Amachiza "i-Indapamide": ukususela kukuphi ukukhupha kunye nendlela yokuthatha

Amachiza "i-Indapamide" ayichaphazela iindonga zee-vascular, aziphumule kwaye aziqhelanise ukunyaniseka kwezihlunu. Siyabulela kule nkunkuma, i-arterioles yonyuka, ekhokelela ekuhambeni kwegazi okungenakuguqulwa emzimbeni. Amacwecwe "i-Indapamide" - iyeza lokunyanzeliswa. I-vasodilator, efana ne-pharmacodynamics ukuya kwi-thiazide diuretic. Ngomhla inani lemvini eliveliswe landa kancinci. Kanye nalo, ion i-sodium ephezulu, i-chlorine kunye ne-potassium zisuswe emzimbeni. Ngexesha lokuthabatha iziyobisi, i-carbohydrate kunye ne-fatabetism ye-fatabus ehlala yinto eqhelekileyo, eyenza ukuba isigulane sithathe isigxina ngokukhuluphala okanye isifo sikashukela. Ngokunyuka okuphawulekayo kwi-ventricle yekhohlo yentliziyo, iyeza "I-Indapamide" liyanciphisa kakhulu izinga le-hypertrophy. Ngokusetyenziswa rhoqo kweziyobisi, umphumo uphumelela emva kweveki ezi-2, kwaye emva kweveki ezi-10, umphumo ophezulu uncedo uyabonwa. Isilinganiso esisodwa samachiza "i-Indapamide" sigcina impahla yonyango ukuya kwiiyure ezingama-24.

Pharmacokinetics

Isilwanyana esivela kwingcinezelo "i-Indapamide" ixakeka ngokukhawuleza kwisigxina sesisu kwaye idityaniswe emzimbeni ikakhulukazi ngomchamo. Umxholo weemetabolites ezingasebenziyo kwizilwanyana zingama-20%. I-diuretic inxulumene ne-plasma kunye ne-erythrocytes, ingena kubisi lwebele. Ngokusetyenziswa rhoqo kweziyobisi, i-cumulation ayibonakali. Izigulane ezinobungozi obuqilileyo maziqaphele ngokusebenzisa le mayeza ukuphepha ukubunjwa kwesibindi.

Iimpawu zokusetyenziswa

Kutheni iyeza "Indapamide" linceda? Izimpawu zokusetyenziswa kwazo zi:

• Uxinzelelo lwengqondo.
• Ukungaphumeleli kwintliziyo engapheliyo (ukugcinwa kwesodium kunye nokugcinwa kwamanzi emzimbeni).

Ukungqinelana

Ukwamkelwa kwesi sidakamizwa kuncinci kwezi zifo zilandelayo:

• Ukuphululwa kwemisebenzi yesibindi.
• Umsebenzi onobuqhetseba obunzima.
• Ukunyamezela kwiinqununu zeziyobisi.
• Hypokalemia.
• Ukuphazamiseka kokujikeleza kwegazi kwintliziyo kunye nomgogodla.
• Gout.

Kwiimeko ziphi iingxaki ezinokwenzeka xa usebenzisa iyeza "Indapamide"

Yintoni ekucebnyiwe ukuba ithathe le chiza, sele sifumene. Kodwa xa ufuna ukunyamekela xa usebenzisa? Iimeko ezinjalo ziquka:

• Ukunganyamezeli kwaLactose.
• Ukukhulelwa kunye nokulahlwa.
• Ubudala ukuya kwiminyaka eyi-18.
• Ukulinganisela kwamanzi-electrolyte.

UkuHlanywa noLawulo

Isilwayo sithathwa ngomlomo kanye ngosuku ngosuku lwe 2.5 mg. Ukwamkelwa kwasekuseni kusebenza ngokugqithiseleyo, kuba inani elikhulu lokutya linciphisa ukutyunjwa kweyeza. Iipilisi kufuneka zigonywe, kungekhona umbane, zifakwe ngamanzi aneleyo. Ukwandisa umthamo weyeza "I-Indapamide" akukhokelela ekunyuseni kwefuthe lokunyanga, kodwa kubangele imiphumo emibini. Izigulane eziphelelwa yintliziyo yokuhluleka, ezingenakho ukuphuculwa, zinqunywe umthamo we-5 mg ngosuku.

Izimpembelelo ezimbi

Xa uthatha isilwanyana "i-Indapamide" (echazwe kuyo, esele saziyo), isiphumo esisecaleni sinokwenzeka. Okokuqala, oku kwenzeka ngeendlela zokwandisa umthamo weyeza, ukunyanzelwana kwezinto ezinobungozi, isiphumo samalungu ngamnye kwinkqubo ethile yeenjongo. Imiphumo emibi ingabonakalisa ngeendlela ezahlukeneyo.

• Inkqubo yesantya ephakathi: intloko, ukulala, i-asthenia, ukulala, ukuthukuthela.
• Inkqubo yokuphefumula: i-pharyngitis, ukukhwehlela okukhulu.
• Inkqubo yokugaya i-digestive: i-nausea, ukuhlanza, isifo sohudo.
• I-urinary system: i-nocturia, ukuvuvukala okusulelayo.
• Inkqubo ye-Cardiovascular system: i-arrhythmia, intliziyo yesifo, i-hypokalemia.
• Izifo zesikhumba: ukubetha, urticaria, ukukhawuleza.

Iindleko

Ixabiso eliqhelekileyo lonyango "i-Indapamid" eRashiya - iiruble eziyi-12. Iphakheji iqukethe iipilisi ezi-30 ezi-2.5 mg nganye.

Ukusebenzisana namanye amachiza

Izidakamizwa ezichasayo zinciphisa umphumo weyeza "Indapamide", khawuleza usebenzise umbane emzimbeni, ngenxa yoko kufuneka uzalise kwakhona. Xa uthatha amacwecwe e "Indapamide", kuthini ukuhambelana nezinye iziyobisi? Ukubunjwa kwe-diuretic kunzima kakhulu, ngoko ke unyango olukhethiweyo lukhethwe ngumcebisi ngokuthe ngqo, ngokuqhubekayo kwimithi enqunyiwe.

• Ukulungiselela kunye nomxholo we-lithium ngokukhawuleza kuxoxwa kumchamo, ngoko kuyimfuneko ukubeka iliso kwinqanaba lezinto kwi-serum yegazi.
• I-SCS, ngokuchasene nayo, ilinda amanzi emzimbeni, ukunciphisa umonakalo ochasayo.
• I-cardiac glycosides inciphisa inani le-potassium emzimbeni, oku kunokukhokelela kwi-hypokalemia.
• I-calcium: ukwanda kwimixholo yeetyu emzimbeni.
• Amalungiselelo e-Radiopaque anexabiso elikhulu le-iodine linakhokelela ekuphuhliseni ukuhluleka komntu.
• I-Tricyclic antidepressants yenza ingozi ye-orthostatic hypotension.

Imiyalelo ekhethekileyo

Ziziphi izigulane zifuna ukuqapha ngokucophelela imeko xa uthatha isiza "Indapamide"? Ukusuka kwizinto abafuna ukukhuselwa ngazo? Izigulane ezine-cirrhosis zesibindi, intliziyo, iinjongo, ukungaphumeleli kwesibindi kuyadingeka ukuba unyango kunye neyeza "I-Indapamide" ngokungqongqo phantsi kolawulo loogqirha. Ukubonakala kokungcoliswa kwamanzi emzimbeni kubangela ukugqithiswa kwemisebenzi yombutho. Kubalulekile ukulawula umxholo omninzi emzimbeni kwaye uhlawule ngexesha.