"Paglyuferal" Amacwecwe: imiyalelo ukusetyenziswa, analogs kunye nohlolo

Abantu abanengxaki sokuwa kufuneka rhoqo ukuthatha amachiza antiepileptic. Banceda iyaluthintela uphuhliso sokuwa, ngokunjalo nokuphucula impilo jikelele kunye kwimeko yomguli.

Hlobo luni iziyobisi kufuneka ingasetyenziswa kwizigulane kunye sokuwa, kufuneka amisele kuphela ugqirha onamava. iziyobisi "paglyuferal" libhekisela anticonvulsants ezisebenzayo nezaziwayo. Imiyalelo zokusetyenziswa ichiza ziza kuchazwa ngezantsi. Uza kufunda kuhlobo ichiza ukuze ithengiswe, ngaba kunokwenzeka ukunika abantwana bakhe, yintoni iipropati ngayo, njalo-njalo.

Inkcazelo, ukupakisha, ukwakhiwa kunye nefomu

Ukulungiselela manual "paglyuferal" ukuqeqesha uqulathwe iipakethi amaphepha, iya ithunyelwa ngohlobo amacwecwe emhlophe beveled kunye Valium.

Isixhobo iqulethe izithako ezisebenzayo ezifana phenobarbital, caffeine sodium benzoate, bromisoval, calcium gluconate kunye papaverine hydrochloride. Njengoko ngokuba excipients, ngoko ke ziquka neetapile starch kunye calcium stearate.

Thenga eli chiza banokuba namadyungudyungu kunye iipakethe zephepha shinyi, ngokulandelelana.

Kufuneka ube nangoko kuphawulwe ukuba ezishelfini abantu ezikhemisti ukulungiselela inokufumaneka kwi la magama alandelayo: "paglyuferal-1", "paglyuferal-2" kunye "paglyuferal-3 '. Imiyalelo yokusebenzisa ingxelo ukuba umahluko phakathi indlela leyo elingqamene phenobarbital (25, 35 no-50 mg, ngokulandelelanayo).

Pharmacology

Yintoni na ichiza 'paglyuferal "? Imiyalelo yokusebenzisa (tablets kufuneka ilawulwe kuphela specialist abanamava) ithi ukuba siyobisi antiepileptic zidityanisiwe.

Ngokutsho ubugcisa, ekwaziyo zakudibana phenobarbital "barbiturate 'isahlulo Gaba-benzodiazepine receptor complex. Ngenxa yoku, ingqalelo ichiza kwandisa uvakalelo ka Gaba receptor ku Gaba kwaye ayityhilele amajelo neuronal ngokuthutha kwazo ion chlorine, ukuze kwandiswe ukusebenza kokungena kwawo iiseli.

Kwakhona phenobarbital kunciphisa andise neemvakalelo-luvo kunye excitability iineuron kujoliswe sokuwa. Liveza nokubanga ngokuchasene inani neurotransmitters excitatory.

Ziziphi ezinye iipropati lokuba iipilisi "paglyuferal 'na? Guide ingxelo ukuba bayakwazi ukucinezela neuron oluvo, ukunciphisa umsebenzi iimoto, zinqanda umsebenzi ebuchotsheni, kuquka iziko sokuphefumla. Kwakhona, eli chiza lihlisa ithoni izihlunu wokugaya, iye antispasmodic, sine thile kunye nesenzo antispasmodic.

iimpawu imithi

Ukongezelela Phenobarbital, kwi indlela ingxelo kuquka nezinye izithako ezisebenzayo.

Yintoni indima caffeine kwimveliso 'paglyuferal "? Imiyalelo yokusebenzisa lubonisa ukuba into unoxanduva ukwandisa excitability reflex ye umnqonqo, afunzele amaziko vasomotor kunye zemiphunga ukukhuthaza iinkqubo pathways zomzimba kunye namaziko, kuquka izihlunu kunye nenkqubo luvo.

hydrochloride Papaverine liyindlela antispasmodic. It has a isiphumo iqinile. Eli candelo ubunjwe ichiza kwaye kucutha ufe zihlunu egudileyo buyasikhulula imithambo yegazi kunye nezibilini.

Calcium gluconate uyakwazi bavale yokunqongophala ion calcium, leyo kubalulekile ukugqithisa luvo uyibona.

Yona bromisoval, asinto ibe nafuthe eliphakathi thile kunye umthomalalisi.

iipropati kinetic

Oku bafakwa ichiza yegazi "paglyuferal-1 '? Imiyalelo yokusebenzisa ibonisa ukuba icandelo ngalinye esebenzayo eli chiza iimpawu zayo entshukumo.

• Phenobarbital ako ngokupheleleyo, kodwa (iiyure ngaphakathi 1-2) kancinci. umzimba wayo esibindini. Isiqingatha-kubomi beli candelo iintsuku 2-5. Yena ibonakala umzimba nezintso.
• Caffeine ako kakuhle kulo amathumbu. Le xi liphezulu iziyobisi iyazalisekiswa emva kwemizuzu 50-75. It umzimba esibindini mazwe nge nezintso.
• Umyinge bioavailability yi 54% of papaverine. Ekubeni sibopha kwiiproteni plasma nge-90%. Lokugaya kwenzeka esibindini, kwaye imveliso ngokusebenzisa nezintso.
• Malunga 1/5 we idosi ikhalsiyam gluconate ifunxwe emathunjini amancinci. Malunga nama-20% kwemichiza yi nge izintso abanye - kunye endleni.

ubungqina

Zeziphi izifo amisele loo neziyobisi "paglyuferal-2"? isicelo Umsebenzisi ithi ukuba oku kuba unyango lwe ukuxhuzula.

Izimo

Zeziphi Izimo ezisegumbini iziyobisi 'paglyuferal "? Imiyalelo zokusetyenziswa (ezisanda kuzalwa esi sixhobo asikusebenzeli ukumisela) iingxelo nezithintelo zilandelayo:

• hyperkinesis;
• isibindi kakhulu yaye ukusilela kwezintso;
• myasthenia gravis;
• ukuxhomekeka iziyobisi;
• ukudana;
• igazi kakhulu;
• hyperthyroidism;
• porphyria;
• utshwala esebenzayo;
• diabetes;
• nokukhulelwa;
• hypoadrenalism ;
• zisanyisa;
• isifo broncho-obstructive;
• hypersensitivity.

iziyobisi Antiepileptic emacwecweni ezilawulwa abantwana ukusuka kwiminyaka emithathu ubudala. Ngenyameko kucetyiswa ukuba abantu elibuthathaka (ngokubanzi).

Drug "paglyuferal": imiyalelo yokusebenzisa

medicament kubhekwe ilawulwa ngomlomo emva kokutya. Le yedosi kuxhomekeke kwifom release.

Iziyobisi "paglyuferal-1" kunye "2-paglyuferal" athathe kabini ngosuku ":

• kwiminyaka 3-4 - 1 tablet;
• emihlanu okanye emithandathu iminyaka ukuba amacwecwe 1.5;
• esixhenxe ukuya neminyaka esithoba - 2 iiPC;.
• elishumi elinamine kweminyaka - 3 no 2.5 pc. ndiela;
• kweminyaka elishumi elinamine, - 4 iiPC.

Medicament "paglyuferal-3" Kwakhona thatha kabini ngosuku:

• esixhenxe ukuya neminyaka esithoba - 1 tablet kabini ngosuku;
• elishumi elinamine kweminyaka - 1.5 amacwecwe;
• kweminyaka elishumi elinamine - 2-PC.

imiphumela emibi

Ukwamkelwa ingqalelo ichiza kungabangela:

• saka, ubuthathaka, isiyezi, nystagmus, Ataxia, dysarthria, ukuphazamiseka kokulala, ukusabela ngamazwi;
• kwesisu, isicaphucaphu, urhudo, eziphakamileyo transaminases isibindi, ukugabha;
• thrombocytopenia, agranulocytosis, igazi megaloblastic;
• tachycardia, utshintsho uxinzelelo lwegazi, arrhythmia, fibrillation, AV kwamabutho;
• ukusabela systemic negazi, ukuxhomekeka iziyobisi (ulawulo ezingapheliyo).

Iimpawu libanda

amathamo aphezulu medicament kunokubangela reactions icala yokukhulisa. Ukuphelisa ezi mpawu kusebenza:

• lavage esiswini;
• symptomatically;
• indlela wamalahle yasebenza.

imithi

Unyango izigulane abafumana valproate kunye "Phenytoin" imigangatho kwandisa serum of phenobarbital.

"Paglyuferal" uyakwazi zinqanda isiphumo zokucwangcisa zomlomo kunye salicylates.

Nodibaniso 'reserpine "isiphumo phenobarbital wande, yaye xa zidibene ne" Amitriptyline "" Diazepam "," chlordiazepoxide, "" nialamide "yaye" acetazolamide "- ucutho.

Le medicament "paglyuferal" GCS kunciphisa igazi kunye anticoagulants, "Doxycycline", "griseofulvin" estrogen kunye nezinye arhente leyo bangenele igcwala esibindini.

Eli chiza abangaphangeliyo sisenzo sulfonamides, umsebenzi antibacterial nokubola isiphumo "griseofulvin". Ngapha koko, oku potentiates iimpembelelo neuroleptics, ethanol, analgesics ezidakumbisayo, relaxants kwezihlunu, hypnotics kunye nadlamkisayo.

Nokubuyekezwa analogue

Ngokutsho ubugcisa, ichiza uchaphazelekayo ekhethekileyo, efanayo kumafa. Ngoko ke, endaweni kunye isigulane kufuneka udibane i nogqirha onamava.

Abasebenzisi bathi ukuba athenge le iyeza ngaphandle kagqirha kagqirha ayisebenzi, nangona kakhulu efikelelekayo.

Abantu abathatha eli chiza antiepileptic rhoqo, wathi isiphumo yayo emihle. Noko ke, abanye babo ukhalazela ukuvela kukho inani elikhulu yeziphumo ebezingalindelekanga.