izinga intliziyo. Ukusetyenziswa olungagunyaziswanga kula machiza ayamkelekanga, irejimeni yonyango ugqirha ukhetha isigulana umntu wanikwa kuphela.

Iziyobisi foxglove zoboya

"Tselanid" - glycoside kwentliziyo inyathelo ngokukhawuleza evela ngokohlobo iipilisi kunye isisombululo inaliti efakwa. The main ezibonisa - ukusilela yokujikeleza, tachycardia, fibrillation atrial.

"Digoxin" luphawulwa kukwanda contractility engabalulekanga, oko kungqubana isasazwe coronary yaye kunciphisa kudumba ngenxa yeziphumo umchamo. Yegazi kunye ngomlomo. Oku kuboniswa zezigulo kakhulu yegazi kwaye ngexesha kokuhlaselwa tachycardia paroxysmal kwi likaxakeka.

ukusebenza therapeutic ifikelela ubuninzi emva kwexesha xa into esebenzayo emzimbeni bafikelela yoxinaniso ethile. Kukho ubukela (nokwanda) ngenxa yokuba digitalis amalungiselelo avela kancinci.