Syndrome Gilbert kaThixo. isifo sakhe, iziphumo

Gilbert engqondweni, oko ukuba esi sifo? Gilbert kaThixo syndrome - uhlobo lwezonyango hyperbilirubinemia kakhulu mnene olusebenzayo. Isifo ubonisa UGT1A1 gene wezakhi. Ngenxa yakhe, i-enzayim ufakwe yi i UDP. Gilbert engqondweni luphawulwa kulandelayo:

1. imigangatho ephakamileyo bilurbina igazi
2. Partial Ukungaphumeleli glyukuroniltransferazy
3. Ukungabikho utshintsho hepatic
4. Ukunciphisa yibilirubin ephakamileyo ngenxa yesenzo phenobarbital

Ngokuba lixesha lokuqala Gilbert engqondweni kwafumaneka 1901, oogqirha French Gilbert Nicolas Augustin kunye Lereboullet P. Baya wachaza sifo ngokuthi "cholehemia ekhaya". Emva koko, kwacetyiswa amagama ambalwa, kodwa wayeka kwi Gilbert engqondweni. Esi sifo kuvame kumadoda abaminyaka 25-30 iminyaka.

Iimpawu ezithile izifo

Xa abantu, kukho ukudinwa, ilungelo eliphezulu ikota yesangqa yokulunywa zenzeke. Nokubonakaliswa iphambili syndrome ixhala kunye nombala zipeyintwe. Maxa wambi kuyenzeka ukuba yellowness sikakrebe, kwaye umntu efunda malunga nesifo kuphela emva kokuba kubanjwe omzimba ezinto eziphilayo. Kukho iindidi ezimbini sifo: episodic kunye ezigulo ezondeleyo. Ukuba umntu sithwalisa emzimbeni umzimba wakho, le senyongo zingenzeka. Ukongeza, ukusebenzisa kakubi utywala, yindlala inokuba i "ukuqala 'ukuze uphuhliso sifo.

Gilbert kaThixo syndrome kokuxilongwa.

bilubirin Ngokubanzi ngexesha sifo ibe kwinqanaba 21-51 mmol / l, apho kunokwenzeka ukunyusa umgangatho 85-130 micromoles / ilitha. Ukuchonga oku sifo, kufuneka bapase i isifo okhethekileyo. Kunokuba ibe iintlobo ezininzi.

1. Test ne yindlala. Ubukhulu becala kusetyenziswa ephantsi-ukutya okunamafutha, ubuncinane - ezile iiyure eziyi-48. Ngaloo uyondelelwano lwee- yibilirubin landa egazini.
2. Test ne pentobarbital. Ukusetyenziswa kwale iyeza kukhokelela ukukhuthazwa umsebenzi enzyme glyukuroniltrasferazu, ngokwenjenjalo kuncitshiswe izinga yibilirubin.

unyango lwesifo

Naluphi na unyango olukhethekileyo, ngokubanzi, hayi, kuba luphawu ephilayo, kungekhona isifo. umthwalo egula nje extra contraindicated, kufuneka ulandele ukutya okhethekileyo. iziselo ezinxilisayo ukuba umntu onjalo kufuneka kuthintelwe ngenxa yokuba ukusetyenziswa kwazo kunokukhokelela kuphuhliso kwesi sifo. Kodwa ke kubalulekile ukukhumbula ukuba amatyala ka Gilbert kaThixo syndrome akuyomfuneko ukwala logonyo. Ngexesha okhulisa oogqirha senyongo amisele ukutya ethile, vitamin uthomalaliso emiselweyo.

imiphumela syndrome Gilbert kaThixo

Abo bamfumanayo syndrome Gilbert kaThixo, imiphumo inzala, kwakunye nendlela isifo iya kuchaphazela isibindi. Ezinye imiphumo ayikwazi kuba konke konke, kodwa kungcono ukwenza ultrasound kwesibindi, kwakunye uvavanyo igazi yibilirubin. Ukuze kwesibindi wahlala kakuhle xa efumanise Gilbert engqondweni, kufuneka unamathele ukutya, kwaye qinisekisa ukuba umthambo. Ngamanye amaxesha iziphumo zesi sifo ngazo njengoko idlule mbala steatosis. Ngokusisiseko, ezi ziphumo kuvandlakanywa abantu. Ngoko ke, abantu abaphethwe ukusuka syndrome kufuneka iliso impilo yabo.

Yintoni na uqikelelo ubeke abagulayo?

Esi sifo kuthathelwa ingqalelo uhlobo eqhelekileyo. Aba bantu zithathwa ukuba babe sempilweni kakhulu, ngakumbi kwi unyango ekhethekileyo akuyomfuneko. Nangona isibakala sokuba hyperbilirubinemia zigcinwe ubomi, Gilbert engqondweni nto ikhokelele ekufeni. Kukho amathuba iingxaki zengqondo, kunye cholelithiasis. Imiphumo yale sifo zingabonakali kuze engama-20, kodwa usoloko sikhatshwe ngumntu, ngakumbi ukuba senze ufuzo factor. Eyona nto ibalulekileyo kukuba esi sifo ikakhulukazi nefuthe kumsebenzi zabantu.