Iyeza 'Metoclopramide'. Imiyalelo yokusetyenziswa

Iyeza "i-Metoclopramide" (iipilisi) ibonwa njengento esebenzayo (ngokubhekiselele kuhlalutyo) kuthetha, oku kunceda ukunciphisa uxinzelelo lweemeko kwimvelaphi yesifo sesisu. Amachiza aboniswa kubini abadala kunye nabantwana. Njengomthetho, isicatshulwa sidluliselwa kakuhle.

Imiyalelo ye-ejenti "Metoclopramide" yokusetyenziswa ibhekisela kumachiza e-antiemetic, prokinetic, anti-icic.

Isilwanyana sinceda ekuvuseleleni umsebenzi weemoto kunye nokuqhelanisa umsebenzi wenxalenye yesigxina kwinkqubo yokutya, lawula ithoni yokuvalwa kwe-esophageal (sphincter) ekuphumleni. Amachiza akwandisa ukuphakama kunye neendlela zeengxaki zesisu (ngokukodwa i-antrum), ukuphucula i-sphincter yebbb ye-duodenum ne-pylorus, inyuse i-peristalsis kwaye ikhawuleze isantya sokukhupha. Xa uthatha isilwanyana "i-Metoclopramide" ibonisa ukugcinwa kwe-bile (ngenxa yokunyuka kwengcinezelo kwi-bile ne-bladder), iphelisa i-dyskinesia ye-gallbladder, kwaye iyanciphisa i-sphincter ye-Oddi.

Njenge- antiemetic, isicatshulwa siphumelele ukuhlanza kunye nesicathuko sezinto ezivela kwimvelaphi eyahlukeneyo. Imiqathango enjalo inokudibaniswa nokukhusela i-chemotherapy yomdlavuza, ukuphulwa kokutya, ukukhulelwa ("ukuhlanza kwabasetyhini abakhulelweyo"), ukulimala kwengqondo, intso kunye nesifo sebindi, imiphumo emibi yeziyobisi, i-anesthesia.

Amachiza asetyenziselwa ukuxhamla uhlobo oluthile lwemvelaphi, ukuphazamiseka kokusebenza ekutyeni, isifo se-reflux yesifo esiswini, ukuxhatshazwa kwesilonda se-peptic.

I-ejenti "i-Metoclopramide" imiyalelo yokusetyenziswa kwakhona ibonisa ukuba yimishanguzo efanelekileyo ye-migraine (ukukhusela i-nasusea, ukukhuthaza ukuxhatshazwa kwezidakamizwa ezichasene nemigudu yokulawulwa komlomo).

Sebenzisa iziyobisi kunye nokulungiselela amanyathelo okuxilongwa kwiphepha lesisu.

Kufuneka kuqatshelwe ukuba le nkunkuma ayinakusebenza ekuhlanjuleni ubuchoko bendalo.

Ukubonakalisa isilwanyana "i-Metoclopramide", umyalelo wokusetyenziswa ubonisa ubukho beempahla zayo ukucima umda kunye nempembelelo ye-apomorphine, ukwandisa umveliso weprolactin, ukukhuphula ukwanda kwexesha elide kwinqanaba le-aldosterone (ukugcinwa kwexesha elifutshane elifutshane). Xa uthabatha amayeza, kukho ukwanda kwenyameko kwi-acetylcholine.

Isisombululo sesilwanyana "I-Metoclopramide" (kwi-ampoules) ngokulawulwa kwe-intravenous iqala ukusebenza emva kwemizuzu emithathu, emva kweyunithi ye-intramuscular - emva kwemizuzu elishumi ukuya kwishumi elinesihlanu. Ngengeniso yomlomo (ngaphakathi), umphumo uqatshelwe emva kwemizuzu engamashumi amathathu ukuya kumashumi mathandathu. Ubungakanani bezenzo ngowomyalelo weyure enye okanye ezimbini.

Imiyalelo yokuchasana nesilwanyana "iMetoclopramide" imiyalelo yokusetyenziswa iquka i-stenosis pylorus, ukuphuma kumgudu wesisu, ukuxhamla, ukuguqulwa kwamathumbu emathumbu namathumbu. Musa ukunikezela ngamachiza e-glaucoma, ukuhluthwa (ngokunxulumene nobuchule bokunyuka kwamaxesha amaninzi kunye nobunzima bokuthinjelwa), i-pheochromocytoma, isifo se-Parkinson kunye nezinye iingxaki ze-extrapyramidal . Isidakamizwa esinconywayo "i-Metoclopramide" kwimeko ye-prolactin-dependence-free, kunye nangaphezulu kwiminyaka emibili.

Uhlobo lokungcola

Isilwayo "iMetroocamamide" simiselwe ngomlomo kathathu ngosuku malunga ne-5-10 milligram ngaphambi kokutya. Ukucetyiswa kwe-intravenous okanye ye-intramuscular kukucetyiswa kwisixa sama-milligram. Isilinganiselo somthamo omnye akufanele sibe ngaphezu kwee-milligrams ezingamashumi amabini, ngosuku-i-milligram.

Kubantwana abaneminyaka engaphezu kweminyaka emibili, umthamo usekwe ngugqirha ngokweminyaka yobudala.

Ngaphambi kokusebenzisa le nkunkuma "Metoclopramide" udinga ukubonisana nodokotela.