"Levocetirizine": imiyalelo zokusetyenziswa, inkcazo ichiza, analogue kunye nohlolo

Yimalini iziyobisi 'levocetirizine "? Ixabiso eli chiza iza kwenziwa ekupheleni. Uya kufunda kwakhona indlela yokusebenzisa ichiza, wathi luxelwa koogqirha kunye nezigulane, kwifomu apho ukuba ithengiswe kwaye zintoni na iimpawu.

Le fom nokwakhiwa kwamachiza ukuphakheja

Ukulungiselela "Levocetirizine Teva" ikhutshwa ngokohlobo amacwecwe. impahla yabo esebenzayo i levocetirizine dihydrochloride. Kwakhona eli chiza amacandelo ezincinane ngohlobo monohydrate lactose, microcrystalline kwincindi, nemagnesium stearate kunye dust colloidal.

Thenga le medicament banokuba iibhokisi zekhadibhodi, ezo zibekwe namadyungudyungu aluminiyam ku-7, 14 okanye 10 iipilisi.

pharmacodynamics beziyobisi

Yintoni iipilisi 'levocetirizine "? Imiyalelo yokusebenzisa ithi ubutyebi babo esebenzayo i isomer levorotatory ye cetirizine, leyo isebenza ochasene uyakhetha kakhulu kwaye elinamandla neuropathy H1-receptor.

iziyobisi kujongwa zingachaphazela phase reactions gistaminozavisimuyu kukwalisa, ukunciphisa yokufuduka eosinophils, ukunciphisa imithambo permeability kunye nokukhululwa mediators arhabaxa.

Oku kuthintela kuphela uphuhliso medicament kodwa attenuates ukuvuza negazi lakho. Kuye iipropati antipruritic kwaye anti-exudative kwaye anticholinergic oluncinane kunye antiserotoninovoe nempembelelo. Ngelo ngokwemithamo ekucetyiswa zonyango kweli chiza phantse akubangeli ukozela kunye silale.

Pharmacokinetics

Ziziphi iparameters entshukumo abe "levocetirizine" icwecwe? Imiyalelo yokusebenzisa ingxelo ukuba emva idosi enye ye amayeza ukusebenza yayo kwezonyango ngowe-50% ezigulane waphawula emva kwemizuzu 12-13 kwaye ngo-95% ezigulane - emva 60 imizuzu (isiphumo siyaqhubeka ngexesha Kwiintsuku ezilandelayo).

Le medicament iye pharmacokinetics yomgama. Ukuba nokudla oku ngokukhawuleza ezabalazela kungakhathaliseki ukuba ukutya ukutya.

Le bioavailability beziyobisi ifikelela 100%. Ukufumaneka ephezulu arhente esebenzayo waphawula emva kwemizuzu engama-55 emva kokungenisa, neprotini ndibopha nama-90%.

Drug lokugaya kwenzeka esibindini kwaye kwizondlo yi izintso ngokupheleleyo.

Ubungqina obubonakalayo buxela

"Levocetirizine" Amacwecwe kuboniswe ukuba unyango kwangumqondiso ezi zifo zilandelayo:

• pollinosis (okanye ekuthiwa hay fever);
• nokuthimliswa kunye conjunctivitis imvelaphi komzimba, ephelekwa ukurhawuzelela, lacrimation, rhinorrhea, ukuthimla, kunye anozizi le conjunctiva;
• angioedema;
• urticaria, kuquka idiopathic, ophuma kulo ifomu ezingapheliyo;
• dermatosis komzimba, obubonakala ngokuba yincwadi evuliweyo ukurhawuzelela kunye irhashalala.

Izimo

Hlobo luni Izimo kufuneka bazi phambi kokusebenzisa i "levocetirizine" icwecwe? Imiyalelo yokusebenzisa Ngokutsho kwezi nezithintelo, ezifana:

• ubudala umntwana ukuya kwiminyaka emithandathu;
• CRF ibe mibi;
• ngexesha lokukhulelwa;
• hypersensitivity leziyobisi lweziqalelo, kwaye waphawula ukuba piperazine kunye nezakhi zayo;
• ngexesha lokuncancisa.

Ngenyameko enkulu le medicament omiselwe CRF Iifomu aqine olulamileyo ngcathu, kwakunye ebudaleni (ngenxa unciphiso kunokwenzeka ukuhluza glomerular).

Drug "levocetirizine": imiyalelo yokusebenzisa

Ngokutsho ubugcisa, medicament esebenzayo lolawulo ngomlomo, kungakhathaliseki nasekusebenziseni ukutya. Ezi tablets kufuneka zithathwe ngamanzi ethafeni.

Abantwana abadala ngaphezu kweminyaka emithandathu, kwakunye izigulane abadala ekucetyiswa ngexesha elinye-iidosi 5 mg. Le idosi iphezulu ngosuku.

Ixesha eliqhelekileyo unyango ziiveki 3-6, ngokuxhomekeke ubukhali iimpawu. Xa sesichengeni emfutshane unyango allergen sinokuzaliswa ingadlulanga iveki.

Njengokuba iimeko ezinganyangekiyo, negazi, baye kufuna eli chiza iinyanga ezintandathu.

izigulane abadala kunye nabo isifo sesibindi akukho mfuneko ukunyenyisa idosi.

Xa oyidlayo isifo sezintso kufuneka zilungiswe ngokwale QC ogulayo:

• ngaphantsi kwe-10 ml ngomzuzu - ukufumana amayeza contraindicated;
• ngaphantsi kwe 30 ml ngomzuzu - 5 mg iintsuku 6;
• 30-49 ml ngomzuzu - 5 mg leentsuku 4;
• ngaphezulu kwama-50 ml ngomzuzu - 5 mg iintsuku-2.

ukusabela ezingalunganga

Yintoni iziphumo ebezingalindelekanga zingenzeka ngexesha uthatha iipilisi 'levocetirizine "? Iingcali Guest zithi abasabela ezibi zilandelayo:

• ukudinwa, intloko ebuhlungu, isiyezi, ukuba nochuku;
• ukozela, ukungaboni, iintlungu esiswini, intloko ebuhlungu;
• uza ukoma emlonyeni, ukuqunjelwa, dyspnea, nokudinwa;
• isicaphucaphu, ukutyeba, tachycardia;
• ziyabagulisa ezifana angioedema, ukungxama kakhulu eluswini, ukurhawuzelela, urticaria.

Iimpawu libanda

Xa abafumana ipilisi ngaphezu kwesinye ngosuku kubaguli abadala ukuphuhlisa ukozela, nabantwana - uchulumanco nexhala.

Uthomalaliso kweemeko ezinjalo lifinyele kunyango kwangumqondiso kunye esiswini lavage kunye otyiwa sorbents.

imithi

Ngaxeshanye lolwamkelo esikolweni "levocetirizine" ne "theophylline" kwi ne nedosi ye-400 mg, kunciphisa kugqitywe iyonke ye-16 yokuqala%, kodwa akazange lokutshintsha kinetics zale yokugqibela.

Xa abantu sensitive co-zolawulo isiyobisi kunye nezenzi zinqanda inkqubo luvo, kuquka ethanol, ukuze potentiate imiphumela Ukuncipha.

Ntonye, analogs, kwaye iindleko ichiza

Yintoni na le analogue iziyobisi 'levocetirizine "? Amathontsi for Ulawulo ngomlomo kunokuba neziphumo ezifanayo njengoko azipilisi le. Ngoko ke, ezinye iingcali bacebisa indawo ichiza ingqalelo ezifana iindlela njenge "Pollezin" yaye "Suprastineks" (amathontsi). Ukongeza, analogs kweli chiza le "Allertsetin ',' Zestril ',' Alerza", "Rolinoz", "Zirtek", "Zintset", "Tsetrin", "Allertek", "Zetrinal", "Amertil" "cetirizine" "Zodak", "Letizen S", "Parlazin".

Njengoko kuba ntonye, ngoko ukuze loo mayeza ziquka ezi zilandelayo: "Zodak" Allerset-L "," Zenaro "," levocetirizine "Sandoz", "Tsetrilev", "ka L-UMTS", "Tsezera", "Glentset", "Suprastineks" "Aleron" Express "," Ksizal ".

Ingaba eli chiza njenge "levocetirizine '? ixabiso layo uyahluka 170-290 engange.

baqinisekiswa

Uninzi ukubuyekeza ichiza "Levocetirizine-Teva" esihle. izigulane ezininzi rhoqo ubunzima ukusuka reactions ezahlukeneyo kukwalisa, ngokufuthi ukusebenzisa eli chiza. Bathi "levocetirizine" sisixhobo esisebenzayo hayi kuphela unyango ixesha elide, kodwa ndicela uncedo lokuqala kwimeko komzimba ngamaxesha athile okanye unyaka wonke. Le amalungiselelo ikuvumela ukugcina impilo kwinqanaba elifanelekileyo, ususe zonke iimpawu engasi nature komzimba.

Phakathi nohlolo ezimbi uyakwazi ukufumana abo apho sithi ukuba ichiza kubangela ukozela, ukudinwa yaye akhawuleze ukucaphuka. Oogqirha bathi xa nisamkela idosi echanekileyo ichiza reactions zidweliswe zinqabile kakhulu.

"Levocetirizine" okanye "Cetirizine": kuba kokona kulungileyo?

Lo mbuzo ucelwa izigulane ezininzi abaphethwe rhoqo evela negazi lakho. Iingcali ingxelo ukuba ababini banikezele ichiza ngempumelelo ukumelana nomsebenzi. Kodwa ke, njengokuba kusenziwa imiboniso, "levocetirizine" inshorensi tablet khipha inani elikhulu iimpawu komzimba.

Umntu athi "cetirizine" Kukho iindlela ezininzi zokukhupha (ilahla khona, amacwecwe, isiraphu). Oku kunegalelo kwaba lula ngakumbi ukusebenzisa, ingakumbi ebantwaneni (kwiminyaka emithandathu).