"Menopur": umyalelo, ixabiso, ncomo, iinkcazelo, umthamo

Esifuna iziyobisi "Menopur"? Imiyalelo iziyobisi, idosi yayo kunye nendlela yokusetyenziswa zichazwe kweli nqaku. Kuwo uya kufunda, yaye yintoni ubungqina kukho kweli chiza, ukuba uthe waba naziphi na iziphumo ebezingalindelekanga kunye Izimo ukuba izigulane ukuthetha ngayo, yintoni na ixabiso layo njalo njalo.

Ubume, uhlobo wokukhulula iziyobisi

wathengisa amayeza "Menopur" Ngayiphi indlela? Imiyalelo zokusetyenziswa ichiza iqulethe ulwazi ichiza esebenzayo uzayo ngohlobo lyophilizate, nto leyo senzelwe ulungiselela isisombululo for efakwa okanye inaliti ongama.

Ichiza eli preform nokuba limhlophe ngokwenza ngaphandle ivumba. Kwakhona incamathele kuyo sijike ezingenambala nengafihliyo.

Oko iqulethe iziyobisi "Menopur"? Imiyalelo ithi ukuba ubuncwane esebenzayo i follicle iziyobisi kunye luteinizing hormone. Kwakhona iquka excipients kwaye ngohlobo polysorbate 20, monohydrate lactose, sodium hayidroksayidi kunye zehydrochloric acid.

Isinyibilikisi sisisombululo of sodium chloride (isotonic).

imveliso ukupakisha

Amalungiselelo ekhoyo ukuthengiswa nengqayi ye ml-2. Kunye ke uyahamba isinyibilikisi (1 ml ampoule kweziyobisi equlethe). Xa elinye ibhokisi inokuba 5 okanye 10 iiseti.

Isenzo amayeza ye ichiza

Yintoni na ichiza "Menopur"? Imiyalelo yokusebenzisa licebisa ukuba eli chiza yindlela ephezulu ntumbuluko gonadotropin (ngxaki). Lingcwaba lomfo menotoropinov iqela kwaye iqulathe FSH kunye LH xa om-1 ukuya 1. medicament olulungiswe umchamo yabafazi postmenopausal.

Ngelo sex wamhle, oku kuthetha ukuvuselela endometrial ayanda, nokwanda kunye nokukhula zoboya ovarian kwaye ibangela ukwanda kwinqanaba estrogen egazini.

Njengoko kubantu besini ngokomelela, eli chiza kwandisa uyazikhomba testosterone. Ngaphezu koko, uyayivuselela spermatogenesis nge inyathelo iiseli tubular (imbewu).

Le pharmacokinetics wemveliso amayeza

iziyobisi "Menopur" sebenzi elingakanani? Guide ithi ukuba xi ubuninzi FSH egazini kuphunyelelwa emva malunga 7-24 kweeyure alandelayo ulawulo intramuscular. Emva koko umthamo wayo ngokuthe kunciphisa. Isiqingatha-ubomi iiyure 5-12 menotropinov.

Ubungqina obubonakalayo buxela ukuba ukusebenzisa amayeza

Imiyalelo ukuba ichiza "Menopur" ithi ukuba inokusetyenziswa kuphela intle, kodwa abameli oyindoda womelele.

Ngoko ke, cinga imbonakaliso zokusetyenziswa kukhulelwa asetyenziswa ngabasetyhini:

• ngokuba ekuzaleni (abancedisayo) nokuqalisa ekukhawulweni (ngamanye amazwi, ukuba ukukhuthaza ukukhula follicular);
• ngokuba unyango ukungachumi apho kungenxa hypothalamic-yebhinqa ukuphazamiseka (ngokuba inkanuko ukukhula follicle kuqala lubalaseleyo).

Kuba yintoni iinjongo ezimiselwe amadoda amayeza "Menopur"? Imiyalelo, impendulo, izicelo ziya thaca ngezantsi. Ngokubhekiselele ubungqina, abarhanelwa ziquka oku kulandelayo:

• ukukhuthaza spermatogenesis (kucetyiswa ukuba zidityaniswe kunye namachiza zabantu chorionic gonadotropin).

Nokuba kukho Izimo kwi ichiza?

Xa ungakwazi ukwabela ichiza "Menopur" (lyophilisate)? Imiyalelo yokusebenzisa ibandakanya Izimo zilandelayo:

• hypothalamic-yebhinqa indawo ithumba;
• Uphuhliso okungaqhelekanga of zokuzala, kwaye ubukho fibroids zesibeleko, nto leyo engahambelaniyo kunye nokukhulelwa;
• isifo amadlala adrenal kwaye ingaba lengqula;
• hyperprolactinemia;
• yesinye ovarian (elimandundu), kukuvela cysts (kulo mzekelo, ukuba isifo sinxulumana polycystic yamaqanda syndrome);
• umhlaza ovarian, zesibeleko okanye namadlala mammary;
• ukopha kusisi of imvelaphi engaziwayo;
• ukusilela ovarian Primary;
• nokukhulelwa;
• Umhlaza nobubovu yesinye, kwakunye nezinye yamathumba (androgenozavisimye) abameli wesini womelele;
• zisanyisa;
• ubuntununtunu (ukwanda) ukuba menotropinam kunye namayeza eziqulathe LH okanye FSH.

Ichiza "Menopur": imiyalelo, abstract

Inkcazelo ichiza sele uchazwe apha ngasentla. Ngokumalunga kweli candelo nqaku, ngoko ke siza kukuxelela ngayiphi idosi kufuneka ingqalelo ichiza.

Ukulungiselela iphethwe intramuscularly. Isisombululo injectable ukulungele ngaphambi nje ukusetyenziswa ngokusebenzisa kuphela esele ifakiwe nekhithi.

Xa kunjalo, ukuba ugqirha akazange abhalwe ngaphandle laphathwa ngendlela eyahlukileyo, kucetyiswa ukuba balandele ngqo le nkqubo ilandelayo.

abafazi

Kuba unyango ukungachumi apho kungenxa yobukho iingxaki kummandla hypothalamic-yebhinqa ukukhuthaza ukukhula lisalawula follicle komthamo wokuqala iyeza imiselwe ngamnye. Imali ngokupheleleyo iziyobisi kunye nexesha unyango, umnyulwa ngokusekelwe US ovarian, iimbono zethu unyango kunye nokumisela umgangatho estrogen. Hi ndlela leyi, ixabiso lokugqibela ugwetywa nokuvuthwa le follicle.

Ngoko ukusebenzisa njani na ichiza "Menopur"? Nomthamo kunye umthamo wamayeza lusoloko elinikiweyo imiyalelo apha. Imali yokuqala ichiza inokuba 75-150 IU (igutyana okanye 1-2 ngosuku).

Ukuba akukho mpendulo ovarian, ithetha umthamo ebegqwese ukwanda de follicular ukukhula kunye nokwanda amanqanaba estrogen. Le iidosi zishiywe zingatshintshanga de kube mzuzu xa xi igazi yokugqibela ifikelela amaxabiso preovulatory. Ngenxa yokwanda kakhulu amanqanaba estrogen ekuqaleni yashukunyiswa kuthetha kuyanqweneleka ukunciphisa izinga.

Emva kokuba naliti yokugqibela emva kweentsuku 2 kanye ilawulwa 5-10 amawaka. IU hCG. Ngaba ngenjongo yokuba ovulation induction.

abantu

ukuba alale nyi ukusebenzisa njani na ichiza "Menopur"? Umyalelo uthi ukukhuthaza spermatogenesis emadodeni kufuneka ufake amawaka 1-3. Kathathu ngeveki IU hCG. Yenza kwi kuqheleke kumanqanaba testosterone. Emva koko, ngokuba iinyanga eziliqela, kathathu ngeveki amayeza yayisalawulwa 75-150 IU (okanye iibhotile 1-2).

imiphumela emibi yokusebenzisa yasendle ichiza

Ngoku siyazi indlela amayeza kakhulu kufuneka lusekelwe "Menopur". Umyalelo, izigxeko-ncomo isicelo zithiwe thaca kweli nqaku. Noko ke, siphawula ukuba eli chiza kunokubangela ukubonakala inani yeziphumo ebezingalindelekanga.

• inkqubo yonyango: ukwanda (elibukhali) estrogen zinomgutyulo kwi umchamo, mastalgia, ukuyilwa cysts ovarian, ukukhula abangaxhalabisiyo kakhulu ovarian, gynecomastia (abameli besini eyomeleleyo).
• wokugaya: ukugabha, iintlungu abanabantwana, isicaphucaphu.
• reactions Local: bomvu, ukudumba kunye abafuna kwi indlela inaliti.
• Umzimba: irhashalala, ifiva, arthralgia, ukwakheka igciwane, leyo kunciphisa ukusebenza yonyango.
• Okunye: oliguria, ukutyeba, wegazi, ukukhulelwa ezininzi.

Kufuneka kuqatshelwe ukuba ukusetyenziswa kweziyobisi phantsi ingqalelo kungabangela ovarian hyperstimulation syndrome. Ngu iimpawu ezisaqalayo nokuphambuka okunjalo ziquka intlungu (ichazwe) esiswini, ukugabha, ascites, ukutyeba, isicaphucaphu, hypovolemia, electrolyte ukungalingani, hydrothorax, ukwandisa inani iiseli ezibomvu, hemoperitoneum kunye thromboembolism.

isikhokelo ngqo malunga nokusetyenziswa kwemali

Into ekufuneka uyazi phambi kokuba ngokusebenzisa ichiza "Menopur"? Qaphela, chaza ingxelo ukuba phambi zolawulo medicament ukuba isigulane kufuneka ubambe i unyango olufanelekileyo (ukuba insufficiency adrenal, hypothyroidism ezihamba, ummandla ithumba hypothalamic-yebhinqa, hyperprolactinaemia).

Phambi kokuqala unyango ubudlolo kufuneka ukuvavanya imeko zamaqanda. Ukuze wenze oku, yisa ultrasound kwaye ahlole umgangatho estradiol egazini. Ukutyhubela ezi zifundo kufuneka luphunyezwe ngomhla okanye yonke imihla.

Nceda uqaphele ukuba ukusetyenziswa kumxholo hMG yindlela yokuphuhlisa hyperstimulation ovarian. Njengomgaqo, kuyacaca ngokwezonyango kuphela emva ulawulo ichiza ngenjongo ovulation kwaye wabonakaliswa ekwimo ukuyilwa cysts ezinkulu. Kwiimeko ezinjalo, izigulane kufuneka hydrothorax, ascites, syndrome thromboembolic kunye hypotension.

Xa iimpawu kuqala unyango ngamachiza hyperstimulation ovarian kufuneka ngoko nangoko ayekiswe.

Xa agents unyango hMG zidla ukusekwa ukhulelwe.

Abameli besini eyomeleleyo kunye kwinqanaba eliphezulu FSH egazini ichiza nokungaphumeleli kwawo.

Yintoni na iindleko ichiza?

Yimalini sisiyobisi "Menopur"? Guide ixabiso le sixhobo zithiwe thaca kweli nqaku. Indleko yale ichiza phezulu kakhulu. 1 igutyana amayeza kuya kufuneka ukuba uhlawule malunga 1000-1400 engange Russian. Ukuqwalasela indlela avareji unyango na iintsuku 5-10, uthomalaliso ibiza isigulane ibiza kakhulu.

Reviews imithi

Kukho isixa esikhulu ingxelo entle medicament "Menopur". Ngokutsho kwabo, ichiza waba kakuhle kunyanga nenzalo, amaxesha amaninzi ukwandisa amathuba okuba ukukhulelwa. Phela, inani elikhulu lezigulane emva basisebenzise esi sixhobo yenziwe ukhulelwe.

Le ethile kuphela ichiza ingqalelo iindleko zalo. izigulane ezininzi abakwazi ukufikelela ichiza enjalo. Nangona usokhemisi bathi ixabiso eli chiza sifanelekile ngokupheleleyo. Enyanisweni, emva ukusetyenziswa kwayo efanelekileyo ithuba enkulu elide-elindelwe kwesisu kwaye, ngenxa yoko, ukuzalwa kudala lilindelwe umntwana. Ngoko ke, uninzi izibini eziselula abangenako ukukhawula umntwana ngaphandle kwamathandabuzo ufumane esi sibonelelo.