"IFN-Lipint": ncomo, uqeqesho, analogs, isicelo, ixabiso

Lithetha "IFN-Lipint" yi ichiza antiviral ukuba yenziwe ngokusekelwe interferon. Ukwakhiwa kwale kuqulunqo siquka womile amayeza alpha-2 yabantu interferon-beta. Ichiza, njengezinye iziyobisi, apho isakhiwo nayo iquka le compound ikhuthaza amajoni omzimba wakho lomntu. Ukusetyenziswa kwezi imithi ikhutshwa phandle izilonda ezahlukeneyo esosulelayo xa buthathaka impilo yakhe. Umzekelo, ngethuba immunotherapy, izifo zenkqubo yezemfundo.

"IFN-Lipint 'lisetyenziswa:

• Ekwenzeni ngexesha bhubhane yothintelo SARS.
• Kwimeko izifo lwenkqubo, ezifana atopic dermatitis, isifuba kunye like. D.
• In viral hepatitis B - zombini oyingozi futhi ezigulo ezondeleyo.

"IFN-EU Lipint" ifumaneka ifomu powder. Ukuze igutyana lifakiwe kwangoko phambi ukusebenzisa Yek okanye ikuphekwa iphekwe ngamanzi, yaye emva koko yonke ngamandla ezingenakuzanyazanyiswa. Ngokutsho imiyalelo, ichiza Kucetyiswa ukuba isiqingatha seyure phambi izidlo. Kodwa icebo lakhe isicelo ngokukodwa isigulane ngasinye, ugqirha unyanzelekile ukuba ukupeyinta iinkcukacha. Njengoko umthetho, ikhosi epheleleyo yonyango akukho nyanga ngaphezu kwesinye.

iintlobo yokukhululwa ezikhoyo, ixabiso

• Powder lyophilized 500,000 IU / ml (ngomlomo) - ixabiso 700 engange.
• Ukuze alungiselele lyophilized umgubo oluludaka 1.000.000 IU (ngomlomo) - ixabiso malunga 1000 engange.
• Ukuze alungiselele ukunqunyanyiswa i lyophilised umgubo 250.000 IU (ngomlomo) - malunga 410 engange ixabiso.

"IFN-Lipint": nabalingani

Eli chiza le analogue zilandelayo:

• "Infagel".
• "Viferon-mafutha".
• "Viferon".

Ubungqina obubonakalayo buxela

Lyophilized powder 1 yezigidi IU ne-250 000 IU ukwenzela ukusetyenziswa lwangaphakathi kucetyiswa kwezi meko zilandelayo:

• Treatment kunye nokuthintela izifo ezihlasela zosulele wentsholongwane egazini bokuphefumla nomkhuhlane.
• multiple.
• nee- kaThixo ezinxulumene ne-AIDS.
• Clasmocytoma.
• fungoides Mycosis.
• umhlaza sezintso.
• ezigula ezininzi.
• ifomu Transition granulocytic leukemia ezingapheliyo kunye myelofibrosis.
• thrombocytosis eziziprayimari nezizisekondari.
• Active hepatitis viral C.
• leukemia Myeloid ngendlela ezigulo ezondeleyo.
• iseli leukemia Xhonti.

Powder lyophilized 500,000 IU / ml "IFN-Lipint" njengoko amafutha esetyenziswa sisilonda esidumbileyoesingaphakathi inwebu wentsholongwane egazini yangaphakathi kunye integuments of eyendawo ezahlukeneyo.

Ifom etyalike kuqulunqo suppository isetyenziswa kunyango kunye izifo ezifana:

• Izifo ezisulelayo-yokukrala abantwana, kuquka iintsana ngaphambi kwexesha kuzalwa.
• Meningitis.
• Nokudumba.
• Umkhuhlane, SARS, kuquka kubunzima igciwane.
• Chlamydia, inyumoniya wentsholongwane amagciwane.
• usuleleko intrauterine - usuleleko enterovirus, usuleleko CMV, i-herpes, i-chlamydia, candidiasis, kuquka mycoplasmosis visceral.
• Viral kohlobo B, C, D abadala kunye nabantwana, kuquka zidityaniswe hemosorption kunye plasmapheresis hepatitis wentsholongwane egazini ezingapheliyo kunye zesibindi kwesibindi kunye nezinga enkulu yomsebenzi.

Njengoko i interferon-olungisa lithetha "IFN-Lipint" (ixabiso ezinikwe apha ngentla) isetyenziswa kwimeko zifo zilandelayo:

• usuleleko enzala (usulelo papillomavirus, mycoplasmosis, candidiasis kusisi nezolo, vaginosis ziibhakteriya, itrichomoniasisi, ureaplasmosis, vaginosis ziibhakteriya, CMV usuleleko, chlamydia).
• Phindaphinda okanye primary usulelo isifo kunye nesikhumba.
• Umkhuhlane kunye nezinye izifo zemiphunga etsolo kunye zokudala, kubandakanywa iingxaki abadala igciwane.

Izimo

Drug "IFN-Lipint" (ixabiso kuxhomekeke kwifom release) unawo Izimo zilandelayo:

• umsebenzi kakuhle intso, isibindi okanye kwegazi.
• Hypersensitivity.
• kohlobo kwizigulane abafumana nje kokuba unyango immunosuppressive (ngaphandle elifutshane pre-unyango kunye steroid).
• iposi engabalulekanga.
• kohlobo kwabangela decompensated isibindi ukuqina.
• isifo sentliziyo ezimandundu (kuquka imbali).
• Sokuwa okanye ezinye ukuphazamiseka kwenkqubo luvo central.

Ukongezelela, "IFN-Lipint" (. Izimvo yokulungiselela, bona ngezantsi), inazo umda nokusetyenziswa:

• uvakalelo oluphezulu ukuya engenayo kwamalungu zeziyobisi.
• Ibele.
• Ukukhulelwa.

imiphumela emibi

Lyophilized olungumgubo yomlomo 1.000.000 IU ne-250 000 IU "IFN-EU Lipint" (ixabiso ixhomekeke imilo yokhululo) unawo iziphumo ebezingalindelekanga kulandelayo:

• reactions isikhumba komzimba (umz, ukurhawuzelela kunye ezindlwini).
• ukuphazamiseka kokulala.
• Luvalo.
• ukwazi kwamehlo.
• Ubuthongo.
• Depression.
• retinopathy kobuchopho.
• ukuphazamiseka Visual.
• Nesiyezi.
• Kwesibindi.
• umsebenzi kwesibindi ezingahambi.
• Heartburn.
• peristalsis Ukwandiswa.
• Flatulence.
• Nokuqunjelwa.
• iintlungu esiswini.
• Ukugodola kunye nomkhuhlane
• Norhudo.
• umzimba.
• umlomo owomileyo.
• Tshintsha ecocekile.
• Ukugabha kunye isicaphucaphu.
• Ukubila.
• Intlungu kwamalunga.
• Intloko ebuhlungu okanye ubuhlungu kwezihlunu.
• imnyama.
• Silale.

"IFN-Lipint" lyophilized olungumgubo abantwana 500 000 IU / ml:

• Ioli - iziphumo ebezingalindelekanga sele kuthethiwe.
• Suppositories - enqabile wabonakalaliswa uxabane (umz, urhawuzelelwa okanye nerhashalala).

intsebenziswano

Interferon alpha kunciphisa umsebenzi cytochrome P-450, nto leyo echaphazela nethe of warfarin, propranolol, diazepam, theophylline, chimes, phenytoin cimetidine kunye amanye amachiza cytotoxic. Kwaye kungandisa cardiotoxicity, neurotoxicity okanye iziphumo myelotoxic iziyobisi, ziye wawuqalayo ukuthatha ngaxeshanye okanye ngaphambili.

Ukongeza, imfuneko ukunqanda ulawulo ezihamba "IFN-EU Lipint" (ixabiso eboniswe ngasentla) kunye iziyobisi negalelo ingcinezelo kwenkqubo luvo, kwakunye namachiza immunosuppressive (kuquka iifomu parenteral nangomlomo of corticosteroids).

Akuvunyelwe ngokungqongqo ngexesha unyango ukuba athathe utywala.

umthamo kunokwenzeka

Ichiza kuthathwa isiqingatha seyure phambi kokuba nokudla ukutya. Kuba kuthintelo SARS kunye neAvian - 1 philisi (500 000 IU) ngosuku ngexesha nyanga, amaxesha-2 ngeveki. Xa unyango lwe-SARS kunye neAvian - 1 philisi (500 000 IU) yonke imihla iintsuku ezi-5, amaxesha 2 ngemini. Xa igwinya nzima ukuba ukuvula ngenyameko philisi uthabathe imixholo omncinci amanzi.

Umthamo kunye noLawulo

Le medicament iphethwe ngomlomo. Ngaphambi kokuba isicelo ngqo okubhalwe igutyana adityaniswe okubandayo ikuphekwa iphekwe okanye iziqholo amanzi (1.2 ml). Ngenxa yoko, malunga 1-5 imizuzu, kufuneka avele behlunguzela enobunzima eyohlobo olulodwa.

1. Kwimeko ahlekise hepatitis medicament sithathwa imizuzu engama-30 phambi kokuba yokuselelwa ukutya yi-scheme kulandelayo:

• Abantwana ukusuka 3 ukuya kwiminyaka esi-7 - ichiza kuthathwa iintsuku ezili-10, 1 ixesha ngosuku 500 000 IU. Emva izifundo kwemichiza lovavanyo igazi "IFN-Lipint" abantwana (ixabiso kuxhomekeke kwifom release) asetyenziselwa ixesha elide - phambi kokuba kuqala recovery ngokupheleleyo clinical.
• Abantwana abadala ngaphezu kweminyaka esi-7 ubudala kunye nabantu abadala - kwiintsuku ezili-10 ka-2 ngemini, izigidi-1 IU.

2. Kwimeko kohlobo B iifom replicative (esebenzayo okanye engasebenziyo), kubandakanywa kohlobo B, ezinxulumene ne glomerulonephritis, ichiza kufuneka athathwe kwimizuzu engama-30 phambi kokuba ukutya, ngolu hlobo lulandelayo:

• Abantwana ukusuka kwiminyaka emi-3 ukuya kwesi-7 ubudala kufuneka silithathe eli amayeza iintsuku ezili-10, amaxesha 2 ngosuku 500 000 IU, uze emva koko - ukuba 1 xesha ngenyanga 1 ngosuku (ekukhethwa ukuba ebusuku) ngosuku, 500 000 IU.
• Abantwana abadala ngaphezu kweminyaka esi-7 ubudala kunye nabantu abadala - kwiintsuku ezili-10 ka-2 ngemini, izigidi-1 IU, ngoko 1 xesha ngenyanga 1 ngosuku (ebusuku) ngemini.

3. Kwimeko kwanonyango ethile, "IFN-Lipint" (izimvo ngezantsi) kufuneka lusebenziswe ngaphakathi kwimizuzu engama-30 emva kokuba esidlweni iiyure kusasa ngolu hlobo lulandelayo:

• Kwimeko abadala sombefu atopic - 10 iintsuku yonke imihla 500 000 IU. Ngoko, kwiintsuku ezingama-20 emva kolo suku 500,000 IU. Ubude zizonke iintsuku ezingama-30.
• Kwimeko rhinoconjunctivitis komzimba - iintsuku ezili-10 yonke imihla 500 000 IU.

4. Ukulungiselela injongo nokuthintela kunye nokunyanga izifo ezihlasela zosulele ngokuphefumla kunye nomkhuhlane le iyeza kuthathwa isiqingatha seyure phambi izidlo. "IFN-Lipint 'ukuba ukusetyenziswa myalelo kuqinisekisiwe, kufuneka usele ngolu hlobo lulandelayo:

• Xa unyango lwezifo yokuphefumla acute kunye neAvian - kwisithuba seentsuku ezi-3 imihla amaxesha 2 ngosuku 500 000 IU.
• Ngenjongo yokuthintela lwe Ari okanye umkhuhlane - kunye ngokuvela okugula ithathe amayeza nyanga 1 umphinda-2 ngeveki kwexesha ngeveki 1 ngosuku 500 000 IU.

libanda

Amatyala elingaphezu umthamo ichiza uyalandelwa. ukwanda Mhlawumbi kuphela ziziphumo ebezingalindelekanga ezinxulumene ne-dose. Libanda olunikiweyo unyango nomqondiso.

amagama afanayo

"Eberon Alpha P", "IFN-EU Lipint" abantwana "Realdiron", "ALFARON", "Layfferon", "Intron-A."

iarhente

Ichiza kufuneka zigcinwe apho abantwana abancinane, ekhuselweyo kwindawo elangeni. Ngoko lobushushu yokugcina mayingagqithi 8 ° C.

izincomo ezithile

Ichiza alunasiphumo kwi uyakwazi ukulawula ngoomatshini abayingozi kunye nezithuthi. Ukuba ngaba wehlelwa komzimba kufuneka bafune unyango ngoko nangoko.

njengoko kukhululwa

"IFN-Lipint" abantwana (iimbekiselo ngezantsi) uyakhululwa kuphela liyeza evela kugqirha.

iingcali Izimvo

Eli chiza ngaxeshanye iye anticancer kuphela umsebenzi antiviral, kodwa kwakhona ukukwazi ukubuyisela amajoni omzimba. ukusetyenziswa kwayo kabanzi kokuba ufumene unyango walo wentsholongwane egazini hepatitis B, njengezinye amachiza antiviral ngaphandle phambi kokuba wamiselwa, kunjalo, ngenxa yoko, ithemba ngakumbi ukusebenza antiviral. kwiintsuku ezi-5 emva kokuba isifo senyongo yena engasekho emiselweyo.

Ukongeza, eli chiza lisetyenziswa kwimeko meningoencephalitis wentsholongwane egazini, kodwa kuphela zokuqala iintsuku ezine sifo. Enye "IFN-Lipint" ngokubonakalayo kusetyenziselwa conjunctivitis wentsholongwane egazini kunye keratitis. umsebenzi Antitumor ikuvumela ukuba abele eli chiza kwezinye iintlobo ngeentlobo umhlaza, ingakumbi izifo egazini somhlaza. iziphumo ezigqwesileyo sele ifunyenwe kwi unyango lwe multiple.

Kwaqondwa ukuba iindidi ezithile izigulane kakuhle wabunyamezela ukusetyenziswa kweli chiza: kukho ukudinwa, ubuthathaka, ifiva, kuthibaza. Noko ke, nangona oku, ikhondo yonyango, kwiimeko ezininzi, kufuneka ukuba uqhubeke.

Ngamanye amaxesha uphathwa ukwehla okukhulu zegazi kunye leukocytes, nto leyo ifuna ulawulo analysis igazi imigqaliselo zonyango (malunga 2-3 amaxesha ebudeni ngeveki). Nangona iziphumo ebezingalindelekanga, njengoko umthetho, ukurhoxiswa ngokukhawuleza ichiza iyapheliswa, ukususela ukupheliswa ngesigqibo sayo kufuneka zithathwe kuphela oyingcali, umisele "IFN-EU Lipint". Oku kungenxa yokuba iinzuzo ezilindelekileyo mkhulu kangangokuba isigqibo ukutshitshisa imfuneko ukuba siqwalasele indlela kakhulu elungeleleneyo.

buhle

• Xa intliziyo yalo ichiza lophuhliso lwenzululwazi, leyo wawongwa Russian Prize Government.
• Xa kuthelekiswa nezinye iziyobisi, "IFN" kufuneka sithatyathwe ngomlomo (ngomlomo). Le nto ibaluleke kakhulu wezifo.
• interferon Liposomal ngogqibeleleyo ukuze uthintelo olungxamisekileyo ka-SARS kunye neAvian, xa kwakukho wadibana yintsholongwane, kodwa iimpawu zesi sifo azinazo okanye kulingana buqapheleke kuphela.
• Liposomes ukukhuthaza kwegazi ixesha elide kwi interferon egazini.
• "IFN" usebenza njenge inductor, oko kukuthi, igalelo kuphuhliso interferon yayo.

Amalungiselelo iquka interferon amayeza, nolwathi lwaphuhliswa yi zobunjineli yemfuza nqubo ku vitro. Ngamanye amazwi, eli chiza ayikho imveliso igazi yendalo kwaye alikwazi ezinokuqulathwa usuleleko enobungozi.

oyi

Njengoko ngaphambili kukhankanyiwe, ngethuba ukuthatha eli yeza ukunqanda udityaniso yalo immunosuppressants, kwakunye mayeza azinazo naziphi na iimpembelelo kwi-CNS. Kuyo yonke le khosi kubaluleke kakhulu ukuba esweni umsebenzi wesibindi egazini kwasekwa izinto. Ukuba ngandlel unciphise iimpawu ezifana nomkhuhlane (side effects), kukhethwa ngaxeshanye yokwamkela la malungiselelo abele paracetamol.