"Moxonidine": imiyalelo, real

Yintoni unyango "Moxonidine"? Imiyalelo yokusebenzisa esi sixhobo, kwakhona ngaloo nto, Izimo, kunye analogs zichaziwe ngokucacileyo kweli nqaku. Ukongeza, siza kukuxelela malunga kuthetha into sicinga kujongwe, ukuba unazo naziphi na iziphumo ebezingalindelekanga kunye nefom apho kokuba ikhutshwe.

Imilo kunye nokwakhiwa ichiza

kunokwenzeka ukuba uthenge ichiza "Moxonidine" Ngayiphi indlela? Eli chiza kuthengiswa kuphela ngokohlobo amacwecwe. element lwabo esebenzayo lulwelo ezifana moxonidine. Ngokumalunga amacandelo ezongezelelweyo ezinxulumene noko neselulosi microcrystalline, uCastor ioli, Aerosil A-380, hydroxypropylcellulose, nemagnesium stearate kunye kathi-80.

Iipilisi zithengiselwa uqiniseke kwikhadibhodi. Omnye iphakheji babe 98, 60, 56, 42, 40, 30, 28, 20, 14 kunye namacwecwe-10.

Iimpawu amayeza ye ichiza

Kutheni kufuneka iyeza "Moxonidine"? Imiyalelo yokusebenzisa ithi le ukulungiselela ichiza umfutho. indlela yayo amanyathelo kuxhomekeke kwinto yokuba lithetha into esebenzayo kuchaphazela amakhonkco esembindini kumgaqo uxinzelelo lwegazi. Ngamanye amazwi, moxonidine - imidazoline receptor agonist yi (ikakhulu).

Ichiza abangaphangeliyo umsebenzi kwiziko vasomotor, ukunciphisa esihla isiphumo onovelwano nemithambo yegazi. Uxinzelelo (ukuzala kunye iSystolic) kunciphisa kancinci.

medicament ingqalelo yi kuthi yahlukile kwezinye izinto umfutho sympatholytic ngokuthi unembinana nje kuphela sendiselane oluncinane alpha-2-adrenoretseptoramm. Oku kuchaza okuba ephantsi ngumlomo owomileyo kunye umthomalalisi.

Asikwazi ukuba moxonidine kungandisa index insulin uvakalelo (malunga nama-21 ekhulwini) kubantu abane ukutyeba.

Pharmacokinetics beziyobisi

Apho ichiza ako, "Moxonidine"? isicelo Umsebenzisi ithi emva kokufumana medicament wendele nangoko kwaye phantse ngokupheleleyo kwisiqwenga eliphezulu lokugaya.

Bioavailability (elililo) zesixhobo 88 ekhulwini. Le xi eliphezulu ifunyanwa emva kwemizuzu amathandathu anesihlanu. Kulo mzekelo, ukuselwa kutya nafuthe pharmacokinetics ye element esebenzayo alukhange.

Unxibelelwano kwiproteni igazi yi malunga ne-7.3%. Le metabolite enkulu Moxonidine Moxonidine wenza avela emzimbeni, kunye guanidine.

Isiqingatha-ubomi moxonidine kunye metabolites yayo engu 150 300 ngokulandelelana.

Emva kokungenisa ezingamashumi amabini anesine iiyure iziyobisi kwazona yi izintso zibe ngumqulu ka-90%. Kwakhona, le into esebenzayo uyaphuma kwaye emathunjini.

Ubungqina obubonakalayo buxela ukuba kusetyenziswe isixhobo yezonyango

Kwezinye iimeko, prescribers 'Moxonidine "? Ukusetyenziswa kweli chiza luboniswa kuphela xa ngezifo ezifana umfutho wegazi.

Izimo ukusetyenziswa isixhobo yezonyango

Kwezinye iimeko, oogqirha musa amachiza izigulane zabo 'Moxonidine "? Imiyalelo yokusebenzisa eli chiza iqulethe akukho uluhlu olude kakhulu Izimo. Cinga ngoku.

Ngoko Izimo kusetyenziso yokulungiselela "Moxonidine 'ukuba ezi zinto zilandelayo:

• wavakalisa AV-block 2 kunye degrees 3, SSS;
• bradycardia (ngaphantsi kwama-50 ibetha ngomzuzu);
• kolutsha kunye nobudala babantwana (eyi-18);
• ukusilela intliziyo ezingapheliyo kunye oyingozi;
• baby etyisa xesha;
• Hypersensitivity ukuya element esebenzayo.

Ichiza "Moxonidine": imiyalelo yokusebenzisa

Baqinisekiswa ngale medicament iza kwenziwa ekupheleni kweli nqaku. Ngoku ndifuna ukukuxelela malunga nendlela yokusebenzisa eli chiza phambi kwethu kakuhle.

Drug "Moxonidine" ngaphakathi kuphela. Esithathwa xa kunyango ngamachiza ekuqaleni kufuneka micrograms 200 kanye ngosuku. Ekuhambeni kwexesha, ungathatha micrograms 400.

Loo nto iya kufuna ukulungiswa ngamnye yonke imihla iyeza ngokuxhomekeke tolerability unyango ngamachiza. Ngokutsho imiyalelo, idosi iphezulu medicament ngosuku yi 600 mg (izigaba ezibini).

Izigulana insufficiency sezintso (esiphakathi kwaye kakhulu), yaye abantu phezu wehemodialysis, ichiza elo lilawulwa isixa 200 mg kanye ngemini. Ukuba kuyimfuneko (ngonyamezelo elungileyo), idosi elikhankanyiweyo angandiswa ukuya iphezulu (ngamanye 400 mg).

nemiphumela emibi emva kokufumana medicament

Ngaba iziphumo ebezingalindelekanga ichiza "Moxonidine"? Baqinisekiswa ngaye bathi ngamanye amaxesha amayeza ngokwenene ebangela ukonakala kweendlela zempilo. Cinga uluhlu lweziphumo ebezingalindelekanga iqulethe imiyalelo:

• luvo (central): yintloko, niphele, isiyezi, kunye somnolence.
• wokugaya: ukugabha, umlomo owomileyo, urhudo, ukuqunjelwa kunye isicaphucaphu.
• nemithambo yegazi: bradycardia, drop iphawulwe uxinzelelo lwegazi, hypotension intolerance.
• Nesikhumba inyama ongama ukuphazamiseka: nokudumba angioneurotic, pruritus nesikhumba angawokubhuda.
• izifo zengqondo: Uvalo and ugwayi.
• Mibono ukuphazamiseka welungu bezandi: unkenteza ezindlebeni (kuyenzeka kunqabile kakhulu).
• System Musculoskeletal: iqolo, iintlungu apha entanyeni.
• ziphumo bezingalindelekanga Common: nokudumba peripheral kunye asthenia.

Njengoko ubona, "Moxonidine" iipilisi kunokubangela ukonakala imeko yesigulane. Ukuba iziphumo ebezingalindelekanga kugqame, ngoko ke ithamo amayeza kufuneka kupheliswa.

kuthetha yokuxhulumana kunye namanye amachiza

Ukuba iziyobisi "Moxonidine", "Moxonidine Sandoz" kunye nezinye analogue iziyobisi wanceda nomonde yaye akazange abangele ukuba yingozi ngakumbi, kufuneka kuthathwe kuphela kagqirha. Emva kokuba yolwamkelo ngaxeshanye isixhobo kunye namanye amayeza kunokubangela ngayo ezingafunekiyo. Yintoni kanye, siza kujonga ngoku.

ukusetyenziswa kwexesha-Enye "moxonidine" kweziyobisi kunye arhente ezifanayo umfutho kungabangela isiphumo additive.

Lakhula (tricyclics) ukunciphisa ukusebenza kweziyobisi umfutho inyathelo engundoqo. Kulo mba, azikho akukhuthazwa ukuba zisetyenziswe kunye into efana moxonidine.

umfowunelwa ndilolonga medicament ngokulula andzise iimpembelelo iziyobisi, lakhula tricyclic, kwakunye ethanol, hypnotics kunye nadlamkisayo.

Le into esebenzayo i medicament aphakathi okuncitshiswe kuphucula imisebenzi cognitive abantu ngaxeshanye bafumane lorazepam.

Nangona ukuqeshwa iziyobisi "Moxonidine" yaye "benzodiazepine 'ukuze siqinise yezabelo umthomalalisi le yokugqibela.

Iingcali zithi Moxonidine efunyanwa secretion tubular. Ngokuphathelele oku kufuneka isetyenziswe kunye iziyobisi nazo zizakubalulwa secretion tubular.

Ithuba yokumitha lokwaphusa (ukukhulelwa kunye zisanyisa)

Ngaba ixesha lokumitha ukuthatha amayeza "Moxonidine-LF"? Imiyalelo beziyobisi iqulathe ulwazi makulawulwe ngokungqongqo kunye nezifundo olwaneleyo malunga ngokhuseleko amayeza eziqwalaselwa ngethuba lokukhulelwa lwenziwa. Kungenxa yoko le nto kucetyiswa ukuba usebenzise olu didi kwizigulane.

Asinako ukuba ichiza "Moxonidine" kufuneka ingasetyenziswa ngexesha lokuncancisa. Oku kungenxa yokuba kubhaliwe yitsale ngobisi lukanina. Ukuba ngexesha zisanyisa chiza okwangoku sele amisiweyo, ngoko lwebele-lwebele kufuneka kupheliswa.

Kwinkqubo lezifundo (uvavanyo) kwizilwanyana, kwafunyaniswa ukuba medicament kuchaphazela embryotoxic.

isikhokelo ezithile ngokusebenzisa imithi

Ngokutsho imiyalelo apha, ngelixa ukusebenzisa iziyobisi "Moxonidine" kufuneka balumke ngokukhethekileyo. Ingakumbi kumayelana udidi eyahlukileyo kwizigulane. Ntoleyo, thina uchaze ngoku.

isilumkiso ekhethekileyo xa kufakwa "Moxonidine" medicament nibonwe kwizigulane kunye AV-kwafa 1 isidanga. Oku kungenxa yokuba abantu abanjalo kukho umngcipheko omkhulu bradycardia.

Kwakhona ekufumaneni ichiza kufuneka lwenziwe phantsi kweliso ugqirha kunye nesifo kakhulu Uqhaqho kwimithambo, ukusilela kwezintso kunye angina ezingazinzanga. Le nyaniso kungenxa yokuba ngamava ngokusebenzisa ichiza abanala makhwiniba ezinjalo akwanelanga.

Ukuba ufuna ukucima ukusetyenziswa ngaxeshanye iziyobisi 'moxonidine "beta-blocker, kufuneka kuqala ukucima okwetyeli lokugqibela, kwiintsuku ezimbalwa kamva - owesibini.

Ukuza kuthi ga ngoku akukho bungqina bokuba ukulisa "Moxonidine" iziyobisi kukhokelela ekwandeni uxinzelelo lwegazi. Noko ke, nakuba ukuba iingcali kunjalo Siyaleza ngezigaba le amayeza. Idosi kufuneka incitshiswe kwiiveki ezimbini ezidlulileyo.

ingaba ichiza kuchaphazela ukukwazi ukuqhuba yeziThuthi?

Ngethuba unyango kunye "Moxonidine" Abantu kufuneka balumke ngokukodwa xa besebenza imisebenzi eyingozi, kwakunye ngeli xesha uqhuba isithuthi. Oku kungenxa yokuba ichiza zinokuphazamisana yokwamkela yoxinaniso kunye lengqondo ngayo.

Analogs, kwaye iindleko ichiza

Thenga ichiza "Moxonidine" kwi ekhemesti ungakwazi ngaphandle kagqirha. Indleko yale chiza liphantsi kakhulu. Per pack, equlethe amacwecwe 14 kuya kufuneka ukuba uhlawule malunga 115-135 engange Russian.

Ukuba ngaba ucinga ichiza ningangeni, okanye nje baye bakwazi ukufumana ngayo ekhemesti, emva kokuba zithunyelwe specialist, le yokugqibela kuyanyanzeleka ukuncoma analogu iziyobisi. Phakathi la mayeza ndingathanda ukuqaqambisa ezi zilandelayo: "Fiziotenz", "Moxonidine-C3", "Moksarel", "Canon of Moxonidine", "Moksoniteks", "Moksogamma", "Tenzotran" njalo-njalo.

Thatha imali kufuneka ibe ngokungqongqo ingcebiso kagqirha. Kwakhona, phambi kokusebenzisa iyeza kufuneka babenolwazi imiyalelo apha.

Ichiza "Moxonidine": Ukubuyekezwa koogqirha kunye nezigulane

Ngokutsho iingcali, eli chiza lusebenza kakhulu lwegazi. Le mbono kwabelwana ngayo izigulane. Noko ke, abanye babo bakhalaza ukuba emva kokuthatha iipilisi emva komzuzwana bebonisa iziphumo ebezingalindelekanga ezifana yintloko, umlomo owomileyo, uvalo kunye isicaphucaphu. Kulo mzekelo, oogqirha bacebisa iyeza ukurhoxisa kwaye endaweni analogue wayo, nto leyo ikhuseleke ngenxa yempilo.