Izizathu, Pathogenesis kunye iimpawu sifo

Kwelinye iqela kwezifo samathambo ziquka ekuthiwa-microcrystalline okanye samathambo metabolic. Enye yezi sifo samathambo, iimpawu ezibonisa yazo esele eyaziwa ukususela noHippocrates. Esi sifo kwenzeka ngenxa ukutya kakuhle of uric acid kwisiqulatho salo ophezulu egazini, kwakunye nokufumba zophendlo lwezifo ziikristale (urate) apha emzimbeni. Ngoko iimpawu sifo ngokwezonyango kubonakale isenzeko samathambo ebukhali, kwaye ukuyilwa tophi, iindawo ezithile gouty.

AmaGrike wamnika igama sifo. Le yokuqala eyaziwayo ukuza kuthi ga ngoku, kukho inkcazelo sifo wanika ugqirha Greek Saranus. Esi sifo wabandezeleka Macedonian, Newton kunye nezinye ezaziwayo-kakuhle amanani amaninzi embalini.

Inani labantu abazifumana iimpawu sifo minyaka yonke kwandisa. Kunoko, loo nto ibangelwa ekuphuculeni umgangatho wobomi kunye namandla. Akumangalisi ukuba esi sifo ukwabizwa ngokuba 'sifo basebukhosini. "

Ingxaki yale sifo isigulo late, ngokufuthi sele kwinqanaba ezingapheliyo, xa inkqubo sifo nje amalunga ababandakanyekayo.

Iimpawu zokuqala sifo badla ukuqala ukuphazamisa amadoda eliqina. Kodwa sifo kakhulu "sihlaziyekile" mva nje. Izakufunyanwa ezingamashumi amathathu abantu abatsha. Kuba inkoliso yabo efuna ukuhlasela uncedo sifo luqala yimbonakalo intlungu ukudumba lokuqala (enkulu) toe. Olu luguqulelo zakudala. Le ezinye ziphawulwe iintlungu kwezinye amalungu yonyawo, kuquka amalungu ezinkulu imilenze.

Ukuze siqonde Pathogenesis esi sifo, kufuneka ukuba bayiqonde ukutya eqhelekileyo uric acid. Xa abantu, oko kubangelwa ukuqhekeka purines. Xa imithombo yethu ephilayo bokwakha loo asidi zabemi ukutya zoqhagamshelwano eziqulethe purines (inyama, imidumba, newayini ebomvu, intlanzi, njalo-njalo), iiseli Nucleoproteins. Idubule uric acid na imveliso ngokusebenzisa emathunjini zifunxe iintyatyambo isisu, kunye nomchamo (inxalenye yayo enkulu).

Ezibangela isifo

Yinto eyaziwayo ukuba kukho iimpawu sifo ngokuhlanganisa agqithisile uric acid emzimbeni kunye nokunciphisa zinomgutyulo yayo yokuchama. Ukwandisa ukwakheka asidi inokuba ngenxa kukutya kakhulu ukutya eziqulathe purines kunye ephakamileyo, kuyondelelaniswe engaphakathi purines emzimbeni.

Anikezele primary kunye hyperuricemia eziziisekondari. Igawuthi kusisiphumo lwalo lokuqala. Secondary ukwanda uric acid egazini idla ngenxa ukusilela kwezintso, ezigula ezininzi, iintlobo ezithile wegazi kunye anaemia, yaye sikubonisa kwisicelo ngamalungiselelo ezithile zonyango, umzekelo, womchamo.

Agqithisile acid egazini kukhokelela nokufumba yayo Amalungu nezihlunu. Xa uhlobo sodium urate ekufakwa kwi Bursa lingena singene kulwelo synovia. Urata ukungena kulo intlala, ebangela ukudumba kunye nomonakalo.

iimpawu sifo

Njengoko sele kutshiwo ngentla apha, a version zakudala sisifo elidityanelweyo nakubhontsi. Ngokwawo, agqithisile uric acid emzimbeni musa esingenakubangela naliphi na iimpawu, yaye isenza ingqalelo ngokoyiswa eli joint ethile. Rhoqo ukuqhambuka kubangelwa kukuzingxala, emzimbeni, emphefumlweni okanye usuleleko. Amaxesha amaninzi kuhlasela samathambo kwenzeka ngokuchasene nemvelaphi epheleleyo kakuhle-ntle, nangona ngamanye amaxesha zimakishwe iimpawu-uhlobo ezifana utshintsho rhoqo isimo, ukuba nochuku ngokugqithiseleyo, njl

Ngokuqhelekileyo ubuhlungu kuvela ebusuku kunye ngesiquphe. I buhlungu kakhulu kangangokuba akunakwenzeka ukuba bachukumise entlanganweni. Ngelo xesha kukho ukudumba kwaye bomvu. Emva kweentsuku omnye okanye emibini, iintlungu uya kude. Eyona uphawu zeentlungu samathambo na ekuqaleni ngesiquphe nokuziphatha kunye kutshatyalaliswa ngequbuliso. Ukuba amalungu ezinkulu ayachaphazeleka, umfanekiso yinto kusikhumbuza phlegmon. Amalungu ukuze kwakheke tophi. Bona amaqhuma zilahlwe phantsi kwesikhumba okanye amalungu (iidipozithi urate). Amanqanaba igazi ephakamileyo uric acid.

unyango

In acute ukuhlasela colchicine esetyenzisiweyo, anti-ukudumba, iziyobisi iintlungu (NSAIDs). Kunyanzelekile ukuba lokudla ngaphandle mgangathweni.Ukutya byproducts inyama, utywala.

Inyathelo lesibini ukuqeshwa iziyobisi ukunciphisa imveliso umzimba ngayo uric acid. Ngaloo ichiza allopurinol okanye analogs yayo. Eli chiza isetyenziselwa unyango rhoqo ixesha elide ..