Nitrofurantoin: imiyalelo, ixabiso

Yintoni na le nto nje nitrofurantoin? Imiyalelo yokusebenzisa le element kuya thaca ngezantsi.

iipropati chemical

Ziziphi iimpawu ezi uphawu compound ezifana nitrofurantoin? Imiyalelo Sebenzisa ithi ukuba yemvelaphi nitrofuran. Kubonisa iipropati ucaca elwa. Kakhulu, iziyobisi kunye elilolo hlobo isetyenziselwa ukunyanga izifo kwindawo enzala.

iipropati Physical kunye nemilo

Yintoni nitrofurantoin? Imiyalelo isicelo amabango, nto leyo crystalline umgubo-orenji okanye omthubi, nto leyo iba incasa ethile ekrakra. Le ephindeneyo kakhulu kakuhle ezinyibilikayo nje kuphela ngamanzi kodwa utywala.

Ziziphi iindlela yakhululwa neziyobisi kunye icandelo njengoko nitrofurantoin? Ukuphonononga baxele ukuba ezo mali zenziwe ngohlobo amacwecwe amandla ezahlukeneyo. Kusenokwenzeka ukuba ama-camera okanye kuveliswa ngaphandle kwayo.

pharmacodynamics

Nitrofurantoin (ixabiso ichiza le nto iboniswa ngezantsi) ibonisa bactericidal kunye neempawu antibacterial. Le into abangaphangeliyo iinkqubo njini protein, ribonucleic kunye acids ideoxyribonucleic kwaye kucutha permeability of inwebu iseli kunye ubunzulu ukutya (aerobic) iintsholongwane eziyingozi.

Pharmacokinetics

Yintoni kwikinetiki iipropati ezithile ukuze enze icandelo ezifana nitrofurantoin? Imiyalelo Sebenzisa ithi le nto umthamo ophezulu kakhulu ukufunxeka. bioavailability yayo yi-50%. Ngaphezu koko, ukusetyenziswa ukutya kwandisa izinga.

Ngokutsho iingcali, elincane ziikristale of wathi kwemichiza compound, ngcono ke ukunyibilika kwaye ngenisa egazini.

Malunga ne-60% ye icandelo ekuthethwa ubotshiwe kwiiproteni plasma. umzimba wayo esiqwini isibindi, kunye nokuphelisa nakwisiqingatha ubomi malunga nemizuzu engama-25.

ubungqina

Amalungiselelo ne mba emiselweyo kwezi meko zilandelayo:

• Uthintelo kwi cystoscopy, catheterization, kunye nezinye utyando urologic kunye nophando.
• Unyango lwezifo kwinkalo enzala (umz, Ngokuzimela, pyelitis, pyelonephritis, urethritis).

Imingcele ukufumana

Nitrofurantoin ke contraindicated ukusebenzisa:

• xa oliguria;
• ezivakaliswa izifo zezintso;
• nokukhulelwa;
• Intliziyo ezinganyangekiyo okanye ukusilela kwezintso;
• ukungabikho glucose-6-phosphate dehydrogenase;
• aleji nomongo;
• ukuya kutsho kwinyanga enye ubudala;
• kohlobo okanye ukuqina kwesibindi;
• porphyria olunamandla;
• zisanyisa.

isilumkiso ekhethekileyo kufuneka ilandelwe izigulane isifuba inyumoniya, kwaye kukho utshintsho fibrotic kwi kwemiphunga.

Nitrofurantoin: imiyalelo yokusebenzisa

Iimveliso Price ne into esebenzayo ayikho phezulu kakhulu. Ukuba zakhutshwa ngohlobo amacwecwe, baye baqeshwa ngaphakathi, ukusela intabalala iziselo. Ngokuqhelekileyo, ezifana amachiza zilawulwa ukuba izigulane kwi umthamo 50-150 mg ukuya kane ngemini. Ikhosi konyango le arhente kufuneka kuhlala iintsuku 5-7.

Ithamo eliphezulu ndingatshatanga umntu omdala 0.3 grams ngosuku angasebenzisa ukuya ku 0.6 mg medicament.

Abantwana olu nyango emiselweyo 5-8 mg kwekilogram ubunzima bomzimba ngalinye. Idosi yemihla ngemihla ichiza umahlule ngo 4 amathamo lahlulwe.

Ukuba oyifunayo,-arhente ezifana unyango kuthi uyinikwe kwiintsuku ezili-10. Kodwa, oku kufuna ulawulo lwe inzalo umchamo.

icala izenzakalo

Emva kokufumana nitrofurantoin xa isigulane bangaziva:

• utyatyazo, hepatitis, syndrome cholestatic, pancreatitis, enterocolitis pseudomembranous;
• ukugabha, isicaphucaphu, isiyezi, intloko ebuhlungu;
• ukudinwa, arthralgia, nystagmus, myalgia, Njengokungeniswa anaphylactic;
• eosinophilia, syndrome volchanopodobny, irhashalala, kuthibaza;
• ukukhohlela, ifiva, ukozela, isithintelo inyumoniya, isisa ibele, ukungaqheleki umphunga Embi;
• iintlungu esiswini, peripheral neuropathy.

Nokusebenzisa ixesha elide ichiza kwandisa umngcipheko somhlaza nezintso.

izincomo ezithile

Abantu abane electrolyte ukungalingani, ianemia, isifo sezintso, kwakunye ukuswela iivithamini B abe okuba enkulu yokuba peripheral neuropathy.

Lo mbandela ndaba akusebenzi kule yonyango prostatitis, izifo neuron kwezintso kunye ubovu paranephritis.

Esi sixhobo ayifaneleki ukudibanisa kunye amayeza ukunika impembelelo embi kwi function zezintso.

Ixabiso kunye nohlaziyo

Njani amalungiselelo ineempahla ezifana nitrofurantoin? Ixabiso le ndlela ithandwa - "furadonin" - umalunga 120 engange.

Ngokutsho iimpendulo lezigulane ingxelo candelo uziphatha kakuhle Ngokuzimela. Nakuba kunjalo, kufanele kuqatshelwe ukuba ulwamkelo kunye amayeza nitrofurantoin badla kunokubangela intloko ebuhlungu, iintlungu esiswini, ukugabha kunye isicaphucaphu.