I-Helicobacter pylori (i-Hp) yi -britrium ye-gram-negative negative form of concave okanye ukuma kwimoya ehlala kwisigxina somntu kunye namanye amantombazane. Iine-flagella ezine-4-6, ngendlela ehamba ngayo njenge-coorkscrew, engena ngaphantsi kwimbumba yesisu esiswini kunye ne-duodenum, kukho neenkcukacha malunga nekoloniyamu ye-epithelium yesigidi somlomo, i-pharynx, isophagus kunye ne-rectum. Iipropati ze-biochemical zale bhaktiriya ziquka ukukhululwa kwe-enzymes esebenzayo-urease, protease, alkaline phosphatase, i- oxidase, i-catalase, i-gamma-glutamyltransferase. Zizo zi-enzymes ezibeka umphumo we-pathogenic kwi-membrane yamalungu ebantu kwaye zibangele ukuvuvukala kwazo kwi-hypersecretory hlobo: i-gastritis, i-bulbitis, i-duodenitis, ezayo ekukhokelela ekuphuhlisweni kwesilonda se-peptic. Kule nxu lumene, iyeza laqala ukuphuhlisa indlela yokuthintela kunye nokunyangwa kwe-Helicobacter pylori ukusuleleka - unyango lokuphelisa, oluyinkimbinkimbi yamachiza alwa ngokukrakra neengxube ze-microbe kunye negalelo ekwenzeni ukugqithisa kwe-pH yesondlo sesisu, ekugqibeleni kukukhokelela ekugqibeleni ukukhutshwa kwebhaktiriya .
Iirhulmenti zonyango Hp
Ukuxothwa kwonyango kuthinta zombini i-microorganism ngokwayo kunye neziphumo zesenzo sayo se-pathogenic. Oku kungenxa yamacandelo ayo: i-antibiotics iyonakalisa iibhaktheriya, kunye neproton pump inhibitors iyanciphisa ubunqunu besisu kunye ne-duodenum, ukukhusela ukuphuhliswa kwezilonda kwaye, ngoko, ukudala iimeko ezingenakwenzeka kwi-microbe. Kwaye ekubeni unyango lokupheliswa kwenkqubo luqukethe amaninzi amachiza okulwa ne-antibacterial, ukufunyanwa kwezidakamizwa ngokufanayo kufumaneka ukukhusela ukuphuhliswa kwe-dysbacteriosis. Okwangoku, izazinzulu zonyango ziye zaphuhlisa izicwangciso ezimbini ezibalulekileyo zokutshatyalaliswa kwe-Hp. Ngako-ke, unyango olusisigxina se-anti-antibiotics (i-clarithromycin + amoxicillin / metronidazole) kunye ne-inhibitor yepropy pump (ezinje izidakamizwa njenge "Omeprazole", "Rabeprazole", "Pantoprazole" kwaye I-Etc.) kumgangatho oqhelekileyo kabini ngosuku. Akunakusebenza kuphela kwiimeko ezimbini: ukuba isigulane asihambisani nemigaqo yokuthatha unyango, okanye ukuba kukho ukuchasana kwe-Hp strain kwenye ye-antibacterial agents.
Quadrotherapy
Kwimeko ekhankanywe ngasentla, isicwangciso se-ezine-crapy ofrapy eradication sinikezelwa, esongeza ngokuquka i-bismuth dicitrate, isilwanyana esilwa nesilonda esinomsebenzi ophezulu kunye ne-Hp kwaye sijoliswe ekubhujisweni kwimbumba. Le myeza inokusetyenziswa okulawulwa ngokukhawuleza ngenxa yeziphumo zayo ezinobungozi kwinkqubo ye-nervous central kwiimeko zokulawula ixesha elide kumanani amakhulu, ngenxa yokuba i-bismuth inomhlaba wokuqokelela kwiisishu ze-neural kwaye ibangele ukuxiliswa kweziyobisi. Nangona kunjalo, unyango lwe-peptic ulcer luyingxenye ebalulekileyo yonyango lwayo, kuba okokuqala kukho konke kuyimfuneko ukuchaphazela i-etiology yesifo.