Anticonvulsants "Topamax": Imiyalelo yokusebenzisa

Ukulungiselela "Topamax" umyalelo libhekisela kwiqela amayeza anticonvulsant, apho inyathelo sibhekiswe ethintela receptors isodiyam inkantsi ukususwa kunye nokuphelisa nemithambo excitation. Isiseko sale iyeza ukwanda umsebenzi γ-aminobutyric acid kunye nomsebenzi anhydrase inhibition గుర్తులు ibhaloni le isoenzymes. Ngaphaya koko, i-arhente antiepileptic "Topamax" (umsebenzisi ndingahambi amisiweyo, it qinisekisa) ivumela kwezwi lohlobo neGibheha receptor uvakalelo. Kusetyenziso kule iyeza kwi isigulana esiphawuliweyo anti-ukudumba, iintlungu kunye nesiphumo antispasmodic.

Ifumaneka iziyobisi "Topamax" (umsebenzisi malunga oku kubonisa) ngokohlobo njengezingxobo gelatin, ezinayo njengoko component iphambili umlinganiselo topiramate milligrams ezingamashumi amabini anesihlanu okanye amashumi amahlanu. izithako Auxiliary zezi neselulosi acetate, iswekile kunye povidone granules. Ukubunjwa yeqokobhe philisi zibandakanya izixhobo ezifana sodium lauryl sulfate, gelatin, monolaureat sorbitan, amanzi, titanium dioxide kunye inki.

Ukumisela anticonvulsant "Topamax" yemiyalezo ucebisa ikakhulu unyango izigulane unesifo "sokuwa" okanye "igama Lennox-Gastaut syndrome." Ukongeza, ugqirha ngokubonakalayo lokumisela esi ngeyeza abantu abaphethwe uqaqanjelwa, sokuwa indihlaziya-clonic, buso okanye myoclonic. Ngaphezu koko, eli yeza antiepileptic alwa kunye nokungabikho yaye bayakwazi ngexesha elifutshane ukuphelisa aqaqambayo.

Thatha njengezingxobo "Topamax" umyalelo esokuba akabufuni abantu hypersensitivity ukuba topiramate okanye uxabane nawo nawuphi na izithako eziqulethwe kwengoma. Kwakhona esiconywayo i anticonvulsant kwabasetyhini kuzala umntwana. Uluhlu Izimo ziquka ixesha kakhulu kwaye zisanyisa, kwaye kweminyaka emibini. Ngononophelo kakhulu kufuneka uthathe amayeza abantu nefrourolitiazom, insufficiency hepatic okanye sezintso.

Dedani ekufumaneni ichiza antiepileptic iziguli kufanele kunye hypercalciuria.

Ngokumalunga ngayo kunokwenzeka egwenxa okubangelwa ukusebenzisa iziyobisi "Topamax", apha kwindawo yokuqala, loo ithi kufuneka yabelwe njengokuba nesiyezi, ingqalelo kakuhle, paraesthesia, silale, ukudinwa, ucaphuka yaye ukozela. Ukongeza, Inokwenzeka yehle wokutya, silale, Ukuphazamiseka kwengqondo, gipoesteziya, dysarthria, lafa, nokudideka, kunye lability ngokweemvakalelo. Kabi esiswini, gastritis, umlomo owomileyo, nokopha, glossodiniya nokuqunjelwa kwakhona ukwasuleleka ngabantu abathatha njengezingxobo "Topamax". ezi pilisi abe unobangela amahlaba izihlunu, uphuhliso myalgia okanye arthralgia, umkhuhlane kunye nobunzima uphefumlayo.