Mechanical ukukhula - ilikhubalo okanye ...

Indlela ekuthethwa ngayo kule ncwadi ka lolwazi, ngandlel 'ithile anokubanga isihloko' ilikhubalo kwicandelo abanxibe impahla. " Yintoni i "imimangaliso" imisebenzi "IFR" (Mechanical Growth Factor) kunye nokuba ngenene ilikhubalo? Ngaba yinyaniso into yokuba ixesha elifutshane lityelela rhoqo yokwenza umthambo uba imbaleki wiry sokumpompa? Makhe zama ukufumana iimpendulo zale mibuzo neminye.

Okokuqala, lo MGF-factor - oku kuthetha ukuba kwenza insulin-ezifana ukukhula (IGF), kwaye kanye, omnye ezahlukeneyo - IGF-1, ebizwa IGF-1Ec. ezwi wayo emzimbeni womntu kubangelwa uxinezelekile, ukwenzakala okanye ezinye iimpembelelo mechanical. iinkqubo ezichazwe kwenzeka imicu kwezihlunu waza wafumana igama eliqhelekileyo - ". mechanical ukukhula" Ethetha entsha "ilikhubalo lokunyanga bodybuilders," kufanele kuphawulwe ukuba MGF uye umahluko othile ukusuka IGF-1.

Ngokukodwa, umahluko ebalulekileyo mali asidi acid. Le peptide nomxokelelwane IGF-1 iqulathe 70, yaye IGF-1Ec - izifundo zokuqala 24. kuphela bacebise kunye receptors zahluke, bekunye imiba yokukhula. Kunika umdla ukuqaphela ukuba kunjalo kude akukho lwazi ozinzisiweyo ngomahluko phakathi isakhiwo IFR eveliswe umzimba womntu, esebenzisa isakhiwo zokwenziwa. Mechanical factor nokwanda uphando oluninzi. Kuyaphawuleka ukuba umbutho yokwanda izihlunu amandla kunye nomthamo ukuba isitofu kwemali uyaziwa kanye kuphela.

Oku kwenziwa ngo-2004 uProfesa Goldspinkom. It, sokuqhuba ii- namabuzi, uyakwazi ukunyusa i-25% cross-somhlathi imbono Imisonto yabo izihlunu, ezichaphazela MFR. Ezinye izifundo eziqhubekayo, oko kuphela iziphumo zilandelayo zifunyenwe: mechanical factor ukukhula ikhuthaza ukuphiliswa imicu ezonakeleyo. Ngenxa yoko, kuvula ezinye imibono zentliziyo kunye nakwezinye iindawo amayeza.

Ngoku lixesha lokuba aqhelane amagama afana "pegylation" ukususela ukufumana i MPR, umsebenzisi lidla ukufumana uguqulelo yakhe pegylated - isikhonkwane MGF. Oku ngokoqobo malunga inkqubo ethile, nto leyo evumela ukuba ukufihla kwemolekyuli kweziyobisi ukusuka kumajoni omzimba womntu okanye bayifake isuti yokuqala zokhuselo. Kwiimeko ezithile, isenzo esinjalo ngenxa yentswelo. Ngokomzekelo, amanye amachiza asetyenziswa ukunyanga umhlaza, ukuba pegylation.

Mechanical ukukhula bangenwe ewisa ngokukhawuleza. umsebenzi wayo ukuba neempembelelo iiseli lowo apho kuyo kuhlanganiswa eselumelwaneni, kunye PEGylation nga kwandisa ixesha layo ezinesiqingatha ubomi kumbandela imizuzu iiyure ezininzi. Nangona kunjalo, umbuzo malunga indalo kanye pegylated MFR na ongaqinisekanga ngayo. uphando elisesikweni isikhonkwane MGF ,, zaye singàphunyezwa Kuyabonakala ukuba, afumane iilinki elihle imithombo yolwazi na umntu akunakwenzeka ilawulwa.

Kaloku, ukuba niphikele ucinge ukuba iyeza loo mali okanye abaza kudalwa? Nakuba kulo mzekelo, akukho siqinisekiso sokuba into ngoomatshini pegylated ukukhula kwaye ngokuqhelekileyo aziyi kwahluka ekuziphatheni kwazo. Uninzi imiba malunga ichiza kufuneka okucingelwayo theoretical component kuphela. Iimveliso eziqulathe i IFR into esebenzayo, zange zaveliswa ukutyiwa abaninzi.

Sekunjalo, kufuneka icacise izibakala ezithile. inkampani ethile Belgian Anti-kweziyobisi waqhuba isifundo imixholo iibhotile ezimbini, nto leyo yawa ezandleni abaqeshwa balo. Kwathi kanti, isithako esisebenzayo kuzo - oku ngokwenene ngumba ngomatshini-ezifana ukukhula, yaye omnye nokuba sele ifunyenwe elebhu kunye nokusetyenziswa kwethekhinoloji ophezulu. Enye iyeza eveliswe unokwakhela kwaye engakhuselekanga eziqulathwe ukungcola.

Isiphelo: Namhlanje namnye zamazwe la amashishini amayeza, ukhupha ngokusemthethweni IFR. Ngokuthenga yindlela enjalo, umsebenzisi kwiimeko ezininzi iba njengentsomi, kodwa kuqulunqo ngoku kunokuba nemiphumo akucingeleki emzimbeni.