Drug "Armadin": imiyalelo zokusetyenziswa (izitofu)

Ukuza kuthi ga ngoku, ichiza "Armadin" liya ifumaneka yezonyango mihla. Imiyalelo yokusebenzisa (iinaliti - sixubushe imilo) zesixhobo kakhulu entsonkothileyo kuphuhliso, ngokunxulumene abaninzi bakhetha ukukhangela data ekhoyo ngakumbi.

Okulandelayo sijonga indlela sisixhobo, yintoni iingenelo zalo kunye neengxaki, ngokunjalo ukusebenzisa indlela eyiyo.

pharmacodynamics

"Armadin" yinto inhibitor ezizodwa yeenkqubo ezamahala-ezinkulu, yinto ngabakhuseli ndizayo. Xa inkqubo yokufumana kusho nootropic, antihypoxic, stressoprotektornoe kunye neziphumo anxiolytic, ichiza kwandisa kakhulu kwinkcaso impembelelo yeemeko ezahlukeneyo umonakalo kislorodzavisimym kunye namazwe zophendlo lwezifo.

Xa "Armadin" imiyalelo iziyobisi zokusetyenziswa (iinaliti) uphawula into yokuba ukusebenzisa iphucula flow yobuchopho igazi futhi umzimba yobuchopho, kunciphise udibaniso trombotsiotov, ukuphucula rheology igazi kunye microcirculation layo. Ngelo xesha linye oogqirha uluhlu edibanayo esebenzayo kuba yindlela eyabelwe ngenxa nokuzinziswa izakhiwo inwebu igazi iseli hemolysis xa, xa yokwamkela lwalo ngokunciphisa ukunxila iqala enzymatic kunye toxemia kwimeko pancreatitis ahlekise.

Zisebenza njani?

Kwanele uchaza lithetha "Armadin" indlela manual action lokufundisa (izitofu), Izimo, kunye namanye amanqaku. Ukusebenza kwalo kuthetha oko kubangelwa membranoprotektornym kunye neziphumo antioxidant. Xa inkqubo yokufumana umsebenzi nokunyuka dismutase superoxide elinganeno lipid peroxidation yandiswa ratio "lipid-protein", sehlise viscosity le inwebu, nokunyusa fluidity yayo. Ukongeza, nangokwamkela ichiza nga ukuliguquguqula umsebenzi enqanda ezahlukeneyo inwebu-bambopha receptor oluxandileyo, kunempembelelo entle ubuchule babo ukubophelela ligands kwaye lugcina umbutho noshowo kwaye olusebenzayo imifinya eziphilayo.

ingqalelo eyodwa kufuneka ihlawulwe yokuba ukuba ichiza "Armadin" umyalelo manual (iinaliti) ichaza iimpawu eziphambili ukusebenza kwayo zaza kananjalo kubonisa kuqheleke iinkqubo pathways kwi myocardium kobuchopho, sinciphise necrosis, unciphiso kunye nokuphuculwa emva komsebenzi zombane kunye contractility le myocardium, kwaye kwakhona ukunyuka kakhulu igazi flow coronary kwindawo kobuchopho. Ukufumana oku kuthetha inegalelo ulondolozo lwexesha elide iiseli ganglion semehlo kunye luvo optic xa neuropathy wenkqubela, leyo kungabangela hypoxia ezingapheliyo kunye ischemia.

Phakathi kwezinye imiphumela luphuculo wabalasela kumsebenzi olusebenzayo luvo optic kunye retina, nto leyo eyandisa acuity olubonakalayo lomntu.

Pharmacokinetics

Ngabaphethe intramuscular beziyobisi ixhomekeke esebenzisa kwi plasma yegazi iiyure ezingaphezu ezine. Ixesha lilonke ukufikelela C _lingu- phakathi malunga 0,45 ukuya kwi-0.5 lixa.

Kubalulekile ukuphawula ukuba ichiza ngokukhawuleza ekuqaleni ukuya ukusuka egazini ibe izicwili ezahlukeneyo kunye namaziko, kwaye emva koko kushenxiswa emzimbeni. Oku kwenzeka umchamo, kwiimeko ezininzi ifomu glyukuronkonyugirovannoy kuluncedo kwaye hi mpimo lowutsongo, kwaye ngendlela ingatshintshanga. Kungenxa kule ukulungiselela buguqulelwa oluthile "Armadin" (izitofu). Ukubunjwa esi sixhobo liquka emoxypine ngokukhawuleza wendele kwisiqwenga zesisu.

Emoxypine emzimbeni womntu uqala lokugaya kakhulu ngokuzimisela kunye nokwehlisa of glyukuronokonyugata yayo. Kwiimeko nenzuzo phezu nama-12 iiyure umchamo ifayileyemveliso malunga 0.3% iziyobisi ingaguqukanga, lo gama i-50% - kwifomu glyukuronokonyugata.

Le ngamandla eliphezulu eilmetilgidroksipiridina succinate kunye glyukuronokonyugatom wakhe kwazona ngethuba leeyure zokuqala ezine emva kokusebenzisa eli chiza. Lidla njengendlela "Armadin" (kuqhume) loogqirha reviews ziquka data zinomgutyulo kwi parameters umchamo lo element kunye metabolites yayo iyahluka Ukwahluka omkhulu ngamnye.

Xa kuthathwa kuyo?

Njengoko yaziwa, isixhobo ifumaneka iintlobo ezimbini - a kwizitofu standard kunye namacwecwe. ukhetho nganye isetyenziswa ezahlukeneyo amatyala, ngoko ke kufuneka uqonde kakuhle xa yaye yintoni uhlobo kungcono ukukhetha. Kwiimeko ezininzi oogqirha kuluncedo ngubani emiselweyo kwisixhobo, ifomu ngokuzimeleyo abonisa ulwamkelo lwayo.

izitofu

Ngu (ukudubula) iziyobisi "Armadin" La mazwi abonisa ukuba le ndlela ukusetyenziswa kwayo kuboniswe kwezi meko zilandelayo:

• ubukho ukuphazamiseka nokoyika ejikeleza yobuchopho kwinkqubo;
• imiphumo yokwenzakala ezahlukeneyo kwengqondo ebuhlungu;
• cardiopsychoneurosis;
• Encephalopathy;
• phambi kwayo nayiphi na ixhala disorder ngexesha percolation neurosis kunye namazwe bangonwabi;
• minor Ukuphazamiseka kwengqondo kwi sisiqalo ngenxa yamafutha;
• isenzeko zamabanga open engile neglaucoma izigaba ezahlukeneyo (kulo mzekelo ku ichiza "Armadin" (iinaliti) umyalelo ikhankanya ukuba ukusetyenziswa kwayo kuboniswa njengento ehlanganisiweyo therapy);
• Umfanekiso nokuqaleka kwimeko butywala, ukuba alawule iingxaki neurocirculatory kunye neurosis-like.

tablets

Olu hlobo ichiza kuyabonisa ngandlel ezahlukeneyo ukuze zisetyenziswe:

• neurosis okanye bangonwabi States ezineempawu ezahlukeneyo ixhala;
• imiphumo izifo ezihlasela zosulele ejikeleza yobuchopho kwinkqubo;
• cardiopsychoneurosis;
• genesis ezahlukeneyo Encephalopathy;
• Ukukhanya izifo ngokwasengqondweni yeGenesis ezahlukeneyo;
• imemori kakuhle, okanye ubukho intswelo yengqondo kubantu ebudaleni;
• ukulimala intloko ezingephi kunye neziphumo zazo;
• syndrome utywala absinentny phambi neurosis yawo okanye ukuphazamiseka nemithambo;
• iimeko asthenic ezahlukeneyo okanye bachatshazelwe izinto ezimbi;
• kamva imeko ukunxila kuqulunqwa iindlela ezahlukeneyo antipsihotropnymi;
• kwemithambo;
• Cardiology e kunyango zombini;
• dislipoproteinemia uhlobo atherogenic.

Njani izitofu?

Ngoko ke ugqirha emiselweyo ichiza "Armadin". Izitofu intramuscularly okanye butofelwe ilawulwa ukuze athontsize okanye jet. Ithamo kwimeko nganye zikhethwa kuphela usebenzisa le ndlela ngamnye, ukuze kufuneka kubanjwa ngoogqirha abaqeqeshiweyo.

Xa usebenzisa le ndlela zolawulo yokulungiselela ukumnika kufuneka ukuqhawula umtshato isisombululo sodium chloride nokomzimba. Kucetyiswa ukuba uqale unyango lwe abadala kunye amathamo ukusuka 50 ukuya 100 mg lulungiselelwayo amaxesha enye ukuya kwezintathu ngemini. angandiswa imiqulu Emva koku, okuboniswe ukuba ichiza "Armadin" (iinaliti) myalelo. Le ampoules ziqulathe ichiza ngokwayo, nekufuneka ilawulwe ngokucothayo ngapha 5-7 imizuzu jet, lo gama yedriphu "Armadin" yaziswa malunga ngesantya 40-60 tsakisi ngomzuzu. kunokwenzeka umthamo Ubuninzi yemihla ngemihla medicament ngu 800 mg.

Ukuba kukho naziphi na iintshukumo zokwaphulwa kwemithetho kwi isiyobisi yobuchopho inkqubo yokujikeleza etsolo unikwa ngexesha iintsuku 2-4 butofelwe abadala 200-300 mg qho kwiiyure ezingama-24 njengenxalenye kwanonyango ezinzima, emva kokuba isetyenziswa ngohlobo lwezitofu intramuscular kwi ne nedosi ye-100 mg kathathu ngemini. Kulo mzekelo, ubude unyango unako ukufikelela iintsuku ezilishumi elinesine.

Ukuba ukwenzakala cranial okanye neziphumo zazo ezahlukeneyo, ichiza isetyenziswa iintsuku 10-15 ngenaliti emthanjeni xa kukho umthamo izihlandlo ezingama-200 ukuya-500 mg 2-4 ngosuku.

Ukulungiselela "Armadin" (iinaliti) elawulwa kunye Encephalopathy semithambo decompensated apho isetyenziswa yegazi ngenaliti idriphu ngeedosi ka 100 mg kabini okanye kathathu ngemini kangangeentsuku ezili-14, emva koko isetyenziswa intramuscularly iiveki ezimbini 100 mg kabini ngemini. Ukongeza, ichiza asetyenziswe kwinkqubo kunye nothintelo ke Encephalopathy semithambo abadala ngabaphethe intramuscular ka 100 mg kabini ngosuku isithuba seentsuku ukususela kwi-10 ukuya kweli-14.

iposi engabalulekanga

Ukuba isigulane uye akaphathwa iqhosha etsolo engabalulekanga, ngoko ichiza "Armadin" (iinaliti) ilawulwa intramuscularly okanye butofelwe iintsuku ezili-14 kunye nonyango standard kuquka thrombolytics ezahlukeneyo, ACE inhibitors, lingaze, antiplatelet kunye arhente anticoagulant, kwakunye nitrate. Kwiintsuku zokuqala ezintlanu ukusetyenziswa kwayo ukuze kuphunyezwe kangangoko kunokwenzeka, kucetyiswa ukuba ukusebenzisa isixhobo yegazi. Kwiintsuku ezisithoba elandelayo sele ibonelela lolawulo intramuscular.

Ulawulo efakwa ikhutshwa phandle uvuza iimela, yaye eli chiza kufuneka ilawulwe kancinci ukuze kupheliswe umngcipheko yeziphumo ebezingalindelekanga. Le medicament ezisetyenziswa 0.9% isisombululo sodium chloride okanye isisombululo dextrose-5% xa kukho umthamo malunga 100-150 ml. Ukuqaliswa lwenziwa imizuzu 30-90. Ukuba kuyimfuneko, ichiza "Armadin" (iinaliti) ilawulwa bolus kade ukuba imizuzu emi-5.

Agent kufuneka ufakwe kathathu ngemini zonke iiyure ezisi-8. Le idosi yemihla ngemihla kwezonyango, kule meko isusela ukususela nge-6 ukuya ku-9 mg kwekilogram ubunzima bomzimba isiguli ngasinye, kunye idosi enye ye-, ngokulandelelana, 2.3 mg / ubunzima bomzimba kg. idosi iphezulu kunokwenzeka yonke imihla 800 mg, ngeli xesha omnye ekucetyiswa ukuba zilawulwa akukho mg ngaphezulu kwama-250.

nezinye izifo

Phambi syndrome utywala absinentnogo ichiza elo lilawulwa ne nedosi ye-100-200 mg intramuscularly kabini okanye kathathu ngemini, okanye ingasetyenziswa ukumnika efakwa amaxesha 1-2 ngosuku iintsuku 5-7, njengoko kubonisiwe esebenzisa "Armadin" Umsebenzisi isicelo (izitofu). Izimvo oogqirha futhi siphakamisa ukuba phambi ahlekise ukunxila antipsychotics ichiza kufuneka kwenziwa yegazi kuphela xa amathamo ezisukela 50 mg ukuya mg 300 imihla iintsuku 7-14.

Ukuba kukho naziphi na iinkqubo ukudumba kule ndlela kwisisu wabelwa ngomhla wokuqala libe ipreoperative, uze emva koko - njenge unyango postoperative. Kulo mzekelo, idosi iya kuxhomekeka ngqo kwi sifo ubungqongo kunye neefom kwaphakama, ikhondo ngokwasempilweni kunye nenkqubo kwasasazeka. Kufuneka kuqatshelwe ukuba ukuba kuyimfuneko, ukurhoxisa eli chiza kufuneka wenziwe ngokuthe ngcembe, yaye kuphela emva kokuba kufikelelwe imiphumo ngokuthe elihle zekliniki elabhoratri.

Xa yayiyazi edematous pancreatitis medicament lisetyenziswa ngeedosi ka 100 mg kathathu ngemini ngokuxhomekeke butofelwe okanye intramuscularly kwi kagqirha ukufunda.

oyi

ingqalelo eyodwa kufuneka sinikwe ukuqeshwa ichiza ukuba izigulane ukuba imbali komzimba. Kwiimeko ezithile, abantu sisifo sombefu kubantu phambi uvakalelo ngokugqithisileyo ukuba sulphate ibonakala uphuhliso iintshukumo eziqatha hypersensitivity. Emva siya ulawulo parenteral, ukuze kugcinwe isiphumo kuko luyakhuthazwa ukuba uqhubeke ukusetyenziswa isixhobo ngaphakathi ngokohlobo amacwecwe.

Akukho kakuhle elawulwa zophononongo malunga nokhuseleko kule ifasilithi yokwamkela ngexesha zisanyisa okanye ukukhulelwa singàphunyezwa, ukuze oogqirha azilukhuthazi besebenzisa oko ngeli thuba. Ngokufanayo, izifundo ziye luqhutywe malunga nokhuseleko beziyobisi ukusetyenziswa kwayo ukuze ukunyanga abantwana ngokunxulumene noko kubo kwakhona akunconywa ukusetyenziswa kwayo, nokuba xa kuthe izifo ngentla.

Ngaphezu koko, kubalulekile ukuqaphela ukuba ngexa unyango kuyimfuneko ukuba balumke kakhulu xa uqhuba izithuthi okanye iindlela ezahlukeneyo, njengoko kubonisiwe esebenzisa "Armadin" imiyalelo zokusetyenziswa (izitofu). Analogs beziyobisi badla kwahluka iziphumo ebezingalindelekanga efanayo. Oku, umzekelo, ezifana "Meksidol", "Mexicor", "Meksifin", "Neurox".

Phakathi ukusetyenziswa elide le medicament ochazwe ngazo inani elithile yeziphumo ebezingalindelekanga, kuquka ukudinwa, ukuqumba okanye nokudumba peripheral. Xa ufakwe yegazi (ingakumbi kunxulumene jet-inki) ukuze kubonakale into ebuntsimbi incasa emlonyeni, usi, imvakalelo ubushushu wonke umzimba, iyangongoza, tachycardia, ukuthoba ubuso kunye nenani ezinye iziphumo, nto leyo inxulunyaniswa ngesantya esiphezulu kakhulu ukuqaliswa yokulungiselela "Armadin" ( inaliti). Ukuphonononga bacebisa ukuba ezi ziphumo zimfutshane elide.