"Monosan": imiyalelo ukusetyenziswa, nabalingani real

Kutheni yaye yintoni umthamo ebekiweyo ichiza "Monosan"? Imiyalelo yokusebenzisa iziyobisi vasodilator ichazwe ngokwenkcukacha izinto kweli nqaku. Kwakhona siveza analogs medicament, ukwakhiwa kwayo, iziphumo amayeza, Izimo, iziphumo ebezingalindelekanga, njalo-njalo. D.

Imilo, ukupakishwa, ukubunjwa

Ziziphi izinto ziyinxalenye ichiza "Monosan"? Imiyalelo ithi ukuba element yangoku yale ichiza isosorbide-5-mononitrate. Kwakhona, lo medicament liquka sisincoko kunye okunye ezinjalo: lactose talc granulated, nemagnesium stearate, microcrystalline neselulosi nengqolowa istatshi.

Ziziphi abenzi ifomu ukuvelisa ichiza "Monosan"? Imiyalelo zokusetyenziswa ithi ukuba ichiza zingathengwa kuphela ngohlobo iipilisi. Aselemhlophe kwaye lwayinqila ngeenxa imilo. Kwelinye icala cwecwe kukho ingozi.

Ichiza lupakishwa namadyungudyungu, apho ibekwe mfumba emiba.

features kwemithi

Njani ichiza "Monosan"? Imiyalelo yokusebenzisa ibonisa ukuba ichiza a vasodilator peripheral, nto leyo yenza becala ezityeni lwemithambo.

Le medicament uyakwazi ukukhuthaza imveliso nemithambo endothelium endothelial iphumle into ezifana nitrogen oxide. Ngenxa yeziphumo enjalo ukusebenza enyibilikayo guanylate cyclase (transcriptase intracellular) ukuba ngokwaso kwandisa umxolelanisi vasodilating - elibujikele guanosine monophosphate.

Emva ezithatha ichiza ngaphakathi iiseli kunciphisa imfuno ioksijini engabalulekanga. Oku kungenxa ukuhla yokusebenza nasemva ukulayisha.

Kwakhona, iingcaphephe ababhalisele imithi isiphumo koronarorasshiryayuschee ngokukhawuleza.

imiphumela iziyobisi

Yintoni enye chiza iipropati "Monosan"? Ukusetyenziswa kweli chiza kunganciphisa igazi ukugeleza intendelezo ekunene, leyo kunciphisa kakhulu uxinzelelo kwi kwegazi yemiphunga nezengekho kunciphisa ubungqongqo iimpawu nokudumba yemiphunga nezengekho ezimbi.

Kufuneka kuqatshelwe ukuba phantsi kweempembelelo "Monosana" kwiindawo kunye kwegazi kukho nokunikezelwa yokumpompoza kwegazi coronary

Kwisiqalo beziyobisi kubantu angina kunye nesifo sentliziyo kobuchopho, kwandisa kakhulu ukumelana nawuphi na umsebenzi emzimbeni. Ukongeza, i-arhente mba ekwaziyo yandisa TX parameters Thrombocyte yokuqaphela kwaye zinqanda zegazi udibaniso.

iipropati pharmacokinetic

Apho ako, zathunyelwa futhi umzimba neziyobisi "Monosan"? Imiyalelo lithi isicelo ukuba isenzo ukwimo kweziyobisi kunokuba ngokukhawuleza ngokupheleleyo etsalwe lokugaya. Emva kokufumana amacwecwe isiphumo antianginal yabonwa emva malunga nemizuzu engama-30-45 kunye igcinwe kangangeeyure ezili-10.

Ngokutsho iingcali, iziyobisi "Monosan" lubafumana olude eliphezulu bioavailability (malunga 99-100%). Oku kungenxa yokungabikho lokupasa lokuqala ichiza ngokusebenzisa inkqubo hepatic.

Isiqingatha wobomi ichiza imizuzu engama-60. Uyondelelwano lwee- kweziyobisi egazini iyahluka kancinci, kuxhomekeka kuloo mntu.

Yokucolwa amachiza into esebenzayo esibindini. Ngenxa yokuba iinkqubo pathways kwakheka inamacandelo amathathu: glucuronide isosorbide ezimbini isosorbide--mononitrate 5.

nesiqingatha sexesha-ubomi iiyure 4-5. Xa oku 2.2% salawo ngokusebenzisa inkqubo kwezintso kunye 97,8% - njengoko metabolites glucuronic.

Ubungqina obubonakalayo buxela

Kuphantsi kwaziphi iimeko sabelwe "Monosan"? Ukusetyenziswa kwale imithi sisebenzayo kwezi meko zilandelayo:

• lwegazi yemiphunga, intliziyo pulmonary;
• iintlobo ezingapheliyo ukwehluleka kwentliziyo congestive;
• uthintelo stenokardicheskie of uxhuzula kubantu abanesifo kwemithambo.

Izimo

Kuphantsi kwaziphi iimeko ayikwazi ingasetyenziswa "Monosan"? Analogs kwaye kuthetha wathi ngokwayo Akuvunyelwe ukuba xa:

• ekuweni yegazi;
• nematha;
• lwemithambo hypovolemia kunye hypotension;
• tamponade intliziyo ;
• washiya ukusilela ventricular kunye indices ophantsi uxinzelelo lwegazi ukuzala;
• nokudumba pulmonary buthi;
• Isigaba nokoyika iposi engabalulekanga (kunye hypotension ngokukhawuleza);
• ifomu-ukuvalwa glaucoma;
• lwebele;
• izifo ukuba bawaphikise ukunyuka xi intracranial;
• hypersensitivity ngabanye;
• ebantwaneni kunye abafikisayo (ukuya kwiminyaka uninzi).

Kufuneka kuqatshelwe ukuba iingxelo kuthetha kukho Izimo isalamane. Le meko zilandelayo kusebenza kubo:

• stenosis mitral ;
• pericarditis constrictive;
• ebudaleni;
• izifo nemithambo ummiselo intolerance;
• inkqubo insufficiency sezintso;
• cardiomyopathy hypertrophic;
• hyperthyroidism;
• ukusilela hepatic ;
• stenosis aortic;
• igazi kakhulu ngaphakathi.

Drug "Monosan": imiyalelo yokusebenzisa

Inn (International Nonproprietary Igama) le iyeza iyalila "isosorbide mononitrate." Eli chiza ilawulwa ngomlomo kuphela. Ngokutsho imiyalelo, kufuneka uginye lonke wabahlamba phantsi ngamanzi.

Iipilisi kufuneka ubeke kwagqirha. Ngelo xesha linye ubophelelekile ukuba ukuhlola nobungozi besi sifo zokuziswa isiguli sakhe.

"Monosanom" Unyango uqala ukwamkelwa kuthetha 10-20 mg amaxesha 1-3 ngosuku. Iintsuku 3-4 ulungisa unyango kufuneka zenziwe Umthamo irejimeni. Ukuba kuyimfuneko, isixa kweziyobisi landile ukuya 20-40 mg kunye nokuthatha kabini ngosuku.

iimpawu libanda

Ziintoni iimpawu libanda, kungenzeka xa isigulane ofumana amayeza engalunganga "Monosan"? Imiyalelo yokusebenzisa zibonisa ezi mpawu zilandelayo: ukuwa, niphele, urhudo syndrome, isiyezi, hyperpnoea, anozizi eluswini, iimveku, dyspnea, tachycardia reflex imvelaphi, intloko ebuhlungu, eDayalayo, silale, ubuthathaka, ukwanda koxinzelelo intracranial, ukuphazamiseka ezibonwayo, ukuxhuzula, ukukhubazeka, isicaphucaphu, angabikho zingqondweni, ukubila, ukugabha.

Ekunyangeni iimeko ezifana zisetyenziselwa lokuhanahanisa lavage esiswini kwaye ukumisela enterosorbiruyuschee ithetha.

imiphumela emibi

Ngaba ezibi asabela iziyobisi "Monosan"? Imiyalelo yokusebenzisa (analogs of medicament ziboniswa ngezantsi), umisela ukuba ichiza enjalo kunokubangela ukuvela nobuninzi icala elingenzi nto-. Sikwathetha ezinye zazo:

• ukuphalaza;
• evuthayo imvakalelo elwimini;
• umlomo owomileyo;
• isicaphucaphu;
• komzimba;
• tachycardia;
• ikhanda nitrate;
• ukuthoba kwesikhumba ;
• nesiyezi;
• ukuncipha ko- wegazi;
• stenokardicheskie qho sokuwa;
• hypotension intolerance ;
• hypersomnia;
• zigule motor iimpendulo zengqondo;
• ukuqina;
• ukungaboni;
• ukumisela unyamezelo;
• irhashalala ethile;
• dermatitis exfoliative.

Analogs beziyobisi nexabiso layo

Nto leyo ethetha ukuba indawo amayeza «Monosan"? Analogue yale amayeza zifumaneka kuzo zonke ekhemisti. Phakathi ngempumelelo kakhulu kunokwenzeka ukuba ukwaba "Monocinque elawulwa", "Izoket", "Kardiket", "Efoksa", "Pektrol".

Njengoko ngexabiso ichiza, akukho phezulu kakhulu. Zuza kweziyobisi emizini Russian ungakwazi kuphela 100 (tablets 30).

baqinisekiswa

siye kuqwalaselwa chiza eninzi ingxelo entle. Izigulane athi iziphatha njenge arhente esebenzayo lwegazi yemiphunga nezengekho ezingapheliyo imilo ukusilela intliziyo. Nakuba kunjalo, kufanele kuqatshelwe ukuba zokufumana japan eliphezulu zonyango ezifana ichiza kufuneka zidityaniswe kunye nezinye iziyobisi. Ukuze wenze oku, qiniseka ukuba udibane kugqirha kokuya.

Nam ndingathanda ukuqaphela izigulane ukuba abaninzi akuthandileyo ixabiso ezingeniswe ichiza. Njengoko kukhankanyiwe ngasentla, amacwecwe 30 kuya kufuneka ukuba uhlawule imali engange Russian 100 kuphela.

Asikwazi ukuba malunga neziyobisi kusoloko kubashiya ingxelo embi. Kwiimeko ezininzi, ukuba zinxulunyaniswa ukuvela nobuninzi icala elingenzi nto-. Ngendlela, xa zithe zenzeka ngenxa yokufakwa kufuneka kushiywa kwaye endaweni ngendlela ekhuselekileyo. Yintoni kanye, uya kukwazi ukuxelela ugqirha onamava kuphela.