"Clozapine": imiyalelo ukusetyenziswa, analogue, ixabiso

umonzakalo ebuchotsheni, ntshikilelo, iimvakalelo, ukusebenzisa kakubi utywala, likhoboka neziyobisi, yofuzo - zonke ezi zinto zinokuba ngunobangela ngesifo kunye nezinye izifo zengqondo. Ukuze alungise le meko kwaye nokuphilisa abantu iingxaki ezinkulu ezifana kuya kunceda ichiza "Clozapine". Le yi-arhente antipsychotic ekufuneka isetyenziswe kuphela phantsi kweliso nolawulo ugqirha. Namhlanje, sifunde konke malunga amachiza: imilo iphumile, imiqathango yokusetyenziswa, analogue, ixabiso.

Xa kungaba luncedo?

imiyalelo "Clozapine" kweziyobisi ukwenzela ukusetyenziswa apho ifakwa faka, angasuswa xa ugqirha le miba ilandelayo:

- schizophrenia kulo naliphi na inqanaba;

- ngengqondo;

- zokulala;

- ukudana;

- lengqondo yokususa;

- izifo zengqondo nezokuziphatha.

Amacandelo, uhlobo wokukhutshwa, ilizwe wokwenziwa

Ilungu ephambili ichiza clozapine.

Yavelisa ichiza ngohlobo:

- amacwecwe 25, 50, 100 mg, uqiniseke unokuba 10, 50 okanye 100 iipilisi;

- granules abantwana (500 neepakethana mg);

- isisombululo ukuba isitofu (in a ampoule 2 ml).

Iveliswe amayeza e-Indiya, eRashiya, eJamani.

Imiyalelo yokusebenzisa iipilisi

Izikali "Clozapine" ichiza ibekwe ngamnye. Ngokubanzi, izinga yonke imihla ukususela 200 ukuya 400, ugqirha okokuqala unikela 25-50 mg, ngokuthe ngcembe kwisithuba seeveki-1 okanye ezi-2, wayezizuzisa idosi oyifunayo.

Emva kwekhosi iphambili unyango ugqirha unakho ukumisela unyango inkxaso, apho kuya kuba yimfuneko ukuthatha ukusuka mg-25 ukuya 200 iziyobisi.

iingedosi ezincinane yemihla ngemihla "Clozapine" imiyalelo iziyobisi ukusetyenziswa apho kufuneka isoloko kwiphakheji, ezithathwe:

- kakuhle kwezintso, hepatic okanye insufficiency intliziyo;

- izifo cerebrovascular;

- iingxaki yobuthongo.

Le idosi yemihla ngemihla akufuneki sibe ngaphezulu kwe-600 mg.

Imiyalelo zokusetyenziswa isisombululo kunye granules

Medicine "Clozapine" ingasetyenziselwa ngenaliti. iyeza Nurse kuqaliswa yegazi e ml-2.

Abantwana eli chiza ilawulwa njengesisombululo. Ukuze wenze oku, amaso kugalela ukusuka phasela iglasi, umgalele kubo 10 ml yamanzi baxhaya kakuhle. 1 reception ndingasela ukusuka mg-5 ukuya ku-20 ka iziyobisi, ngokuxhomekeke ubudala bomntwana. Nangona kunjalo, lo inani eliphezulu ngemihla zabantwana akufuneki sibe ngaphezulu kwe-100 yezisombululo "Clozapine". Ixesha elisikiweyo evela kugqirha - kuyimfuneko xa uthenga eli chiza xa naluphi na uhlobo ukukhululwa. Ngaphandle kwalo, ngaba ayinikiwe kuthengisa ichiza.

Izimo

Tablets "Clozapine 'ukuze zingasetyenziswa:

- nge uvakalelo ongqingqwa amacandelo ichiza;

- ngexesha sokuwa;

- kunye insufficiency nemithambo;

- ngexesha isithintelo yangasese;

- in hepatic, ukusilela kwezintso;

- ukuba isigulane akakwazi ukuba iimvavanyo zegazi qho;

- ngexesha kwengqondo utywala, ukunxila okanye isiyobisi;

- kunye granulocytopenia, agranulocytosis;

- xa States comatose;

- Women enxibe intliziyo abantwana, kwakunye nangexesha zisanyisa:

- amakhwenkwe kunye namantombazana ukuya kwiminyaka-5.

imiphumela izigelekeqe

"Clozapine" amayeza, imiyalelo zokusetyenziswa abaninzi ibonakala iyinto, kufuneka zithathwe ngononophelo. iziphumo ebezingalindelekanga eli chiza emva unyango zisenokwahluka, umzekelo:

- tachycardia, lwegazi, ukubanjwa sokuphefumla.

- isicaphucaphu, ukugabha, heartburn, iintlungu esiswini;

- ukwanda ubunzima bomzimba;

- ukozela, isiyezi, ukudinwa, lafa.

- umlomo owomileyo, ukuqhina, ukubila, iingxaki womchamo.

- irhashalala, dermatitis, nombala, urticaria.

libanda

Lithetha "Clozapine", analogue apho kuxoxwa ngezantsi, kufuneka kuthathwe ngqongqo kagqirha kagqirha. Kungenjalo, usenokuba iimpawu kabi ngisho eziyingozi libanda:

- isiphithiphithi;

- ukozela;

- waphazamiseka;

- yombono;

- coma;

- iingxaki umbono;

- tachycardia;

- ukudana zemigudu;

- ziwe.

Ukuba umntu wathabatha enkulu iindlela, qiniseka ukuba umncede. Nokunyangwa libanda, kuya kuba ngolu hlobo lulandelayo:

1. Yipule isisu.

2. Sela isebenze carbon.

3. Funa unyango.

iindleko

Medicament "Clozapine", ixabiso apho kuyahlukana nedlela kwifom yokhululo iziyobisi, amacwecwe idosi kunye nendawo kwikhemesti nodaka, ngalo mzuzwana kuthenga kunzima. Analogue esi sixhobo yi yokukhohlisa wayo, ndazikhamela. Ngapha koko, babeka ixabiso onesidima, ngoxa amayeza "Clozapine" ayibizi kakhulu. Ngoko ke, ngokuba 50 iipilisi kufuneka ahlawule imali engange 200. Ukuba uthathe granules abantwana, baya malini 1000 engange.

Unxibelelwano kunye namanye amayeza

Abantu abaninzi abazi ukuba kufuneka ulumke kakhulu ukuthatha amayeza "Clozapine". Iziyobisi ezinokuthi zisetyenziswe ngaxeshanye kunye ngale ndlela, kodwa ugxininiso logqirha:

- iipilisi ukuba gqiba inkqubo luvo - into yokuba ukwamkelwa engumzekelo zimali isiguli ukwandisa ukudakumba kweziko sokuphefumla;

- amayeza equlathe yokwakheka ethanol;

- iziyobisi, bemthoba uxinzelelo lwegazi;

- tablets ezibangela mielodepressiu ukusetyenziswa engumzekelo la machiza kunganqanda ithambo ngumongo krovetrovenie;

Kwakhona, nangononophelo olukhulu kuyimfuneko ukusebenzisa amayeza "Clozapine" kunye caffeine ngenxa yokunyuka kunokwenzeka iziphumo ebezingalindelekanga.

lokunye

"Clozapine" isasetyenziswa chiza, kwaye zininzi. Le ababambeleyo kakhulu ethandwayo ziquka amayeza ezinjalo, "Genodin", "Kvetiksol", "Kvetiron", "Nantarid" "Zalasta," "Zyprexa Zidis", "Parnasan", "Egolanza". Xa analogue ngqo isiphumo esifanayo ukuba beziyobisi "Clozapine" kodwa izinto esebenzayo baye kwabanye.

Drug "Kvetiksol"

Eli chiza Kwakhona oku kwenzelwa ukuba unyango ngesifo kunye namazwe manic.

Ikhupha iziyobisi ngendlela ipilisi. Eyona nto iphambili esebenzayo beziyobisi - quetiapine.

Usebenza amayeza kuphela ngokunxulumene kwizigulane abadala. Ngokuqhelekileyo, ithamo wamihla le kangangeentsuku ezine zokuqala akukho mg ngaphezulu kwama-300. Ugqirha Ungalungisa ukwandisa umthamo ichiza ukuya 450 mg ngosuku.

Amacwecwe Iindleko "Kviteksol" 25 mg (iipilisi 30) uya kuxabisa umntu engange-200. Ukuba uthenga ipilisi ngeedosi eziphezulu - 100 mg kwi ubungakanani, ngoko ke kufuneka ukuba uhlawule malunga 750 engange.

Drug "Zyprexa Zidis"

Oku kungenzeka bakhuphisane kakuhle ngeziyobisi umbuzo. Lithetha "Zyprexa Zidis" ikhutshwa ngohlobo amacwecwe, apho into esebenzayo usebenza olanzalin.

iipilisi Used kwezi meko zilandelayo:

- exacerbations unyango ngesifo sengqondo;

- therapy ithi zosulele manic;

- unyango lwe misinga.

Le idosi yemihla ngemihla kuzinza ngamnye, ngokuxhomekeke isifo yesigulane.

Kuba unyango ngesifo ekuqaleni unika ugqirha 10 mg kweziyobisi kanye ngemini.

Kuba unyango lwe mania etsolo Le yedosi Kucetyiswa yokuqala 15 mg 1 ixesha ngosuku.

Kodwa oku konke ixabiso unazo. Kuba kwirejimeni ezithile izifo ngasentla kufuneka udibane nogqirha.

Medicine "Zyprexa Zidis" kagqirha.

Indleko macwecwe 7 - 2500 engange. Oku kubiza kakhulu, unikwe ukuba iipilisi kuphela ngeveki kuya kuba yanele kwi kwiphakheji. Kwaye 28 iipilisi kufuneka ahlawule malunga 9000 engange.

Iveliswe ichiza UK.

Yintoni irejista amayeza?

Le nkqubo uxwebhu enika iinkcukacha ezibanzi malunga amachiza ezonyango. Ezi ziquka :. Isiqinisekiso sobhaliso, imiyalelo ukwenzela ukusetyenziswa, ukuze kuveliswe isiyobisi, njl Onke amachiza amatsha, kuquka amayeza "Clozapine", zifakiwe kubhaliso amayeza. Olu luhlu ikuvumela ukuba usebenzise igosa okanye ezinye iindlela.

Ke ukuba i "Clozapine" beziyobisi, iyafumaneka phantsi amagama zorhwebo eziliqela, nerejista bonke bephela ezibhaliweyo, umzekelo:

- Amayeza ze imvelaphi Ukrainian "Azaleprol".

- iziyobisi Swiss "leponeks".

- ipilisi Russian "Klozasten" yaye "Azaleptin".

Nganye kwezi mithi imeko yayo inombolo yobhaliso, umhla wokuphelelwa kunye nokuhlaziywa ukubhalisa.

Igama "Clozapine" izithethantonye lweziyobisi zidweliswe kuphela, ukuba amazwe. Kwaye kumachiza afana "Azaleprol", "leponeks", "Klozasten" yaye "Azaleptin 'ingqalelo avela kulo. Bona, iqulunqwe kwaye iphunyezwe kwilizwe elithile.

Drug "Azaleptin"

Oku kwakhona i amayeza antipsychotic, neuroleptic onyulwe schizophrenia, ithi manic, ukugula ngengqondo, ukuphazamiseka, ukuphazamiseka ngokweemvakalelo abantwana, njalo-njalo. N.

iziyobisi Iveliswe kwi Russian Federation.

KwiSimo "Azaleptin" ithetha enye umba kuphela, yaye elucwecweni 25 no 100 mg. Le into chiza esebenzayo - clozapine.

Malunga 420 engange ezazifuneka ukuze ndihlawulele amacwecwe-50 ka-25 mg lithetha "Azaleptin". "Clozapine" - amayeza, nto leyo lunikezelwa nqaku, kubalulekile amaxesha 2 enganeno.

iziyobisi "leponeks" Swiss

Le yenye ntonye le mali, ngubani na oqeshwe phantsi iingxaki zempilo efanayo. amayeza "leponeks 'Ifumaneka iintlobo ezimbini:

1. Amacwecwe.
2. A isisombululo ngenaliti.

Njengoko njengempembelelo esebenzayo ichiza owenza zonke clozapine efanayo. Elinye icwecwe "leponeks" lingaba 25 okanye 100 mg ingxenye enkulu. Kwaye izinto ezongezelelweyo zezi: wemagniziyam stearate, dust anhydrous, talc, umbona starch, polyvinylpyrrolidone, lactose.

Xa lokuqala unyango ngosuku lokuqala yabelwa 1 tablet (25 mg), 1 okanye u-2 phinda ngosuku. Ngosuku lwesibini - tablets-2. Kamva ugqirha ngokuthe ukwandisa ithamo de kutsho kuma - 300 mg.

Drug "leponeks" Kwakhona unalo ingxaki enye ecaleni, imida kwi nesicelo ichiza ingqalelo.

Iindleko kwezi tablets-25 mg lamaqhosha 50 1200 engange. Yaye 100 iipilisi ka 100 mg kufuneka ahlawule 5400 engange. Kuyinto okungakumbi njengendlela "Clozapine", ixabiso apho aya kuba nefikelelekayo kumntu wonke. Kubonakala ukuba ichiza "leponeks" kwiindidi ezithile labantu (abantu abahluphekileyo) ayifumaneki.

isiphelo

Kweli nqaku, wafunda ulwazi oluninzi umdla yaye iluncedo malunga ichiza "Clozapine". Imiyalelo yokusebenzisa, Izimo, ziziphumo ebezingalindelekanga, iindleko ziye ichaziwe. Saqonda ukuba eli chiza nucleoside ezininzi, nto leyo ukukhuphisana naye. Nangona kunjalo, ixabiso kwala machiza ngasentla. Noko ke, ezikhemisti, ezi analogue kudala andigweqe amayeza "Clozapine". Kodwa ukuba unethamsanqa elaneleyo ukuba ukuyifumana, ngoko okulungileyo gcina.