Alpha-fetoprotein kwiimeko eziqhelekileyo kunye zophendlo lwezifo

Alpha-fetoprotein kuyinto material leeprothini imvelaphi evela kwi sac bemveku emva kokuzalwa - kule wokugaya kwaye iiseli esibindini. Ngokuqhelekileyo, ikhoyo nokubakho emzimbeni 15 ng / ml.

Alpha-fetoprotein uzimisele ngexesha ukhulelwe ukuba ukufumanisa iziphene yosana olungekazalwa. Uyifumane inkcazelo isicelo isalathisi kunye Oncology. Alpha-fetoprotein yi oncomarker umhlaza wamatyhalarha kunye wesibindi. Malunga 70% yamadoda kunye yamathumba wamatyhalarha na eziphakamileyo, ingakumbi inkqubo Ukudlulela.

Ekuqaleni, oko into protein kuhlelwe kwi zamaqanda, lo luteum corpus. Kule veki yesihlanu, ingane uqalisa ukuvelisa zalo. Alpha-fetoprotein ukhusela Umbungu ukusuka kwinkqubo sikanina omzimba, apho yena a arhente zasemzini.

Ayithandi yaligqiba kuyinciphise, njengoba igazi imveku kunye negazi koomama. Ixabiso eliphezulu le parameter ngenxa uxilongo - xa kwiiveki 12-16. Xa kwiiveki 32-34 zokukhulelwa lifike kwinqanaba eliphezulu kumagama-fetoprotein. norm kwabantu bephilile ifunyanwa kunyaka wabo wokuqala bezelwe.

yenze uphando ezichaphazela ngokuphawulekayo kwenkcazo isalathisi. eyamkelekileyo ukungaqheleki nokonyulwa alpha-fetoprotein yaba ubuninzi angumndilili (umama). Amanqaku angumndilili inani eliphakathi we amaxabiso wayalela leeprothini yoxinaniso ekukhulelweni eqhelekileyo ngaphakathi kule kota. Ngaloo ndlela, umntu akwazi ukuthelekisa, ukukhulelwa alpha-fetoprotein kwizigaba ngezigaba ezahlukeneyo, kwaye kananjalo hlalutyo lululo wenza bokuba ezahlukeneyo. Amanqanaba yale isalathisi ukususka kwi 0.5 ukuya 2.5 umama kuqhelekile.

Ukwandisa AFP zingaba uphawu of:

• Yamathumba le bronchi.
• metastases Isibindi.
• Umhlaza isisu, injeke, umphunga, isibindi, ikholoni, webele.
• wamatyhalarha osandul kunye nangezilonda ovarian.

Okwethutyana yaye ingaphantsi nokwanda alpha-fetoprotein kule ezimbi zilandelayo:

• Isibindi kwesibindi,
• ukusilela kwesibindi Chronic,
• Alcoholism phambi kwesibindi yokulimala,
• hepatitis viral ezinganyangekiyo okanye bukhali.

Eli nani lanyuka ngexesha lokukhulelwa luvela kwezi meko zilandelayo:

• ukukhulelwa ezininzi.
• isifo sezintso kule olungekazalwa.
• Ithemba yosana kwi olungekazalwa.
• isibindi necrosis Fetal.
• Malformations ye uvaleke (rahishizis, anencephaly).
• Emqhokrweni udonga ngaphambili esisu yosana olungekazalwa.
• Okunye malformations.

Noko ke, kunciphise alpha-fetoprotein ngexesha lokukhulelwa ukuze abonise oku kulandelayo:

• ukukhulelwa mavunwa.
• ukulibaziseka Developmental.
• ukufa Fetal.
• ukukhulelwa izinyo.
• isisu okuzenzekelayo.
• Trisomy of chromosome 18 okanye 21.

Ukufumaneka yehlise alpha-fetoprotein kunokubonisa i ukuzimisela olungachanekanga ubude ukukhulelwa, oko kukuthi, ukukhulelwa kwenzeka kamva.

Xa ne G kwi langoku nqanaba primary isibonisi isiphawuli esebenzayo ukuphazamiseka chromosomal ezingekazalwa kunye ezimbi zokukhulelwa. Ukutenxa uphuhliso eziqhelekileyo foetal Ndiyijike xi eqhelekileyo kwezinto iiprothini egazini sikanina. Kakade ke, kufuneka ube nje kwinkcazelo zesi salathisi, njengoko kunjalo ulwazi. udinga ukuba baqhube izifundo ultrasound, eyenza kube lula ukuqinisekisa inkcazelo eyiyo kwekota, ukukhulelwa ezininzi njalo njalo. Kwakhona, kubalulekile ukuba ukuchonga hormone placental (chorionic gonadotropin kunye estriol free), ukuvumela kuvavanyo echanekileyo inkqubo fetoplacental. ile yabo alpha-fetoprotein uchazwa kuvavanyo triple okuvumela ukumisela umngcipheko iindidi malformations kwi olungekazalwa.