Inkcazelo kunye Umsebenzisi "Melitora"

Kweli hlabathi lanamhlanje Abantu abaninzi baqhelene nale meko, ezifana nokungonwabi. Olu hlobo disorder ngengqondo, esibonakala ngesimo udandathekile, ukulahleka ubuchule ukonwabela, kwakunye sasiphikisana yokucinga (kwicala negative) kwaye motor yokudodobala.

Ngexesha ukuxinezeleka ebantwini kakhulu kuncitshiswa ukuzithemba, kwaye kukho ilahleko umdla kwimisebenzi yesiqhelo kunye nobomi jikelele. Kwezinye iimeko, isigulane uqalisa kakubi utywala okanye nayiphi na into. Ukongezelela, abantu baye ekudala exinezelekile, ukuzibulala. Ngoko ke aphume kwimeko enjalo kufuneka kwenziwe. Ukuze wenze oku, nceda qhagamshelana i nogqirha onamava.

Inani elikhulu iinkampani ezixuba amayeza ngokukodwa xa kusenziwa ekuthiwa yokunciphisa. Le mithi psychotropic ukuba abe negalelo elingqalileyo kwinqanaba neurotransmitters, kuquka dopamine kunye serotonin. Xa umntu odakumbileyo izixhobo ezifana uzixolise, ukunciphisa ukudinwa, lulekani ukudakumba, ukuphelisa unxunguphalo, namdla emoyeni.

Enye siyobisi ethandwa bucala i "Melitor". Imiyalelo yokusebenzisa, ukubuyekeza kwimveliso ezingamayeza thaca ngezantsi.

Inkcazelo, ifomu ukukhululwa, ukwakheka, ukupakishwa

Le medicament "Melitor", imiyalelo yokusetyenziswa leyo okulungiswe ibhokisi, ifumaneka azipilisi. Ukuba sibe side naorenji-yellow umbala. Kwakhona, ichiza igutyungelwe cover ifilimu. Kwelinye icala tablet ngumvelisi logo yoshicilelo.

Xa intengiso iipilisi kufika imiqulu blister lamaqhosha-14.

Nayiphi na into iqulethe iyeza "Melitor"? Imiyalelo Sebenzisa ithi zithako yalo, agomelatine izenzo. Kwakhona amacwecwe zibandakanya izinto ezongezelelweyo ngohlobo stearic acid, monohydrate lactose, povidone, umbona starch, sodium glycolate (uhlobo A) starch, dust anhydrous colloidal nezinki stearate.

Pharmacology

"Melitor" Amacwecwe (umyalelo yokusebenza ezichazwe ngezantsi) zezi arhente yeQela ochaphazela luvo nangempumelelo esizibonakalisa kwiintlobo ezahlukeneyo ndidandatheka. Ukongeza, le ichiza iphutha kunye de-ungqamaniso zesingqisho lomzimba, unxunguphalo nokuphazamiseka.

I engekho mthethweni esebenzayo kugqalwa agonist MT2- melatonergic kunye MT1-receptor ochasene ne-HT2C 5 receptor. Esi sixhobo Akukho noFaro ngenxa cholinergic, histamine, dopaminergic, beta- Alpha-adrenergic receptors kunye benzodiazepine, yaye akatshintshi iqondo zife monoamines. Eli chiza ulinganisa izingqisho lomzimba, oko normalizes isakhiwo bubuthongo, lukwakhuthaza imveliso melatonin kwaye ilungiselela nokulala.

Xa usebenzisa ichiza ukunyanga abantu abanengxaki ukudakumba, kukho kungoluka bubuthongo kade-ngumtshangatshangiso. Ke ukuba REM, oko akayi naluphi na utshintsho.

Kufuneka kuqatshelwe kanjalo ukuba esi sixhobo ikwazi zivuse kokukhutshwa noradrenaline kunye dopamine kwi ngumonzakalo nomhlehlo ngokungqalileyo ebuchotsheni. Kulo mzekelo, agomelatine ayitshintshi inqanaba serotonin extracellular.

iimpawu ichiza

Ziziphi iinkalo ezendeleyo ichiza "Melitor 'na? Imiyalelo, ukubuyekeza bathi kukuba lamavolontiye asempilweni akazange abe nefuthe elibi inkumbulo, ubunzima bomzimba, ukukwazi ingqalelo, uxinzelelo lwegazi, izinga lentliziyo kunye iintshukumo zesondo. Ukongeza, agomelatine akuthethi ukuba likhoboka lazo. Emva Nhoza unyango iye yaphuhliswa.

kinetics

Yintoni iimpawu kwikinetiki na amayeza phambi kwethu? Oko ikuthethayo manual? "Melitor" ako kakuhle iphecana zesisu. bioavailability yayo epheleleyo yi-3%. Kodwa ngokuxhomekeke iimpawu umntu okunzulu ezibalulekileyo. Hi xikombiso, le bioavailability sex wamhle beziyobisi ingaphezulu ebantwini. Ngaphezu koko, ukutshaya kunciphisa umyinge wathi, kunye nokusetyenziswa zokucwangcisa zomlomo, phezu koko, kwandisa.

I kwincopho abasuka isithako esebenzayo egazini waphawula emva kwemizuzu 70-100 emva ulawulo ngomlomo. Kuba iqondo eliphezulu malunga bucala kwiiproteni plasma (95%).

Nethe kuthetha kwenzeka esibindini ukuba iikhompawundi engasebenziyo. izintso drug iboniswe (malunga nama-80%) iiyure ezimbini.

ubungqina

Kutheni sifuna unyango 'Melitor "? Guide ingxelo ukuba ichiza ilungiselelwe ukuba ukunyanga abantu abane ngeziqendu depressive.

Izimo

ndifanele liqeshe Xa yeQela phambi kwethu? Oko ikuthethayo manual? "Melitor" into contraindicated ku:

• hypersensitivity ngamnye ukuba ichiza;
• elactase okubangelwa;
• umsebenzi isibindi kakhulu;
• malabsorption glucose / galactose;
• e ebudaleni;
• nobandlululo galactose naso;
• nokukhulelwa;
• njengomntu;
• ibele.

Ukongeza, loo nto ithetha emiselweyo isilumkiso xa izigulane hypomania okanye mania kwimbali, waphula umthetho izintso, xa butywala (kulo mzekelo, ukuba umntu afumane unyango amayeza hepatotoxic).

umyalelo

"Melitor" ilungiselelwe yolawulo ngomlomo. Iipilisi angawokubhuda yonke ngaphandle kukutyumza okanye ukuhlafuna. is he taken kungakhathaliseki ukuba ukutya. Ngophuhliso yeziphumo ebezingalindelekanga ezivela iphecana zesisu kunye namayeza enokusetyenziswa xa kutyiwa.

Le idosi yemihla ngemihla kufuneka zisetyenziswe kanye ngemini, ebusuku.

Ubude unyango kunye nedosi amayeza ugqirha imisela ngabanye baguquke.

Ngokuqhelekileyo omdala ukumisela ngomhla wama-25 mg kweziyobisi ngamnye ngosuku. Xa wavakalisa isiphumo zaneleyo zonyango emva kweeveki ezi-2 unyango idosi inyuswe ukuya kuma-50 mg ngosuku.

Abantu abafumana unyango olunjalo kufuneka bathi gqolo ekubekeni iliso umsebenzi esibindini.

kufuneka ungabi ngaphantsi kweenyanga ezintandathu ubude Course kwizigulane kunye nokudakumba.

imiphumela emibi

Kulungile ukuba sihambisane neziyobisi phambi kwethu? Yintoni le usixelela manual? "Melitor" kuphela kwezinye iimeko, ebangela uphuhliso yeziphumo ebezingalindelekanga. Kulo mzekelo, uninzi lwabantu ke emva kweeveki-2.

Ngoko ke, lo gama uthatha isixhobo zingenzeka kwizigulane:

• isicaphucaphu, gastralgia, isitulo kakuhle, ukwanda transaminase isibindi no;
• isiyezi, migraine, intloko ebuhlungu, ukungaboni, kuvukwe kakuhle kwaye imo yokucima, paresthesia, yokuzibulala, ixhala elimsulwa;
• irhashalala eluswini, izigxala, ukurhawuzelela, amaqhakuvana erythematous kunye nerhashalala;
• myalgia, asthenia, iqolo.

libanda, iziyobisi

Ziziphi iimpawu kwenzeka xa libanda, iipilisi 'Melitor "? Manual ithi ngeli xesha kwexesha iingxelo ezinjalo ezivela izigulane ziye ingxelo. Emva kokufumana ichiza ngeedosi eziphezulu eboniswe lavage esiswini kunye ehnterosorbentov otyiwa. Kwakhona unyango nomqondiso.

imithi

Le kinetics beziyobisi phantsi ingqalelo inokwahluka xa kudityaniswe neziyobisi umzimba cytochrome enzymatic CYP 2C9 / 19, kunye P450 1A2. Ngokukodwa, ayikhuthazwa tu into yokuba ukwabela eli chiza with "ciprofloxacin" yaye "fluvoxamine".

Njengoko for "propranolol", "enoxacin", "Grepafloksatsina", kufuneka zisetyenziswe ngononophelo kakhulu kwabo sele abafumana unyango "Melitorom".

Nutrition kunye nokukhulelwa

Ngaba ixesha lokumitha ukuba ichiza "Melitor"? Guide ingxelo ukuba esi sixhobo linokukwenziwa abafazi abakhulelweyo, kodwa kuphela ngenxa yezizathu zempilo. imifuniselo Animal wabonisa ukuba agomelatine aluchaphazeli kakubi kuphuhliso olungekazalwa. Nangona data ukhuseleko esi sixhobo xa abasetyhini abakhulelweyo akwanelanga.

Ukuba kufuneka ichiza ukuthatha ngexesha zisanyisa, kufuneka udibane nogqirha wakho kwaye isigqibo ekupheleni kwexesha lokuncancisa.

iingcebiso ezithile ukufumana amayeza

Into ekufuneka uyazi phambi kokuba uthathe amayeza "Melitor" (25 mg)? Imiyalelo, ukubuyekeza ingxelo ukuba esi sixhobo akukhuthazwa ukuba izigulane abalupheleyo.

Ngophuhliso iimpawu manic, unyango kufuneka uphazamiseke.

Kwezinye iimeko, ukuphucuka emva kokuthatha iipilisi abayenzi lonto kwiiveki zokuqala ezimbalwa. Ngoko ke, imeko yomguli kufuna esweni rhoqo. Kumanqanaba okuqala kuphuhliso recovery abanezicamango ukuzibulala nande.

Zonke izigulane abafumana "Melitor", qiniseka ukuba esweni umsebenzi esibindini. Xa imigangatho ephakamileyo transaminases kwiimvavanyo kwegazi kufuneka kuphindwa zingadlulanga iintsuku ezimbini. Ngokwandisa indices amaxesha 3 uthomalaliso wayeka.

Unyango ukuba kukho imfuneko yokwenza iziyobisi ngokuqaphela ukuba ogulayo imiba ingozi yokwenzakala kwesibindi, kuquka ukutyeba, isifo okunamafutha non-ezinxilisayo, kwakunye ngesifo sephepha utywala kakhulu, okanye ngaxeshanye ukufumana imali ezinempembelelo hepatotoxic.

Analogs neendleko

Ixabiso yeQela "Melitor" ngu 850 engange. Ukuba kuyimfuneko, ibe yindlela indawo iziyobisi ezifana "Lotosonik", "Azafen", "Neurol," "Adepress", "Tsetol", "Sevpram", "Zaloks", "Trittiko" kunye t. D.

baqinisekiswa

Ngoku uyazi iimpawu yeQela njenge "Melitor". Imiyalelo yokusebenzisa iyeza sele kuchaziwe ngentla.

Izigulane ezininzi zithi esi sixhobo ngempumelelo esizibonakalisa a ukudandatheka. Oku kushenxisa ukudakumba, kunciphisa silale kwaye ibuyisela a ompe ubomi. Nakuba kunjalo, kufanele kuqatshelwe ukuba amisele eli chiza kufuneka abe oqeqeshiweyo nonamava kuphela. Ukuba uya kukwazi ukubona ukuba idosi ekhuselekileyo amayeza kunye nobude unyango.

Kwakhona, yemfaneleko abathengi isixhobo ziquka okuba aphantsi ziziphumo ebezingalindelekanga, Izimo kunye imali encinane lula ezisetyenziswa (tablet zithatyathwe kanye ngosuku).

Njengokuba kubakho iingxaki, kuphela iindleko eziphezulu ichiza awanyange.