Ichiza "Concor Kor": ezibonisa ukusetyenziswa, nabalingani real

Izifo sentliziyo ngoku phantse kwindawo yokuqala izinga lokusweleka ehlabathini. Yaye le ngxaki ukuze abaselula qho ngonyaka. Ukuba uthe ngaphambili malunga iposi engabalulekanga, kwaba umbuzo malunga eneminyaka engama ubuncinane 45-50, namhlanje esi sifo lokuqhankqalaza, kunye nonyaka-30 ubudala.

Modern Pharmacy enobunzima imithi yokulwa iingxaki "kwentliziyo" akumanqanaba ezahlukeneyo zophuhliso ezi zifo. Elinye iqela la machiza blocker beta. Umgaqo esebenza ngayo le mali ukuba ukuvala receptors beta-adrenergic entliziyweni. Le nokulandelelana ukuhla kwireyithi intliziyo, nto leyo ekhokelela ukuthoba uxinzelelo lwegazi nokuphucula imeko jikelele umntu.

Beta-blocker ngoku phambili ezininzi ezahlukeneyo. Enye ezisetyenziswa kakhulu kuphuhliso iingxaki kwentliziyo yi "Concor Kor." Ziveza, nokubuyekezwa medicament ziimpawu ichiza asebenze ngokwaneleyo kwaye bafune phakathi izigulane kunye nesifo intliziyo.

The main amacandelo kunye nefomu yokhululo iziyobisi

Eyona wengxenye yokulungiselela "Concor Kor" - hemifumarate bisoprolol. Njengoko kuphuma abangabancedani uluhlu enkulu ngokwaneleyo kwezinto: umbona starch, microcrystalline kwincindi, crospovidone, nemagnesium stearate, colloidal lesilicon dioxide, anhydrous calcium hydrogen phosphate.

Ichiza okunikelwa abathengi ngohlobo amacwecwe intliziyo-camera emhlophe umboniso-camera (kumafa layo - macrogol 400, dimethicone 100, gipromelaza, titanium dioxide). Umngcipheko omabini ihlukane amacwecwe amabini "Concor Kor." Packaging medicament evela namadyungudyungu ngefoyile, ngalinye ezinokuthi soldered-10, 14, 25 okanye 30 ziingceba.

Izigulane usoloko ebonwa ezikhemisti namayeza "Concor". Ekubeni amagama ala machiza zimbini ziyafana kakhulu, oosokhemisti basoloko ukuphendula imibuzo malunga umahluko phakathi "Concor 'ukusuka' Concor Kor." Ngoko, umahluko kuphela xa isixa somxholo we-component engundoqo esebenzayo - bisoprolol. "Konkor" abasebenzisi bangacela ukuthenga amacwecwe ukuba kumafa wayo 5 okanye-10 mg ze zithako esebenzayo, lo gama "Konkor Kor" - 2.5 mg.

kufuneka abathengi bazi ukuba ukuthengwa kwamayeza-blocker kwi ekhemesti ayinikiwe kuya kufuneka ukuba banike amayeza kagqirha.

pharmacodynamics

"Concor Kor" has a beta uyakhetha-adrenoceptor 1 yokuvimba impembelelo. Umongo neziphumo zayo - ukukwazi ukucinezela ukosuleleka neemvakalelo-luvo kwi nezamkeli adrenergic. Ngenxa yesi sizathu ichiza uyakwazi sizibhokoxe umfutho, antiarrhythmic, iziphumo antianginal.

ukusebenza unesifo "ncomo Concor Kor 'loogqirha ezinxulumene nesibakala sokuba bisoprolol lwehlisa umthamo umzuzu igazi. Ukongeza, inhibition enxuseneyo wenza inkqubo renin-angiotensin. Enempembelelo enkulu lwezonyango ifunyanwa emva kweentsuku ezi-5 zokufumana ichiza. BP leyo izinze ekupheleni kwenyanga yesibini amayeza unyango "Concor Kor."

Ppokazaniya medicament zokusetyenziswa njengesiqinisekiso ezinzileyo iziphumo antianginal ngokunciphisa kwemfuno ioksijini engabalulekanga ngenxa ukuhla kwireyithi intliziyo. Kwakhona, ndimele ndithi ukuba ukusetyenziswa kwale iyeza kukhuthaza isongezo diastole.

ukusebenza Antiarrhythmic lithetha "Konkor Kor" ngenxa yokuvimba kakubi ephembelela izinto ezibandakanya impembelelo kwenxenye ye ingcinezelo onovelwano yeSebe CNS, iinkqubo ingcinezelo ukudala pulses zombane esiludumbo sinus, lo inhibition umsebenzi wombane myocardium.

Ukuze ubonise ichiza, yaye ngubani - akukho?

Ziziphi indlela kwi "Concor Kor" ezibonisa ukuba ukusetyenziswa? ukubuyekeza Consumer ukuqinisekisa ukusebenza eliphezulu ichiza. Kuyanconywa ukuba ukunyanga ukusilela nentliziyo iyaluthintela uphuhliso iimeko ezinjalo usaqala. Ukuze sibe ngqo, abasebenzi bezempilo amisele beta-blocker ukwamkela unyango-enganyangekiyo ukusilela intliziyo ezingapheliyo kunye kwanciphisa umsebenzi iSystolic ventricular ngasekhohlo. Ngokuqhelekileyo "Konkor Kor" emiselweyo ngokunxuseneyo kunye inhibitors ACE , arhente umchamo, glycosides inhliziyo.

Ukuba akukho namnye waba nomnqweno ukwabela ichiza ngokwayo ngokwabo, ngaphandle imiyalelo ugqirha wakho, kuyimfuneko ukuba uqhelane kunye uluhlu onomtsalane Izimo kwi-arhente "Concor Kor."

Ngaphandle enyanzelekileyo kuzo zonke imiyalelo amayeza umlomo ubukho sokucalulana ukuba izakhi ezakha ichiza kunye nobudala yomguli (iminyaka ukuya ku-18 equka - ulwazi malunga nokusebenza kunye nokhuseleko), kusekho inala izizathu kunye neemeko apho ichiza bethatyathwe ngelize nje ayamkelekanga.

"Concor Kor" imiyalelo zokusetyenziswa (analogue - advanced beta-blocker - babe imiyalelo olufanayo inadmissibility wokwamkelwa) othintela izigulane ukusilela zentliziyo insufficiency etsolo kunye ezingapheliyo decompensated. Musa amisele yolwamkelo ichiza ukuwa nokothuka cardiogenic (a imeko osuswe yi kwekhono intliziyo). Umntu akakwazi ukuthatha beta-blocker ngenxa ezinxaxhileyo elikhulu AV-Uhanjiso (II, III isidanga AV-block) ngaphandle ipacemaker. Kwakhona isizathu sokuba zokwala yokwamkela kuba phambi bradycardia (izinga intliziyo (umyinge intliziyo) ungaphantsi kwama-50 ibetha / min.), Kwafa Sinoatrial (sinus zisiba umnqweno edlula umchiza sinoatrial). Amayeza contraindicated kwizigulane kunye Prinzmetal angina (spasm kweenqanawa ukuba ondle intliziyo, lo gama ST ingxenye ephakeme) kunye sinus lokugula syndrome (SSS).

Musa ukuthatha "Concor Kor" eliphantsi iSystolic uxinzelelo lwegazi (ngezantsi-90 mm HG. Art.), Xa ubukho besi sifo kwifomu kakhulu, abo imbali iirekhodi bezifo obstructive sifo pulmonary (COPD).

Further ukulungiselela "Konkor Kor" isicelo akwamkelekanga phambi ezingaqhelekanga kwinkqubo peripheral yokujikeleza (ikakhulu okwe amanqanaba kamva) kunye nesifo Raynaud kaThixo, pheochromocytoma (ithumba ingozi okanye abuhlungu APUD-system), kunye lactic pathways (Shift of balance acid-base kwicala asidi ukwandisa ngenxa beqokelela iimveliso emuncu zomzimba ngokubopha zabo okanye ukungabikho ukutshatyalaliswa).

Irejimeni yonyango yaye kuvumelekile umthamo bisoprolol

Ngokutsho imiyalelo, beta-blocker into ethathwa kanye ngemini, ekukhethwa ukuba kusasa, emva kokutya. Iipilisi "Concor Kor" (ukusuka uya kuba yintoni na iyeza ayizange isetyenziswe - nokuba loo nto sisifo kobuchopho intliziyo, ukusilela intliziyo esinganyangekiyo, okanye hypertension) Akuyomfuneko ukuhlafuna okanye lowatyumza yonke wabaginya kwaye zihlanjiwe phantsi omncinci amanzi.

Ukuphumeza amanyathelo zonyango ukusilela intliziyo ezingapheliyo kunye nokusetyenziswa ichiza "Concor Kor" kucetyiswa ukuba baphumeze titration lwe idosi. Kakuhle eli nkqubo ngolu hlobo lulandelayo: ngethuba 1 st ngeveki imali efunyenwe ibeta-blocker ngokwemiqathango bisoprolol ngu 1.25 mg ukuba yedosi ngeveki-2 kabini (2.5 mg) imizuzu 3 3,75 mg. Ngeli xesha evela kwiveki yesi-4 kude kube sekupheleni idosi 7 5 mg ngemihla Bisoprolol; 8 th ngeveki ukuya we-11 - 7.5 mg. Ukuqalela kwiveki 12 wamkela ubuninzi-10 mg. Idosi ichanekile kuyimfuneko (yaye kunokwenzeka) ukuze kwandiswe nje ekuqinisekiseni ukuba yangaphambili ngokuqhelekileyo kunyanyezelwa yaye oko kubangela iimvakalelo ezingakhiyo.

Apha phezu - ke impendulo yombuzo ngaphezu "Konkor" kwahlukile "Konkor Kor": yesibini lobeko (2.5 mg bisoprolol) ilungele ukuqalisa amanyathelo zonyango malunga gqolo ezingapheliyo sisifo sentliziyo ithi, ngelixa lokuqala (5 okanye 10 mg) sifaneleke ngakumbi ukuba unyango yesondlo.

Ukuba ngaxa ethile kwakukho uhlengahlengiso ithamo iimpawu ukusilela kwentliziyo, iingcali zonyango bacebisa ukuba idosi echanekileyo kwezi womchamo parallel okanye ACE inhibitors. Xa emva kwexesha elithile ukufumana uphuculo iwonga, kuyimfuneko ukuba kuqhubeka inkqubo titration "Concor Kor."

Therapy nalo eli chiza ubuntu ixesha elide. Ukupheliswa beta-blocker kufuneka iphunyezwe kancinci, ingakumbi izigulana nesifo sentliziyo kobuchopho.

ngeedosi kakhulu: imiphumela kunye nonyango

Imiyalelo ukuba ichiza uhlale ehamba ipilisi "Concor Kor." Ukusuka apho ke bathathe kwaye yintoni na Izimo, sasichaza ngaphambili. Ngoku siza kuqwalasela ukuba benze ntoni xa, ngenxa yezizathu ezithile, ngaba ithamo engamkelekanga enkulu kuye kwahlolwa.

Symptomatology yile ilandelayo: nokuphuhlisa lwegazi kunye bradycardia, bronchospasm, kunye namathuba eliphezulu hypoglycemia unakho ukuqala ukusilela kwentliziyo ahlekise.

Imiphumo efumene amathamo amakhulu abantu ezahlukeneyo zinokwahluka eziphathekayo. Mhlawumbi, abo babandezeleka sisifo sentliziyo, ecingela kakhulu ukuya ezingaphezu idosi ekucetyiswa ngugqirha wakho. Isigqibo ilungileyo umguli - ukubona ugqirha (ukuba oko kunokwenzeka ukuba yokuyenza ngokwakho) okanye kunokubangela i "fast". Kuxhomekeka ekubeni ziziphi isiyobisi uye wamkelwa, ugqirha uza kuqinisekisa amanyathelo ekufuneka athathwe ukuze ukuququzelela imeko yesigulane.

Imisebenzi Njengoko kuphuthuma ntolovelo lavage esiswini kunye ulwamkelo nezifunxi (carbon iyasebenza okanye analogue zayo). Ngaphezu koko, ngokuxhomekeke kwimeko, unyango bisoprolol kunganqunyanyiswa, kunye nexesha elifunekayo, esibhedlele kuya kuba unyango noncedo nomqondiso.

Imiyalelo "Concor Kor" ezibonisa ukusetyenziswa, iirivyu zonyango kunye neminye imithombo yolwazi imfutshane kwaziswa bonke yeengcali kunye nabathengi ukuba bisoprolol kunzima ngokwaneleyo iSADC dialysis.

obubonakala Negative application "Concor Kor"

Njengoko phantse nasiphi na isiyobisi, uyakwazi ukunika "Concor Kor" ziziphumo ebezingalindelekanga ngegalelo lazo kwi kwiinkqubo kunye namaziko.

Ngokumalunga yegazi, izikhalazo ezininzi rhoqo lwezigulane zokuqhambuka bradycardia kunye noxinzelelo lwegazi (ikakhulu kubantu abanengxaki sisifo sentliziyo esinganyangekiyo), unokuba vasospasm. Ukuze isiXhosa kungenzeka kukwaphula AV-Uhanjiso, decompensation kwentliziyo, kunye nokudumba peripheral.

Asabela ngayo CNS ichiza ibonakala ngaphantsi ngokukhawuleza kwaye zibandakanya ukudinwa, intloko ebuhlungu kunye nesiyezi, ukudinwa, ukuphazamiseka ekulaleni, kunye namaxesha uphaphama. kunqabile kakhulu, izigulane ezikhala amahlaba, amabi kunye nemibono. Kwiimeko ezininzi, ezi mpawu Awunayo i kombala olunzulu kwaye yavavanyelwa emva kweeveki 1-2 ukususela ekuqaleni unyango with "Concor Kor."

Iimpawu zibonisa ukuba ukusetyenziswa kunye noluhlu Izimo ingqalelo ingqalelo izigulane linembali ulwazi COPD kunye sombefu, kukho amathuba bronchospasm. Kunqabile uthethe imbonakalo nokuthimliswa komzimba.

Ngomhla inxalenye wokugaya ngokufuthi kunokubangela isicaphucaphu, ukugabha, ukuqhina, urhudo, imvakalelo kome imazi ibonakalisa em- ngomlomo. Ngaphantsi badla thetha uphuhliso kwesibindi betshintsha enzyme zesibindi.

Ukongeza zonke ngasentla, izigulane ingxelo ukuphazamiseka ezibonwayo kunye conjunctivitis (kunqabile), malunga mde kwizihlunu ithole kunye izihlunu ubuthathaka, waphula umthetho amandla (ezinqabileyo kakhulu).

Of ziyabagulisa rhoqo irhashalala, ukurhawuzelela kunye bomvu.

"Concor Kor" kunye nokukhulelwa

Beta-blocker "Concor Kor" ngexesha lokukhulelwa kunokwenzeka kuphela kwiimeko apho inzuzo kulindeleke ukuba unina impilo yakhe ngaphezu nobungozi ukuya umntwana okhulayo.

Nawuphi beta-blocker (kunye "Concor Kor" phakathi kwabo), ukunciphisa amandla igazi ukugeleza ngumkhaya ngaloo ndlela aze abe negalelo elibi kuphuhliso wosana Esibelekweni. Ukuba usafuna wabelwa ukuba bafumane amayeza abasetyhini abakhulelweyo, abasebenzi bezempilo kufuneka basoko belwakhele umkhanya igazi ukugeleza ngumkhaya kunye isibeleko, kwakunye ukuba bagcine ukukhula kunye nophuhliso lo mntwana. Xa kuthe kwakho naziphi na izinto ezimbi ngenxa yomfazi kunye nomntwana kufuneka badlulele kwezinye, iindlela ezizezinye zonyango.

Emva kokuzalwa umntwana kufuneka ahlolwe ngenyameko. Kwiintsuku zokuqala ezi-3 kosana nga ukunciphisa izinga glucose egazini, oko kwakhona bradycardia kunokwenzeka (lwehlisa izinga lentliziyo) iimpawu.

Njengoko webele-ukondla abafazi, ulwazi ulwabiwo bisoprolol ubisi lwebele okanye ukhuseleko lwalo ayifumaneki ukuba umntwana. Ngoko ke, ukuba kuyimfuneko, ukufumana indlela "Concor Kor" kweli xesha, kuyimfuneko ukuba isigqibo ekupheleni zisanyisa.

amachiza afanayo

Xa ichiza "Concor Kor" isasetyenziswa (zininzi) bavame zibekwe kwi eyona nto ephambili esebenzayo - bisoprolol. amayeza self iveliswa eJamani kunye eNorway. iziyobisi ezifana "Aritel" kakhulu lisoloko lisetyenziswa oothixo Russian, yaye "Aritel Kor", "Biprol", "bisoprolol-Prana". Nangona yokugqibela lufumaneka kumazwe amaninzi ehlabathini lonke, "bisoprolol Teva" - iHungary, Sirayeli, "bisoprolol-ing '- Ukraine. Eneneni, ixesha kwiwotshi yamanani ngqo ngu "Concor".

Ngaphezu koko, ukususela ngoyena usetyenziswa rhoqo ngendlela efanayo ingabizwa "Bidop" yaye "Bidop Kor" "START_ITALICJ" "Bisogamma", "Bisomor", "Kordinorm" yaye "Kordinorm Kor", "Tiresias", "Niperten".

Ngokubanzi, uluhlu analogue (izithethantonye) kubanzi kakhulu kwaye ezahlukahlukeneyo, kodwa ukusombulula umbuzo wokuba yintoni endaweni "Concor Kor" self engamkelekanga. Ukukhetha ilungelo medicament xa kumiselwa kuphela kukagqirha kokuya.

Intsebenziswano kunye namanye amachiza

On the ukusebenza okulungileyo tolerability ibeta-blocker kungachaphazela ukusetyenziswa amachiza amabini ngaxeshanye. Ngokumalunga ichiza "Concor Kor" (ezibonisa ukusetyenziswa, abasebenzi bezempilo yokwenene kwaye izigulane ukuqinisekisa ukusabela enjalo) ukunganyamezelani zingenzeka nokuba efanayo impembelelo amachiza umgaqo ziye zathathwa kusetyenziswa imali encinane ixesha nganye enye.

Ngaphezu koko, izigulane ezithatha bisoprolol, kuyimfuneko ukwazi oko zamavumba ukuba immunotherapy okanye izicatshulwa zeemvavanyo ulusu isekude uphuhliso negazi systemic eziqatha okanye anaphylaxis. Oku kunokubangela ukothuka anaphylactic kunye isicelo ngaxeshanye arhente bisoprolol kunye umahluko iodinated lolawulo efakwa.

Womchamo, iziyobisi sympatholytic kunye nezinye umfutho, bisoprolol ukusetyenziswa kudibaniso nge, kunokubangela ngokugqithisileyo ukwehlisa uxinzelelo lwegazi.

lakhula Tetracycline, antipsychotics, nadlamkisayo kunye neziyobisi hypnotics zisidimaze inkqubo luvo. Isiphumo insulin okanye nezinye iziyobisi ezifana hypoglycemic lolawulo yomlomo ngexesha unyango kunye medicament "Konkor Kor" nande. Symptomatology okhulayo hypoglycemia (tachycardia ingakumbi) kunokoyiswa okanye ezigqunyiweyo.

Yintoni ufune?

Abantu abathi "Concor Kor" yabelwa i sicelo azamkeleki ngokwazo ukuba ukuphazamisa unyango okanye ukutshintsha idosi ekucetyiswa ngaphandle kuqala kokuthetha nogqirha wakho. Kwiimeko ezinjalo ke kunokwenzeka zisiba lomsebenzi intliziyo. Oku kuyinyani ngakumbi kwezigulane kwemithambo. Ukuba kuthe kwanyanzeleka ukuba ukuphelisa amayeza unyango "Concor Kor", umenzi lithethelela ukuba wenza oku, ngokuthe ngcembe ngokunciphisa idosi.

E ukutshaya izigulane ukusebenza beta-blocker ngaphantsi kwabo anditshayi.

Abo banxiba lenses, kufuneka sikhumbule ukuba beta-blocker kunokubangela ukuhla ekuveliseni ulwelo iinyembezi.

Ukuba isiguli imfuneko yokuba utyando imbalo, sisamkela "Concor Kor" kufuneka siyeke ukusebenzisa iiyure zonke hayi ngaphantsi kwe-48 phambi kokuba kumzimba wonke. Ukuba utyando ifuneka ngokungxamisekileyo, kwaye isigulane sele ifumene beta-blocker, kuba zomzimba jikelele kuyimfuneko ukukhetha neziyobisi kunye nempembelelo embi sakugcina inotropic.

Elokuphetha ndifuna ukuthi nantoni kwafuneka amayeza "Concor Kor" Ufundo, reviews of ukusebenza phezulu inxalenye kwizigulane kunye nabasebenzi bezempilo, isigqibo sokuqeshwa lwegama lomntu ngamnye kuthetha "Concor Kor 'hayi nayiphi na enye beta popup, kufuneka ibe kuphela kukagqirha kokuya.