"Vaydaza" (azacitidine): oothixo ixabiso. Apho ukuthenga Vaydaza engabizi?

"Vaydaza" - an antimetabolite, evele lyophilisate (ngumgubo special) ukuze oluludaka okanye sele ngohlobo ugqibile ukunqunyanyiswa lolawulo ongama. Le esisebenza imveliso isihloko - azacytidine nghena umzimba, lenkosikazi i-enzayim uxanduva kwiinkqubo pathways kwizisele umhlaza, kwaye ime ukukhula kwabo kunye nokusebenza.

ubungqina

"Vaydaza" imiyalelo Drug zokusetyenziswa eziza kufundiswa kamva kweli nqaku, umiselwa izigulane abadala:

• leukemia myeloid olunamandla;
• syndrome myelodysplastic;
• leukemia ezingapheliyo myelomonocytic.

Ngokubanzi, unyango lwenziwa ngokuthi isixhobo olunikiweyo nakwenzeka abohlukeneyo kwizigulane kunye iiseli Isiqu hematopoietic.

Kutheni ixabiso "Vaydaza" iziyobisi generic angaphantsi kwe ukwenzela sokuthengisa

Ngoko ke akukho mfihlakalo ukuba amachiza amaninzi anticancer ayabiza. Maxa wambi oku kukhokelela izigulane ukuba ezibathe sele yabelwe, imeko enzima, ngenxa yokuba akukho bani ukuthenga impahla.

Kwiimeko ezinjalo ukuza ahlangule generics. It amalungiselelo ngezithako efanayo ngokupheleleyo kwaye yakhululwa ngokusebenzisa ubugcisa main onophawu. Le nkampani ukuba silwenza kubo, uthenga iphepha-mvume, kodwa musa ukuchitha imali ukuba siyiphuhlisa ngaphakathi kuphela, ukuze bafunde ifuthe inkampani amayeza kunye nentengiso, ngoko ke ixabiso generics usezantsi kakhulu ngaphezu ichiza uphawu.

Umzekelo, inkampani Indian Natco Pharma iqala kwimarike XPREZA yendawo - generic "Vaydaza" iziyobisi, nto leyo zingathengwa kwisiza WWW.ONKO24.COM. Apha izigulane ngamaxabiso afikelelekayo inikezwa inani elikhulu profile esibhedlele amayeza, nabakwaziyo ukwandisa nokuphucula umgangatho wobomi izigulane nezibi.

Iimpawu ze isicelo kunye umthamo ichiza

Ukulungiselela "Vaydaza" lesitofu kwesikhumba apha emagxeni, hip okanye esisu. Sikuyo ndawo kuyimfuneko ukuba isitofu enye kunye isiza ngasinye inaliti elandelayo ifanele ibe kumgama ngaphezu 2.5 cm kowangaphambili.

Nceda uqaphele ukuba ichiza kufuneka ilawulwe endaweni lamatywina, ukuba bomvu, ukopha okanye enye umonakalo.

Phambi Inaliti lithetha "Vaydaza" Kucetyiswa ukuba ukuthatha amachiza antiemetic.

Ngokuba zonke izigulane ngexesha lokuqala unyango, nokuba yemida igazi, idosi yokuqala 75 mg / m² phezu komzimba lonke kwaye sifakwe phakathi evekini, yonke imihla. Oku kulandelwa ikhefu iintsuku ezingama-21, emva koko umjikelo iphindiwe.

Ngokuqhelekileyo, isigulane kwimijikelo 6 ezifunekayo. Kodwa ke unyango kwaqhubeka nje impumelelo obubonakalayo nothomalaliso, okanye kude kube bubungqina phambili kwesifo.

Ukulungiswa sisombululo ziphene

Kuba inkqubo imixholo igutyana kufuneka ichithwe ngamanzi ukuba isitofu (ml-4). Ukuba iqela 25 mg / 1 ml ukunqunyanyiswa kufuneka ngamandla ukuyishukumisa de de kube yohlobo olunye yaye akafuni abe umbala omhlophe. Ukuba kuyimfuneko, ukufumana idosi ngaphezulu kwe-100 mg kufuneka athathwe igutyana iindlela 2 "Vaydaza".

Izimo

Kwezinye iimeko, ukuqeshwa "Vaydaza" iziyobisi, ukuqeqesha inikezelwa kweli nqaku ayivumelekanga. Ngokuqhelekileyo, oku kwenzeka kwizigulane ezinjalo:

• kunye metastases kangaka esibindini;
• ebuntwaneni;
• kokuba i uvakalelo landa eyona nto iphambili ebonakalayo ichiza okanye enye inxalenye yalo;
• ngethuba lokukhulelwa zisanyisa.

isicelo ngenyameko arhente isihloko kubaguli ngentliziyo, lung, sezintso zesibindi.

imiphumela emibi

Iziganeko zixhaphakileyo ezingalunganga ngexesha unyango kunye 'Vaydaza "myalelo ulandelayo iminxeba:

• isicaphucaphu nokugabha;
• kwesisu okanye ukurhuda;
• walunywa;
• anorexia;
• isiyezi kunye intloko ebuhlungu;
• ukozela, yobuthathaka;
• umkhuhlane;
• ixhala, zokulala;
• ukuphelelwa umoya;
• ukulunywa;
• petechiae;
• arthralgia;
• nasopharyngitis;
• pneumonia;
• anorexia.